The Senior Scholars Program at the University of Massachusetts Medical School (UMMS) provides medical students with an opportunity for scholarly activities that serve not only as an introduction to the philosophy of research based on answering questions through hypothesis generation, information gathering, experimentation, and critical interpretation, but as a tool for growth in an evidence-based health care environment. UMMS Senior Scholars have completed projects in all major fields of basic science, clinical medicine, epidemiology, and public health. Many have presented their findings at local, regional or national meetings, serving as a platform for subsequent academic endeavors. Each student participates in "Senior Scholars Presentation Day" preparing a poster and sharing ideas with medical school peers and faculty members. This collection includes student posters, abstracts, and published journal articles authored by Senior Scholars.

Read the UMassMedNow feature about the 2013 Senior Scholars Presentation Day!


Publications from 2008

Improving Breastfeeding Outcomes at the Family Health Center of Worcester, Ellen Green

Trends in the Use of Echocardiography and Left Ventriculography in Patients Hospitalized with Acute Myocardial Infarction: The Worcester Heart Attack Study, Samuel W. Joffe

Bile Metabolism and Cholelithiasis (A comprehensive review for the monthly publication Clinics of North America), Stephanie Lambou-Gianoukos

The Use of Accelerometers to Predict Functional Outcome After Total Knee Arthroplasty, Craig Lareau


Feasibility of Using Near Infrared Spectroscopy in Determining VO2 for Preoperative Risk Assessment, Nathan Marengi

Characteristics of Patients Utilizing St. Anne’s Free Clinic, Candice McElroy

Inflammatory Patterns and Cellular and Vascular Permeation in Rat Abdominal Wall Defects Using Alloderm, Permacol and CollaMend for Repair, Joyce K. McIntyre

Clinical Health Informatics Meets Medical Education, Jeffrey Phillips


Cyclic or Congenital Neutropenia: Phenotypic Variations of Blood Neutrophil Counts in Patients with the Same ELA2 Mutation and Same Paternal Haplotype: Evidence for Phenotype Determination by Modifying Genes, Talia Pindyck

Creation of a Clinical Assay for Detection of Mycobacterium Tuberculosis Infection as Well as Rifampin Resistance Using Linear-After-The-Exponential PCR (LATE-PCR), Kevin Soares

Fine Mapping the Genetic Basis of CRP Regulation in African Americans: a Bayesian Approach, Lakshman Subrahmanyan

Publications from 2007


Transthoracic Echocardiographic Measurement of the Ascending Aorta in Bicuspid Aortic Valve Patients: A Simple Standardized Method, Alfred Albano


ED Diagnosis of Acute Coronary Syndromes: No Gender-Related Difference of 'Chest Discomfort', Garreth C. Biegun

Altered Serum Zinc Concentration in Patients with Visceral Leishmaniasis (L. donovani) and Healthy Regional Controls from Bihar, India: A Correlation with Susceptibility to Disease, Stephen Carpenter


Expanded services for the prevention of mother-to-child HIV transmission: field acceptability of a pilot program in Lusaka, Zambia, Benjamin H. Chi, Namwinga Chintu, Alison Lee, Elizabeth M. Stringer, Moses Sinkala, and Jeffrey S. A. Stringer

“Marrow for Tomorrow:” A Community-Based Public Health Partnership in Worcester’s Medically Under-Served Communities, Andrew Geller


Polypharmacy Prevalence in the Treatment of Unipolar Depression, Anna Glezer


Early edema in warfarin-related intracerebral hemorrhage, Joshua M. Levine, Ryan Snider, David Finkelstein, Mahmut E. Gurol, Rishi Chanderraj, Eric E. Smith, Steven M. Greenberg, and Jonathan Rosand

Risk Profile for Pregnancy in Adolescent Patients in the Blackstone Valley, Suzanne MacKay

Expression of Vascular Endothelial Growth Factor Subtypes in Mammary Invasive Ductal Carcinoma and their Relationship to Tumor Progression, Katherine F. Maloney

