Presumed and definite bacteremia in extremely low gestational age newborns
Authors
Patel, SonalDammann, Olaf
Martin, Camilia R.
Allred, Elizabeth N.
Leviton, Alan
Bednarek, Francis
Delpapa, Ellen
Xu, Bo
ELGAN Study Investigators
UMass Chan Affiliations
Department of Obstetrics and GynecologyDocument Type
Journal ArticlePublication Date
2011-01-18Keywords
BacteremiaFemale
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
Male
Risk
*Terminology as Topic
Time Factors
Obstetrics and Gynecology
Metadata
Show full item recordAbstract
AIM: To explore risk patterns for presumed and definite, early and late neonatal bacteremia. METHODS: We studied 1106 extremely low gestational age newborns who survived until postnatal day 28. We defined early definite bacteremia as a positive bacterial culture in the first week and definite late bacteremia as a positive bacterial culture in week 2, 3 or 4. Bacteremia was presumed if antibiotics were given for more than 72 h despite negative blood cultures. RESULTS: Risk patterns did not differ much for presumed and definite bacteremia in the first postnatal month. While maternal and pregnancy characteristics were associated with early bacteremia, neonatal comorbidities, especially NEC, were the main antecedents/correlates of late bacteremia. All four categories of bacteremia were associated with younger gestational age and lower birth weight. Infants with presumed and definite bacteremia had similar distributions of days of ventilation and oxygenation. CONCLUSION: Definite and presumed late bacteremias have rather similar risk patterns, while those of early and late bacteremia differ appreciably. Paediatrica.Source
Acta Paediatr. 2011 Jan;100(1):36-41. doi: 10.1111/j.1651-2227.2010.01963.x. Epub 2010 Aug 16. Link to article on publisher's siteDOI
10.1111/j.1651-2227.2010.01963.xPermanent Link to this Item
http://hdl.handle.net/20.500.14038/42802PubMed ID
20712830Notes
Francis Bednarek, Ellen Delpapa and Bo Xu participated in this study as ELGAN Study Investigators.
Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1111/j.1651-2227.2010.01963.x