Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2016

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A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis, Stephen M. Carpenter, Claudio Nunes-Alves, Matthew G. Booty, Sing Sing Way, and Samuel M. Behar

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Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs, Jenny Chen, Alexander A. Shishkin, Xiaopeng Zhu, Sabah Kadri, Itay Maza, Mitchell Guttman, Jacob H. Hanna, Aviv Regev, and Manuel Garber

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Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes, Henry Huang, Eric S. Veien, Hong Zhang, David C. Ayers, and Jie Song

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Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD), Takako I. Jones, Megan Parilla, and Peter L. Jones

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Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland, Guangyuan Li, Isaac N. Hayward, Brittany R. Jenkins, Heather M. Rothfuss, Coleman H. Young, Marja T. Nevalainen, Aaron Muth, Paul R. Thompson, Amy M. Navratil, and Brian D. Cherrington

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Clinical expression of facioscapulohumeral muscular dystrophy in carriers of 1-3 D4Z4 reduced alleles: experience of the FSHD Italian National Registry, Ana Nikolic and Rossella Tupler

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MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory, Alex Tek, Andrei A. Korostelev, and Samuel Coulbourn Flores

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Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress, Santiago Vernia, Caroline Morel, Joseph C. Madara, Julie Cavanagh-Kyros, Tamera Barrett, Kathryn O. Chase, Norman J. Kennedy, Dae Young Jung, Jason K. Kim, Neil Aronin, Richard A. Flavell, Bradford B. Lowell, and Roger J. Davis

Publications from 2015

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The p53R172H Mutant Does Not Enhance Hepatocellular Carcinoma Development and Progression, Leanne G. Ahronian, David R. Driscoll, David S. Klimstra, and Brian C. Lewis

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The PsychENCODE project, Schahram Akbarian, Zhiping Weng, Eugenio Mattei, Michael Purcaro, Junko Tsuji, Geetha Senthil, Thomas Lehner, Pamela Sklar, Nenad Sestan, and PsychENCODE Consortium

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OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease, Thomas E. Akie, Lijun Liu, Minwoo Nam, Shi Lei, and Marcus P. Cooper

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Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation, Heather E. Arsenault, Jagoree Roy, Claudine E. Mapa, Martha S. Cyert, and Jennifer A. Benanti

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alphabeta T cell receptors as predictors of health and disease, Meriem Attaf, Eric Huseby, and Andrew K. Sewell

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DRC3 connects the N-DRC to dynein g to regulate flagellar waveform, Junya Awata, Kangkang Song, Jianfeng Lin, Stephen M. King, Michael J. Sanderson, Daniela Nicastro, and George B. Witman

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Using joint registry data from FORCE-TJR to improve the accuracy of risk-adjustment prediction models for thirty-day readmission after total hip replacement and total knee replacement, David C. Ayers, Thomas K. Fehring, Susan M. Odum, and Patricia D. Franklin

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Evaluating implementation of methicillin-resistant Staphylococcus aureus (MRSA) prevention guidelines in spinal cord injury centers using the PARIHS framework: a mixed methods study, Salva N. Balbale, Jennifer N. Hill, Marylou Guihan, Timothy P. Hogan, Kenzie A. Cameron, Barry Goldstein, and Charlesnika T. Evans

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Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells, Ahmet Rasim Barutcu, Bryan R. Lajoie, Rachel Patton McCord, Coralee E. Tye, Deli Hong, Terri L. Messier, Gillian Browne, Andre J. van Wijnen, Jane B. Lian, Janet L. Stein, Job Dekker, Anthony N. Imbalzano, and Gary S. Stein

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Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans, Lea M. Beaulieu, Lauren Clancy, Kahraman Tanriverdi, Emelia J. Benjamin, Carolyn D. Kramer, Ellen O. Weinberg, Xianbao He, Samrawit Mekasha, Eric O. Mick, Robin R. Ingalls, Caroline A. Genco, and Jane E. Freedman

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A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B, Aniuska Becerra-Artiles, Omar Dominguez-Amorocho, Lawrence J. Stern, and J. Mauricio Calvo-Calle

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Cognitive testing for dementia is adversely affected by administration in a foreign location, Cynthia Bechtel, Ruth Remington, Bruce A. Barton, Constance Barysauskas, and Thomas B. Shea