ICD Under-Utilization in Primary Prevention Patients, Matthew McGuiness


The Diagnostic and Therapeutic Utility of the Scoop-Shave for Pigmented Lesions of the Skin, Gary W. Mendese


Assessing the Role of Education in Women’s Knowledge and Acceptance of Adjunct HPV Testing for Cervical Cancer Screening, Debra Papa, Tiffany A. Moore Simas, Megan Reynolds, and Hannah Melnitsky

Increasing Cervical Lesion Identification in Junior Practitioners after Abnormal Cervical Cytology: A Computer-Based Colposcopy Tutorial, Patricia Seymour

Obstacles to Follow After Abnormal Cervical Cytology at an Urban Health Center in Worcester, MA, Patricia Seymour

Quantification of the Association Between the Apparent Diffusion Coefficient and Age in Normal Pediatric Hips, Katharine Taylor

Appendicitis and Appendectomy in Overweight and Obese Patients, H. Ruby Wang

Evaluation of the Safety and Pharmacokinetics of Clostridium difficile Toxin A Human Monoclonal Antibody and Clostridium difficile Toxin B Human Monoclonal Antibody Given Alone or in Combination in Healthy Adults, Hilary Womble

Publications from 2006

Examining the Role of Palliative Procedures in Patients with Stage IV GI Cancers, Nathan J. Aranson


Prediction of successful voiding immediately after outpatient mid-urethral sling, Kenneth I. Barron, Judith A. Savageau, Stephen B. Young, Lisa C. Labin, and Abraham N. Morse

First Trial of Intensive Glycemic Control in Critically Ill Emergency Department Patients, Jennifer E. Cyrkler


Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KIT, Rosemary Foster, Steven Solano, Jennifer Mahoney, Arlan Fuller, Esther Oliva, and Michael V. Seiden


Pilot study of methods to document quantity and variation of independent patient exercise and activity after total knee arthroplasty, Patricia D. Franklin, Joseph McLaughlin, Catherine B. Boisvert, Wenjun Li, and David C. Ayers

A Qualitative Study of the Collaboration between Health Care Providers and Lawyers within the Family Advocates of Central Massachusetts Program, Allison M. Hargreaves

Cardiac Resynchronization Therapy: What's Ticking at UMass, Matthew Hitron

A comparison of exercise-induced hematocrit (Hct) changes between non-invasive infrared sensors (NIRS) and venous blood draws, Kenneth E. Johnson

The Effect of Split versus Combined Therapy in Medication Compliance of Psychiatric Patients, Eric Kosinski


Serum Glucose Levels and Hospital Outcomes in the Setting of Acute Myocardial Infarction in Patients Not Known to Have Diabetes: A Community-Wide Perspective, Daniel G. Kramer

Structure Based Drug Design: Inhibition of E6 protein in immortalized HPV cell lines implicated in human epithelial cancers, Nicole R. LeBoeuf

MassHealth Primary Care Services Assessment Tool, Matthew Logalbo


Documenting Quantity and Variation in Patient-Managed Exercise and Activity after Total Knee Replacement, Joseph McLaughlin


Frequency of Ascending Aorta Replacement: A Description of 105 Patients with Bicuspid Aortic Valve Undergoing Aortic Valve Replacement, Elizabeth C. Mitchell


ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose), Alan R. Morrison, Joel Moss, Linda A. Stevens, James E. Evans, Caitlin Farrell, Eric Lee Merithew, David G. Lambright, Dale L. Greiner, John P. Mordes, Aldo A. Rossini, and Rita Bortell

National Patterns of Immediate Breast Reconstruction for Neoplastic Disease, Jaisa Olasky

Determination of Cystic Fibrosis Frequency Among Newborns Diagnosed with Meconium Ileus and other Bowel Obstruction, Allison Paroskie


Magnetic resonance imaging of tissue and vascular layers in the cat retina, Qiang Shen, Haiying Cheng, Machelle T. Pardue, Thomas F. Chang, Govind Nair, Van Toi Vo, Ross D. Shonat, and Timothy Q. Duong


