Department of Pediatrics
Medical Subject Headings
Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Obesity; Adolescent; Child
Endocrine System Diseases | Endocrinology, Diabetes, and Metabolism | Pediatrics
The global pandemic of obesity in children and adolescents has resulted in a new expression of diabetes mellitus designated as double diabetes. The entity encompasses the autoimmune load of Type 1 Diabetes and the metabolic load of Type 2 Diabetes. There is no consensus on the best therapeutic modality for this new expression of diabetes mellitus. Optimal therapeutic options must address the coexistence of both metabolic and autoimmune components of diabetes mellitus in the patient. There have also been calls to revise the current classification of diabetes mellitus to take into account the surging prevalence of double diabetes in children and adolescents.
Nwosu, Benjamin U., "Double Diabetes: The Evolving Treatment Paradigm in Children and Adolescents" (2013). Endocrinology/Diabetes. 39.