Title

Representation of mRNA sequences in normal and SV40 transformed human diploid fibroblasts

UMMS Affiliation

Department of Cell Biology

Date

1-1-1981

Document Type

Article

Medical Subject Headings

Base Sequence; Cell Line; Cell Transformation, Viral; DNA; Diploidy; Fibroblasts; Histones; Humans; Kinetics; *Nucleic Acid Hybridization; Poly A; RNA, Messenger; Simian virus 40

Disciplines

Cell Biology

Abstract

The representation of mRNA sequences in normal and SV40-transformed WI-38 human diploid fibroblasts was examined. Variations in the hybridization of polysomal RNAs to 3H-labeled DNAs complementary to poly A+ mRNA of normal and SV40-transformed cells suggest differences in the mRNA populations. a comparison of the representation of histone RNA sequences of normal and SV40-transformed human diploid cells did not reveal significant differences.

Rights and Permissions

Citation: Anticancer Res. 1981;1(2):89-92.

Related Resources

Link to Article in PubMed

PubMed ID

6287906

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