Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2016

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A Modular Assembly Platform for Rapid Generation of DNA Constructs, Elliot Akama-Garren, Nik Joshi, Tuomas Tammela, Gregory P. Chang, Bethany L. Wagner, Da-Yae Lee, William M. Rideout Iii, Thales Papagiannakopoulos, Wen Xue, and Tyler Jacks

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Incidence of Dengue Virus Infection in Adults and Children in a Prospective Longitudinal Cohort in the Philippines, Maria Theresa Alera, Anon Srikiatkhachorn, John Mark Velasco, Ilya A. Tac-An, Catherine B. Lago, Hannah Clapham, Stefan Fernandez, Jens W. Levy, Butsaya Thaisomboonsuk, Chonticha Klungthong, Louis R. Macareo, Ananda Nisalak, Laura L. Hermann, Daisy Villa, and In-Kyu Yoon

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Culturally adaptive storytelling method to improve hypertension control in Vietnam - "We talk about our hypertension": study protocol for a feasibility cluster-randomized controlled trial, Jeroan J. Allison, Hoa L. Nguyen, Duc A. Ha, German A. Pihan, Ha N. Ly, Hanh T. Tran, Ngoc T. Phan, Nguyen C. Vu, Minjin Kim, and Robert J. Goldberg

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Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1alpha activation, Aditya Ambade, Abhishek Satishchandran, and Gyongyi Szabo

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Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates, Florie Borel, Gwladys Gernoux, Brynn Cardozo, Jake P. Metterville, Gabriela Toro Cabrera, Lina Song, Qin Su, Guang Ping Gao, Mai K. Elmallah, Robert H. Brown Jr., and Christian Mueller

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A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis, Stephen M. Carpenter, Claudio Nunes-Alves, Matthew G. Booty, Sing Sing Way, and Samuel M. Behar

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Drosophila Vision Depends on Carcinine Uptake by an Organic Cation Transporter, Ratna Chaturvedi, Zhuo Luan, Peiyi Guo, and Hong-Sheng Li

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Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans, Hilary K. Cheesman, Rhonda Feinbaum, Jose Thekkiniath, Robert H. Dowen, Annie L. Conery, and Read Pukkila-Worley

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Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs, Jenny Chen, Alexander A. Shishkin, Xiaopeng Zhu, Sabah Kadri, Itay Maza, Mitchell Guttman, Jacob H. Hanna, Aviv Regev, and Manuel Garber

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Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression, Beatriz Araujo Cortez, Paula Rezende-Teixeira, Sambra D. Redick, Stephen J. Doxsey, and Glaucia Maria Machado-Santelli

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Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3), Christopher J. Edwards, Francisco J. Blanco, Jeffrey Crowley, Charles Birbara, Janusz Jaworski, Jacob Aelion, Randall M. Stevens, Adele Vessey, Xiaojiang Zhan, and Paul Bird

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Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment, Eliver Eid Ghosn Bou, Jeffrey Waters, Megan Phillips, Ryo Yamamoto, Brian R. Long, Yang Yang, Rachel M. Gerstein, Cheryl A. Stoddart, Hiromitsu Nakauchi, and Leonore A. Herzenberg

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Diabetes Is Associated with Worse Clinical Presentation in Tuberculosis Patients from Brazil: A Retrospective Cohort Study, Leonardo Gil-Santana, Jilson L. Almeida-Junior, Carolina A.M. Oliveira, Lucas S. Hickson, Carla Daltro, Simone Castro, Hardy Kornfeld, Eduardo M. Netto, and Bruno B. Andrade

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Genomic insights into the Ixodes scapularis tick vector of Lyme disease, Monika Gulia-Nuss,; Daniel R. Caffrey; Neal S. Silverman; Adam R. Wespiser; and Catherine A. Hill

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Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes, Henry Huang, Eric S. Veien, Hong Zhang, David C. Ayers, and Jie Song

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Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD), Takako I. Jones, Megan Parilla, and Peter L. Jones