Use of computed tomography to predict failure of nonoperative treatment of unilateral facet fractures of the cervical spine, Leo R. Spector, David H. Kim, Jesse Affonso, Todd J. Albert, Alan S. Hilibrand, and Alexander R. Vaccaro

Investigation of Noninvasive Near-Infrared Spectroscopic Sensor for Measurement of Blood Hematocrit, Anh T. Tran


The Influence of Message Framing on Adolescent Females' Intention to Obtain Chlamydia Screening, Andrea B. Urban

The Effect of Age on Postoperative Pain Medication Requirements Following Vaginal Reconstructive Surgery, Kenneth Walton

Publications from 2005

Femur flap for tibial reconstruction: % Circumference Required to Convey a Mechanical Advantage over the Fibula, Genevieve Bartels


Magnetic Resonance Imaging of Anatomical Layer Specificity in the Cat Retina, Thomas F. Chang


Readability of informed-consent forms used in mental health research, Paul P. Christopher

Emotional Health and Level of Post-Total Knee Arthroplasty Exercise, Peter DeNoble

Analysis of Acute Perihematomal Edema in Warfarin-Related Intracerebral Hemorrhage, David Finkelstein

The Association Between Serum Cholesterol Levels and Suicidal Thoughts and Behaviors, Kathryn Fleming-Ives


Virtual Microscopy: Potential Applications in Medical Education and Telemedicine in Countries with Developing Economies, Paul Fontelo, Ernest DiNino, Krista Johansen, Ashraf Khan, and Michael Ackerman

Association between Emotional and Physical Health and Resource Utilization after Total Knee Arthroplasty, Michael Kelly


Uterine Papillary Serous Carcinoma and Endometrioid Carcinoma: Novel Immunostains with Respect to Clinical-Pathologic Factors, Emily Ko


Is a Paleolithic Age Diet an Optimal Diet for Modern Human Beings?, Lauren McClure

Irradiation Upregulates EGFR and Survivin in Non Small Cell Lung Cancer Cells, Joshua Meyer


A Lymphocyte Surface Protein Produces the Signaling Molecule Poly (ADP-ribose) from NAD, Alan R. Morrison

Expanding the Indications: Titanium Elastic Nailing of Femur Fractures in Children Under Six, Robert Nascimento

The Use of Flexible Funds for Respite Services in a Managed Care Wraparound Program, Joseph O'Garr

Gamma-synuclein is a marker for retinal ganglion cell loss in glaucoma, Dustin Pomerleau


Analysis of axillary coverage during tangential radiation therapy to the breast, Julia Reznik, Maria Giulia Cicchetti, Barbara Degaspe, and Thomas J. Fitzgerald

Pediatric Hospice: The career potential for pediatric residents and a comparison between systems in UK and US, Nicola Smith

Publications from 2004

The Role of Nitric Oxide in the Anti-adrenergic Effects of Adenosine in Isolated Perfuse Rat Hearts, George Cancel

A Beta Test of a Computer-Assisted Instruction Module in Improving Dermatologic Physical Exam Skills in Third Year Medical Students, Konstantinos Deligiannidis


The Effect of Epidural Anesthesia on Oncologic Outcomes After Surgery for Colon and Rectal Cancer, Jaimee DeMone

Construction of a Virtual Microscope that can Accurately Assess Diagnoses Rendered Over the Web, Ernest DiNino

Investigation of the Approach to Tracking Cardiac Catheterization Complication, Michele Manzon


The Effect of Facial Fractures on the Treatment and Outcome of Trauma Patients Presenting with Acute Cervical Spine Fractures, Andrea Marvin


Characteristics of patients at three free clinics, Rachel Mott Keis, Linda Gifford DeGeus, Suzanne B. Cashman, and Judith A. Savageau

Bicycle Riding Associated Erectile Dysfunction: Treatment Outcome of Surgery, Andrew Nisbet


