Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease
Authors
Ma, YunshengOckene, Ira S.
Rosal, Milagros C.
Merriam, Philip A.
Ockene, Judith K.
Gandhi, Pritesh J.
UMass Chan Affiliations
Department of Medicine, Division of Cardiovascular MedicineDepartment of Medicine, Division of Preventive and Behavioral Medicine
Document Type
Journal ArticlePublication Date
2010-06-21Keywords
Coronary DiseaseIntervention Studies
Pharmacists
Patient Compliance
Medication Adherence
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Behavioral Disciplines and Activities
Behavior and Behavior Mechanisms
Cardiovascular Diseases
Community Health and Preventive Medicine
Preventive Medicine
Metadata
Show full item recordAbstract
A randomized trial of a pharmacist-delivered intervention (PI) versus usual care (UC) was conducted; 689 subjects with known coronary heart disease were recruited from cardiac catheterization laboratories. Participants in the PI condition received 5 pharmacist-delivered telephone counseling calls post-hospital discharge. At one year, 65% in the PI condition and 60% in the UC condition achieved an LDL-C level <100 mg/dL (P=.29); mean statin adherence was 0.88 in the PI, and 0.90 in the UC (P=.51). The highest percentage of those who reached the LDL-C goal were participants who used statins as opposed to those who did not use statins (67% versus 58%, P=.05). However, only 53% and 56% of the patients in the UC and PI conditions, respectively, were using statins. We conclude that a pharmacist-delivered intervention aimed only at improving patient adherence is unlikely to positively affect outcomes. Efforts must be oriented towards influencing physicians to increase statin prescription rates.Source
Yunsheng Ma, Ira S. Ockene, Milagros C. Rosal, Philip A. Merriam, Judith K. Ockene, and Pritesh J. Gandhi, “Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease,” Cholesterol, vol. 2010, Article ID 383281, 11 pages, 2010. doi:10.1155/2010/383281 Link to article on publisher's websiteDOI
10.1155/2010/383281Permanent Link to this Item
http://hdl.handle.net/20.500.14038/44707Rights
Copyright © 2010 Yunsheng Ma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.ae974a485f413a2113503eed53cd6c53
10.1155/2010/383281