The vision of the Department of Quantitative Health Sciences (QHS) at the University of Massachusetts Medical School is to improve population and individual health by transforming health care delivery through methodological innovation and to become a nationally and internationally recognized resource for translational research. The Department has a three-pronged mission: (1) to fulfill the quantitative health science needs of the academic medical center as it moves towards its vision of becoming a leader in clinical and translational research; (2) to train the next generation of scientists that will fulfill the Vision; and (3) to weave service to the academic medical center into discovery of new approaches to solve the health care needs of the nation and world. This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Department of Quantitative Health Sciences.

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Publications from 2009

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Post-hospital medical respite care and hospital readmission of homeless persons, Stefan G. Kertesz, Michael A. Posner, James J. O'Connell, Stacy Swain, Ashley N. Mullins, Michael Shwartz, and Arlene S. Ash

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Self-monitoring of blood glucose with finger tip versus alternative site sampling: effect on glycemic control in insulin-using patients with type 2 diabetes, Philip E. Knapp, Kara M. Showers, Jenna C. Phipps, Jeanne L. Speckman, Elliot Sternthal, Karen M. Freund, Arlene S. Ash, and Caroline M. Apovian

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Relationship of early life stress and psychological functioning to blood pressure in the CARDIA study, Barbara J. Lehman, Shelley E. Taylor, Catarina I. Kiefe, and Teresa E. Seeman

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Disparities in self-monitoring of blood glucose among low-income ethnic minority populations with diabetes, United States, Deborah A. Levine, Jeroan J. Allison, Andrea Cherrington, Joshua S. Richman, Isabel C. Scarinci, and Thomas K. Houston

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Abdominal obesity and peripheral vascular disease in men and women: a comparison of waist-to-thigh ratio and waist circumference as measures of abdominal obesity, Bing Lu, Jing Zhou, Molly E. Waring, Donna R. Parker, and Charles B. Eaton

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The relation between body size perception and change in body mass index over 13 years: the Coronary Artery Risk Development in Young Adults (CARDIA) study, Elizabeth Lynch, Kiang Liu, Gina S. Wei, Bonnie Spring, Catarina I. Kiefe, and Philip Greenland

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How might infant and paediatric immune responses influence malaria vaccine efficacy, Ann M. Moormann

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Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen 1 and thrombospondin-related adhesive protein immunodominant epitopes in a highland population from Western Kenya, Ann M. Moormann, Peter Odada Sumba, Daniel J. Tisch, Paula E. Embury, Charles H. King, James W. Kazura, and Chandy C. John

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Value-Based Insurance Design in the Medicare Prescription Drug Benefit: An Analysis of Policy Options, Lisa Murphy, Avalere Health, Ruth E. Brown, Erika Heaton, Tanisha Carino, A. Mark Fendrick, Michael E. Chernew, and Allison B. Rosen

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Ventricular dilation: association with gait and cognition, Walter M. Palm, Jane S. Saczynski, J. van der Grond, Sigurdur Sigurdsson, Olafur Kjartansson, Palmi V. Jonsson, Gudny Eiriksdottir, Vilmundur Gudnason, Faiza Admiraal-Behloul, Lenore J. Launer, and Mark A. van Buchem

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Serological evidence for long-term Epstein-Barr virus reactivation in children living in a holoendemic malaria region of Kenya, Erwan Piriou, Rhonda Kimmel, Kiprotich Chelimo, Jaap M. Middeldorp, Peter Odada Sumba, Robert Ploutz-Snyder, Ann M. Moormann, and Rosemary A. Rochford

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Pharmaceuticals companies' medication assistance programs: potentially useful but too burdensome to use, Maria Pisu, Joshua Richman, Jeroan J. Allison, O. Dale Williams, and Catarina I. Kiefe

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Disparities in use of a personal health record in a managed care organization, Douglas W. Roblin, Thomas K. Houston, Jeroan J. Allison, Peter J. Joski, and Edmund R. Becker

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Challenges in building disease-based national health accounts, Allison B. Rosen and David M. Cutler

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Patient adherence: a blind spot in cost-effectiveness analyses, Allison B. Rosen, Alicen Spaulding, Dan Greenberg, Jennifer A. Palmer, and Peter J. Neumann

