This collection showcases journal articles and other publications authored by researchers in the Cancer, Stem Cell and Bone Biology Program, headed by principal investigators Gary S. Stein, Janet L. Stein, Jane B. Lian, and Andre J. van Wijnen, in the Department of Cell and Developmental Biology at the University of Massachusetts Medical School.

Submissions from 1998

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Preliminary crystallographic study of glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor AML-1/CBF-alpha2, Lei Tang, Bo Guo, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, Gary S. Stein, and G. Wayne Zhou (Journal of structural biology)

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Selective expression of specific histone H4 genes reflects distinctions in transcription factor interactions with divergent H4 promoter elements, Caroline M. J. van der Meijden, Patricia S. Vaughan, Ada Staal, Werner Albig, Detlef Doenecke, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen (Biochimica et biophysica acta)

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Cell cycle regulation of histone H4 gene transcription requires the oncogenic factor IRF-2, Patricia S. Vaughan, Caroline M. J. van der Meijden, Farah Aziz, Hisashi Harada, Tadatsugu Taniguchi, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (The Journal of biological chemistry)

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Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains, Congmei Zeng, Sandra Marie McNeil, Shirwin M. Pockwinse, Jeffrey A. Nickerson, Lindsay S. Shopland, Jeanne B. Lawrence, Sheldon Penman, Scott W. Hiebert, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 1997

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Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex, Chaitali Banerjee, Laura R. McCabe, Je-Yong Choi, Scott W. Hiebert, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo, Mark J. Birnbaum, Brigitte van Zundert, Patricia S. Vaughan, Alan J. Whitmarsh, Andre J. Van Wijnen, Roger J. Davis, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

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Functional properties of a conditionally phenotypic, estrogen-responsive, human osteoblast cell line, Peter V. N. Bodine, Jack Green, Heather A. Harris, Ramesh A. Bhat, Gary S. Stein, Jane B. Lian, and Barry S. Komm (Journal of cellular biochemistry)

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Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex, Baruch Frenkel, Casey Capparelli, Moira Van Auken, Daniel T. Baran, J. Bryan, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Endocrinology)

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YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene, Bo Guo, Fauzia Aslam, Andre J. Van Wijnen, Stefan G. E. Roberts, Baruch Frenkel, Michael R. Green, Hector F. DeLuca, Jane B. Lian, Gary S. Stein, and Janet L. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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ATF1 and CREB trans-activate a cell cycle regulated histone H4 gene at a distal nuclear matrix associated promoter element, Bo Guo, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Biochemistry)

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Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression, Jane B. Lian, Victoria Shalhoub, Fauzia Aslam, Baruch Frenkel, Jack Green, Michael Hamrah, Gary S. Stein, and Janet L. Stein (Endocrinology)

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Subcellular partitioning of transcription factors during osteoblast differentiation: developmental association of the AML/CBF alpha/PEBP2 alpha-related transcription factor-NMP-2 with the nuclear matrix, Danielle M. Lindenmuth, Andre J. Van Wijnen, Scott W. Hiebert, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Journal of cellular biochemistry)

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Stimulation of systemic bone formation induced by experimental blood loss, Tyler S. Lucas, Itai A. Bab, Jane B. Lian, Gary S. Stein, L. Jazrawi, R. J. Majeska, M. Attar-Namdar, and Thomas A. Einhorn (Clinical orthopaedics and related research)

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Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold, Shirwin M. Pockwinse, Gabriela Krockmalnic, Stephen J. Doxsey, Jeffrey A. Nickerson, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Sheldon Penman (Proceedings of the National Academy of Sciences of the United States of America)

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Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression, Hyun-Mo Ryoo, Heidi M. Hoffmann, T. L. Beumer, Baruch Frenkel, Dwight A. Towler, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, and Jane B. Lian (Molecular endocrinology (Baltimore, Md.))

