This collection showcases the journal articles and other publications authored by faculty and researchers in the Division of Hematology/Oncology in the Department of Pediatrics at the University of Massachusetts Medical School.

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Publications from 2013

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Weight Status of Children With Sickle Cell Disease, Anjulika Chawla, Philippa G. Sprinz, Jennifer Welch, Matthew Heeney, G. Naheed Usmani, Farzana Pashankar, and Patricia Kavanagh

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Improving Cultural Approaches to Pediatric Palliative Care in Central Massachusetts, Nancy E. Harger, RN, MS LIS; Usmani Naheed, MD; Jennifer Costa, PNP; and Estela McDonough

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Advances in understanding the pathogenesis of HLH, G. Naheed Usmani, Bruce A. Woda, and Peter E. Newburger

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HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells, Hang Zhao, Xueqing Zhang, Josias Brito Frazao, Antonio Condino-Neto, and Peter E. Newburger

Publications from 2012

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Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia, Hanna T. Gazda, Milena Preti, Mee Rie Sheen, Marie-Francoise O'Donohue, Adrianna Vlachos, Stella M. Davies, Antonis Kattamis, Leana Doherty, Michael Landowski, Christopher Buros, Roxanne Ghazvinian, Colin A. Sieff, Peter E. Newburger, Edyta Niewiadomska, Michal Matysiak, Bertil Glader, Eva Atsidaftos, Jeffrrey M. Lipton, Pierre-Emmanuel Gleizes, and Alan H. Beggs

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CTC1 Mutations in a patient with dyskeratosis congenita, Rachel B. Keller, Katelyn E. Gagne, G. Naheed Usmani, George K. Asdourian, David A. Williams, Inga Hofmann, and Suneet Agarwal

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Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways, Miroslav Koulnis, Ermelinda Porpiglia, P. Alberto Porpiglia, Ying Liu, Kelly N. Hallstrom, Daniel Hidalgo, and Merav Socolovsky

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Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes, Steven E. Lipshultz, Tracie L. Miller, Stuart R. Lipsitz, Donna S. Neuberg, Suzanne E. Dahlberg, Steven D. Colan, Lewis B. Silverman, Jacqueline M. Henkel, Vivian L. Franco, Laura L. Cushman, Barbara L. Asselin, Luis A. Clavell, Uma Athale, Bruno Michon, Caroline Laverdiere, Marshall A. Schorin, Eric Larsen, G. Naheed Usmani, and Stephen E. Sallan

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Stat5 Signaling Specifies Basal versus Stress Erythropoietic Responses through Distinct Binary and Graded Dynamic Modalities, Ermelinda Porpiglia, Daniel Hidalgo, Miroslav Koulnis, Abraham R. Tzafriri, and Merav Socolovsky

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Medication Errors in the Home: A Multisite Study of Children with Cancer, Kathleen E. Walsh, Douglas W. Roblin, Saul N. Weingart, Kathleen E. Houlahan, Barbara Degar, Amy Billett, Christopher P. Keuker, Colleen Biggins, Justin Li, Karen Wasilewski, and Kathleen M. Mazor

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The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells, Haojian Zhang, Cong Peng, Yiguo Hu, Huawei Li, Zhi Sheng, Yaoyu Chen, Con Sullivan, Jan Cerny, Lloyd Hutchinson, Anne Higgins, Patricia M. Miron, Xueqing Zhang, Michael A. Brehm, Dongguang Li, Michael R. Green, and Shaoguang Li

Publications from 2011

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Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease, Jacinta Bustamante, Andres A. Arias, Guillaume Vogt, Capucine Picard, Lizbeth Blancas Galicia, Carolina Prando, Audrey V. Grant, Christophe C. Marchal, Marjorie Hubeau, Ariane Chapgier, Ludovic de Beaucoudrey, Anne Puel, Jacqueline Feinberg, Ethan Valinetz, Lucile Janniere, Celine Besse, Anne Boland, Jean-Marie Brisseau, Stephane Blanche, Olivier Lortholary, Claire Fieschi, Jean-Francois Emile, Stephanie Boisson-Dupuis, Saleh Al-Muhsen, Bruce A. Woda, Peter E. Newburger, Antonio Condino-Neto, Mary C. Dinauer, Laurent Abel, and Jean-Laurent Casanova

