This collection showcases the journal articles and other publications authored by faculty and researchers in the Division of Immunology/Infectious Disease in the Department of Pediatrics at the University of Massachusetts Medical School.

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Publications from 2014

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Sickle cell trait is not associated with endemic Burkitt lymphoma: an ethnicity and malaria endemicity-matched case-control study suggests factors controlling EBV may serve as a predictive biomarker for this pediatric cancer, David H. Mulama, Jeffrey A. Bailey, Joslyn Foley, Kiprotich Chelimo, Collins Ouma, Walter G.Z.O. Jura, Juliana A. Otieno, John M. Vulule, and Ann M. Moormann

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Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic burkitt lymphoma, Cliff I. Oduor, Kiprotich Chelimo, Collins Ouma, David H. Mulama, Joslyn Foley, John M. Vulule, Jeffrey A. Bailey, and Ann M. Moormann

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Decreased Growth Rate of P. falciparum Blood Stage Parasitemia With Age in a Holoendemic Population, Mykola Pinkevych, Janka Petravic, Kiprotich Chelimo, John M. Vulule, James W. Kazura, Ann M. Moormann, and Miles P. Davenport

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Epstein-barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluids, Nicholas Renzette, Mohan Somasundaran, Frank E. Brewster, James Coderre, Eric R. Weiss, Margaret M. McManus, Thomas C. Greenough, Barbara Tabak, Manuel Garber, Timothy F. Kowalik, and Katherine Ruiz De Luzuriaga

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Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study, Steve M. Taylor, Derrick K. DeConti, Ann M. Moormann, Jeffrey A. Bailey, and Jonathan J. Juliano

Publications from 2013

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Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain, Markus-Frederik Bohn, Shivender M. D. Shandilya, John S. Albin, Takahide Kouno, Brett D. Anderson, Rebecca M. McDougle, Michael A. Carpenter, Anurag Rathore, Leah Evans, Ahkillah N. Davis, JingYing Zhang, Yongjian Lu, Mohan Somasundaran, Hiroshi Matsuo, Reuben S. Harris, and Celia A. Schiffer

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Factors influencing time to diagnosis and initiation of treatment of endemic Burkitt Lymphoma among children in Uganda and western Kenya: a cross-sectional survey, Geoffrey C. Buckle, Jennifer Pfau Collins, Peter Odada Sumba, Beccy Nakalema, Dorine Omenah, Kristine Stiffler, Corey Casper, Juliana A. Otieno, Jackson Orem, and Ann M. Moormann

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Mentoring future Kenyan oncology researchers, Ann M. Moormann, Jodi Skiles, Emmanuel Koros, Fredrick Chite Asirwa, Naftali Busakhala, and Patrick Loehrer

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Humoral and Cellular Immunity to Plasmodium falciparum Merozoite Surface Protein 1 and Protection from Blood-stage Infection, Ann M. Moormann, Peter Odada Sumba, Kiprotich Chelimo, Hua Fang, Daniel J. Tisch, Arlene E. Dent, Chandy C. John, Carole A. Long, John Vulule, and James W. Kazura

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Absence of detectable HIV-1 viremia after treatment cessation in an infant, Deborah Persaud, Hannah Gay, Carrie Ziemniak, Ya Hui Chen, Michael Piatak Jr., Tae-Wook Chun, Matthew Strain, Douglas Richman, and Katherine Ruiz De Luzuriaga

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Density-dependent blood stage Plasmodium falciparum suppresses malaria super-infection in a malaria holoendemic population, Mykola Pinkevych, Janka Petravic, Kiprotich Chelimo, John M. Vulule, James W. Kazura, Ann M. Moormann, and Miles P. Davenport

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Rapid intrahost evolution of human cytomegalovirus is shaped by demography and positive selection, Nicholas Renzette, Laura L. Gibson, Bornali Bhattacharjee, Donna Fisher, Mark R. Schleiss, Jeffrey D. Jensen, and Timothy F. Kowalik

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Identification of a novel variant of LMP-1 of EBV in patients with endemic Burkitt lymphoma in western Kenya, Eric M. Wohlford, Amolo S. Asito, Kiprotich Chelimo, Peter Odada Sumba, Paul C. Baresel, Rebecca A. Oot, Ann M. Moormann, and Rosemary A. Rochford

