Cellulose as a matrix for nucleic acid purification

UMMS Affiliation

Department of Pediatrics; New England Newborn Screening Program



Document Type


Medical Subject Headings

Cellulose; DNA


Genetics and Genomics | Medical Genetics | Pediatrics


Nucleic acid purification is an essential but tedious step in molecular biology studies, which has been made easier since the introduction of solid binding matrix. However, the application of each type of available matrix is often limited to a specific group of nucleic acids. We have discovered a matrix, secondary fibril-associated cellulose (designated as SFcellulose), that can be used as a general-purpose matrix to isolate a wide range of nucleic acids with high yield and quality.

Rights and Permissions

Citation: Anal Biochem. 1999 Feb 15;267(2):415-8. Link to article on publisher's site

Related Resources

Link to Article in PubMed