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Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display, Hyun-Mo Ryoo, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Journal of cellular biochemistry)

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Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: inhibition by proliferating osteoblasts and osteosarcoma cells, Elisheva Smith, Baruch Frenkel, Timothy K. MacLachlan, Antonio Giordano, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Journal of cellular biochemistry)

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The osteocalcin gene: a model for multiple parameters of skeletal-specific transcriptional control, Gary S. Stein, Jane B. Lian, Andre J. Van Wijnen, and Janet L. Stein (Molecular biology reports)

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Cell cycle-dependent modifications in activities of pRb-related tumor suppressors and proliferation-specific CDP/cut homeodomain factors in murine hematopoietic progenitor cells, Andre J. Van Wijnen, Cathleen L. Cooper, Paul R. Odgren, Farah Aziz, Antonio De Luca, A. Rauf Shakoori, Antonio Giordano, Peter J. Quesenberry, Jane B. Lian, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

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Interferon regulatory factors: growth control and histone gene regulation--it's not just interferon anymore, Patricia S. Vaughan, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Journal of molecular medicine (Berlin, Germany))

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Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors, Congmei Zeng, Andre J. Van Wijnen, Janet L. Stein, Shari Meyers, Wuhua Sun, Lindsay S. Shopland, Jeanne B. Lawrence, Sheldon Penman, Jane B. Lian, Gary S. Stein, and Scott W. Hiebert (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 1996

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An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene, Chaitali Banerjee, Scott W. Hiebert, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site, Chaitali Banerjee, Janet L. Stein, Andre J. Van Wijnen, Baruch Frenkel, Jane B. Lian, and Gary S. Stein (Endocrinology)

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Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain, Baruch Frenkel, Martin A. Montecino, Jack Green, Fauzia Aslam, R. Desai, Chaitali Banerjee, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Endocrinology)

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Bone tissue-specific transcription of the osteocalcin gene: role of an activator osteoblast-specific complex and suppressor hox proteins that bind the OC box, Heidi M. Hoffmann, T. L. Beumer, Shamim Rahman, Laura R. McCabe, Chaitali Banerjee, Fauzia Aslam, J. A. Tiro, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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The osteocalcin gene promoter provides a molecular blueprint for regulatory mechanisms controlling bone tissue formation: role of transcription factors involved in development, Jane B. Lian, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Laura R. McCabe, Chaitali Banerjee, and Heidi M. Hoffmann (Connective tissue research)

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Developmental expression and activities of specific fos and jun proteins are functionally related to osteoblast maturation: role of Fra-2 and Jun D during differentiation, Laura R. McCabe, Chaitali Banerjee, R. Kundu, Robert J. Harrison, Paul R. Dobner, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Endocrinology)

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Expression of basic helix-loop-helix transcription factors in explant hematopoietic progenitors, Peter J. Quesenberry, Norman N. Iscove, Cathleen L. Cooper, Gerard Brady, Peter E. Newburger, Gary S. Stein, Janet L. Stein, G. Prem Veer Reddy, and Sonia Pearson-White (Journal of cellular biochemistry)

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Heterogeneity of colony stimulating factor-1 gene expression in the skeleton of four osteopetrotic mutations in rats and mice, Victoria Shalhoub, Mary E. Jackson, C. Paradise, Gary S. Stein, Jane B. Lian, and Sandy C. Marks Jr. (Journal of cellular physiology)

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Distinct conformations of vitamin D receptor/retinoid X receptor-alpha heterodimers are specified by dinucleotide differences in the vitamin D-responsive elements of the osteocalcin and osteopontin genes, Ada Staal, Andre J. Van Wijnen, Jan C. Birkenhager, Huibert A. P. Pols, Jean Prahl, Hector F. DeLuca, Marie-Pierre Gaub, Jane B. Lian, Gary S. Stein, Johannes P. T. M. van Leeuwen, and Janet L. Stein (Molecular endocrinology (Baltimore, Md.))