Publications from 2012

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Mass spectrometry tools for analysis of intermolecular interactions, Jared R. Auclair, Mohan Somasundaran, Karin M. Green, James E. Evans, Celia A. Schiffer, Dagmar Ringe, Gregory A. Petsko, and Jeffrey N. Agar

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Broadly reactive antibodies specific for Plasmodium falciparum MSP-119 are associated with the protection of naturally exposed children against infection, Arlene E. Dent, Ann M. Moormann, Christopher T. Yohn, Rhonda J. Kimmel, Peter Odada Sumba, John Vulule, Carole A. Long, David L. Narum, Brendan S. Crabb, James W. Kazura, and Daniel J. Tisch

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First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G, Ming Li, Shivender Shandilya, Michael A. Carpenter, Anurag Rathore, William L. Brown, Angela L. Perkins, Daniel A. Harki, Jonathan Solberg, Derek J. Hook, Krishan K. Pandey, Michael A. Parniak, Jeffrey R. Johnson, Nevan J. Krogan, Mohan Somasundaran, Akbar Ali, Celia A. Schiffer, and Reuben S. Harris

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Human CD4+ T cell response to human herpesvirus 6, Maria-Dorothea Nastke, Aniuska Becerra, Liusong Yin, Omar Dominguez-Amorocho, Laura L. Gibson, Lawrence J. Stern, and J. Mauricio Calvo-Calle

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Dynamics of the resting CD4(+) T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age, Deborah Persaud, Paul E. Palumbo, Carrie Ziemniak, Michael D. Hughes, Carmelita G. Alvero, Katherine Luzuriaga, Ram Yogev, Edmund V. Capparelli, and Ellen Gould Chadwick

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The Dynamics of Naturally Acquired Immunity to Plasmodium falciparum Infection, Mykola Pinkevych, Janka Petravic, Kiprotich Chelimo, James W. Kazura, Ann M. Moormann, and Miles P. Davenport

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Early age at time of primary Epstein-Barr virus infection results in poorly controlled viral infection in infants from Western Kenya: clues to the etiology of endemic Burkitt lymphoma, Erwan Piriou, Amolo S. Asito, Peter Odada Sumba, Nancy Fiore, Jaap M. Middeldorp, Ann M. Moormann, Robert Ploutz-Snyder, and Rosemary A. Rochford

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Recurrent Plasmodium falciparum malaria infections in Kenyan children diminish T-cell immunity to Epstein Barr virus lytic but not latent antigens, Cynthia J. Snider, Stephen R. Cole, Kiprotich Chelimo, Peter Odada Sumba, Pia D. M. Macdonald, Chandy C. John, Steven R. Meshnick, and Ann M. Moormann

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Persistence of epstein-barr virus in self-reactive memory B cells, Sean I. Tracy, Kristina Kakalacheva, Jan D. Lunemann, Katherine Luzuriaga, Jaap M. Middeldorp, and David A. Thorley-Lawson

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Pilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates, Shixia Wang, Michael G. Kishko, Shengqin Wan, Yan Wang, Frank E. Brewster, Glenda E. Gray, Avye Violari, John L. Sullivan, Mohan Somasundaran, Katherine Luzuriaga, and Shan Lu

Publications from 2011

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Genotypic and functional properties of early infant HIV-1 envelopes, Michael G. Kishko, Mohan Somasundaran, Frank E. Brewster, John L. Sullivan, Paul R. Clapham, and Katherine Luzuriaga

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A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection, Thomas A. Musich, Paul J. Peters, Maria J. Duenas-Decamp, Maria Paz Gonzalez-Perez, James E. Robinson, Susan Zolla-Pazner, Jonathan K. Ball, Katherine Luzuriaga, and Paul R. Clapham

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Effect of therapeutic HIV recombinant poxvirus vaccines on the size of the resting CD4+ T-cell latent HIV reservoir, Deborah Persaud, Katherine Luzuriaga, Carrie Ziemniak, Petronella Muresan, Thomas Greenough, Terry Fenton, Amanda Blackford, Kimberly Ferguson, Natalie Neu, and Coleen K. Cunningham

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Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants, Nicholas Renzette, Bornali Bhattacharjee, Jeffrey D. Jensen, Laura L. Gibson, and Timothy F. Kowalik

