Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease

UMMS Affiliation

Program in Systems Biology; Department of Biochemistry and Molecular Pharmacology; Program in Bioinformatics and Integrative Biology



Document Type

Letter to the Editor

Medical Subject Headings

DNA; Genome, Human; Humans


Genetics and Genomics | Systems Biology


Comment on:

  • Getting "function" right. [Proc Natl Acad Sci U S A. 2014]
  • Defining functional DNA elements in the human genome. [Proc Natl Acad Sci U S A. 2014]

Rights and Permissions

Citation: Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33):E3366; doi: 10.1073/pnas.1410434111.


Full author list omitted for brevity. For the full list of authors, see article.

Related Resources

Link to Article in PubMed

Journal Title

Proceedings of the National Academy of Sciences of the United States of America

PubMed ID