The Department of Orthopedics and Physical Rehabilitation, along with the Division of Rheumatology, form the renowned UMMS/UMMHC Musculoskeletal Center of Excellence. The Center focuses on clinical care and research for the prevention, diagnosis, treatment and rehabilitation of musculoskeletal disorders. Patients have access to preventive, diagnostic, treatment and rehabilitation services for musculoskeletal injuries and disorders. This includes a direct link to the advanced, highly specialized services located on the three UMMS/UMMHC campuses.

This collection showcases the journal articles and other publications and presentations written by faculty and researchers of the Department of Orthopedics and Physical Rehabilitation.

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Publications from 2009

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Anatomical reconstruction for chronic lateral ankle instability in the high-demand athlete: functional outcomes after the modified Brostrom repair using suture anchors, Xinning Li, Heather Killie, Patrick Guerrero, and Brian D. Busconi

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Does incorrect level needle localization during anterior cervical discectomy and fusion lead to accelerated disc degeneration, Ahmad Nassr, Joon Y. Lee, Rubin S. Bashir, Jeffrey A. Rihn, Jason C. Eck, James D. Kang, and Moe R. Lim

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Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications, Jie Song, Jianwen Xu, Tera M. Filion, Eduardo Saiz, Antoni P. Tomsia, Jane B. Lian, Gary S. Stein, David C. Ayers, and Carolyn R. Bertozzi

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Effects of poly(2-hydroxyethyl methacrylate) and poly(vinyl-pyrrolidone) hydrogel implants on myopic and normal chick sclera, James Su, Elena Iomdina, Elena Tarutta, Brian Ward, Jie Song, and Christine F. Wildsoet

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Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor, John J. Wixted, Paul J. Fanning, Tripti Gaur, Shannon L. O'Connell, Jason Silva, April Mason-Savas, David C. Ayers, Gary S. Stein, and Jane B. Lian

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Sustained and localized in vitro release of BMP-2/7, RANKL, and tetracycline from FlexBone, an elastomeric osteoconductive bone substitute, Jianwen Xu, Xinning Li, Jane B. Lian, David C. Ayers, and Jie Song

Publications from 2008

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Ankle fractures in the elderly: initial and long-term outcomes, Sarah A. Anderson, Xinning Li, Patricia D. Franklin, and John J. Wixted

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The risk of reintubation following anterior cervical spine surgery, Dahari Brooks, Mark S. Eskander, Jonathan Eskander, Patricia D. Franklin, Patrick J. Connolly, Henry Claude Sagi, and K. Daniel Riew

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The proximal biceps tendon: tricks and pearls, Brian D. Busconi, Nicola Deangelis, and Patrick Guerrero

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Relationship of the internal carotid artery to the anterior aspect of the C1 vertebra: implications for C1-C2 transarticular and C1 lateral mass fixation, Bradford L. Currier, Tim P. Maus, Jason C. Eck, Dirk R. Larson, and Michael J. Yaszemski

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Fixation strength of unicortical versus bicortical C1-C2 transarticular screws, Steven J. Cyr, Bradford L. Currier, Jason C. Eck, Andrew Foy, Qingshan Chen, Dirk R. Larson, Michael J. Yaszemski, and Kai-Nan An

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Use of the trauma pelvic orthotic device (T-POD) for provisional stabilisation of anterior-posterior compression type pelvic fractures: a cadaveric study, Nicola Deangelis, John J. Wixted, Jacob M. Drew, Mark S. Eskander, Jonathan P. Eskander, and Bruce G. French

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Comparison of vertebroplasty and balloon kyphoplasty for treatment of vertebral compression fractures: a meta-analysis of the literature, Jason C. Eck, Dean Nachtigall, S. Craig Humphreys, and Scott D. Hodges

Delayed presentation of metastatic melanoma of the cervical spine, Jason C. Eck, Marc A. Tressler, and Steven J. Triantafyllou

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A left knee wound complication by non-Hodgkins lymphoma in bilateral total knee arthroplasties, Mark S. Eskander, Erika McPhee, Jonathan P. Eskander, Robert Nascimento, Jeremy J. McCormick, Suyang Hao, David Shepro, and Kirk Johnson