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Clinical features, treatment practices, and hospital and long-term outcomes of older patients hospitalized with decompensated heart failure: The Worcester Heart Failure Study, Jane S. Saczynski, Chad E. Darling, Frederick A. Spencer, Darleen M. Lessard, Joel M. Gore, and Robert J. Goldberg

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Trends in atrial fibrillation complicating acute myocardial infarction, Jane S. Saczynski, David D. McManus, Zheng Zhou, Frederick A. Spencer, Jorge L. Yarzebski, Darleen M. Lessard, Joel M. Gore, and Robert J. Goldberg

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Transforming Continuing Healthcare Education with E-Learning 2.0, Rajani S. Sadasivam, K. Crenshaw, V. Datla, and M. Scheon

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A Service-Based Entropic Model for Sensors Orchestration, Rajani S. Sadasivam, Ravikumar Goli, Rajesh Kathiru, Adisesh Krishnan, Stanley Thompson, Yalcin Tuncer, and Murat M. Tanik

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Genetic region characterization (Gene RECQuest) - software to assist in identification and selection of candidate genes from genomic regions, Rajani S. Sadasivam, Gayathri Sundar, Laura K. Vaughan, Murat M. Tanik, and Donna K. Arnett

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Composite Process-Personalization with Service-Oriented Architecture, Rajani S. Sadasivam and Murat M. Tanik

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Are co-morbidities associated with guideline adherence? The MI-Plus study of Medicare patients, Anne E. Sales, Edmund F. Tipton, Deborah A. Levine, Thomas K. Houston, Yongin Kim, Jeroan J. Allison, and Catarina I. Kiefe

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Characteristics that predict physician participation in a Web-based CME activity: the MI-Plus study, Michael J. Schoen, Edmond F. Tipton, Thomas K. Houston, Ellen Funkhouser, Deborah A. Levine, Carlos A. Estrada, Jeroan J. Allison, O. Dale Williams, and Catarina I. Kiefe

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A family longevity selection score: ranking sibships by their longevity, size, and availability for study, Paola Sebastiani, Evan C. Hadley, Michael Province, Kaare Christensen, Winifred Rossi, Thomas T. Perls, and Arlene S. Ash

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Risk Adjustment of Outcomes, Michael Shwartz, Arlene S. Ash, and Lisa I. Iezzoni

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A controlled trial of value-based insurance design - the MHealthy: Focus on Diabetes (FOD) trial, Alicen Spaulding, A. Mark Fendrick, William H. Herman, James G. Stevenson, Dean G. Smith, Michael E. Chernew, Dawn M. Parsons, Keith Bruhnsen, and Allison B. Rosen

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Interatrial block: correlation with P-terminal force, David H. Spodick, Vignendra Ariyarajah, and Robert J. Goldberg

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Forecasting the effects of obesity and smoking on U.S. life expectancy, Susan T. Stewart, David M. Cutler, and Allison B. Rosen

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Traffic particles and occurrence of acute myocardial infarction: a case-control analysis, Cathryn Tonne, Jeffrey Yanosky, Alexandros Gryparis, Steven J. Melly, Murray A. Mittleman, Robert J. Goldberg, Stephanie von Klot, and Joel Schwartz

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Sex differences in mortality after acute myocardial infarction: changes from 1994 to 2006, Viola Vaccarino, Lori Parsons, Eric D. Peterson, William J. Rogers, Catarina I. Kiefe, and John Canto

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Elemental carbon exposure at residence and survival after acute myocardial infarction, Stephanie von Klot, Alexandros Gryparis, Cathryn Tonne, Jeffrey Yanosky, Brent A. Coull, Robert J. Goldberg, Darleen M. Lessard, Steven J. Melly, Helen H. Suh, and Joel Schwartz

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Incarceration, incident hypertension, and access to health care: findings from the coronary artery risk development in young adults (CARDIA) study, Emily A. Wang, Mark J. Pletcher, Feng Lin, Eric Vittinghoff, Stefan G. Kertesz, Catarina I. Kiefe, and Kirsten Bibbins-Domingo

