Primary angiosarcoma of the ovary: a case report of Stage I disease

UMMS Affiliation

Department of Obstetrics and Gynecology



Document Type


Medical Subject Headings

Adult; Antineoplastic Combined Chemotherapy Protocols; dosage; Chemotherapy, Adjuvant; Dacarbazine; Doxorubicin; Female; Hemangiosarcoma; Humans; Ifosfamide; Mesna; Neoplasm Staging; Ovarian Neoplasms


Obstetrics and Gynecology


BACKGROUND: There are 20 documented cases of primary ovarian angiosarcoma. Most patients present with metastatic disease and respond poorly to chemotherapy. There is little information available to counsel early-staged patients on the need for or efficacy of adjuvant chemotherapy.

CASE: We present a case of Stage Ic primary ovarian angiosarcoma treated with 3 cycles of adjuvant MAID chemotherapy. The patient is without evidence of disease 10 months post-operatively.

CONCLUSION: A review of the literature indicates a potential role for MAID chemotherapy in the treatment of ovarian angiosarcomas. Detection of Stage I disease appears to confer a better prognosis regardless of the utilization of adjuvant chemotherapy.

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Citation: Gynecol Oncol. 2005 Oct;99(1):218-21. Link to article on publisher's site

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