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Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants, Jonathan B. Fitzgerald, Moonsoo Jin, Diana H. Chai, Patrick Siparsky, Paul J. Fanning, and Alan J. Grodzinsky

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The Chitranjan Ranawat Award: functional outcome after total knee replacement varies with patient attributes, Patricia D. Franklin, Wenjun Li, and David C. Ayers

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Hyperthermia associated osteonecrosis in young patients with pelvic malignancies, Marcus Jager, Stefan Balzer, Rudiger Wessalowski, J. Schaper, Ulrich Gobel, Xinning Li, and Rudiger Krauspe

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Dexamethasone modulates BMP-2 effects on mesenchymal stem cells in vitro, Marcus Jager, Johannes Fischer, Wiebke Dohrn, Xinning Li, David C. Ayers, Akos Czibere, Wolf Christian Prall, Sabine Lensing-Hohn, and Rudiger Krauspe

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Osteoblast differentiation onto different biometals with an endoprosthetic surface topography in vitro, Marcus Jager, F. Urselmann, F. Witte, K. Zanger, Xinning Li, David C. Ayers, and Rudiger Krauspe

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Intravascular uptake during fluoroscopically guided cervical interlaminar steroid injection at C6-7: a case report, Mark S. Kaplan, Joseph Cunniff, John Cooke, and Jeremy Giere Collins

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Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc(R)) treatment: A case series and review of the literature, Xinning Li, Agam Shah, Patricia D. Franklin, Renee J. Merolli, Jill Bradley, and Brian D. Busconi

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An improved murine femur fracture device for bone healing studies, Joseph E. Marturano, Benjamin C. Cleveland, Melissa A. Bryne, Shannon L. O'Connell, John J. Wixted, and Kristen L. Billiar

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Imaging in pelvic osteomyelitis: support for early magnetic resonance imaging, Erika McPhee, Jonathan P. Eskander, Mark S. Eskander, Susan T. Mahan, and Errol Mortimer

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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells, Jitesh Pratap, John J. Wixted, Tripti Gaur, Sayyed K. Zaidi, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian

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Urgent surgical decompression compared to methylprednisolone for the treatment of acute spinal cord injury: a randomized prospective study in beagle dogs, Richard S. Rabinowitz, Jason C. Eck, C. Michel Harper Jr., Dirk R. Larson, Miguel A. Jimenez, Joseph E. Parisi, Jonathan A. Friedman, Michael J. Yaszemski, and Bradford L. Currier

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Reuse of external fixation components: a randomized trial, Jinsil K. Sung, Rafael Levin, Jodi Siegel, Thomas A. Einhorn, William R. Creevy, and Paul Tournetta III

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Computer-aided surgery: assessing the accuracy of a navigation system, Douglas R. Weiss, John J. Wixted, and Richard C. Anderson

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Paecilomyces lilacinus olecranon bursitis in an immunocompromised host: case report and review, Mireya Wessolossky, John P. Haran, and Kaushik Bagchi

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Neuromuscular complications of nutritional deficiencies, Faren H. Williams

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The effect of an orthopedic trauma room on after-hours surgery at a level one trauma center, John J. Wixted, Mark A. Reed, Mark S. Eskander, Bryce Millar, Richard C. Anderson, Kaushik Bagchi, Shubjeet Kaur, Patricia D. Franklin, and Walter J. Leclair

Publications from 2007

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Imaging assessment of lumbar pedicle screw placement: sensitivity and specificity of plain radiographs and computer axial tomography, Dahari Brooks, Mark S. Eskander, Steve Balsis, Nat Ordway, and Patrick J. Connolly

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Understanding the superior clear space in the adult ankle, Joseph P. Deangelis, Richard C. Anderson, and Nicola Deangelis

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Does medial tenderness predict deep deltoid ligament incompetence in supination-external rotation type ankle fractures, Nicola Deangelis, Mark S. Eskander, and Bruce G. French

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Analysis of pedicle and translaminar facet fixation in a multisegment interbody fusion model, Mark S. Eskander, Dahari Brooks, Nat Ordway, Elizabeth Dale, and Patrick J. Connolly

