Title

Effects of clozapine on smoking in chronic schizophrenic outpatients

UMMS Affiliation

Department of Psychiatry

Date

8-1-1995

Document Type

Article

Medical Subject Headings

Adult; *Ambulatory Care; Antipsychotic Agents; Chronic Disease; Clozapine; Coffee; Drinking; Female; Humans; Male; Middle Aged; Pilot Projects; Prevalence; Psychiatric Status Rating Scales; Psychotic Disorders; Retrospective Studies; Schizophrenia; Smoking; Smoking Cessation

Disciplines

Psychiatry

Abstract

BACKGROUND: The effects of clozapine administration on smoking were examined in chronic schizophrenic outpatients.

METHOD: Twenty-nine of 30 schizophrenic outpatients enrolled in a university-affiliated Community Mental Health Center clozapine clinic were retrospectively surveyed by semistructured questionnaire regarding smoking before and after clozapine administration.

RESULTS: Smokers comprised 62% (N = 18) of patients, and within this group, there was a significant decrease in reported daily cigarette use during clozapine treatment compared with level of use when patients had been treated with typical neuroleptics (1.67 +/- 1.13 vs. 1.26 +/- 0.72 packs/day, p = .025).

CONCLUSION: Clozapine may alter smoking behaviors in chronic schizophrenics.

Rights and Permissions

Citation: J Clin Psychiatry. 1995 Aug;56(8):344-6.

Related Resources

Link to Article in PubMed

PubMed ID

7635849

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