Title

Heterogeneity and hypothesis testing in neuropsychiatric illness

UMMS Affiliation

Shriver Center

Date

6-26-2008

Document Type

Article

Medical Subject Headings

Genetic Heterogeneity; Neuropsychiatry; Neuropsychological Tests

Disciplines

Mental and Social Health | Neuroscience and Neurobiology | Psychiatry and Psychology

Abstract

The confounding effects of heterogeneity in biological psychiatry and psychiatric genetics have been widely discussed in the literature. We suggest an approach in which heterogeneity may be put to use in hypothesis testing, and may find application in evaluation of the Crespi & Badcock (C&B) imprinting hypothesis. Here we consider three potential sources of etiologic subtypes for analysis.

Rights and Permissions

Citation: Deutsch, C. K., Ludwig, W. W., & McIlvane, W. J. (2008). Heterogeneity and hypothesis testing in neuropsychiatric illness. Behavioral and Brain Sciences, 31, 266-267. DOI: 10.1017/S0140525X08004275