Heterogeneity and hypothesis testing in neuropsychiatric illness
Medical Subject Headings
Genetic Heterogeneity; Neuropsychiatry; Neuropsychological Tests
Mental and Social Health | Neuroscience and Neurobiology | Psychiatry and Psychology
The confounding effects of heterogeneity in biological psychiatry and psychiatric genetics have been widely discussed in the literature. We suggest an approach in which heterogeneity may be put to use in hypothesis testing, and may find application in evaluation of the Crespi & Badcock (C&B) imprinting hypothesis. Here we consider three potential sources of etiologic subtypes for analysis.
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Citation: Deutsch, C. K., Ludwig, W. W., & McIlvane, W. J. (2008). Heterogeneity and hypothesis testing in neuropsychiatric illness. Behavioral and Brain Sciences, 31, 266-267. DOI: 10.1017/S0140525X08004275