UMMS Affiliation
Program in Gene Function and Expression; Program in Systems Biology; Department of Biochemistry and Molecular Pharmacology
Date
6-5-2012
Document Type
Article
Medical Subject Headings
Repressor Proteins; DNA-Binding Proteins; Chromosomal Proteins, Non-Histone; Neurons; Gene Expression Regulation
Disciplines
Genetics and Genomics
Abstract
In the brain neurons form extensively intermingled projections and synaptic interactions between them. To achieve proper neural connectivity, interactions between sections belonging to the same neuron are avoided. However, how can a cell tell, when it encounters another neuronal projection, whether it is part of the same cell? In other words, how do neurons become self-aware?
Comments
Citation: Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8799-800. Epub 2012 May 21. Link to article on publisher's site
Publisher PDF posted as allowed by the publisher's author rights policy at http://www.pnas.org/site/misc/authorfaq.shtml.