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Global DNA demethylation during mouse erythropoiesis in vivo, Jeffrey R. Shearstone, Ramona Pop, Christoph Bock, Patrick Boyle, Alexander Meissner, and Merav Socolovsky

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Medication errors in the homes of children with chronic conditions, Kathleen E. Walsh, Kathleen M. Mazor, Christopher J. Stille, Irma Torres, Joann L. Wagner, Juliet Moretti, Kevin Chysna, Christy D. Stine, G. Naheed Usmani, and Jerry H. Gurwitz

Publications from 2010

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Hemophagocytic lymphohistiocytosis with MUNC13-4 gene mutation or reduced natural killer cell function prior to onset of childhood leukemia, Tamara Y. Chang, Julie Jaffray, Bruce A. Woda, Peter E. Newburger, and G. Naheed Usmani

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Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia, Leana Doherty, Mee Rie Sheen, Adrianna Vlachos, Valerie Choesmel, Marie-Francoise O'Donohue, Catherine Clinton, Hal E. Schneider, Colin A. Sieff, Peter E. Newburger, Sarah E. Ball, Edyta Niewiadomska, Michal Matysiak, Bertil Glader, Robert J. Arceci, Jason E. Farrar, Eva Atsidaftos, Jeffrrey M. Lipton, Pierre-Emmanuel Gleizes, and Hanna T. Gazda

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Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model, Jian-ming Li, Peter E. Newburger, Matthew J. Gounis, Phong Dargon, Xueqing Zhang, and Louis M. Messina

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Cyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes, Peter E. Newburger, Talia N. Pindyck, Zhiqing Zhu, Audrey Anna Bolyard, Andrew A.G. Aprikyan, David C. Dale, Gary D. Smith, and Laurence A. Boxer

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Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis, Karin Przyklenk, Andrew L. Frelinger III, Matthew Dean Linden, Peter Whittaker, YouFu Li, Marc R. Barnard, J. Adams, M. Morgan, H. Al-Shamma, and Alan D. Michelson

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Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy, Philip S. Rosenberg, Cornelia Zeidler, Audrey Anna Bolyard, Blanche P. Alter, Mary A. Bonilla, Laurence A. Boxer, Yigal Dror, Sally Kinsey, Daniel C. Link, Peter E. Newburger, Akiko Shimamura, Karl Welte, and David C. Dale

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X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils, Yukio Yasukochi, Osamu Maruyama, Milind C. Mahajan, Carolyn Padden, Ghia M. Euskirchen, Vincent Schulz, Hideki Hirakawa, Satoru Kuhara, Xing-Hua Pan, Peter E. Newburger, Michael Snyder, and Sherman M. Weissman

Publications from 2009

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Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH, M. Cattaneo, C. P. M. Hayward, K. A. Moffat, M. T. Pugliano, Y. Liu, and Alan D. Michelson

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Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors, Hung Chang, Ivan B. Yanachkov, Alan D. Michelson, YouFu Li, Marc R. Barnard, George E. Wright, and Andrew L. Frelinger III

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Platelet reactivity and the identification of acute coronary syndromes in the emergency department, Chad E. Darling, Alan D. Michelson, Gregory A. Volturo, and Karin Przyklenk

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Comment on "Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency", Paolo Ruggero Errante, Carolina Prando, Jacinta Bustamante, Walmir Cutrim Aragao-Filho, Paulo Vitor Soeiro Pereira, Jussara Rehder, Jean-Laurent Casanova, Peter E. Newburger, and Antonio Condino-Neto

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Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization, Andrew L. Frelinger III, YouFu Li, Matthew Dean Linden, Marc R. Barnard, Marsha L. Fox, Douglas J. Christie, Mark I. Furman, and Alan D. Michelson

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Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture, Milind C. Mahajan, Subhradip Karmakar, Peter E. Newburger, Diane S. Krause, and Sherman M. Weissman

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Methods for the measurement of platelet function, Alan D. Michelson

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Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial, Alan D. Michelson, Andrew L. Frelinger III, Eugene Braunwald, William E. Downey, Dominick J. Angiolillo, Nicholas P. Xenopoulos, Joseph A. Jakubowski, YouFu Li, Sabina A. Murphy, Jie Qin, Carolyn H. McCabe, Elliott M. Antman, and Stephen D. Wiviott