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The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer, Jon-Matthew Belton, Bryan R. Lajoie, Sylvain Audibert, Sylvain Cantaloube, Imen Lassadi, Isabelle Goiffon, Davide Bau, Marc A. Marti-Renom, Kerstin Bystricky, and Job Dekker

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Sequential dengue virus infections detected in active and passive surveillance programs in Thailand, 1994-2010, Piraya Bhoomiboonchoo, Ananda Nisalak, Natkamol Chansatiporn, In-Kyu Yoon, Siripen Kalayanarooj, Mathuros Thipayamongkolgul, Timothy Endy, Alan L. Rothman, Sharone Green, Anon Srikiatkhachorn, Darunee Buddhari, Mammen P. Mammen, and Robert V. Gibbons

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Glypican Is a Modulator of Netrin-Mediated Axon Guidance, Cassandra Blanchette, Paola N. Perrat, Andrea Thackeray, and Claire Y. Benard

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Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism, Charles Blatti, Majid Kazemian, Scot A. Wolfe, Michael H. Brodsky, and Saurabh Sinha

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Health evaluation and referral assistant: a randomized controlled trial to improve smoking cessation among emergency department patients, Edwin D. Boudreaux, Beau Abar, Brianna Haskins, Brigitte Bauman, and Grant Grissom

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GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function, Alondra Schweizer Burguete, Sandra Almeida, Fen-Biao Gao, Robert Kalb, Michael R. Akins, and Nancy M. Bonini

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Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial, Gerd R. Burmester, William F. Rigby, Ronald F. van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ariella Kelman, Sophie Dimonaco, and Nina Mitchell

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Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo, Emerald Butko, Martin Distel, Claire Pouget, Bart Weijts, Isao Kobayashi, Kevin Ng, Christian Mosimann, Fabienne E. Poulain, Adam McPherson, Chih-Wen Ni, David L. Stachura, Natasha Del Cid, Raquel Espin-Palazon, Nathan D. Lawson, Richard Dorsky, Wilson K. Clements, and David Traver

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A Social-Ecological View of Barriers and Facilitators for HIV Treatment Adherence: Interviews with Puerto Rican HIV Patients, Eida M. Castro, Lydia E. Santiago, Julio C. Jimenez, Daira Davila-Vargas, and Milagros C. Rosal

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Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans, Can Cenik, Elif Sarinay Cenik, Gun W. Byeon, Fabian Grubert, Sophie I. Candille, Damek Spacek, Bilal Alsallakh, Hagen Tilgner, Carlos L. Araya, Hua Tang, Emiliano P. Ricci, and Michael P. Snyder

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Proyecto Mama: a lifestyle intervention in overweight and obese Hispanic women: a randomised controlled trial--study protocol, Lisa Chasan-Taber, Bess H. Marcus, Milagros C. Rosal, Katherine L. Tucker, Sheri J. Hartman, Penelope S. Pekow, Edward J. Stanek III, Barry Braun, Caren G. Solomon, JoAnne Manson, Sarah L. Goff, and Glenn Markenson

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Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation, Hui Cheng, Sha Hao, Yanfeng Liu, Yakun Pang, Shihui Ma, Fang Dong, Jing Xu, Guoguang Zheng, Shaoguang Li, Weiping Yuan, and Tao Cheng

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Decade-Long Trends in 30-Day Rehospitalization Rates After Acute Myocardial Infarction, Han-Yang Chen, Mayra Tisminetzky, Kate L. Lapane, Jorge L. Yarzebski, Sharina D. Person, Catarina I. Kiefe, Joel Gore, and Robert J. Goldberg

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Narratives to enhance smoking cessation interventions among African-American smokers, the ACCE project, Andrea Cherrington, Jessica H. Williams, Pamela Payne Foster, Heather L. Coley, Connie Kohler, Jeroan J. Allison, Catarina I. Kiefe, Julie E. Volkman, and Thomas K. Houston

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Hyperspectral Imaging as an Early Biomarker for Radiation Exposure and Microcirculatory Damage, Michael S. Chin, Brian B. Freniere, Luca Lancerotto, Jorge R. Lujan-Hernandez, Jonathan H. Saleeby, Yuan-Chyuan Lo, Dennis P. Orgill, Janice F. Lalikos, and Thomas J. Fitzgerald

