Diagnosis and management of clostridium perfringens sepsis and uterine gas gangrene

UMMS Affiliation

Department of Obstetrics and Gynecology



Document Type


Medical Subject Headings

Adult; Bacteremia; *Clostridium perfringens; Diagnosis, Differential; Female; Gas Gangrene; Humans; Hysterectomy; Infant, Newborn; Male; Meconium Aspiration Syndrome; Penicillins; Pregnancy; Pregnancy Complications, Infectious; Uterine Diseases


Obstetrics and Gynecology


The progression of Clostridium perfringens endomyometritis to gas gangrene is a rare, but greatly feared complication in the obstetrical patient. While endometritis following cesarean delivery is a common complication, recognition of C. perfringens as the pathogen as well as its progression to gas formation in the myometrium is essential to the survival of the patient. We present a patient that we recently cared for, and review the bacteriology, clinical diagnosis, and management.

Rights and Permissions

Citation: Obstet Gynecol Surv. 2002 Jan;57(1):53-7.

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