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Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements, Ada Staal, Andre J. Van Wijnen, Rajesh K. Desai, Huibert A. P. Pols, Jan C. Birkenhager, Hector F. DeLuca, David T. Denhardt, Janet L. Stein, Johannes P. T. M. van Leeuwen, Gary S. Stein, and Jane B. Lian (Endocrinology)

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Nuclear structure and function, Gary S. Stein and Ronald Berezney (Journal of cellular biochemistry)

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Transcriptional control of osteoblast growth and differentiation, Gary S. Stein, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Martin A. Montecino (Physiological reviews)

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Functional interrelationships between nuclear structure and transcriptional control: contributions to regulation of cell cycle- and tissue-specific gene expression, Gary S. Stein, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, and Martin A. Montecino (Journal of cellular biochemistry)

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Transcriptional control of cell cycle progression: the histone gene is a paradigm for the G1/S phase and proliferation/differentiation transitions, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, and Jane B. Lian (Cell biology international)

Control of cell cycle regulated histone genes during proliferation and differentiation, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, and Gary S. Stein (International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity)

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Acidic fibroblast growth factor inhibits osteoblast differentiation in vitro: altered expression of collagenase, cell growth-related, and mineralization-associated genes, Kam-Tsun Tang, Casey Capparelli, Janet L. Stein, Gary S. Stein, Jane B. Lian, Anna C. Huber, Lewis E. Braverman, and William J. DeVito (Journal of cellular biochemistry)

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CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F, Andre J. Van Wijnen, Maria F. van Gurp, Marleen C. De Ridder, Cristina Tufarelli, Thomas J. Last, Mark J. Birnbaum, Patricia S. Vaughan, Antonio Giordano, Krek Wilhelm, Ellis J. Neufeld, Janet L. Stein, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 1995

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Contributions of distal and proximal promoter elements to glucocorticoid regulation of osteocalcin gene transcription, Fauzia Aslam, Victoria Shalhoub, Andre J. Van Wijnen, Chaitali Banerjee, Rita Bortell, A. Rauf Shakoori, Gerald Litwack, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Molecular endocrinology (Baltimore, Md.))

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Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3, Mark J. Birnbaum, Andre J. Van Wijnen, Paul R. Odgren, Thomas J. Last, Guntram Suske, Gary S. Stein, and Janet L. Stein (Biochemistry)

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Control of 1,25-dihydroxyvitamin D3 receptor-mediated enhancement of osteocalcin gene transcription: effects of perturbing phosphorylation pathways by okadaic acid and staurosporine, Rajesh K. Desai, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Endocrinology)

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The nuclear matrix protein NMP-1 is the transcription factor YY1, Bo Guo, Paul R. Odgren, Andre J. Van Wijnen, Thomas J. Last, Jeffrey A. Nickerson, Sheldon Penman, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Proximal promoter binding protein contributes to developmental, tissue-restricted expression of the rat osteocalcin gene, Arianne A.J. Heinrichs, Rita Bortell, Michael Bourke, Jane B. Lian, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

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In vivo occupancy of histone gene proximal promoter elements reflects gene copy number-dependent titratable transactivation factors and cross-species compatibility of regulatory sequences, Paul E. Kroeger, Andre J. Van Wijnen, Urs Pauli, Kenneth Lynn Wright, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

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Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation, Jane B. Lian and Gary S. Stein (The Iowa orthopaedic journal)

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The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization, Maureen P. Lynch, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Experimental cell research)

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Properties of blood-contacting surfaces of clinically implanted cardiac assist devices: gene expression, matrix composition, and ultrastructural characterization of cellular linings, Michael J. Menconi, Shirwin M. Pockwinse, Thomas A. Owen, Kurt A. Dasse, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoter, Harold L. Merriman, Andre J. Van Wijnen, Scott W. Hiebert, Joseph P. Bidwell, Edward G. Fey, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Biochemistry)

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Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization, Shirwin M. Pockwinse, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Experimental cell research)

