UMMS Affiliation

Program in Gene Function and Expression; Program in Systems Biology; Department of Biochemistry and Molecular Pharmacology



Document Type


Medical Subject Headings

Repressor Proteins; DNA-Binding Proteins; Chromosomal Proteins, Non-Histone; Neurons; Gene Expression Regulation


Genetics and Genomics


In the brain neurons form extensively intermingled projections and synaptic interactions between them. To achieve proper neural connectivity, interactions between sections belonging to the same neuron are avoided. However, how can a cell tell, when it encounters another neuronal projection, whether it is part of the same cell? In other words, how do neurons become self-aware?


Citation: Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8799-800. Epub 2012 May 21. Link to article on publisher's site

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Related Resources

Link to Article in PubMed

PubMed ID




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