Title

Primary angiosarcoma of the ovary: a case report of Stage I disease

UMMS Affiliation

Department of Obstetrics and Gynecology

Date

10-6-2005

Document Type

Article

Medical Subject Headings

Adult; Antineoplastic Combined Chemotherapy Protocols; dosage; Chemotherapy, Adjuvant; Dacarbazine; Doxorubicin; Female; Hemangiosarcoma; Humans; Ifosfamide; Mesna; Neoplasm Staging; Ovarian Neoplasms

Disciplines

Obstetrics and Gynecology

Abstract

BACKGROUND: There are 20 documented cases of primary ovarian angiosarcoma. Most patients present with metastatic disease and respond poorly to chemotherapy. There is little information available to counsel early-staged patients on the need for or efficacy of adjuvant chemotherapy.

CASE: We present a case of Stage Ic primary ovarian angiosarcoma treated with 3 cycles of adjuvant MAID chemotherapy. The patient is without evidence of disease 10 months post-operatively.

CONCLUSION: A review of the literature indicates a potential role for MAID chemotherapy in the treatment of ovarian angiosarcomas. Detection of Stage I disease appears to confer a better prognosis regardless of the utilization of adjuvant chemotherapy.

Rights and Permissions

Citation: Gynecol Oncol. 2005 Oct;99(1):218-21. Link to article on publisher's site

Related Resources

Link to Article in PubMed