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Efficacy model for antibody-mediated pre-erythrocytic malaria vaccines, Michael T. White, Jamie T. Griffin, Eleanor M. Riley, Chris J. Drakeley, Ann M. Moormann, Peter Odada Sumba, James W. Kazura, Azra C. Ghani, and Chandy C. John

Publications from 2010

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Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes, Shalyn Catherine Clute, Yuri N. Naumov, Levi B. Watkin, Nuray Aslan, John L. Sullivan, David A. Thorley-Lawson, Katherine Luzuriaga, Raymond M. Welsh, Roberto Puzone, Franco Celada, and Liisa K. Selin

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Programmed Death-1 expression on Epstein Barr virus specific CD8+ T cells varies by stage of infection, epitope specificity, and T-cell receptor usage, Thomas C. Greenough, Shalyn C. Campellone, Robin M. Brody, Surbhi Jain, Victor Sanchez-Merino, Mohan Somasundaran, and Katherine Luzuriaga

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Treatment with monoclonal antibodies against Clostridium difficile toxins, Israel Lowy, Deborah C. Molrine, Brett A. Leav, Barbara M. Blair, Roger Baxter, Dale N. Gerding, Geoffrey Nichol, William D. Thomas, Mark Leney, Susan Sloan, Catherine A. Hay, and Donna M. Ambrosino

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Infectious mononucleosis, Katherine Luzuriaga and John L. Sullivan

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Impaired generation of hepatitis B virus-specific memory B cells in HIV infected individuals following vaccination, Nishaki Mehta, Coleen K. Cunningham, Patricia Flynn, Joyce A. Pepe, Stephen Obaro, Bill G. Kapogiannis, James Bethel, and Katherine Luzuriaga

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Virologic and immunologic outcomes in HIV-infected Cambodian children after 18 months of highly active antiretroviral therapy (HAART), Sam Sophan, Chhour Y. meng, Polidy Pean, Joseph Harwell, Elizabeth Hutton, Sonia Trzmielina, Mohan Somasundaran, Katherine Luzuriaga, and David Pugatch

Publications from 2009

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Early initiation of lopinavir/ritonavir in infants less than 6 weeks of age: pharmacokinetics and 24-week safety and efficacy, Ellen Gould Chadwick, Jorge Pinto, Ram Yogev, Carmelita G. Alvero, Michael D. Hughes, Paul Palumbo, Brian Robbins, Rohan Hazra, Leslie Serchuck, Barbara E. Heckman, Lynette Purdue, Renee Browning, Katherine Luzuriaga, John Rodman, and Edmund V. Capparelli

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Identification of ongoing human immunodeficiency virus type 1 (HIV-1) replication in residual viremia during recombinant HIV-1 poxvirus immunizations in patients with clinically undetectable viral loads on durable suppressive highly active antiretroviral therapy, Carlum Shiu, Coleen K. Cunningham, Thomas C. Greenough, Petronella Muresan, Victor Sanchez-Merino, Vincent J. Carey, J. Brooks Jackson, Carrie Ziemniak, Lawrence Fox, Marvin Belzer, Stuart C. Ray, Katherine Luzuriaga, and Deborah Persaud

Publications from 2008

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Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy, Thomas C. Greenough, Coleen K. Cunningham, Petronella Muresan, Margaret M. McManus, Deborah Persaud, Terry Fenton, Piers Barker, Aditya Gaur, Dennis Panicali, John L. Sullivan, and Katherine Luzuriaga

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On the dynamics of acute EBV infection and the pathogenesis of infectious mononucleosis, Vey Hadinoto, Michael Shapiro, Thomas C. Greenough, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson

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Diminished human immunodeficiency virus type 1 DNA yield from dried blood spots after storage in a humid incubator at 37 degrees C compared to -20 degrees C, Caroline Mitchell, Cheryl Jennings, Donald Brambilla, Grace Aldrovandi, Angela Martin Amedee, Ingrid Beck, James W. Bremer, Robert Coombs, Don Decker, Susan A. Fiscus, Joseph Fitzgibbon, Katherine Luzuriaga, John Moye, Paul Palumbo, Patricia Reichelderfer, Mohan Somasundaran, Wendy Stevens, and Lisa Frenkel

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Lack of alternative coreceptor use by pediatric HIV-1 R5 isolates for infection of primary cord or adult peripheral blood mononuclear cells, W. Matthew Sullivan, P. Dorr, M. Perros, Richard W. Hudson Jr., Jean H. Leif, Katherine Luzuriaga, and Paul R. Clapham