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Documentation and management of overweight and obesity in primary care, Molly E. Waring, Mary B. Roberts, Donna R. Parker, and Charles B. Eaton

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Multidecade-long trends (1986-2005) in the utilization of coronary reperfusion and revascularization treatment strategies in patients hospitalized with acute myocardial infarction: a community-wide perspective, Jared Wasser, Robert J. Goldberg, Frederick A. Spencer, Jorge L. Yarzebski, and Joel M. Gore

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The importance of measuring competency-based outcomes: standard evaluation measures are not surrogates for clinical performance of internal medicine residents, Lisa L. Willett, Gustavo R. Heudebert, Katri P. Palonen, F. Stanford Massie, Catarina I. Kiefe, Jeroan J. Allison, Joshua Richman, and Thomas K. Houston

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Disentangling the influence of socioeconomic status on differences between African American and white women in unmet medical needs, Jacqueline C. Wiltshire, Sharina D. Person, Catarina I. Kiefe, and Jeroan J. Allison

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Full implementation of computerized physician order entry and medication-related quality outcomes: a study of 3364 hospitals, Feliciano B. Yu, Nir Menachemi, Eta S. Berner, Jeroan J. Allison, Thomas K. Houston, and Thomas K. Houston

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Pilot study of the characteristics of acute stroke events in patients discharged from the Carolina University Hospital, Puerto Rico in 2007, Juan Carlos Zevallos, Juan Gonzalez, Fernando Santiago, Rafael Rodriguez, Ada Rivera, Ana Michelle Garcia, Felixa Flecha, Marielys Colon, and Jorge L. Yarzebski

Publications from 2008

Identifying top-performing hospitals by algorithm: results from a demonstration project, Jeroan J. Allison, Norman W. Weissman, Andrea B. Silvey, Charlie A. Chapin, and Catarina I. Kiefe

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Measuring quality, Arlene S. Ash

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Florida 2006: Can Statistics Tell Us Who Won Congressional District-13?, Arlene S. Ash and John Lamperti

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Alterations on peripheral B cell subsets following an acute uncomplicated clinical malaria infection in children, Amolo S. Asito, Ann M. Moormann, Chelimo Kiprotich, Zipporah W. Ng'ang'a, Robert Ploutz-Snyder, and Rosemary A. Rochford

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Magnitude and prognosis associated with ventricular arrhythmias in patients hospitalized with acute coronary syndromes (from the GRACE Registry), Alvaro Avezum, Leopoldo S. Piegas, Robert J. Goldberg, David Brieger, Martin K. Stiles, Richard Paolini, Wei Huang, and Joel M. Gore

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Outpatient mastectomy and breast reconstructive surgery, John Bian, Helen Krontiras, and Jeroan J. Allison

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Impact of do-not-resuscitation orders on quality of care performance measures in patients hospitalized with acute heart failure, Joline L.T. Chen, Jonathan Sosnov, Darleen M. Lessard, and Robert J. Goldberg

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Effects of increased patient cost sharing on socioeconomic disparities in health care, Michael E. Chernew, Teresa B. Gibson, Kristina Yu-Isenberg, Michael C. Sokol, Allison B. Rosen, and A. Mark Fendrick

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Impact of decreasing copayments on medication adherence within a disease management environment, Michael E. Chernew, Mayur R. Shah, Arnold Wegh, Stephen N. Rosenberg, Iver A. Juster, Allison B. Rosen, Michael C. Sokol, Kristina Yu-Isenberg, and A. Mark Fendrick

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Implementing the community health worker model within diabetes management: challenges and lessons learned from programs across the United States, Andrea Cherrington, Guadalupe X. Ayala, Halle Amick, Jeroan J. Allison, Giselle Corbie-Smith, and Isabel Scarinci

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Applying the community health worker model to diabetes management: using mixed methods to assess implementation and effectiveness, Andrea Cherrington, Guadalupe X. Ayala, Halle Amick, Isabel Scarinci, Jeroan J. Allison, and Giselle Corbie-Smith

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Effect of racial differences on ability to afford prescription medications, Daniel J. Cobaugh, Erik Angner, Catarina I. Kiefe, Midge N. Ray, Cynthia L. LaCivita, Norman W. Weissman, Kenneth G. Saag, and Jeroan J. Allison

