Department of Pediatrics, Division of Endocrinology
Medical Subject Headings
Pseudohypoparathyroidism; Fibrous Dysplasia, Polyostotic; Child; Adolescent
Endocrinology, Diabetes, and Metabolism | Pediatrics
Summary: Albright hereditary osteodystrophy (AHO) is a genetic syndrome characterized by a distinctive set of developmental and skeletal defects that may easily be misdiagnosed as exogenous obesity in children. There are very few publications detailing the comprehensive management of children and adolescents with this disorder. This chapter provides a comprehensive discussion of the various aspects of this disorder. At the end, the reader should be able to: (1) List the clinical features of Albright hereditary osteodystrophy, (2) Identify the genetic and molecular abnormalities of AHO, (3) List the clinical features of pseudohypoparathyroidism type 1a (PHP 1a), (4) Describe the management of children and adolescents with PHP 1a.
Citation: Benjamin U. Nwosu (2011). Pseudohypoparathyroidism in Children, Contemporary Aspects of Endocrinology, Evanthia Diamanti-Kandarakis (Ed.), ISBN: 978-953-307-357-6, InTech, Available from: http://www.intechopen.com/articles/show/title/pseudohypoparathyroidism-in-children