Publications from 2007

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A virtual look at Epstein-Barr virus infection: biological interpretations, Karen A. Duca, Michael Shapiro, Edgar Delgado-Eckert, Vey hadinoto, Abdul S. Jarrah, Reinhard Laubenbacher, Kichol Lee, Katherine Luzuriaga, Nicholas F. Polys, and David A. Thorley-Lawson

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Cytomegalovirus (CMV) IE1- and pp65-specific CD8+ T cell responses broaden over time after primary CMV infection in infants, Laura L. Gibson, Sheryl Dooley, Sonia Trzmielina, Mohan Somasundaran, Donna Fisher, Maria Grazia Revello, and Katherine Luzuriaga

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Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA, Marie-Louise Newell, Sharon Huang, Simona Fiore, Claire Thorne, Laurent Mandelbrot, John L. Sullivan, Robert Maupin, Isaac Delke, D. Heather Watts, Richard D. Gelber, and Coleen K. Cunningham

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Virologic response to potent antiretroviral therapy and modeling of HIV dynamics in early pediatric infection, Paul Palumbo, Hulin Wu, Ellen Gould Chadwick, Ping Ruan, Katherine Luzuriaga, John Rodman, and Ram Yogev

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Influence of EBV on the peripheral blood memory B cell compartment, Tatyana A. Souza, B. David Stollar, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson

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Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants, Adriana H. Tremoulet, Edmund V. Capparelli, Parul Patel, Edward P. Acosta, Katherine Luzuriaga, Yvonne J. Bryson, Diane W. Wara, Carmen Zorrilla, Dianne Holland, and Mark Mirochnick

Publications from 2006

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Gender differences in lymphocyte populations, plasma HIV RNA levels, and disease progression in a cohort of children born to women infected with HIV, Marc Foca, Jack Moye, Clara Chu, Yvonne Matthews, Ken Rich, Edward Handelsman, Katherine Luzuriaga, Mary E. Paul, and Clemente Diaz

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Vaccines to prevent transmission of HIV-1 via breastmilk: scientific and logistical priorities, Katherine Luzuriaga, Marie-Louise Newell, Francios Dabis, Jean-Louis Excler, and John L. Sullivan

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Therapy with a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody reduces disease severity and viral burden in golden Syrian hamsters, Anjeanette Roberts, William D. Thomas, Jeannette Guarner, Elaine W. Lamirande, Gregory J. Babcock, Thomas C. Greenough, Leatrice Vogel, Norman Hayes, John L. Sullivan, Sherif Zaki, Kanta Subbarao, and Donna M. Ambrosino

Publications from 2005

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Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age, Ellen Gould Chadwick, John H. Rodman, Paula Britto, Christine Powell, Paul Palumbo, Katherine Luzuriaga, Michael Hughes, Elaine J. Abrams, Patricia M. Flynn, William Borkowsky, and Ram Yogev

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Nuclear localization of HIV type 1 Vif isolated from a long-term asymptomatic individual and potential role in virus attenuation, Melissa Ann Farrow, Mohan Somasundaran, Chengsheng Zhang, Dana Gabuzda, John L. Sullivan, and Thomas C. Greenough

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Development and characterization of a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody that provides effective immunoprophylaxis in mice, Thomas C. Greenough, Gregory J. Babcock, Anjeanette Roberts, Hector J. Hernandez, William D. Thomas, Jennifer A. Coccia, Robert F. Graziano, Mohan Srinivasan, Israel Lowy, Robert W. Finberg, Kanta Subbarao, Leatrice Vogel, Mohan Somasundaran, Katherine Luzuriaga, John L. Sullivan, and Donna M. Ambrosino

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Peripheral B cells latently infected with Epstein-Barr virus display molecular hallmarks of classical antigen-selected memory B cells, Tatyana A. Souza, B. David Stollar, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson

Publications from 2004

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The impact of race/ethnicity on mother-to-child HIV transmission in the United States in Pediatric AIDS Clinical Trials Group Protocol 316, Coleen K. Cunningham, Rajalakshmmi Balasubramanian, Isaac Delke, Robert Maupin, Lynne M. Mofenson, Alejandro Dorenbaum, John L. Sullivan, Adolfo Gonzalez-Garcia, Edwin Thorpe, Mobeen H. Rathore, and Richard D. Gelber

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Pneumococcal infections, William J. Durbin Jr.

