Department of Quantitative Health Sciences
Medical Subject Headings
Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Male; Middle Aged; Neoplasms; Risk Factors
Bioinformatics | Biostatistics | Epidemiology | Health Services Research
In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.
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Citation: Clin Infect Dis. 2004 Nov 1;39(9):1380-4. Epub 2004 Oct 11. © 2004 by the Infectious Diseases Society of America. Link to article on publisher's site
Bedimo, Roger; Chen, Ray Y.; Accortt, Neil A.; Raper, James L.; Linn, Carol; Allison, Jeroan J.; Dubay, John; Saag, Michael S.; and Hoesley, Craig J., "Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002" (2004). Quantitative Health Sciences Publications and Presentations. 792.