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Worksite e-mail health promotion trial: Early lessons, Patricia D. Franklin, Robert Ploutz-Snyder, Paula F. Rosenbaum, Michael P. Carey, Nancy Smith, and Michael F. Roizen

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Primary repair of knee dislocations: results in 25 patients (28 knees) at a mean follow-up of four years, Brett D. Owens, Mark Neault, Emily Benson, and Brian D. Busconi

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A chemical and engineering approach towards "smart" synthetic bone grafts, Jie Song

Publications from 2006

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Pilot study of methods to document quantity and variation of independent patient exercise and activity after total knee arthroplasty, Patricia D. Franklin, Joseph McLaughlin, Catherine B. Boisvert, Wenjun Li, and David C. Ayers

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Using sequential e-mail messages to promote health behaviors: evidence of feasibility and reach in a worksite sample, Patricia D. Franklin, Paula F. Rosenbaum, Michael P. Carey, and Michael F. Roizen

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Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation, Tripti Gaur, Lillian Rich, Christopher J. Lengner, Sadiq Hussain, Brune Trevant, David C. Ayers, Janet L. Stein, Peter V. N. Bodine, Barry S. Komm, Gary S. Stein, and Jane B. Lian

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Nanomechanical analysis of bone tissue engineering scaffolds, Jessica D. Kaufman, Jie Song, and Catherine M. Klapperich

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The floating shoulder, B. D. Owens and Thomas P. Goss

Arthroscopy for hip dislocation and fracture-dislocation, Brett D. Owens and Brian D. Busconi

Publications from 2005

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Total knee replacement outcome and coexisting physical and emotional illness, David C. Ayers, Patricia D. Franklin, Robert Ploutz-Snyder, and Catherine B. Boisvert

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The posterior shearing tibial plateau fracture: treatment and results via a posterior approach, Timothy Bhattacharyya, L. Pearce McCarty 3rd, Mitchell B. Harris, Suzanne M. Morrison, John J. Wixted, Mark S. Vrahas, and R. Malcolm Smith

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Neuromuscular rehabilitation and electrodiagnosis. 4. Pediatric issues, Chong-Tae Kim, Jeffrey A. Strommen, Jeffery S. Johns, Jay M. Weiss, Lyn D. Weiss, Faren H. Williams, and Ira G. Rashbaum

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Mineralization of synthetic polymer scaffolds: a bottom-up approach for the development of artificial bone, Jie Song, Viengkham Malathong, and Carolyn R. Bertozzi

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Neuromuscular rehabilitation and electrodiagnosis. 3. Diseases of muscles and neuromuscular junction, Jeffrey A. Strommen, Jeffery S. Johns, Chong-Tae Kim, Faren H. Williams, Lyn D. Weiss, Jay M. Weiss, and Ira G. Rashbaum

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Biomimetic Bonelike Composites and Novel Bioactive Glass Coatings, Antoni P. Tomsia, Eduardo Saiz, Jie Song, and Carolyn R. Bertozzi

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Neuromuscular rehabilitation and electrodiagnosis. 2. Peripheral neuropathy, Lyn D. Weiss, Jay M. Weiss, Jeffery S. Johns, Jeffrey A. Strommen, Chong-Tae Kim, Faren H. Williams, and Ira G. Rashbaum

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The effect of valgus/varus malalignment on load distribution in total knee replacements, Frederick W. Werner, David C. Ayers, Lorin P. Maletsky, and Paul J. Rullkoetter

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Neuromuscular rehabilitation and electrodiagnosis. 1. Mononeuropathy, Faren H. Williams, Jeffery S. Johns, Jay M. Weiss, Lyn D. Weiss, Chong-Tae Kim, Jeffrey A. Strommen, and Ira G. Rashbaum

Publications from 2004

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Psychological attributes of preoperative total joint replacement patients: implications for optimal physical outcome, David C. Ayers, Patricia D. Franklin, Paula M. Trief, Robert Ploutz-Snyder, and Deborah Freund

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Functional lipid microstructures immobilized on a gold electrode for voltammetric biosensing of cholera toxin, Quan Cheng, Shimin Zhu, Jie Song, and Na Zhang