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Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo, Donna Hochberg, Jaap M. Middeldorp, Michelle D. Catalina, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson

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Acute infection with Epstein-Barr virus targets and overwhelms the peripheral memory B-cell compartment with resting, latently infected cells, Donna Hochberg, Tatyana Souza, Michelle D. Catalina, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson

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Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2, Wenhui Li, Thomas C. Greenough, Michael J. Moore, Natalya Vasilieva, Mohan Somasundaran, John L. Sullivan, Michael Farzan, and Hyeryun Choe

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Immunogenicity and efficacy of childhood vaccines in HIV-1-infected children, S. K. Obaro, D. Pugatch, and Katherine Luzuriaga

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In utero HIV infection in pregnancies complicated by tuberculosis in Durban, South Africa, T. Pillay, M. Adhikari, Hoosen M. Coovadia, Jagidesa Moodley, M. Khan, and John L. Sullivan

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Vertical transmission of Mycobacterium tuberculosis in KwaZulu Natal: impact of HIV-1 co-infection, T. Pillay, A. W. Sturm, M. Khan, M. Adhikari, Jagidesa Moodley, Caitlin M. Connolly, Dhayendre Moodley, N. Padayatchi, A. Ramjee, Hoosen M. Coovadia, and John L. Sullivan

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Immunoprophylaxis to prevent mother-to-child transmission of HIV-1, Jeffrey T. Safrit, Ruth Ruprecht, Flavia Ferrantelli, Weidong Xu, Moiz Kitabwalla, Koen Van Rompay, Marta Marthas, Nancy Haigwood, John R. Mascola, Katherine Luzuriaga, Samuel Adeniyi Jones, Bonnie J. Mathieson, and Marie-Louise Newell

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Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms, Robert Winchester, Jane Pitt, Manhattan Charurat, Laurence S. Magder, Harald H. H. Goring, Alan Landay, Jennifer S. Read, William T. Shearer, Edward Handelsman, Katherine Luzuriaga, George V. Hillyer, and William A. Blattner

Publications from 2003

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Accuracy of the TRUGENE HIV-1 genotyping kit, Robert M. Grant, Daniel R. Kuritzkes, Victoria A. Johnson, John W. Mellors, John L. Sullivan, Ronald I. Swanstrom, Richard T. D'Aquila, Mark Van Gorder, Mark Holodniy, Robert M. Lloyd Jr., Caroline Reid, Gillian F. Morgan, and Dean L. Winslow

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Alterations in HIV-1 LTR promoter activity during AIDS progression, Kirsten Hiebenthal-Millow, Thomas C. Greenough, Doreen B. Bretttler, Michael Schindler, Steffen Wildum, John L. Sullivan, and Frank Kirchhoff

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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus, Wenhui Li, Michael J. Moore, Natalya Vasilieva, Jianhua Sui, Swee Kee Wong, Michael A. Berne, Mohan Somasundaran, John L. Sullivan, Katherine Luzuriaga, Thomas C. Greenough, Hyeryun Choe, and Michael Farzan

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Predose infant nevirapine concentration with the two-dose intrapartum neonatal nevirapine regimen: association with timing of maternal intrapartum nevirapine dose, Mark Mirochnick, Alejandro Dorenbaum, Suzette Blanchard, Coleen K. Cunningham, Richard D. Gelber, Lynne M. Mofenson, Mary Culnane, and John L. Sullivan

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A multicenter randomized controlled trial of nevirapine versus a combination of zidovudine and lamivudine to reduce intrapartum and early postpartum mother-to-child transmission of human immunodeficiency virus type 1, Dhayendre Moodley, Jagidesa Moodley, Hoosen Coovadia, Glenda Gray, James McIntyre, Justus Hofmyer, Cheryl Nikodem, David Hall, Maria Gigliotti, Patrick Robinson, Lynette Boshoff, and John L. Sullivan

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Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study, William T. Shearer, Howard M. Rosenblatt, Rebecca S. Gelman, Rebecca Oyomopito, Susan Plaeger, E. Richard Stiehm, Diane W. Wara, Steven D. Douglas, Katherine Luzuriaga, Elizabeth J. McFarland, Ram Yogev, Mobeen H. Rathore, Wende Levy, Bobbie L. Graham, and Stephen A. Spector

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Prevention of mother-to-child transmission of HIV--what next, John L. Sullivan

