Sluder Lab Publications

Title

Centriole biogenesis: a tale of two pathways

UMMS Affiliation

Department of Cell Biology

Date

7-3-2007

Document Type

Article

Medical Subject Headings

Animals; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Centrioles; Drosophila; Embryo, Nonmammalian; Female; Humans; Models, Biological; Ovum

Disciplines

Cell Biology

Abstract

Two recent studies in Drosophila demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles, but can also drive de novo centriole assembly in unfertilized eggs that initially lack centrioles. These studies offer a new perspective on the mechanisms that control centriole duplication.

Rights and Permissions

Citation: Nat Cell Biol. 2007 Jul;9(7):736-8. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

17603508