Prepregnancy depressive mood and preterm birth in black and white women: findings from the CARDIA Study
UMass Chan Affiliations
Department of Quantitative Health SciencesDocument Type
Journal ArticlePublication Date
2009-05-19Keywords
AdultAfrican Continental Ancestry Group
Comorbidity
Depression
European Continental Ancestry Group
Female
*Health Status
Humans
Infant, Newborn
Multivariate Analysis
Obstetric Labor, Premature
Odds Ratio
Pregnancy
Pregnancy Outcome
Prenatal Care
Risk Factors
Young Adult
Bioinformatics
Biostatistics
Epidemiology
Health Services Research
Metadata
Show full item recordAbstract
OBJECTIVES: We examine associations among race, prepregnancy depressive mood, and preterm birth (<37 weeks gestation) in a cohort study of black and white women. METHODS: We tested for mediation of the association between race and preterm birth by prepregnancy depressive mood among 555 women enrolled in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. RESULTS: Black women had significantly higher levels of prepregnancy depressive mood (modified CES-D score 13.0 vs. 9.5, t = -4.64, p < 0.001). After adjustment for covariates, black women had 2.70 times the odds of preterm birth as white women (95% confidence interval [CI] 1.41, 5.17). When adding prepregnancy depressive mood to this model, higher depressive mood was associated with greater odds of preterm birth (odds ratio [OR] 1.04; 95% CI 1.01, 1.07), and the effect of black race was attenuated (OR 2.47, 95% CI 1.28, 4.77). CONCLUSIONS: Our data suggest that prepregnancy depressive mood may be a risk factor for preterm birth among black and white women.Source
J Womens Health (Larchmt). 2009 Jun;18(6):803-11. Link to article on publisher's siteDOI
10.1089/jwh.2008.0984Permanent Link to this Item
http://hdl.handle.net/20.500.14038/47052PubMed ID
19445645Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1089/jwh.2008.0984