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Is the U.S. Population Behaving Healthier?, David M. Cutler, Edward L. Glaeser, and Allison B. Rosen

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Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults, Arlene E. Dent, Elke S. Bergmann-Leitner, Danny W. Wilson, Daniel J. Tisch, Rhonda Kimmel, John M. Vulule, Peter Odada Sumba, James G. Beeson, Evelina Angov, Ann M. Moormann, and James W. Kazura

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Comparison of 3 methods for identifying dietary patterns associated with risk of disease, Julia R. DiBello, Peter Kraft, Stephen T. McGarvey, Robert J. Goldberg, Hannia Campos, and Ana Baylin

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Therapies for acute heart failure in patients with reduced kidney function: a community-based perspective, Robert J. Goldberg, Rovshan M. Ismailov, Vishnu Patlolla, Darleen M. Lessard, and Frederick A. Spencer

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Long-term trends (1986-2003) in the use of coronary reperfusion strategies in patients hospitalized with acute myocardial infarction in central Massachusetts, Robert J. Goldberg, Frederick A. Spencer, Joseph Okolo, Darleen M. Lessard, Jorge L. Yarzebski, and Joel M. Gore

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Thirty-year trends (1975-2005) in the magnitude, patient characteristics, and hospital outcomes of patients with acute myocardial infarction complicated by ventricular fibrillation, Robert J. Goldberg, Jorge L. Yarzebski, Frederick A. Spencer, Juan Carlos Zevallos, Darleen M. Lessard, and Joel M. Gore

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Self-rated cardiovascular risk and 15-year cardiovascular mortality, Robert Gramling, William Klein, Mary B. Roberts, Molly E. Waring, David Gramling, and Charles B. Eaton

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Weighing in 10 Years Later: Reflections on Contagious Off-Label Use of Phentermine and Fenfluramine, Regina C. Grebla and Molly E. Waring

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The Demographic Assessment for Health Literacy (DAHL): a new tool for estimating associations between health literacy and outcomes in national surveys, Amresh D. Hanchate, Arlene S. Ash, Julie A. Gazmararian, Michael S. Wolf, and Michael K. Paasche-Orlow

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Exploring the determinants of racial and ethnic disparities in total knee arthroplasty: health insurance, income, and assets, Amresh D. Hanchate, Yuqing Zhang, David T. Felson, and Arlene S. Ash

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Does delayed measurement affect patient reports of provider performance? Implications for performance measurement of medical assistance with tobacco cessation: a Dental PBRN study, Thomas K. Houston, Joshua S. Richman, Heather L. Coley, Midge N. Ray, Jeroan J. Allison, Gregg H. Gilbert, Judith S. Gordon, and Catarina I. Kiefe

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Internet delivered support for tobacco control in dental practice: randomized controlled trial, Thomas K. Houston, Joshua S. Richman, Midge N. Ray, Jeroan J. Allison, Gregg H. Gilbert, Richard M. Shewchuk, Connie L. Kohler, and Catarina I. Kiefe

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Antibodies to pre-erythrocytic Plasmodium falciparum antigens and risk of clinical malaria in Kenyan children, Chandy C. John, Aaron J. Tande, Ann M. Moormann, Peter Odada Sumba, David E. Lanar, Xinan M. Min, and James W. Kazura

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Using the case mix of pressure ulcer healing to evaluate nursing home performance, Alok Kapoor, Boris Kader, Howard Cabral, Arlene S. Ash, and Dan R. Berlowitz

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Association of health-related quality of life with dual use of prescription and over-the-counter nonsteroidal antiinflammatory drugs, Stacey H. Kovac, Kenneth G. Saag, Jeffrey R. Curtis, and Jeroan J. Allison

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Can primary care visits reduce hospital utilization among Medicare beneficiaries at the end of life, Andrea C. Kronman, Arlene S. Ash, Karen M. Freund, Amresh Hanchate, and Ezekiel J. Emanuel

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Implications of comorbidity on costs for patients with Alzheimer disease, Tzu-Chun Kuo, Yang Zhao, Sharada G. Weir, Marilyn Schlein Kramer, and Arlene S. Ash

