The NIH Toolbox Cognition Battery: results from a large normative developmental sample (PING)
Authors
Akshoomoff, NatachaNewman, Erik
Thompson, Wesley K.
McCabe, Connor
Bloss, Cinnamon S.
Chang, Linda
Amaral, David G.
Casey, B. J.
Ernst, Thomas M.
Frazier, Jean A.
Gruen, Jeffrey R.
Kaufmann, Walter E.
Kenet, Tal
Kennedy, David N.
Libiger, Ondrej
Mostofsky, Stewart
Murray, Sarah S.
Sowell, Elizabeth R.
Schork, Nicholas J.
Dale, Anders M.
Jernigan, Terry L.
UMass Chan Affiliations
Intellectual and Developmental Disabilities Research CenterDepartment of Psychiatry
Document Type
Journal ArticlePublication Date
2014-01-01Keywords
Cognitive PsychologyMental and Social Health
Neuroscience and Neurobiology
Pediatrics
Psychiatry
Psychiatry and Psychology
Metadata
Show full item recordAbstract
OBJECTIVE: The NIH Toolbox Cognition Battery (NTCB) was designed to provide a brief, efficient computerized test of key neuropsychological functions appropriate for use in children as young as 3 years of age. This report describes the performance of a large group of typically developing children and adolescents and examines the impact of age and sociocultural variables on test performance. METHOD: The NTCB was administered to a sample of 1,020 typically developing males and females ranging in age from 3 to 20 years, diverse in terms of socioeconomic status (SES) and race/ethnicity, as part of the new publicly accessible Pediatric Imaging, Neurocognition, and Genetics (PING) data resource, at 9 sites across the United States. RESULTS: General additive models of nonlinear age-functions were estimated from age-differences in test performance on the 8 NTCB subtests while controlling for family SES and genetic ancestry factors (GAFs). Age accounted for the majority of the variance across all NTCB scores, with additional significant contributions of gender on some measures, and of SES and race/ethnicity (GAFs) on all. After adjusting for age and gender, SES and GAFs explained a substantial proportion of the remaining unexplained variance in Picture Vocabulary scores. CONCLUSIONS: The results highlight the sensitivity to developmental effects and efficiency of this new computerized assessment battery for neurodevelopmental research. Limitations are observed in the form of some ceiling effects in older children, some floor effects, particularly on executive function tests in the youngest participants, and evidence for variable measurement sensitivity to cultural/socioeconomic factors.Source
NAkshoomoff N, Newman E, Thompson WK, McCabe C, Bloss CS, Chang L, Amaral DG, Casey BJ, Ernst TM, Frazier JA, Gruen JR, Kaufmann WE, Kenet T, Kennedy DN, Libiger O, Mostofsky S, Murray SS, Sowell ER, Schork N, Dale AM, Jernigan TL. The NIH Toolbox Cognition Battery: results from a large normative developmental sample (PING). Neuropsychology. 2014 Jan;28(1):1-10. doi: 10.1037/neu0000001. Epub 2013 Nov 11. Erratum in: Neuropsychology. 2014 Mar;28(2):319. PubMed PMID: 24219608; PubMed Central PMCID: PMC3925365. Link to article on publisher's siteDOI
10.1037/neu0000001Permanent Link to this Item
http://hdl.handle.net/20.500.14038/46167PubMed ID
24219608Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1037/neu0000001