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Histone H4 proximal promoter mediates a complex transcriptional response during differentiation of 3T3L1 adipocytes, Anna L. Ramsey-Ewing, Rita Bortell, Gary S. Stein, and Janet L. Stein (Journal of cellular physiology)

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Expression of cell cycle regulatory factors in differentiating osteoblasts: postproliferative up-regulation of cyclins B and E, Elisheva Smith, Baruch Frenkel, Robert Schlegel, Antonio Giordano, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Cancer research)

Molecular mechanisms mediating control of cell cycle and cell growth, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, and Peter J. Quesenberry (Experimental hematology)

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Contributions of nuclear architecture to transcriptional control, Gary S. Stein, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, and Martin A. Montecino (International review of cytology)

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Genetic and environmental factors in premenstrual symptom reporting and its relationship to depression and a general neuroticism trait, O.B.A. Van Den Akker, F. F. Eves, Gary S. Stein, and R. M. Murray (Journal of psychosomatic research)

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Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2, Patricia S. Vaughan, Farah Aziz, Andre J. Van Wijnen, Shujian Wu, Hisashi Harada, Tadatsugu Taniguchi, Kenneth J. Soprano, Janet L. Stein, and Gary S. Stein (Nature)

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Bipartite structure of the proximal promoter of a human H4 histone gene, Kenneth Lynn Wright, Mark J. Birnbaum, Andre J. Van Wijnen, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

Submissions from 1994

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Differential effects of warfarin on mRNA levels of developmentally regulated vitamin K dependent proteins, osteocalcin, and matrix GLA protein in vitro, Leesa M. Barone, Michael A. Aronow, Melissa S. Tassinari, Donna Conlon, Ernesto Canalis, Gary S. Stein, and Jane B. Lian (Journal of cellular physiology)

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Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells, Joseph P. Bidwell, Edward G. Fey, Andre J. Van Wijnen, Sheldon Penman, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Cancer research)

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Parathyroid-responsive modifications in the nuclear matrix of ROS 17/2.8 rat osteosarcoma cells, Joseph P. Bidwell, Andre J. Van Wijnen, Chaitali Banerjee, Edward G. Fey, Harold L. Merriman, Sheldon Penman, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Endocrinology)

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Subnuclear distribution of the vitamin D receptor, Joseph P. Bidwell, Andre J. Van Wijnen, Edward G. Fey, Harold L. Merriman, Sheldon Penman, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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Cortical bone osteocalcin content and matrix composition in autosomal dominant osteopetrosis type I, J. Bollerslev, Sandy C. Marks Jr., L. Mosekilde, Jane B. Lian, Gary S. Stein, and L. Mosekilde (European journal of endocrinology / European Federation of Endocrine Societies)

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TGF beta 1 prevents the down-regulation of type I procollagen, fibronectin, and TGF beta 1 gene expression associated with 3T3-L1 pre-adipocyte differentiation, Rita Bortell, Thomas A. Owen, Ronald A. Ignotz, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

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TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype, Ellen C. Breen, Ronald A. Ignotz, Laura R. McCabe, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Journal of cellular physiology)

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In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells, Ellen C. Breen, Andre J. Van Wijnen, Jane B. Lian, Gary S. Stein, and Janet L. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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A pilot study of postnatal depression following caesarean section using two retrospective self-rating instruments, Denzil R.L. Edwards, Sally-Ann M. Porter, and Gary S. Stein (Journal of psychosomatic research)

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Replication of an osteopetrosis-inducing avian leukosis virus in fibroblasts, osteoblasts, and osteopetrotic bone, Rosalinda Gram Foster, Jane B. Lian, Gary S. Stein, and Harriet L. Robinson (Virology)

