Title

Mania after withdrawal of isocarboxazid

UMMS Affiliation

Department of Psychiatry

Date

12-1-1985

Document Type

Article

Medical Subject Headings

Adult; Bipolar Disorder; Dopamine; Female; Humans; Isocarboxazid; Male; *Substance Withdrawal Syndrome

Disciplines

Psychiatry

Abstract

Two cases of mania following the discontinuation of treatment with isocarboxazid are described. Although this phenomenon has been reported by several investigators to occur after cessation of tricyclic antidepressant therapy, there exists only one isolated report of hypomania after discontinuation of monoamine oxidase inhibitors. Possible mechanisms for the occurrence of hypomania and mania after withdrawal from antidepressants are discussed.

Rights and Permissions

Citation: J Clin Psychopharmacol. 1985 Dec;5(6):340-2.

Related Resources

Link to Article in PubMed

PubMed ID

4067000