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A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression, Hyoung-Soo Cho, HyunMu Shin, Helena Haberstock-Debic, Yan Xing, Timothy D. Owens, Jens Oliver. Funk, Ronald J. Hill, J. Michael Bradshaw, and Leslie J. Berg

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Inherited CHST11/MIR3922 deletion is associated with a novel recessive syndrome presenting with skeletal malformation and malignant lymphoproliferative disease, Sameer S. Chopra, Ignaty Leshchiner, Hatice Duzkale, Heather McLaughlin, Monica Giovanni, Chengsheng Zhang, Nathan Stitziel, Joyce D. Fingeroth, Robin M. Joyce, Matthew Lebo, Heidi Rehm, Dana Vuzman, Richard Maas, Shamil R. Sunyaev, Michael Murray, and Christopher A. Cassa

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Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs, Min-Te Chou, Bo W. Han, Chiung-Po Hsiao, Phillip D. Zamore, Zhiping Weng, and Jui-Hung Hung

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Impact on survival of the number of lymph nodes resected in patients with lymph node-negative gastric cancer, Xiaoyuan Chu and Zhongfa Yang

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Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics, Hannah Clapham, Derek A. Cummings, Ananda Nisalak, Siripen Kalayanarooj, Butsaya Thaisomboonsuk, Chonticha Klungthong, Stefan Fernandez, Anon Srikiatkhachorn, Louis R. Macareo, Justin Lessler, Julia Reiser, and In-Kyu Yoon

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Relationship among Glutamine, gamma-Aminobutyric Acid, and Social Cognition in Autism Spectrum Disorders, David E. Cochran, Elif M. Sikoglu, Steven M. Hodge, Richard A.E. Edden, Ann Foley, David N. Kennedy, Constance M. Moore, and Jean A. Frazier

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Improving patient notification of solid abdominal viscera incidental findings with a standardized protocol, Courtney E. Collins, Nicole Cherng, Theodore P. McDade, Babak Movahedi, Timothy A. Emhoff, Giles F. Whalen, Jennifer LaFemina, and Jon D. Dorfman

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Utilizing small nutrient compounds as enhancers of exercise-induced mitochondrial biogenesis, Daniel M. Craig, Stephen P. Ashcroft, Micah Y. Belew, Ben Stocks, Kevin Currell, Keith Baar, and Andrew Philp

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MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis, Timea Csak, Shashi Bala, Dora Lippai, Karen Kodys, Donna Catalano, Arvin Iracheta-Vellve, and Gyongyi Szabo

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Cotton rat immune responses to virus-like particles containing the pre-fusion form of respiratory syncytial virus fusion protein, Lori McGinnes Cullen, Jorge C. G. Blanco, and Trudy G. Morrison

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Characterization of functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in HIV-infected children and youth, Donna J. Curtis, Petronella Muresan, Sharon Nachman, Terence Fenton, Kelly M. Richardson, Teresa Dominguez, Patricia M. Flynn, Stephen A. Spector, Coleen K. Cunningham, Anthony Bloom, and Adriana Weinberg

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Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues, Laura V. Danai, Rachel J. Roth Flach, Joseph V Virbasius, Lorena Garcia Menendez, Dae Young Jung, Jong Hun Kim, Jason K. Kim, and Michael P. Czech

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TRANSIT - A Software Tool for Himar1 TnSeq Analysis, Michael A. DeJesus, Chaitra Ambadipudi, Richard E. Baker, Christopher M. Sassetti, and Thomas R. Ioerger

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The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease, Xianjun Dong, Junko Tsuji, Adam Labadorf, Panos Roussos, Jiang-Fan Chen, Richard H. Myers, Schahram Akbarian, and Zhiping Weng

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Quantitative Correlation of in Vivo Properties with in Vitro Assay Results: The in Vitro Binding of a Biotin-DNA Analogue Modifier with Streptavidin Predicts the in Vivo Avidin-Induced Clearability of the Analogue-Modified Antibody, Shuping Dou, John Virostko, Dale L. Greiner, Alvin C. Powers, and Guozheng Liu

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Detecting Heart Failure Decompensation by Measuring Transthoracic Bioimpedance in the Outpatient Setting: Rationale and Design of the SENTINEL-HF Study, Silviu Dovancescu, Jane S. Saczynski, Chad E. Darling, Jarno Riistema, Fatima Sert Kuniyoshi, Theo E. Meyer, Robert J. Goldberg, and David D. McManus