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Secondary analysis of merged American Hospital Association data and U.S. Census data: Beginning to understand the supply-demand chain in pediatric inpatient care, Susan R. Lacey, Meredith Kilgore, Huifeng Yun, Rhonda Hughes, Jeroan J. Allison, and Karen S. Cox

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Trends in the prevalence and mortality of cognitive impairment in the United States: is there evidence of a compression of cognitive morbidity, Kenneth M. Langa, Eric B. Larson, Jason H. Karlawish, David M. Cutler, Mohammed U. Kabeto, Scott Y. Kim, and Allison B. Rosen

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A mixed method study of the merits of e-prescribing drug alerts in primary care, Kate L. Lapane, Molly E. Waring, Karen L. Schneider, Catherine Dube, and Brian J. Quilliam

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Fine specificity of neonatal lymphocytes to an abundant malaria blood-stage antigen: epitope mapping of Plasmodium falciparum MSP1(33), Indu Malhotra, Alex N. Wamachi, Peter L. Mungai, Elton Mzungu, Davy Koech, Eric Muchiri, Ann M. Moormann, and Christopher L. King

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Percentage-Based versus Statistical-Power-Based Vote Tabulation Audits, John McCarthy, Howard Stanislevic, Mark Lindeman, Arlene S. Ash, Vittorio Addona, and Mary Batcher

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Residential exposure to traffic-related air pollution and survival after heart failure, Mercedes Medina-Ramón, Robert J. Goldberg, Steven J. Melly, Murray A. Mittleman, and Joel Schwartz

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Children with endemic Burkitt lymphoma are deficient in EBNA1-specific IFN-gamma T cell responses, Ann M. Moormann, Kevin N. Heller, Kiprotich Chelimo, Paula E. Embury, Robert Ploutz-Snyder, Juliana A. Otieno, Margaret Oduor, Christian Munz, and Rosemary A. Rochford

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Burkitt lymphoma in Uganda: 50 years of ongoing discovery, Ann M. Moormann and Jose S. Lozada

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Vertebroplasty and kyphoplasty are associated with an increased risk of secondary vertebral compression fractures: a population-based cohort study, Amy S. Mudano, John Bian, J. U. Cope, Jeffrey R. Curtis, T. P. Gross, Jeroan J. Allison, Y. Kim, D. Briggs, Mary Elkins-Melton, J. Xi, and Kenneth G. Saag

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Missed visits and mortality among patients establishing initial outpatient HIV treatment, Michael J. Mugavero, Hui-Yi Lin, James H. Willig, Andrew O. Westfall, Kimberly B. Ulett, Justin S. Routman, Sarah Abroms, James L. Raper, Michael S. Saag, and Jeroan J. Allison

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Immune escape by Epstein-Barr virus associated malignancies, Christian Munz and Ann M. Moormann

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A Web-based interactive Student Advising system using Java frameworks, V. R. Naini, Rajani S. Sadasivam, and Murat M. Tanik

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Racial differences in the competing risks of mortality and ESRD after acute myocardial infarction, Britt B. Newsome, William M. McClellan, Jeroan J. Allison, Paul W. Eggers, Shu-Cheng Chen, Allan J. Collins, Catarina I. Kiefe, Christopher S. Coffey, and David G. Warnock

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Long-term risk of mortality and end-stage renal disease among the elderly after small increases in serum creatinine level during hospitalization for acute myocardial infarction, Britt B. Newsome, David G. Warnock, William M. McClellan, Charles A. Herzog, Catarina I. Kiefe, Paul W. Eggers, and Jeroan J. Allison

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Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence in an area of stable malaria transmission, Gregory S. Noland, Brett Hendel-Paterson, Xinan M. Min, Ann M. Moormann, John M. Vulule, David L. Narum, David E. Lanar, James W. Kazura, and Chandy C. John

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Administrative codes combined with medical records based criteria accurately identified bacterial infections among rheumatoid arthritis patients, Nivedita M. Patkar, Jeffrey R. Curtis, Gim Gee Teng, Jeroan J. Allison, Michael S. Saag, Carolyn K. Martin, and Kenneth G. Saag