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Results of a Culturally Adapted Internet-Enhanced Physical Activity Pilot Intervention for Overweight and Obese Young Adult African American Women, Rodney P. Joseph, Dori Pekmezi, Gareth R. Dutton, Andrea Cherrington, Young-Il Kim, Jeroan J. Allison, and Nefertiti H. Durant

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Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012, Nomana M. Khan, Emily S. Jentes, Clive Brown, Pauline Han, Sowmya R. Rao, Phyllis Kozarsky, Stefan H.F. Hagmann, Regina C. LaRocque, Edward T. Ryan, and Global TravEpiNet Consortium (GTEN)

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Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin, Tomohiro Kubo, Jason Brown, Karl D. Bellve, Branch Craige, Julie M. Craft, Kevin E. Fogarty, Karl-Ferdinand Lechtreck, and George B. Witman

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Palliative cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion: current clinical practice or misnomer, Laura A. Lambert and Ariana Harris

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Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase, Scott E. LeBlanc, Qiong Wu, Pallavi Lamba, Said Sif, and Anthony N. Imbalzano

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Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study, Jane J. Lee, Alison Pedley, Udo Hoffmann, Joseph Massaro, John F. Keaney Jr., Ramachandran S. Vasan, and Caroline S. Fox

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Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland, Guangyuan Li, Isaac N. Hayward, Brittany R. Jenkins, Heather M. Rothfuss, Coleman H. Young, Marja T. Nevalainen, Aaron Muth, Paul R. Thompson, Amy M. Navratil, and Brian D. Cherrington

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Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress, Chen Lin, Xinyuan Zhao, Desen Sun, Lingda Zhang, Wenpan Fang, Tingjia Zhu, Qiang Wang, Botao Liu, Saisai Wei, Guangdi Chen, Zhengping Xu, and Xiangwei Gao

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DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia, You Li, Hisato Yagi, Gregory M. Hendricks, Gregory J. Pazour, and Cecilia W. Lo

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The Causes of HIV-Associated Cardiomyopathy: A Tale of Two Worlds, Rebecca H. Lumsden and Gerald S. Bloomfield

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Safety of anticoagulation with uninterrupted warfarin vs. interrupted dabigatran in patients requiring an implantable cardiac device, Shivanshu Madan, Purushothaman Muthusamy, Katie L. Mowers, Darryl A. Elmouchi, Bohuslav Finta, Andre J. Gauri, Alan K. Woelfel, Timothy D. Fritz, Alan T. Davis, and Nagib T. Chalfoun

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Genomic Access to Monarch Migration Using TALEN and CRISPR/Cas9-Mediated Targeted Mutagenesis, Matthew J. Markert, Ying Zhang, Metewo Selase Enuameh, Steven M. Reppert, Scot A. Wolfe, and Christine Merlin

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Transcriptional Auto-Regulation of RUNX1 P1 Promoter, Milka Martinez, Marcela Hinojosa, Daniel J. Trombly, Violeta Morin, Janet L. Stein, Gary S. Stein, Amjad Javed, and Soraya E. Gutierrez

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T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines, Janet E. McElhaney, George A. Kuchel, Xin Zhou, Susan L. Swain, and Laura Haynes

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Novel oral transforming growth factor-beta signaling inhibitor EW-7197 eradicates CML-initiating cells, Kazuhito Naka, Shaoguang Li, and Dae-Kee Kim

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A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling, Clíona Ní Cheallaigh, Jinhee Lee, Kim West, Nuria Martinez, Hardy Kornfeld, Douglas T. Golenbock, and Ed C. Lavelle

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Clinical expression of facioscapulohumeral muscular dystrophy in carriers of 1-3 D4Z4 reduced alleles: experience of the FSHD Italian National Registry, Ana Nikolic and Rossella Tupler

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Adapting Behavioral Interventions for Social Media Delivery, Sherry L. Pagoto, Molly E. Waring, Christine N. May, Eric Y. Ding, Werner H. Kunz, Rashelle B. Hayes, and Jessica L. Oleski

