eScholarship@UMMS

Title

ER stress as a trigger for beta-cell dysfunction and autoimmunity in type 1 diabetes

Authors

Bryan M. O'Sullivan-Murphy, University of Massachusetts Medical SchoolFollow
Fumihiko Urano, University of Massachusetts Medical SchoolFollow

UMMS Affiliation

Program in Gene Function and Expression; Program in Molecular Medicine

Date

4-1-2012

Document Type

Response or Comment

Medical Subject Headings

Animals; Diabetes Mellitus, Type 1; Endoplasmic Reticulum; Female; Insulin-Secreting Cells; Stress, Physiological

Disciplines

Endocrine System Diseases | Genetics and Genomics | Immunology and Infectious Disease

Abstract

Comment on: Tersey SA, Nishiki Y, Templin AT, Cabrera SM, Stull ND, Colvin SC, Evans-Molina C, Rickus JL, Maier B, Mirmira RG. Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes. 2012 Apr;61(4):818-27.

Comments

Citation: Diabetes. 2012 Apr;61(4):780-1. Link to article on publisher's site

© 2012 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

Related Resources

Link to Article in PubMed