Title

Coronary artery status of apparently healthy subjects with frequent and complex ventricular ectopy

UMMS Affiliation

Department of Medicine, Division of Cardiovascular Medicine

Date

2-1-1980

Document Type

Article

Medical Subject Headings

Adult; Aged; Arrhythmias, Cardiac; Coronary Angiography; Coronary Disease; Electrocardiography; Female; Heart; Heart Function Tests; Heart Ventricles; Humans; Male; Middle Aged; Physical Exertion

Disciplines

Bioinformatics | Biostatistics | Epidemiology | Health Services Research

Abstract

Twenty-five subjects from a cohort of 62 asymptomatic, apparently healthy subjects incidentally discovered to have frequent and complex ventricular ectopy were studied with cardiac catheterization and coronary angiography. Fourteen had normal coronary arteries, five noncritical coronary artery disease (less than 50% luminal narrowing), and six significant coronary artery disease (greater than or equal to 50% luminal narrowing). Slightly elevated left ventricular end diastolic pressures were found in all subject subgroups. Characteristics of the ventricular ectopy detected by maximal exercise testing or 24-hour Holter ambulatory electrocardiography did not differentiate those subjects with coronary artery disease from those with normal coronary arteries. This study documents that a minority of apparently healthy subjects with frequent and complex ventricular arrhythmia have significant coronary artery disease and supports a conservative approach to the management of such patients.

Rights and Permissions

Citation: Ann Intern Med. 1980 Feb;92(2 Pt 1):179-85.

Related Resources

Link to Article in PubMed