Three-dimensional source imaging from simultaneously recorded ERP and BOLD-fMRI
Department of Psychiatry
Medical Subject Headings
Adult; Artifacts; Data Interpretation, Statistical; Electroencephalography; Evoked Potentials; Evoked Potentials, Visual; Humans; *Image Processing, Computer-Assisted; *Imaging, Three-Dimensional; Least-Squares Analysis; Magnetic Resonance Imaging; Male; Oxygen; Photic Stimulation; Young Adult
We present the 3-D EEG source images reconstructed by using the minimum norm least square (MNLS) method in combination with the functional magnetic resonance imaging (fMRI) statistical parametric mapping. For a group of five normal subjects, electroencephalogram (EEG) and fMRI signals responding to the full-view checkerboard pattern-reversal visual stimulation were recorded simultaneously and separately. The electrical activities in V1/V2 and V5 were successfully imaged in the N75-P100-N145 and P100-N145 components, respectively. The present results demonstrate the merits of high-resolution spatiotemporal functional neuroimaging by integrating the simultaneously recorded fMRI and EEG data.
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Citation: IEEE Trans Neural Syst Rehabil Eng. 2009 Apr;17(2):101-6. Epub 2009 Feb 18. Link to article on publisher's site