Regulation of specific genes during the cell cycle. Utilization of homologous cDNAs and cloned sequences for studying histone gene expression in human cells
UMass Chan Affiliations
Department of Cell BiologyDocument Type
Journal ArticlePublication Date
1980-12-01Keywords
Base Sequence*Cell Cycle
Chromosomal Proteins, Non-Histone
Cloning, Molecular
*Gene Expression Regulation
Histones
Humans
Interphase
Models, Genetic
Nucleic Acid Hybridization
RNA, Messenger
Transcription, Genetic
Cell Biology
Metadata
Show full item recordAbstract
Evidence for differential gene expression during the cell cycle and approaches for studying cell-cycle-stage specific gene expression are summarized. Attention is focused on regulation of histone gene expression during the cell cycle of continuously dividing cells and after stimulation of nondividing cells to proliferate. The level(s) at which control of histone gene expression occurs and the possible involvement of chromosomal proteins in the regulation of histone gene expression are discussed. The preparation of cloned human histone sequences and their use in studying the structural and functional properties of human histone genes are presented. Index Entries: Cell cycle, gene regulation during; gene regulation, during the cell cycle; regulation of specific genes, during the cell cycle; DNAs, homologous, and histone gene expression; cloned DNAs, and histone gene expression; histone gene expression; gene expression, histone; cloned human histone sequences.Source
Cell Biophys. 1980 Dec;2(4):291-314. Link to article on publisher's siteDOI
10.1007/BF02785095Permanent Link to this Item
http://hdl.handle.net/20.500.14038/49507PubMed ID
6163542Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1007/BF02785095