Comparison of outcomes research with clinical trials using preexisting data
Department of Quantitative Health Sciences
Medical Subject Headings
Bias (Epidemiology); *Cardiology; Causality; Cohort Studies; Confounding Factors (Epidemiology); Data Collection; *Databases, Factual; Ethics, Medical; *Health Services Research; Humans; *Outcome Assessment (Health Care); *Randomized Controlled Trials as Topic; Research Design
Bioinformatics | Biostatistics | Epidemiology | Health Services Research
Outcomes research using analysis of preexisting data is a relatively new field with the potential to improve the quality and effectiveness of medical care, and may provide a useful complement to randomized studies. Motivated by the growth of this research in the cardiovascular literature, this review offers a framework to identify the core concepts of outcomes research from database analyses by comparing and contrasting it with the randomized clinical trial.
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Citation: Am J Cardiol. 1999 Oct 15;84(8):923-7, A6.
Canto, John G.; Kiefe, Catarina I.; Williams, O. Dale; Barron, Hal V.; and Rogers, William J., "Comparison of outcomes research with clinical trials using preexisting data" (1999). Quantitative Health Sciences Publications and Presentations. 131.