Publications from 2002

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Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human immunodeficiency virus type 1 transmission: a substudy of pediatric AIDS clinical trials group protocol 316, Coleen K. Cunningham, Marie-Laure Chaix, Claire Rekacewicz, Paula Britto, Christine Rouzioux, Richard D. Gelber, Alejandro Dorenbaum, Jean Francois Delfraissy, Brigitte Bazin, Lynne M. Mofenson, and John L. Sullivan

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Two-dose intrapartum/newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission: a randomized trial, Alejandro Dorenbaum, Coleen K. Cunningham, Richard D. Gelber, Mary Culnane, Lynne M. Mofenson, Paula Britto, Claire Rekacewicz, Marie-Louise Newell, Jean Francois Delfraissy, Bethann Cunningham-Scharder, Mark Mirochnick, and John L. Sullivan

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Enhanced culture method for detection of replication-competent virus in peripheral blood mononuclear cells of HIV type 1-infected individuals, John P. Haran, Thomas C. Greenough, Katherine Luzuriaga, John L. Sullivan, Timothy Flanigan, and Mohan Somasundaran

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Pediatric HIV-1 infection: advances and remaining challenges, Katherine Luzuriaga and John L. Sullivan

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Concentrations of protease inhibitors in cord blood after in utero exposure, Mark Mirochnick, Alejandro Dorenbaum, Dianne Holland, Bethann Cunningham-Scharder, Colleen K. Cunningham, Richard D. Gelber, Lynne M. Mofenson, Mary Culnane, James D. Connor, and John L. Sullivan

Publications from 2001

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Pharmacokinetics of nelfinavir in human immunodeficiency virus-infected infants, Edmund V. Capparelli, John L. Sullivan, Lynne M. Mofenson, Elizabeth Smith, Bobbie Graham, Paula Britto, Mark I. Becker, Dianne Holland, James D. Connor, and Katherine Luzuriaga

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Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS, Silke Carl, Thomas C. Greenough, Mandy Krumbiegel, Michael Greenberg, Jack Skowronski, John L. Sullivan, and Frank Kirchhoff

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Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 18-2001. A 19-month-old boy with fever and soft-tissue masses, William J. Durbin Jr. and Eugene J. Mark

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CD4 down-modulation by human immunodeficiency virus type 1 Nef correlates with the efficiency of viral replication and with CD4(+) T-cell depletion in human lymphoid tissue ex vivo, Svetlana Glushakova, Jan Munch, Silke Carl, Thomas C. Greenough, John L. Sullivan, Leonid Margolis, and Frank Kirchhoff

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Human immunodeficiency virus type 1 (HIV-1) gp120-specific antibodies in neonates receiving an HIV-1 recombinant gp120 vaccine, Elizabeth J. McFarland, William Borkowsky, Terry Fenton, Diane Wara, James McNamara, Pearl Samson, Minhee Kang, Lynne M. Mofenson, Coleen Cunningham, Ann-Marie Duliege, Faruk Sinangil, Stephen A. Spector, Eleanor Jimenez, Yvonne J. Bryson, Sandra K. Burchett, Lisa M. Frenkel, Ram Yogev, Francis Gigliotti, Katherine Luzuriaga, and Robert A. Livingston

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Population pharmacokinetics of dapsone in children with human immunodeficiency virus infection, Mark Mirochnick, Ellen Rae Cooper, Edmund V. Capparelli, Kenneth McIntosh, Jane Lindsey, Jing Xu, David Jacobus, Lynne M. Mofenson, Vincent R. Bonagura, Sharon Nachman, Ram Yogev, John L. Sullivan, and Stephen A. Spector

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Nevirapine pharmacokinetics in pregnant women and in their infants after in utero exposure, Mark Mirochnick, Sue Siminski, Terry Fenton, Miladi Lugo, and John L. Sullivan

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Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome, Hiroyuki Nakamura, Jodi Zarycki, John L. Sullivan, and Jae U. Jung

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The changing face of pediatric HIV-1 infection, John L. Sullivan and Katherine Luzuriaga

Publications from 2000

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Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection, Louis Alexander, Emma Weiskopf, Thomas C. Greenough, Nathan C. Gaddis, Marcy R. Auerbach, Malcolm H. Malim, Stephen J. O'Brien, Bruce D. Walker, John L. Sullivan, and Ronald C. Desrosiers