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A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements, Baruch Frenkel, Martin A. Montecino, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits differentiation of normal diploid rat osteoblasts in vitro, John F. Gierthy, J. B. Silkworth, Melissa S. Tassinari, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins, Heidi M. Hoffmann, Katrina M. Catron, Andre J. Van Wijnen, Laura R. McCabe, Jane B. Lian, Gary S. Stein, and Janet L. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Aberrant gene expression in cultured mammalian bone cells demonstrates an osteoblast defect in osteopetrosis, Mary E. Jackson, Victoria Shalhoub, Jane B. Lian, Gary S. Stein, and Sandy C. Marks Jr. (Journal of cellular biochemistry)

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Responsiveness of gene expression markers of osteoblastic and osteoclastic activity to calcitonin in the appendicular and axial skeleton of the rat in vivo, Louis G. Jenis, Boonsong Ongphiphadhanakul, Lewis E. Braverman, Gary S. Stein, Jane B. Lian, Robert A. Lew, and Daniel T. Baran (Calcified tissue international)

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Influence of DNA replication inhibition on expression of cell growth and tissue-specific genes in osteoblasts and osteosarcoma cells, Maaike Kockx, Laura R. McCabe, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Journal of cellular biochemistry)

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Expression of cell growth and bone phenotypic genes during the cell cycle of normal diploid osteoblasts and osteosarcoma cells, Laura R. McCabe, Thomas J. Last, Maureen P. Lynch, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Journal of cellular biochemistry)

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Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription, Anna L. Ramsey-Ewing, Andre J. Van Wijnen, Gary S. Stein, and Janet L. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Variations in vitamin D receptor transcription factor complexes associated with the osteocalcin gene vitamin D responsive element in osteoblasts and osteosarcoma cells, A. Rauf Shakoori, Andre J. Van Wijnen, Rita Bortell, T. A. Owen, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Journal of cellular biochemistry)

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Abnormalities of phosphoprotein gene expression in three osteopetrotic rat mutations: elevated mRNA transcripts, protein synthesis, and accumulation in bone of mutant animals, Victoria Shalhoub, B. Bettencourt, Mary E. Jackson, Carole A. MacKay, M. J. Glimcher, Sandy C. Marks Jr., Gary S. Stein, and Jane B. Lian (Journal of cellular physiology)

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Transcriptionally active nuclei isolated from intact bone reflect modified levels of gene expression in skeletal development and pathology, Victoria Shalhoub, Rita Bortell, Mary E. Jackson, Sandy C. Marks Jr., Janet L. Stein, Jane B. Lian, and Gary S. Stein (Journal of cellular biochemistry)

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Histone gene transcription: a model for responsiveness to an integrated series of regulatory signals mediating cell cycle control and proliferation/differentiation interrelationships, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, and Jane B. Lian (Journal of cellular biochemistry)

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Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation, Gary S. Stein, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Joseph P. Bidwell, and Martin A. Montecino (Journal of cellular biochemistry)

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Cell cycle controlled histone H1, H3, and H4 genes share unusual arrangements of recognition motifs for HiNF-D supporting a coordinate promoter binding mechanism, Fusinita M. I. van den Ent, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Journal of cellular physiology)

Submissions from 1993

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Inhibition of induced endochondral bone development in caffeine-treated rats, Leesa M. Barone, Melissa S. Tassinari, Rita Bortell, Thomas A. Owen, J. Zerogian, K. Gagne, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components, Joseph P. Bidwell, Andre J. Van Wijnen, Edward G. Fey, Steven I. Dworetzky, Sheldon Penman, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Constitutive transcription of the osteocalcin gene in osteosarcoma cells is reflected by altered protein-DNA interactions at promoter regulatory elements, Rita Bortell, T. A. Owen, Victoria Shalhoub, A Heinrichs, Michael A. Aronow, C Rochette-Egly, Y Lutz, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene, Baruch Frenkel, Jolanda Mijnes, Michael A. Aronow, Gerard Zambetti, Chaitali Banerjee, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Biochemistry)

