Gadoxetate disodium-enhanced liver MRI: gallbladder opacification patterns during hepatobiliary phase

UMMS Affiliation

Department of Radiology



Document Type


Medical Subject Headings

Contrast Media; Gadolinium DTPA; Gallbladder; Humans; Liver; Magnetic Resonance Imaging; Retrospective Studies; Tissue Distribution




OBJECTIVE(S): To describe the different patterns of gallbladder lumen opacification on gadoxetate disodium-enhanced liver magnetic resonance imaging (MRI).

METHODS: One hundred eighty-seven MRI examinations were reviewed by two abdominal imaging radiologists who described the different patterns of gallbladder opacification, based on comparing the post-contrast to the pre-contrast images.

RESULTS: Four patterns of gallbladder opacification were identified, all based on the anti-dependent distribution of the excreted biliary contrast inside the gallbladder lumen. Contrast was identified at the level of the gallbladder neck, anti-dependant wall, and gallbladder fundus. One gallbladder completely filled with contrast.

CONCLUSION(S): The opacification of the gallbladder lumen follows a distinctive anti-dependent distribution.

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Citation: Clin Imaging. 2014 Jan-Feb;38(1):42-9. doi: 10.1016/j.clinimag.2013.09.005. Link to article on publisher's site. Epub 2013 Oct 18.

Related Resources

Link to Article in PubMed


Eovist, Gadoxetate disodium, Gallbladder opacification, MR cholangiography

PubMed ID