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Family environment is associated with endemic Burkitt lymphoma: a population-based case-control study, Jeanette J. Rainey, Rosemary A. Rochford, Peter Odada Sumba, Dickens Kowuor, Mark L. Wilson, and Ann M. Moormann

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Short-term discontinuation of HAART regimens more common in vulnerable patient populations, Lindsay S. Robison, Andrew O. Westfall, Michael J. Mugavero, Mirjam Kempf, Stephen R. Cole, Jeroan J. Allison, James H. Willig, James L. Raper, C. Mel Wilcox, and Michael S. Saag

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Evaluation of a preliminary physical function item bank supported the expected advantages of the Patient-Reported Outcomes Measurement Information System (PROMIS), M. Rose, Jakob B. Bjorner, J. Becker, J. F. Fries, and John E. Ware Jr.

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American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis, Kenneth G. Saag, Gim Gee Teng, Nivedita M. Patkar, Jeremy Anuntiyo, Catherine Finney, Jeffrey R. Curtis, Harold Paulus, Amy S. Mudano, Maria Pisu, Mary Elkins-Melton, Ryan Outman, Jeroan J. Allison, Maria Suarez Almazor, S. Louis Bridges Jr., W. Winn Chatham, Marc Hochberg, Catherine H. MacLean, Ted R. Mikuls, Larry W. Moreland, James O'Dell, Anthony M. Turkiewicz, and Daniel E. Furst

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Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik study, Jane S. Saczynski, Maria K. Jonsdottir, Melissa E. Garcia, Palmi V. Jonsson, Rita Peila, Gudny Eiriksdottir, Elin Olafsdottir, Tamara B. Harris, Vilmundur Gudnason, and Lenore J. Launer

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White matter lesions and cognitive performance: the role of cognitively complex leisure activity, Jane S. Saczynski, Maria K. Jonsdottir, Sigurdur Sigurdsson, Gudny Eiriksdottir, Palmi V. Jonsson, Melissa E. Garcia, Olafur Kjartansson, Mark A. van Buchem, Vilmundur Gudnason, and Lenore J. Launer

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An Architecture Framework for Process-Personalized Composite Services: Service-Oriented Architecture, Web Services, Business-Process Engineering, and Human Interaction Management, Rajani S. Sadasivam

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A conceptual framework for personalized mobile health care, Rajani S. Sadasivam, Murat M. Tanik, and James Willig

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Implementation Research: Beyond the Traditional Randomized Controlled Trial, Amanda H. Salanitro, Carlos A. Estrada, and Jeroan J. Allison

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Obesity Modifies the Association of Race/Ethnicity with Medication Adherence in the CARDIA Study, Maribel Salas, Catarina I. Kiefe, Pamela J. Schreiner, Yongin Kim, Lucia Juarez, Sharina D. Person, and O. Dale Williams

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Association of neighborhood socioeconomic status with physical fitness in healthy young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) study, Mehdi H. Shishehbor, Penny Gordon-Larsen, Catarina I. Kiefe, and David Litaker

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Patient outcomes after deep vein thrombosis and pulmonary embolism: the Worcester Venous Thromboembolism Study, Frederick A. Spencer, Joel M. Gore, Darleen M. Lessard, James D. Douketis, Cathy Emery, and Robert J. Goldberg

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The impact of symptoms and impairments on overall health in US national health data, Susan T. Stewart, Rebecca M. Woodward, Allison B. Rosen, and David M. Cutler

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SF-36® Health Survey, D. M. Turner-Bowker, M. A. DeRosa, and John E. Ware Jr.

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The therapeutic implications of timely linkage and early retention in HIV care, Kimberly B. Ulett, James H. Willig, Hui-Yi Lin, Justin S. Routman, Sarah Abroms, Jeroan J. Allison, Ashlee Chatham, James L. Raper, Michael S. Saag, and Michael J. Mugavero

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Improvements in short-form measures of health status: introduction to a series, John E. Ware Jr.

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Attention-deficit/hyperactivity disorder and obesity: moving to the next research generation, Molly E. Waring and Kate L. Lapane