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How Would Children Register Their Own Births? Insights from a Survey of Students Regarding Birth Registration Knowledge and Policy Suggestions in Kenya, Matthew Pelowski, Richard G. Wamai, Joseph Wangombe, Hellen Nyakundi, Geofrey O. Oduwo, Benjamin K. Ngugi, and Javier Gordon Ogembo

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CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice, Alejandor Ramirez, Mary Dawn T. Co, and Anuja Mathew

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The carboxyl terminal mutational hotspot of the ciliary disease protein RPGRORF15 (retinitis pigmentosa GTPase regulator) is glutamylated in vivo, Kollu N. Rao, Manisha Anand, and Hemant Khanna

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Cardiovascular health awareness and the effect of an educational intervention on school-aged children in a rural district of India, Madhab Ray, Santanu Guha, Meghna Ray, Anita Kundu, Bipasha Ray, Kaushik Kundu, Santanu Goswami, Deepak Bhatt, Harry P. Selker, and Robert J. Goldberg

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Reconstruction of 60 Years of Chikungunya Epidemiology in the Philippines Demonstrates Episodic and Focal Transmission, Henrik Salje and Anon Srikiatkhachorn

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MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory, Alex Tek, Andrei A. Korostelev, and Samuel Coulbourn Flores

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Physical Activity-Related Policy and Environmental Strategies to Prevent Obesity in Rural Communities: A Systematic Review of the Literature, 2002-2013, M. Renée Umstattd Meyer, Cynthia K. Perry, Jasmin C. Sumrall, Megan S. Patterson, Shana M. Walsh, Stephanie C. Clendennen, Steven P. Hooker, Kelly R. Evenson, Karin V. Goins, Katie M. Heinrich, Nancy O'Hara Tompkins, Amy A. Eyler, Sydney Jones, Rachel Tabak, and Cheryl Valko

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Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress, Santiago Vernia, Caroline Morel, Joseph C. Madara, Julie Cavanagh-Kyros, Tamera Barrett, Kathryn O. Chase, Norman J. Kennedy, Dae Young Jung, Jason K. Kim, Neil Aronin, Richard A. Flavell, Bradford B. Lowell, and Roger J. Davis

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Improved cell metabolism prolongs photoreceptor survival upon retinal-pigmented epithelium loss in the sodium iodate induced model of geographic atrophy, Marina Zieger and Claudio Punzo

Publications from 2015

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The p53R172H Mutant Does Not Enhance Hepatocellular Carcinoma Development and Progression, Leanne G. Ahronian, David R. Driscoll, David S. Klimstra, and Brian C. Lewis

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The PsychENCODE project, Schahram Akbarian, Zhiping Weng, Eugenio Mattei, Michael Purcaro, Junko Tsuji, Geetha Senthil, Thomas Lehner, Pamela Sklar, Nenad Sestan, and PsychENCODE Consortium

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OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease, Thomas E. Akie, Lijun Liu, Minwoo Nam, Shi Lei, and Marcus P. Cooper

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Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation, Heather E. Arsenault, Jagoree Roy, Claudine E. Mapa, Martha S. Cyert, and Jennifer A. Benanti

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alphabeta T cell receptors as predictors of health and disease, Meriem Attaf, Eric Huseby, and Andrew K. Sewell

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DRC3 connects the N-DRC to dynein g to regulate flagellar waveform, Junya Awata, Kangkang Song, Jianfeng Lin, Stephen M. King, Michael J. Sanderson, Daniela Nicastro, and George B. Witman

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Using joint registry data from FORCE-TJR to improve the accuracy of risk-adjustment prediction models for thirty-day readmission after total hip replacement and total knee replacement, David C. Ayers, Thomas K. Fehring, Susan M. Odum, and Patricia D. Franklin

