The Program in Molecular Medicine at the University of Massachusetts Medical School was established in a new research building in 1989. Molecular Medicine is characterized by a diverse faculty of both basic biomedical scientists and physician-scientists. The program’s strategy for scientific development has been to assemble outstanding investigators with overlapping scientific interests who apply their unique knowledge to molecular mechanisms that underlie physiological processes and associated diseases. Areas of expertise include chemistry; structural biology; biochemistry; cell, developmental and molecular biology; cell signaling and regulation; genomics and proteomics; genetics; and immunology and virology. Molecular Medicine faculty are active in teaching these disciplines in both core and advanced courses to graduate and medical students.