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Effect of HIV on thymic function before and after antiretroviral therapy in children, Daniel C. Douek, Richard A. Koup, Richard D. McFarland, John L. Sullivan, and Katherine Luzuriaga

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Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence, Ulrich Mahlknecht, Cheng Deng, Michael C. Lu, Thomas C. Greenough, John L. Sullivan, William A. O'Brien, and Georges Herbein

Publications from 1999

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Persistent HIV-1-specific CTL clonal expansion despite high viral burden post in utero HIV-1 infection, Christian Brander, Philip J. Goulder, Katherine Luzuriaga, Otto O. Yang, Kelly E. Hartman, Nathan G. Jones, Bruce D. Walker, and Spyros S. Kalams

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Long-term nonprogressive infection with human immunodeficiency virus type 1 in a hemophilia cohort, Thomas C. Greenough, Doreen B. Brettler, Frank Kirchhoff, Louis Alexander, Ronald C. Desrosiers, Stephen J. O'Brien, Mohan Somasundaran, Katherine Luzuriaga, and John L. Sullivan

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A polymorphism in the regulatory region of the CC-chemokine receptor 5 gene influences perinatal transmission of human immunodeficiency virus type 1 to African-American infants, Leondios G. Kostrikis, Avidan U. Neumann, Bruce Thomson, Bette T. Korber, Paul McHardy, Rose Karanicolas, Lisa Deutsch, Yaoxing Huang, Judy F. Lew, Kenneth McIntosh, Henry Pollack, William Borkowsky, Hans M. Speigel, Paul Palumbo, James Oleske, Arlene Bardeguez, Katherine Luzuriaga, John L. Sullivan, Steven M. Wolinsky, Richard A. Koup, David D. Ho, and John P. Moore

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Treatment of human immunodeficiency virus 1-infected infants and children with the protease inhibitor nelfinavir mesylate, Paul A. Krogstad, Andrew Wiznia, Katherine Luzuriaga, Wayne Danker, Karin Nielsen, Merril J. Gersten, Brad Kerr, Amy Hendricks, Barbara Boczany, Martin Rosenberg, Denna Jung, Stephen A. Spector, and Yvonne J. Bryson

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The abnormal gene in X-linked lymphoproliferative syndrome, John L. Sullivan

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The Ariel Project: A prospective cohort study of maternal-child transmission of human immunodeficiency virus type 1 in the era of maternal antiretroviral therapy, Russell B. Van Dyke, Bette T. Korber, Edwina Popek, Catherine Macken, Susan M. Widmayer, Arlene Bardeguez, I. Celine Hanson, Andrew Wiznia, Katherine Luzuriaga, Richard R. Viscarello, and Steven M. Wolinsky

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Frequent detection of escape from cytotoxic T-lymphocyte recognition in perinatal human immunodeficiency virus (HIV) type 1 transmission: the ariel project for the prevention of transmission of HIV from mother to infant, Cara C. Wilson, R. Clark Brown, Bette T. Korber, Barbara M. Wilkes, Debbie J. Ruhl, Doreen Sakamoto, Kevin Kuntsman, Katherine Luzuriaga, I. Celine Hanson, Susan M. Widmayer, Andrew Wiznia, Sheila Clapp, Arthur J. Ammann, Richard A. Koup, Steven M. Wolinsky, and Bruce D. Walker

Publications from 1998

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Changes in thymic function with age and during the treatment of HIV infection, Daniel C. Douek, Richard D. McFarland, Phillip H. Keiser, Earl A. Gage, Janice M. Massey, Barton F. Haynes, Michael A. Polis, Ashley T. Haase, Mark B. Feinberg, John L. Sullivan, Beth D. Jamieson, Jerome A. Zack, Louis J. Picker, and Richard A. Koup

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Prevention and treatment of pediatric HIV infection, Katherine Luzuriaga and John L. Sullivan

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Pharmacokinetics of nevirapine in human immunodeficiency virus type 1-infected pregnant women and their neonates. Pediatric AIDS Clinical Trials Group Protocol 250 Team, Mark Mirochnick, Terry Fenton, Paul Gagnier, Joseph W. Pav, Meg Gwynne, Sue Siminski, Rhoda S. Sperling, Karen Beckerman, Eleanor Jimenez, Ram Yogev, Stephen A. Spector, and John L. Sullivan