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Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials, Michelle L. O'Donoghue, Eugene Braunwald, Elliott M. Antman, Sabina A. Murphy, Eric R. Bates, Yoseph Rozenman, Alan D. Michelson, Raymond W. Hautvast, Peter N. Ver Lee, Sandra L. Close, Lei Shen, Jessica L. Mega, Marc S. Sabatine, and Stephen D. Wiviott

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Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS), V. Koneti Rao, Susan Price, Katie Perkins, Patricia Aldridge, Jean Tretler, Joie Davis, Janet K. Dale, Fred Gill, Kip R. Hartman, Linda C. Stork, David J. Gnarra, Lakshmanan Krishnamurti, Peter E. Newburger, Jennifer M. Puck, and Thomas Fleisher

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Nephropathy in type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity, Inge Tarnow, Alan D. Michelson, Marc R. Barnard, Andrew L. Frelinger III, Bent Aasted, Berit R. Jensen, Hans-Henrik Parving, Peter Rossing, and Lise Tarnow

Publications from 2008

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Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes, Eugene Braunwald, Dominick J. Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, Paul A. Gurbel, Alan D. Michelson, Eric D. Peterson, and Stephen D. Wiviott

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Antiplatelet therapy and platelet function testing, Eugene Braunwald, Dominick J. Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, Paul A. Gurbel, Alan D. Michelson, Eric D. Peterson, and Stephen D. Wiviott

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Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention, Eugene Braunwald, Dominick J. Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, Paul A. Gurbel, Alan D. Michelson, Eric D. Peterson, and Stephen D. Wiviott

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Investigating the mechanisms of hyporesponse to antiplatelet approaches, Eugene Braunwald, Dominick J. Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, Paul A. Gurbel, Alan D. Michelson, Eric D. Peterson, and Stephen D. Wiviott

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The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention, Eugene Braunwald, Dominick J. Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, Paul A. Gurbel, Alan D. Michelson, Eric D. Peterson, and Stephen D. Wiviott

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The active metabolite of prasugrel inhibits adenosine diphosphate- and collagen-stimulated platelet procoagulant activities, Andrew L. Frelinger III, Joseph A. Jakubowski, YouFu Li, Marc R. Barnard, Matthew Dean Linden, Inge Tarnow, Marsha L. Fox, Atsuhiro Sugidachi, Kenneth J. Winters, Mark I. Furman, and Alan D. Michelson

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Aspirin 'resistance': role of pre-existent platelet reactivity and correlation between tests, Andrew L. Frelinger III, YouFu Li, Matthew Dean Linden, Inge Tarnow, Marc R. Barnard, Marsha L. Fox, and Alan D. Michelson

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Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients, Hanna T. Gazda, Mee Rie Sheen, Adrianna Vlachos, Valerie Choesmel, Marie-Francoise O'Donohue, Hal Schneider, Natasha Darras, Catherine Hasman, Colin A. Sieff, Peter E. Newburger, Sarah E. Ball, Edyta Niewiadomska, Michal Matysiak, Jan M. Zaucha, Bertil Glader, Charlotte Niemeyer, Joerg J. Meerpohl, Eva Atsidaftos, Jeffrrey M. Lipton, Pierre-Emmanuel Gleizes, and Alan H. Beggs

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Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the Platelet Inhibition in Children On cLOpidogrel (PICOLO) trial, Jennifer S. Li, Eric Yow, Katherine Y. Berezny, Paula M. Bokesch, Matsato Talajasjo, Thomas P. Graham Jr., Stephen P. Sanders, Daniel Sidi, Damien Bonnet, Peter Ewert, Lisa K. Jennings, and Alan D. Michelson

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Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes, Marcos Luengo-Blanco, Carolina Prando, Jacinta Bustamante, Walmir Cutrim Aragao-Filho, Paulo Vitor Soeiro pereira, Jussara Rehder, Carolyn Padden, Jean-Laurent Casanova, Peter E. Newburger, and Antonio Condino-Neto

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Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients, Livia E. Marcal, Pericles M. Dias-da-Motta, Jussara Rehder, Ronei L. Mamoni, Maria Heloisa S. L. Blotta, Constance B. Whitney, Peter E. Newburger, Fernando F. Costa, Sara T. O. Saad, and Antonio Condino-Neto