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Identification and characterization of two proximal elements in the rat osteocalcin gene promoter that may confer species-specific regulation, Arianne A.J. Heinrichs, Chaitali Banerjee, Rita Bortell, Thomas A. Owen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter, Arianne A.J. Heinrichs, Rita Bortell, Shamim Rahman, Janet L. Stein, Emad S. Alnemri, Gerald Litwack, Jane B. Lian, and Gary S. Stein (Biochemistry)

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1 alpha,25-dihydroxyvitamin D3-induced changes in intracellular pH in osteoblast-like cells modulate gene expression, Louis G. Jenis, Jane B. Lian, Gary S. Stein, and Daniel T. Baran (Journal of cellular biochemistry)

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Effect of gallium nitrate in vitro and in normal rats, Louis G. Jenis, Catherine E. Waud, Gary S. Stein, Jane B. Lian, and Daniel T. Baran (Journal of cellular biochemistry)

The developmental stages of osteoblast growth and differentiation exhibit selective responses of genes to growth factors (TGF beta 1) and hormones (vitamin D and glucocorticoids), Jane B. Lian and Gary S. Stein (The Journal of oral implantology)

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Etidronate inhibits the thyroid hormone-induced bone loss in rats assessed by bone mineral density and messenger ribonucleic acid markers of osteoblast and osteoclast function, Boonsong Ongphiphadhanakul, Louis G. Jenis, Lewis E. Braverman, Sharon Alex, Gary S. Stein, Jane B. Lian, and Daniel T. Baran (Endocrinology)

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Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements, T. A. Owen, Rita Bortell, Victoria Shalhoub, A Heinrichs, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Proceedings of the National Academy of Sciences of the United States of America)

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Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis, Shirwin M. Pockwinse, Jeanne B. Lawrence, Robert H. Singer, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Bone)

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Multiple copies of the bone-specific osteocalcin gene in mouse and rat, Shamim Rahman, Annette M. Oberdorf, Martin A. Montecino, Susan M. Tanhauser, Jane B. Lian, Gary S. Stein, Philip J. Laipis, and Janet L. Stein (Endocrinology)

Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells, A. Rauf Shakoori, Thomas A. Owen, Victoria Shalhoub, Janet L. Stein, M. Bustin, Gary S. Stein, and Jane B. Lian (Journal of cellular biochemistry)

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Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype, Gary S. Stein and Jane B. Lian (Endocrine reviews)

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Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: reciprocal regulation of cell cycle-controlled and bone-related genes, Fusinita M. I. van den Ent, Andre J. Van Wijnen, Thomas J. Last, Rita Bortell, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Cancer research)

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Nuclear matrix association of multiple sequence-specific DNA binding activities related to SP-1, ATF, CCAAT, C/EBP, OCT-1, and AP-1, Andre J. Van Wijnen, Joseph P. Bidwell, Edward G. Fey, Sheldon Penman, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Biochemistry)

Submissions from 1992

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Vitamin D-responsive protein-DNA interactions at multiple promoter regulatory elements that contribute to the level of rat osteocalcin gene expression, Rita Bortell, T. A. Owen, Joseph P. Bidwell, P. Gavazzo, Ellen C. Breen, Andre J. Van Wijnen, Hector F. DeLuca, Janet L. Stein, Jane B. Lian, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

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Differential regulation of H4 histone gene expression in 3T3-L1 pre-adipocytes during arrest of proliferation following contact inhibition or differentiation and its modulation by TGF beta 1, Rita Bortell, Andre J. Van Wijnen, Anna L. Ramsey-Ewing, Gary S. Stein, and Janet L. Stein (Journal of cellular biochemistry)

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Acidic fibroblast growth factor modulates gene expression in the rat thyroid in vivo, Jean-Pierre Chanoine, Gary S. Stein, Lewis E. Braverman, Victoria Shalhoub, Jane B. Lian, Chris A. Huber, and William J. DeVito (Journal of cellular biochemistry)