Representation of mRNA sequences in normal and SV40 transformed human diploid fibroblasts
Department of Cell Biology
Medical Subject Headings
Base Sequence; Cell Line; Cell Transformation, Viral; DNA; Diploidy; Fibroblasts; Histones; Humans; Kinetics; *Nucleic Acid Hybridization; Poly A; RNA, Messenger; Simian virus 40
The representation of mRNA sequences in normal and SV40-transformed WI-38 human diploid fibroblasts was examined. Variations in the hybridization of polysomal RNAs to 3H-labeled DNAs complementary to poly A+ mRNA of normal and SV40-transformed cells suggest differences in the mRNA populations. a comparison of the representation of histone RNA sequences of normal and SV40-transformed human diploid cells did not reveal significant differences.
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Citation: Anticancer Res. 1981;1(2):89-92.
Shephard, Elizabeth A.; Jansing, R. L.; Phillips, Ian R.; Stein, Janet L.; and Stein, Gary S., "Representation of mRNA sequences in normal and SV40 transformed human diploid fibroblasts" (1981). Stein, Stein, Lian, vanWijnen Lab Publications. 166.
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