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Antithrombotic therapy in neonates and children: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition), Paul Monagle, Elizabeth Chalmers, Anthony Chan, Gabrielle DeVeber, Fenella Kirkham, Patricia Massicotte, and Alan D. Michelson

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The American Society of Pediatric Hematology/Oncology distinguished career award goes to Laurence A. Boxer, MD, Peter E. Newburger and Valerie P. Castle

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Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia, Philip S. Rosenberg, Blanche P. Alter, Daniel C. Link, Steven Stein, Elin Rodger, Audrey Anna Bolyard, Andrew A.G. Aprikyan, Mary A. Bonilla, Yigal Dror, George Kanourakis, Peter E. Newburger, Laurence A. Boxer, and David C. Dale

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Effects of physiologic agonists on canine whole blood flow cytometry assays of leukocyte-platelet aggregation and platelet activation, Inge Tarnow, Annemarie T. Kristensen, Anne K.R. Krogh, Andrew L. Frelinger III, Marc R. Barnard, and Alan D. Michelson

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Platelet antistaphylococcal responses occur through P2X1 and P2Y12 receptor-induced activation and kinocidin release, Darin A. Trier, Kimberly D. Gank, Deborah Kupferwasser, Nannette Y. Young, William J. French, Alan D. Michelson, Leon I. Kupferwasser, Yan Q. Xiong, Arnold S. Bayer, and Michael R. Yeaman

Publications from 2007

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A molecular classification of congenital neutropenia syndromes, Laurence A. Boxer and Peter E. Newburger

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project, ENCODE Project Consortium, Job Dekker, Peter E. Newburger, and Xueqing Zhang

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The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin, Andrew L. Frelinger III, Joseph A. Jakubowski, YouFu Li, Marc R. Barnard, Marsha L. Fox, Matthew Dean Linden, Atsuhiro Sugidachi, Kenneth J. Winters, Mark I. Furman, and Alan D. Michelson

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Platelet function monitoring in patients with coronary artery disease, Paul A. Gurbel, Richard C. Becker, Kenneth G. Mann, Steven R. Steinhubl, and Alan D. Michelson

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Measuring antiplatelet drug effects in the laboratory, Paul Harrison, Andrew L. Frelinger III, Mark I. Furman, and Alan D. Michelson

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RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells, Hidenori Hattori, Xueqing Zhang, Yonghui Jia, Kulandayan K. Subramanian, Hakryul Jo, Fabien Loison, Peter E. Newburger, and Hongbo R. Luo

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Indices of platelet activation and the stability of coronary artery disease, Matthew Dean Linden, Mark I. Furman, Andrew L. Frelinger III, Marsha L. Fox, Marc R. Barnard, YouFu Li, Karin Przyklenk, and Alan D. Michelson

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Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance', Alan D. Michelson, Matthew Dean Linden, Mark I. Furman, YouFu Li, Marc R. Barnard, Marsha L. Fox, W. C. Lau, Thomas J. McLaughlin, and Andrew L. Frelinger III

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Cystic fibrosis heterozygotes do not have increased platelet activation, Inge Tarnow, Alan D. Michelson, Andrew L. Frelinger III, Matthew Dean Linden, YouFu Li, Marsha L. Fox, Marc R. Barnard, and Brian P. O'Sullivan

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Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial, Stephen D. Wiviott, Dietmar Trenk, Andrew L. Frelinger III, Michelle O'Donoghue, Franz-Josef Neumann, Alan D. Michelson, Dominick J. Angiolillo, Hanoch Hod, Gilles Montalescot, Debra L. Miller, Joseph A. Jakubowski, Richard Cairns, Sabina A. Murphy, Carolyn H. McCabe, Elliott M. Antman, and Eugene Braunwald

Publications from 2006

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Antiplatelet therapy in children, Sara J. Israels and Alan D. Michelson

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Preconditioning ischemia attenuates molecular indices of platelet activation-aggregation, Matthew Dean Linden, Peter Whittaker, Andrew L. Frelinger III, Marc R. Barnard, Alan D. Michelson, and Karin Przyklenk

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Arterial ischemic stroke in children: baby steps, Alan D. Michelson

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Aspirin resistance, Alan D. Michelson

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Evaluation of platelet function by flow cytometry, Alan D. Michelson

