Incorporating severity of illness into estimates of likelihood ratios

UMMS Affiliation

Department of Quantitative Health Sciences

Publication Date


Document Type



Alcohol Drinking; Alcoholism; *Erythrocyte Indices; Humans; Male; Middle Aged; Probability


Bioinformatics | Biostatistics | Epidemiology | Health Services Research


Although severity of illness may affect the usefulness of a diagnostic test, most previous work has considered test performance only in the dichotomous situation where the target disorder is considered present or absent. In this paper, a clinical example is provided and two methods presented whereby illness severity may be incorporated into the determination of likelihood ratios for a diagnostic test. The use of this approach is that given a test result, a clinician may determine the post-test probability of all levels of the illness in the patient under study.

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Citation: Am J Med Sci. 1990 Jan;299(1):38-42.

Journal/Book/Conference Title

The American journal of the medical sciences

PubMed ID


Related Resources

Link to Article in PubMed