IROC Rhode Island (QARC) Publications

Title

Image based feasibility of renal sparing surgery for very low risk unilateral Wilms tumors: a report from the Children's Oncology Group

UMMS Affiliation

Quality Assurance Review Center

Date

11-1-2013

Document Type

Article

Disciplines

Health Services Administration | Neoplasms | Oncology | Pediatrics | Radiology | Urology

Abstract

PURPOSE: Nephrectomy with lymph node sampling is the recommended treatment for children with unilateral Wilms tumor under the Children's Oncology Group protocols. Using radiological assessment, we determined the feasibility of performing partial nephrectomy in a select group of patients with very low risk unilateral Wilms tumor.

MATERIALS AND METHODS: We reviewed imaging studies of 60 patients with a mean age of less than 2 years with very low risk unilateral Wilms tumor (mean weight less than 550 gm) to assess the feasibility of partial nephrectomy. We evaluated percentage of salvageable parenchyma, tumor location and anatomical features preventing a nephron sparing approach.

RESULTS: A linear relationship exists between tumor weight and computerized tomography estimated tumor volume. Mean tumor weight in the study population was 315 gm. Partial nephrectomy was deemed feasible in only 5 of 60 patients (8%).

CONCLUSIONS: When considering a select population with very low risk unilateral Wilms tumor (lower volume tumor), only a small percentage of nonpretreated patients are candidates for nephron sparing surgery. .

Rights and Permissions

Citation: J Urol. 2013 Nov;190(5):1846-51. doi: 10.1016/j.juro.2013.05.060. Epub 2013 May 30. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

23727411