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Current options in platelet function testing, Alan D. Michelson, Andrew L. Frelinger III, and Mark I. Furman

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Frequency of aspirin resistance in a community hospital, Ahmadshah Mirkhel, Eliot Peyster, James Sundeen, Linda Greene, Alan D. Michelson, Ahmed Hasan, and Michael Domanski

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A limited number of genes are involved in the differentiation of germinal center B cells, Yasuhiro Nakayama, Paul Stabach, Stephen E. Maher, Milind C. Mahajan, Peter Masiar, Cheng Liao, Xueqing Zhang, Zhi-jia Ye, David Tuck, Alfred L.M. Bothwell, Peter E. Newburger, and Sherman M. Weissman

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Acute lymphocytic leukemia with eosinophilia and unusual karyotype, S. Rezk, L. Wheelock, J. A. Fletcher, A. M. Oliveira, Christopher P. Keuker, Peter E. Newburger, Bo Xu, Bruce A. Woda, and Patricia M. Miron

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Novel transcribed regions in the human genome, Joel Rozowsky, J. Wu, Zheng Lian, U. Nagalakshmi, J. O. Korbel, Philipp Kapranov, D. Zheng, S. Dyke, Peter E. Newburger, P. Miller, Thomas R. Gingeras, Sherman M. Weissman, Mark B. Gerstein, and Michael Snyder

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Nuclease sensitive element binding protein 1 associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation, Qichang Shen, Lin Fan, and Peter E. Newburger

Publications from 2005

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Chronic granulomatous disease in Latin American patients: clinical spectrum and molecular genetics, Piedad Agudelo-Florez, Carolina Cardoso prando-Andrade, Juan Alvaro Lopez, Beatriz Tavares Costa-Carvalho, Arnoldo Quezada, Francisco Jose Espinosa, Maria Aparecida de Souza Paiva, Persio Roxo Jr., Anete Grumach, Cristina Abe Jacob, Magda Maria Salles Carneiro-Sampaio, Peter E. Newburger, and Antonio Condino-Neto

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The effect of IFN-gamma and TNF-alpha on the NADPH oxidase system of human colostrum macrophages, blood monocytes, and THP-1 cells, Ana Carolina Almeida, Jussara Rehder, Silvana Dalge Severino, Jose Martins-Filho, Peter E. Newburger, and Antonio Condino-Neto

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Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity, Marc R. Barnard, Matthew Dean Linden, Andrew L. Frelinger III, YouFu Li, Marsha L. Fox, Mark I. Furman, and Alan D. Michelson

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Clopidogrel linking evaluation of platelet response variability to mechanism of action, Andrew L. Frelinger III and Alan D. Michelson

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GPIIb-IIIa antagonists reduce thromboinflammatory processes in patients with acute coronary syndromes undergoing percutaneous coronary intervention, Mark I. Furman, Lori A. Krueger, Matthew Dean Linden, Marsha L. Fox, Steven P. Ball, Marc R. Barnard, Andrew L. Frelinger III, and Alan D. Michelson

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The role of toll-like receptors in herpes simplex infection in neonates, Evelyn A. Kurt-Jones, John Belko, Catherine Yu, Peter E. Newburger, Jennifer P. Wang, Melvin Chan, David M. Knipe, and Robert W. Finberg

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Aspirin resistance: position paper of the Working Group on Aspirin Resistance, Alan D. Michelson, M. Cattaneo, J. W. Eikelboom, P. Gurbel, K. Kottke-Marchant, T. J. Kunicki, F. M. Pulcinelli, C. Cerletti, and A. K. Rao

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Noncompliance in cardiovascular clinical trials, Victor L. Serebruany, Benjamin R. Oshrine, Alex I. Malinin, Dan Atar, Alan D. Michelson, and James J. Ferguson III

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Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets, C. Robert Valeri, Hollace Macgregor, Marc R. Barnard, L. Summaria, Alan D. Michelson, and G. Ragno

Publications from 2004

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Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections, Piedad Agudelo-Florez, Beatriz T. Costa-Carvalho, Juan Alvaro Lopez, Jussara redher, Peter E. Newburger, Sara Teresinha Olalla-Saad, and Antonio Condino-Neto

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GPIIb/IIIa inhibitor-induced dethrombosis, Mark I. Furman, Andrew L. Frelinger III, and Alan D. Michelson