Survey of breast-feeding practices and outcomes in the cystic fibrosis population, Eliza M. Parker, Brian P. O'Sullivan, Julie C. Shea, Meredith M. Regan, and Steven D. Freedman

Prescription Trends of Angiotensin Converting Enzyme Inhibitors (ACEi) and Angiotensin Receptor Blockers (ARBs) as Estimated in the National Ambulatory Medical Care Survey (NAMCS), Benjamin Prentiss

CXCL12 expression in murine stomach regions, & lack of correlation between its expression and H.felis-induced gastritis and gastric carcinoma, Thomas Tadros

Nutritional and Weight Status of Job Corps Students, Eric Wallace

Publications from 2003


Sex differences in survival after acute myocardial infarction in patients with diabetes mellitus (Worcester Heart Attack Study), Amber Crowley, Vandana Menon, Darleen M. Lessard, Jorge L. Yarzebski, Elizabeth A. Jackson, Joel M. Gore, and Robert J. Goldberg

Publications from 2002


Liquid ventilation with perflubron in the treatment of rats with pneumococcal pneumonia, Eric W. Dickson, Stephen O. Heard, Thomas E. Tarara, Jeffry G. Weers, Angela B. Brueggemann, and Gary V. Doern


Comparative effects of unfractionated heparin and low molecular weight heparin on vascular endothelial cell tissue factor pathway inhibitor release: a model for assessing intrinsic thromboresistance, YouFu Li, Miguel Rodriguez, Frederick A. Spencer, and Richard C. Becker


Bone density in competitive figure skaters, Christina V. Oleson, Brian D. Busconi, and Daniel T. Baran


Use of meperidine in patient-controlled analgesia and the development of a normeperidine toxic reaction, Thomas T. Simopoulos, Howard S. Smith, Christine Peeters-Asdourian, and Donald S. Stevens


Delta opiates increase ischemic tolerance in isolated rabbit jejunum, Robert J. Tubbs, William A. Porcaro, Won Jae Lee, David J. Blehar, Robert E. Carraway, Karin Przyklenk, and Eric W. Dickson

Publications from 2001


Psychosocial effects of enhanced external counterpulsation in the angina patient: a second study, Susan Springer, Alison Fife, William Lawson, John C. K. Hui, Lina Jandorf, Peter F. Cohn, and Gregory Fricchione

Publications from 1999


Polyplex-mediated gene transfer into human retinal pigment epithelial cells in vitro, Edward Chaum, Mark P. Hatton, and Gary Stein


Scattering of primary care: doctor switching and utilization of health care by children on fee-for-service Medicaid., Gavin P. Joffe, Lance E. Rodewald, Teresa Herbert, Richard Barth, and Peter G. Szilagyi


Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS), John B. Levine, Jiming Kong, Mark Nadler, and Zuoshang Xu


Characteristics of cartilage engineered from human pediatric auricular cartilage, Angela Rodriguez, Yi Lin Cao, Clemente Ibarra, Stephen Pap, Martin Vacanti, Roland D. Eavey, and Charles A. Vacanti

Publications from 1998


Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension, Helen Christou, Atsushi Yoshida, Victoria Arthur, Toshisuke Morita, and Stella Kourembanas


Partial liquid ventilation with perfluorocarbon in the treatment of rats with lethal pneumococcal pneumonia, Eric W. Dickson, Stephen O. Heard, Benson Chu, Armando E. Fraire, Angela B. Brueggemann, and Gary V. Doern


Hypoxic responses of vascular cells, Stella Kourembanas, Toshisuke Morita, Helen Christou, Yuxiang Liu, Hideo Koike, Dara Brodsky, Victoria Arthur, and S. Alex Mitsial

Publications from 1997


The microvenous valvular anatomy of the human dorsal thoracic fascia, Seyedhossein Aharinejad, Raymond M. Dunn, Gary M. Fudem, Adam Vernadakis, Peter Böck, Wilhelm Firbas, and Sandy C. Marks