Endemic Burkitt's lymphoma: a polymicrobial disease

UMMS Affiliation

Department of Quantitative Health Sciences; Department of Pediatrics



Document Type


Medical Subject Headings

Animals; B-Lymphocytes; Burkitt Lymphoma; Dendritic Cells; *Endemic Diseases; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Malaria, Falciparum; Plasmodium falciparum


Biostatistics | Epidemiology | Health Services Research | Immunology and Infectious Disease | Pediatrics


Endemic Burkitt's lymphoma is the most common childhood cancer in equatorial Africa. Two ubiquitous human pathogens are thought to be responsible for the aetiology of this disease: Epstein-Barr virus and Plasmodium falciparum malaria. New data suggest how these two pathogens might interact to result in disease and provide insights into the emerging concepts of polymicrobial disease pathogenesis.

Rights and Permissions

Citation: Nat Rev Microbiol. 2005 Feb;3(2):182-7. Link to article on publisher's site

Related Resources

Link to Article in PubMed