Clinical features of chinese coronary heart disease patients with chronic kidney disease
UMass Chan Affiliations
Department of Medicine, Division of Preventive and Behavioral MedicineDocument Type
Journal ArticlePublication Date
2012-08-01Keywords
Coronary DiseaseKidney Diseases
China
Behavioral Disciplines and Activities
Behavior and Behavior Mechanisms
Cardiovascular Diseases
Community Health and Preventive Medicine
Female Urogenital Diseases and Pregnancy Complications
Male Urogenital Diseases
Preventive Medicine
Metadata
Show full item recordAbstract
Objectives: To investigate the prevalence of chronic kidney disease (CKD) by stage in Chinese patients with coronary heart disease (CHD) and to identify the clinical features and examine control of cardiovascular risk factors. Methods and results: Clinical data of hospitalized patients were collected by investigators in China. CKD stages were classified according to estimated glomerular filtration rate (eGFR). A total of 2509 participants with CHD were included in the final statistical analysis. The overall prevalence of CKD stage 3 and greater (eGFR of less than 60 mL/min/1.73 m(2)) in the CHD patients was 32.5%. As the CKD stage increased, fasting blood glucose (FBG), systolic blood pressure (SBP), diastolic blood pressure (DBP), and high-sensitivity C-reactive protein (HS-CRP) levels all worsened. As the CKD stage became more severe, CHD patients had comorbidities such as diabetes mellitus, periphery arterial disease, and ischemic stroke, and more CHD patients had triple vessel disease increased. Even when patients received treatment of CHD and risk factors, control of cardiovascular risk factors such as SBP, DBP, FBG, and low-density lipoprotein was worsened as CKD stage became more severe over a 6-week follow-up. Conclusions: The data suggested a high prevalence of CKD in Chinese patients with CHD. Many conventional risk factors and comorbidities were correlated with high prevalence of CKD in CHD patients. Control of cardiovascular risk factors in those patients was poor.Source
Yong Wang, Dongdong Zhao, Yan Xing, Jue Li, Dayi Hu, Yawei Xu, Philip A. Merriam, and Yunsheng Ma. 2012. Clinical Features of Chinese Coronary Heart Disease Patients with Chronic Kidney Disease. Renal Failure, 34(8):985-990. doi: 10.3109/0886022X.2012.706879DOI
10.3109/0886022X.2012.706879Permanent Link to this Item
http://hdl.handle.net/20.500.14038/44805Related Resources
Link to article in PubMedae974a485f413a2113503eed53cd6c53
10.3109/0886022X.2012.706879
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