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A panorama of lineage-specific transcription in hematopoiesis, Yuval Kluger, Zheng Lian, Xueqing Zhang, Peter E. Newburger, and Sherman M. Weissman

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Lineage specificity of gene expression patterns, Yuval Kluger, David P. Tuck, Joseph T. Chang, Yasuhiro Nakayama, Ranjana Poddar, Nachiko Kohya, Zheng Lian, Abdelhakim Ben Nasr, H. Ruth Halaban, Diane S. Krause, Xueqing Zhang, Peter E. Newburger, and Sherman M. Weissman

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Application of flow cytometry to platelet disorders, Matthew Dean Linden, Andrew L. Frelinger III, Marc R. Barnard, Karin Przyklenk, Mark I. Furman, and Alan D. Michelson

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Superoxide release and cellular gluthatione peroxidase activity in leukocytes from children with persistent asthma, L. E. Marcal, J. Rehder, Peter E. Newburger, and Antonio Condino-Neto

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Role of iodine-131 MIBG scanning in the management of paediatric patients with neuroblastoma, G. M. Shah Syed, H. Naseer, G. Naheed Usmani, and M. A. Cheema

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Pretherapy Gallium-67 scanning in paediatric patients with Hodgkin's disease, G. M. Shah Syed, M. N. Younis, G. Naheed Usmani, and N. Zafar

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In vitro testing of fresh and lyophilized reconstituted human and baboon platelets, C. Robert Valeri, Hollace Macgregor, Marc R. Barnard, L. Summaria, Alan D. Michelson, and G. Ragno

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Gene expression in mature neutrophils: early responses to inflammatory stimuli, Xueqing Zhang, Yuval Kluger, Yasuhiro Nakayama, Ranjana Poddar, Constance Whitney, Adam DeTora, Sherman M. Weissman, and Peter E. Newburger

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p47(phox) PX domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton, Yong Zhan, Dandan He, Peter E. Newburger, and G. Wayne Zhou

Publications from 2003

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Platelet FcgammaRIIA His131Arg polymorphism and platelet function: antibodies to platelet-bound fibrinogen induce platelet activation, J. Chen, J-F. Dong, C. Sun, A. Bergeron, L. McBride, M. Pillai, Marc R. Barnard, J. Salmon, Alan D. Michelson, and Paul F. Bray

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The cleaved peptide of PAR1 is a more potent stimulant of platelet-endothelial cell adhesion than is thrombin, R. Brannon Claytor, Alan D. Michelson, Jian-Ming Li, Andrew L. Frelinger III, Michael J. Rohrer, Charles S. C. Garnette, Marc R. Barnard, Lori A. Krueger, and Mark I. Furman

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Quantification of abciximab-induced platelet inhibition is assay dependent: a comparative study in patients undergoing percutaneous coronary intervention, Mark I. Furman, Dean J. Kereiakes, Lori A. Krueger, Michele N. Mueller, Thomas M. Broderick, John F. Schneider, Wendy L. Howard, Marsha L. Fox, Marc R. Barnard, Andrew L. Frelinger III, and Alan D. Michelson

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Neonatal platelet function, Sara J. Israels, Margaret L. Rand, and Alan D. Michelson

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The hemostatic defect of cardiopulmonary bypass, Matthew Dean Linden

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The effect of IFN-gamma and TNF-alpha on the eosinophilic differentiation and NADPH oxidase activation of human HL-60 clone 15 cells, Juan A. Lopez, Peter E. Newburger, and Antonio Condino-Neto

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How platelets work: platelet function and dysfunction, Alan D. Michelson

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Platelet inhibitor therapy: mechanisms of action and clinical use, Alan D. Michelson

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Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis, W. Beau Mitchell, Ji Hong Li, Fiza Singh, Alan D. Michelson, James Bussel, Barry S. Coller, and Deborah L. French

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Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide, Yasuhiro Tsukahara, Zheng Lian, Xueqing Zhang, Constance Whitney, Yuval Kluger, David Tuck, Shigeru Yamaga, Yasuhiro Nakayama, Sherman M. Weissman, and Peter E. Newburger

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Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 13-2003. A 14-month-old boy with hepatomegaly, perianal lesions, and a bony lump on the forehead, G. Naheed Usmani, Sjirk J. Westra, and Souhad Younes