Title
HiTC : Exploration of High-Throughput 'C' experiments
UMMS Affiliation
Program in Systems Biology
Date
11-1-2012
Document Type
Article
Medical Subject Headings
Chromosome Positioning; Chromosomes; DNA; Genomics; Nucleic Acid Conformation; Genetic Techniques
Disciplines
Bioinformatics | Genetics and Genomics | Systems Biology
Abstract
The R/Bioconductor package HiTC facilitates the exploration of high-throughtput 3C-based data. It allows users to import and export 'C' data, to transform, normalize, annotate and visualize interaction maps. The package operates within the Bioconductor framework, and thus offers new opportunities for future development in this field.Availability and Implementation: The R package HiTC is available from the Bioconductor web site. A detailed vignette provides additional documentation and help for using the package.
Comments
Citation: Bioinformatics. 2012 Nov 1;28(21):2843-4. doi: 10.1093/bioinformatics/bts521