Effects of a multicomponent wellness intervention on dyslipidemia among overweight adolescents

UMMS Affiliation

Department of Pediatrics



Document Type


Medical Subject Headings

Adolescent; Body Mass Index; Cholesterol, HDL; Dyslipidemias; *Exercise; Female; Humans; Male; Nutritional Physiological Phenomena; Overweight; *Patient Education as Topic


Behavior and Behavior Mechanisms | Endocrinology, Diabetes, and Metabolism | Pediatrics


Behavioral changes are the first line of treatment for dyslipidemia in adolescents, but outcome data on the effectiveness of this approach are inconsistent. This study aims to assess the effect of a 13-week multicomponent wellness intervention program, which included weekly nutrition classes and structured cardiovascular, flexibility, and strength training on dyslipidemia in nine overweight/obese [body mass index (BMI) > or = 85th percentile] and nine lean (BMIpercentile) adolescents. Clinical measurements and lipid profile assessment were performed before and after the intervention. At the completion of the study, the overweight/obese adolescents demonstrated a 15% increase in high-density lipoprotein cholesterol (HDL-C) levels (mean, 47 +/- 8 vs. 54 +/- 5 mg/dL), whereas there was no improvement in BMI or other measurements. The participants in the lean group showed no change in their anthropometric and serum parameters. A multicomponent wellness intervention resulted in a significant increase of cardioprotective HDL-C levels, which have been associated with coronary health in adulthood.

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Citation: J Pediatr Endocrinol Metab. 2012;25(1-2):79-82. DOI 10.1515/jpem.2011.386

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