Title
Absence of hippocampal sclerosis in children with multiple daily seizures since infancy
UMMS Affiliation
Department of Pediatrics; Department of Pathology
Date
8-2001
Document Type
Article
Medical Subject Headings
Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Humans; Infant; Magnetic Resonance Imaging; Neurosurgical Procedures; Periodicity; Retrospective Studies; Sclerosis; Temporal Lobe
Disciplines
Neurology | Pathology | Pediatrics
Abstract
We report a series of nine children with multiple daily seizures since infancy who underwent functional hemispherectomy that included en bloc resection of the hippocampus and the temporal neocortex. In all cases, the hippocampi were normal by conventional histology despite the fact that these patients had suffered from recurrent seizures over a long period of time. This observation suggests that extremely frequent seizures in childhood are not invariably associated with the development of hippocampal sclerosis.
Rights and Permissions
Citation: J Child Neurol. 2001 Aug;16(8):562-4. doi: 10.1177/088307380101600804