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Evaluating implementation of methicillin-resistant Staphylococcus aureus (MRSA) prevention guidelines in spinal cord injury centers using the PARIHS framework: a mixed methods study, Salva N. Balbale, Jennifer N. Hill, Marylou Guihan, Timothy P. Hogan, Kenzie A. Cameron, Barry Goldstein, and Charlesnika T. Evans

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The Resource Identification Initiative: A cultural shift in publishing, Anita Bandrowski, Matthew Brush, Jeffery S. Grethe, Melissa A. Haendel, David N. Kennedy, Sean Hill, Patrick R. Hof, Maryann E. Martone, Maaike Pols, Serena Tan, Nicole Washington, Elena Zudilova-Seinstra, and Nicole Vasilevsky

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Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells, Ahmet Rasim Barutcu, Bryan R. Lajoie, Rachel Patton McCord, Coralee E. Tye, Deli Hong, Terri L. Messier, Gillian Browne, Andre J. van Wijnen, Jane B. Lian, Janet L. Stein, Job Dekker, Anthony N. Imbalzano, and Gary S. Stein

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Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans, Lea M. Beaulieu, Lauren Clancy, Kahraman Tanriverdi, Emelia J. Benjamin, Carolyn D. Kramer, Ellen O. Weinberg, Xianbao He, Samrawit Mekasha, Eric O. Mick, Robin R. Ingalls, Caroline A. Genco, and Jane E. Freedman

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A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B, Aniuska Becerra-Artiles, Omar Dominguez-Amorocho, Lawrence J. Stern, and J. Mauricio Calvo-Calle

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Cognitive testing for dementia is adversely affected by administration in a foreign location, Cynthia Bechtel, Ruth Remington, Bruce A. Barton, Constance Barysauskas, and Thomas B. Shea

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The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer, Jon-Matthew Belton, Bryan R. Lajoie, Sylvain Audibert, Sylvain Cantaloube, Imen Lassadi, Isabelle Goiffon, Davide Bau, Marc A. Marti-Renom, Kerstin Bystricky, and Job Dekker

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Sequential dengue virus infections detected in active and passive surveillance programs in Thailand, 1994-2010, Piraya Bhoomiboonchoo, Ananda Nisalak, Natkamol Chansatiporn, In-Kyu Yoon, Siripen Kalayanarooj, Mathuros Thipayamongkolgul, Timothy Endy, Alan L. Rothman, Sharone Green, Anon Srikiatkhachorn, Darunee Buddhari, Mammen P. Mammen, and Robert V. Gibbons

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Glypican Is a Modulator of Netrin-Mediated Axon Guidance, Cassandra Blanchette, Paola N. Perrat, Andrea Thackeray, and Claire Y. Benard

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Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism, Charles Blatti, Majid Kazemian, Scot A. Wolfe, Michael H. Brodsky, and Saurabh Sinha

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Learning curves in emergency ultrasound education, David J. Blehar, Bruce A. Barton, and Romolo Joseph Gaspari

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FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons, Carles Bosch, Albert Martinez, Nuria Masachs, Catia M. Teixeira, Isabel Fernaud, Fausto Ulloa, Esther Perez-Martinez, Carlos Lois, Joan X. Comella, Javier DeFelipe, Angel Merchan-Perez, and Eduardo Soriano

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Health evaluation and referral assistant: a randomized controlled trial to improve smoking cessation among emergency department patients, Edwin D. Boudreaux, Beau Abar, Brianna Haskins, Brigitte Bauman, and Grant Grissom

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GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function, Alondra Schweizer Burguete, Sandra Almeida, Fen-Biao Gao, Robert Kalb, Michael R. Akins, and Nancy M. Bonini

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Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial, Gerd R. Burmester, William F. Rigby, Ronald F. van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ariella Kelman, Sophie Dimonaco, and Nina Mitchell

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Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo, Emerald Butko, Martin Distel, Claire Pouget, Bart Weijts, Isao Kobayashi, Kevin Ng, Christian Mosimann, Fabienne E. Poulain, Adam McPherson, Chih-Wen Ni, David L. Stachura, Natasha Del Cid, Raquel Espin-Palazon, Nathan D. Lawson, Richard Dorsky, Wilson K. Clements, and David Traver