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Ultrasonography of adnexal causes of acute pelvic pain in pre-menopausal non-pregnant women, Carolyn S. Dupuis and Young H. Kim

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A Prospective Controlled Trial of an Electronic Hand Hygiene Reminder System, Richard T. Ellison III, Constance Barysauskas, Elke A. Rundensteiner, Di Wang, and Bruce A. Barton

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Connecting Circadian Genes to Neurodegenerative Pathways in Fruit Flies, Patrick Emery

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Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors, David Ermert, Jutamas Shaughnessy, Thorsten Joeris, Jakub Kaplan, Catherine J. Pang, Evelyn A. Kurt-Jones, Peter A. Rice, Sanjay Ram, and Anna M. Blom

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Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture, Marta Esteves da Silva, Max Adrian, Philipp Schatzle, Joanna Lipka, Takuya Watanabe, Sukhee Cho, Kensuke Futai, Corette J. Wierenga, Lukas C. Kapitein, and Casper C. Hoogenraad

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FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1), Sandra J. Feeney, Meagan J. McGrath, Absorn Sriratana, Stefan M. Gehrig, Gordon S. Lynch, Colleen E. D'Arcy, John T. Price, Catriona A. McLean, Rossella Ginevra Tupler, and Christina A. Mitchell

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The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse, Francesca Finetti, Laura Patrussi, Donatella Galgano, Chiara Cassioli, Giuseppe Perinetti, Gregory J. Pazour, and Cosima T. Baldari

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Family Outbreaks of Nontyphoidal Salmonellosis following a Meal of Guinea Pigs, John B. Fournier, Kimberly Knox, Maureen Harris, and Michael Newstein

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Epigenomics and the structure of the living genome, Nir Friedman and Oliver J. Rando

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Marginal structural models for the estimation of the risk of Diabetes Mellitus in the presence of elevated depressive symptoms and antidepressant medication use in the Women's Health Initiative observational and clinical trial cohorts, Christine Frisard, Xiangdong Gu, Brian Whitcomb, Yunsheng Ma, Penelope Pekow, Martha Zorn, Deidre M. Sepavich, and Raji Balasubramanian

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AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity, Sebastian P. Fuchs, Jose M. Martinez-Navio, Michael Piatak Jr., Jeffrey D. Lifson, Guangping Gao, and Ronald C. Desrosiers

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Acceleration of wound healing by alpha-gal nanoparticles interacting with the natural anti-Gal antibody, Uri Galili

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Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice, Michal Ganz, Terence N. Bukong, Timea Csak, Banishree Saha, Jin-Kyu Park, Aditya Ambade, Karen Kodys, and Gyongyi Szabo

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An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis, Neeta Garg and Thomas W. Smith

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A randomized controlled trial of smartphone-based mindfulness training for smoking cessation: a study protocol, Kathleen A. Garrison, Prasanta Pal, Rahil Rojiani, Jesse Dallery, Stephanie S. O'Malley, and Judson A. Brewer

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Predictors for long-term survival free from whole brain radiation therapy in patients treated with radiosurgery for limited brain metastases, Daniel Gorovets, Paul Rava, Daniel K. Ebner, David J. Tybor, Deus Cielo, Yakub Puthawala, Timothy J. Kinsella, Thomas A. DiPetrillo, David E. Wazer, and Jaroslaw T. Hepel

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Civilian deaths from weapons used in the Syrian conflict, Debarati Guha-Sapir, Jose M. Rodriguez-Llanes, Madelyn J. Hsiao-Rei Hicks, Anne-Francoise Donneau, Adam Coutts, Louis Lillywhite, and Fouad M. Fouad

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Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics, Sunita Gulati, Ian C. Schoenhofen, Dennis M. Whitfield, Andrew D. Cox, Jianjun Li, Frank St Michael, Evgeny V. Vinogradov, Jacek Stupak, Bo Zheng, Makoto Ohnishi, Magnus Unemo, Lisa A. Lewis, Rachel E. Taylor, Corinna S. Landig, Sandra Diaz, George W. Reed, Ajit Varki, Peter A. Rice, and Sanjay Ram

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Regulation of Nucleosome Architecture and Factor Binding Revealed by Nuclease Footprinting of the ESC Genome, Sarah J. Hainer and Thomas G. Fazzio