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Anatomy of the superficial peroneal nerve in relation to fixation of tibia fractures with the less invasive stabilization system, Joseph P. Deangelis, Nicola Deangelis, and Richard C. Anderson

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Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and pathogenesis, with a report of an additional case in a child, Emily Ko, Errol Mortimer, and Armando E. Fraire

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Early cementing does not increase debond energy of grit blasted interfaces, Kenneth A. Mann, Leatha A. Damron, Amos Race, and David C. Ayers

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Cement microcracks in thin-mantle regions after in vitro fatigue loading, Kenneth A. Mann, Sameer Gupta, Amos Race, Mark A. Miller, Richard J. Cleary, and David C. Ayers

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Functional glass slides for in vitro evaluation of interactions between bone cells and mineral-binding surfaces, Jie Song, Julia Chen, Catherine M. Klapperich, Vincent Eng, and Carolyn R. Bertozzi

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Functional self-assembling bolaamphiphilic polydiacetylenes as colorimetric sensor scaffolds, Jie Song, Justin S. Cisar, and Carolyn R. Bertozzi

Publications from 2003

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The importance of proximal cement filling of the calcar region: a biomechanical justification, David C. Ayers and Kenneth A. Mann

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Assessment and differential diagnosis of the painful hip, Nicola Deangelis and Brian D. Busconi

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Hip arthroscopy in the pediatric population, Nicola Deangelis and Brian D. Busconi

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Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage, Paul J. Fanning, Gregory Emkey, Robert J. Smith, Alan J. Grodzinsky, Nora Szasz, and Stephen B. Trippel

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Polymorphisms and the pocketbook: the cost-effectiveness of cytochrome P450 2C19 genotyping in the eradication of Helicobacter pylori infection associated with duodenal ulcer, David F. Lehmann, Joseph J. Medicis, and Patricia D. Franklin

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Hip arthroscopy: surgical approach, positioning, and distraction, J. Bohannon Mason, Joseph C. McCarthy, John O'Donnell, Wael Barsoum, Michael B. Mayor, Brian D. Busconi, Viktor E. Krebs, and Brett D. Owens

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A new approach to mineralization of biocompatible hydrogel scaffolds: an efficient process toward 3-dimensional bonelike composites, Jie Song, Eduardo Saiz, and Carolyn R. Bertozzi

Publications from 2001

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Defining the relationship between obesity and total joint arthroplasty, Beverly Stickles, Leslie Phillips, Williams Timothy Brox, Brett D. Owens, and William L. Lanzer

Publications from 2000

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Using data to evaluate hospital inpatient mortality, Patricia D. Franklin and James P. Legault

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Using data to reduce hospital readmissions, Patricia D. Franklin, Cheryl M. Noetscher, Mark E. Murphy, and Ronald J. Lagoe

Publications from 1999

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The Local Perspective: Health Care Delivery in Syracuse, NY, Patricia D. Franklin

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Cost reduction and outcome improvement in the intensive care unit, William H. Marx, Nancy L. DeMaintenon, Katherine F. Mooney, Michael L. Mascia, Joseph Medicis, Patricia D. Franklin, Edward Sivak, and Leo Rotello

Publications from 1998

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Comparing the history-taking methods used during a preanesthesia visit: the HealthQuiz versus the written questionnaire, Richard A. Beers, Colleen E. O'Leary, and Patricia D. Franklin

Publications from 1991

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Quantifying bone loss from the proximal femur after total hip arthroplasty, C. Kearns McCarthy, Gerald G. Steinberg, M. Agren, Daniel Leahey, E. Wyman, and Daniel T. Baran

Publications from 1990

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Innovations in clinical practice through hospital-funded grants, Patricia D. Franklin, R. J. Panzer, L. P. Brideau, and P. F. Griner

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Preoperative localization of osteoid osteoma: a new technique that uses CT, Gerald G. Steinberg, James M. Coumas, and Thomas Breen

Publications from 1989

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Familial synovial chondromatosis: brief report, Gerald G. Steinberg, Sanjay S. Desai, Rajwant K. Malhotra, and Roger B. Hickler