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Spatial re-organization of myogenic regulatory sequences temporally controls gene expression, Akihito Harada, Chandrashekara Mallappa, Seiji Okada, John T. Butler, Stephen P. Baker, Jeanne B. Lawrence, Yasuyuki Ohkawa, and Anthony N. Imbalzano

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Comparative effectiveness and safety of rituximab versus subsequent anti-tumor necrosis factor therapy in patients with rheumatoid arthritis with prior exposure to anti-tumor necrosis factor therapies in the United States Corrona registry, Leslie R. Harrold, George W. Reed, Robert P. Magner, Ashwini Shewade, Ani John, Jeffrey D. Greenberg, and Joel M. Kremer

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Effectiveness of Rituximab for the Treatment of Rheumatoid Arthritis in Patients with Prior Exposure to Anti-TNF: Results from the CORRONA Registry, Leslie R. Harrold, George W. Reed, Ashwini Shewade, Robert P. Magner, Katherine Saunders, Ani John, Joel M. Kremer, and Jeffrey D. Greenberg

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Feasibility of an Assessment Tool for Children's Competence to Consent to Predictive Genetic Testing: a Pilot Study, Irma M. Hein, Pieter W. Troost, Robert Lindeboom, Imke Christiaans, Thomas Grisso, Johannes B. van Goudoever, and Ramon J.L. Lindauer

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Near-infrared photoactivatable control of Ca signaling and optogenetic immunomodulation, Lian He, Yuanwei Zhang, Guolin Ma, Peng Tan, Zhan Jun Li, Shengbing Zhang, Xiang Wu, Ji Jing, Shaohai Fang, Lijuan Zhou, Youjun Wang, Yun Huang, Patrick Hogan, Gang Han, and Yubin Zhou

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Venous-derived angioblasts generate organ-specific vessels during embryonic development, Gideon Hen, Julian Nicenboim, Oded Mayseless, Lihee Asaf, Masahiro Shin, Giorgia Busolin, Roy Hofi, Gabriella Almog, Natascia Tiso, Nathan D. Lawson, and Karina Yaniv

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An optimized kit-free method for making strand-specific deep sequencing libraries from RNA fragments, Erin E. Heyer, Hakan Ozadam, Emiliano P. Ricci, Can Cenik, and Melissa J. Moore

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Facioscapulohumeral muscular dystrophy as a model for epigenetic regulation and disease, Charis L. Himeda, Takako I. Jones, and Peter L. Jones

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DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients, Isabella C. Hirako, Carolina Gallego-Marin, Marco A. Ataide Oswalso Cruz Founda, Warrison A. Andrade, Humberto Gravina, Bruno C. Rocha, Rosane B. de Oliveira, Dhelio B. Pereira, Joseph Vinetz, Betty Diamond, Sanjay Ram, Douglas T. Golenbock, and Ricardo T. Gazzinelli

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miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement, Andrew G. Hoss, Adam Labadorf, Jeanne C. Latourelle, Vinay K. Kartha, Tiffany C. Hadzi, James F. Gusella, Marcy E. MacDonald, Jiang-Fan Chen, Schahram Akbarian, Zhiping Weng, Jean Paul Vonsattel, and Richard H. Myers

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Evaluating the QUIT-PRIMO clinical practice ePortal to increase smoker engagement with online cessation interventions: a national hybrid type 2 implementation study, Thomas K. Houston, Rajani S. Sadasivam, Jeroan J. Allison, Arlene S. Ash, Midge N. Ray, Thomas M. English, Timothy P. Hogan, and Daniel E. Ford

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Impact of Thromboprophylaxis across the US Acute Care Setting, Wei Huang, Frederick A. Anderson Jr., Sophie K. Rushton-Smith, and Alexander T. Cohen

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Comparative Genomics Reveals Chd1 as a Determinant of Nucleosome Spacing in Vivo, Amanda Hughes and Oliver J. Rando

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Role of T cell-glial cell interactions in creating and amplifying central nervous system inflammation and multiple sclerosis disease symptoms, Eric Huseby, Daisuke Kamimura, Yasunobu Arima, Caitlin S. Parello, Katsuhiro Sasaki, and Masaaki Murakami

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Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6, Yu-Jie Hu, Houda Belaghzal, Wen-Yu Hsiao, Jun Qi, James E. Bradner, David A. Guertin, Said Sif, and Anthony N. Imbalzano

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Tachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in Drosophila, Seol Hee Im, Kendra Takle, Juyeon Jo, Daniel T. Babcock, Zhiguo Ma, Yang Xiang, and Michael J. Galko

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Neutrophil Responses to Sterile Implant Materials, Siddharth Jhunjhunwala, Stephanie Aresta-DaSilva, Katherine Tang, David Alvarez, Matthew J. Webber, Benjamin C. Tang, Danya M. Lavin, Omid Veiseh, Joshua C. Doloff, Suman Bose, Arturo Vegas, Minglin Ma, Gaurav Sahay, Alan Chiu, Andrew Bader, Erin Langan, Sean Siebert, Jie Li, Dale L. Greiner, Peter E. Newburger, Ulrich H. von Andrian, Robert Langer, and Daniel G. Anderson

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Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy, Takako I. Jones, Oliver D. King, Charis L. Himeda, Sachiko Homma, Jennifer C. J. Chen, Mary Lou. Beermann, Chi Yan, Charles P. Emerson Jr., Jeffrey B. Miller, Kathryn R. Wagner, and Peter L. Jones

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Feasibility, acceptability, and characteristics associated with adherence and completion of a culturally relevant internet-enhanced physical activity pilot intervention for overweight and obese young adult African American women enrolled in college, Rodney P. Joseph, Gareth R. Dutton, Andrea Cherrington, Kevin Fontaine, Monica Baskin, Krista Casazza, Danielle Lorch, Jeroan J. Allison, and Nefertiti H. Durant

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Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination, Tatenda Kadungure, Anna J. Ucher, Erin K. Linehan, Carol E. Schrader, and Janet Stavnezer

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Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3, Seokwon Kang, Teresa Fernandes-Alnemri, Corey Rogers, Lindsey Mayes, Ying Wang, Christopher P. Dillon, Linda Roback, William Kaiser, Andrew Oberst, Junji Sagara, Katherine A. Fitzgerald, Douglas R. Green, Jianke Zhang, Edward S. Mocarski, and Emad S. Alnemri

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Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo, Georg Karpel-Massler, Chang Shu, Lily Chau, Matei Banu, Marc-Eric Halatsch, Mike-Andrew Westhoff, Yulian P. Ramirez, Alonzo H. Ross, Jeffrey N. Bruce, Peter Canoll, and Markus D. Siegelin

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Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells, Lyne Khair, Richard E. Baker, Erin K. Linehan, Carol E. Schrader, and Janet Stavnezer

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Palliative care in gynecological cancer, Shelley M. Kibel and Joanna M. Cain

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Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria, Karen J. Kieser, Cara C. Boutte, Jemila C. Kester, Christina E. Baer, Amy K. Barczak, Xavier Meniche, Michael C. Chao, E Hesper Rego, Christopher M. Sassetti, Sarah M. Fortune, and Eric J. Rubin

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The Antioxidant Activity and Their Major Antioxidant Compounds from Acanthopanax senticosus and A. koreanum, Young-Hyun Kim, Myoung Lae Cho, Dan-Bi Kim, Gi-Hae Shin, Jin-Ha Lee, Jong Seok Lee, Sun-Ok Park, Sang-Jong Lee, Hyun Mu Shin, and Ok-Hwan Lee

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Evaluation of Cardiac Involvement in Children with Dengue by Serial Echocardiographic Studies, Tawatchai Kirawittaya, In-Kyu Yoon, Sineewanlaya Wichit, Sharone Green, Francis A. Ennis, Robert V. Gibbons, Stephen J. Thomas, Alan L. Rothman, Siripen Kalayanarooj, and Anon Srikiatkhachorn

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Parental smoke exposure and the development of nicotine craving in adolescent novice smokers: the roles of DRD2, DRD4, and OPRM1 genotypes, Marloes Kleinjan, Rutger C.M.E. Engels, and Joseph R. DiFranza

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The genetics of hepatitis C virus underlie its ability to escape humoral immunity, Jay K. Kolls and Gyongyi Szabo

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Serotonin Syndrome in the Setting of Lamotrigine, Aripiprazole, and Cocaine Use, Anupam Kotwal and Sarah L. Cutrona