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Biosimilars in rheumatology: what the clinician should know, Gilberto Castaneda-Hernandez, Rodrigo Gonzalez-Ramirez, Jonathan Kay, and Morton A. Scheinberg

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A Social-Ecological View of Barriers and Facilitators for HIV Treatment Adherence: Interviews with Puerto Rican HIV Patients, Eida M. Castro, Lydia E. Santiago, Julio C. Jimenez, Daira Davila-Vargas, and Milagros C. Rosal

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Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans, Can Cenik, Elif Sarinay Cenik, Gun W. Byeon, Fabian Grubert, Sophie I. Candille, Damek Spacek, Bilal Alsallakh, Hagen Tilgner, Carlos L. Araya, Hua Tang, Emiliano P. Ricci, and Michael P. Snyder

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Proyecto Mama: a lifestyle intervention in overweight and obese Hispanic women: a randomised controlled trial--study protocol, Lisa Chasan-Taber, Bess H. Marcus, Milagros C. Rosal, Katherine L. Tucker, Sheri J. Hartman, Penelope S. Pekow, Edward J. Stanek III, Barry Braun, Caren G. Solomon, JoAnne Manson, Sarah L. Goff, and Glenn Markenson

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Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation, Hui Cheng, Sha Hao, Yanfeng Liu, Yakun Pang, Shihui Ma, Fang Dong, Jing Xu, Guoguang Zheng, Shaoguang Li, Weiping Yuan, and Tao Cheng

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Decade-Long Trends in 30-Day Rehospitalization Rates After Acute Myocardial Infarction, Han-Yang Chen, Mayra Tisminetzky, Kate L. Lapane, Jorge L. Yarzebski, Sharina D. Person, Catarina I. Kiefe, Joel Gore, and Robert J. Goldberg

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Narratives to enhance smoking cessation interventions among African-American smokers, the ACCE project, Andrea Cherrington, Jessica H. Williams, Pamela Payne Foster, Heather L. Coley, Connie Kohler, Jeroan J. Allison, Catarina I. Kiefe, Julie E. Volkman, and Thomas K. Houston

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Hyperspectral Imaging as an Early Biomarker for Radiation Exposure and Microcirculatory Damage, Michael S. Chin, Brian B. Freniere, Luca Lancerotto, Jorge R. Lujan-Hernandez, Jonathan H. Saleeby, Yuan-Chyuan Lo, Dennis P. Orgill, Janice F. Lalikos, and Thomas J. Fitzgerald

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A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression, Hyoung-Soo Cho, HyunMu Shin, Helena Haberstock-Debic, Yan Xing, Timothy D. Owens, Jens Oliver. Funk, Ronald J. Hill, J. Michael Bradshaw, and Leslie J. Berg

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Inherited CHST11/MIR3922 deletion is associated with a novel recessive syndrome presenting with skeletal malformation and malignant lymphoproliferative disease, Sameer S. Chopra, Ignaty Leshchiner, Hatice Duzkale, Heather McLaughlin, Monica Giovanni, Chengsheng Zhang, Nathan Stitziel, Joyce D. Fingeroth, Robin M. Joyce, Matthew Lebo, Heidi Rehm, Dana Vuzman, Richard Maas, Shamil R. Sunyaev, Michael Murray, and Christopher A. Cassa

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Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs, Min-Te Chou, Bo W. Han, Chiung-Po Hsiao, Phillip D. Zamore, Zhiping Weng, and Jui-Hung Hung

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Impact on survival of the number of lymph nodes resected in patients with lymph node-negative gastric cancer, Xiaoyuan Chu and Zhongfa Yang

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Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics, Hannah Clapham, Derek A. Cummings, Ananda Nisalak, Siripen Kalayanarooj, Butsaya Thaisomboonsuk, Chonticha Klungthong, Stefan Fernandez, Anon Srikiatkhachorn, Louis R. Macareo, Justin Lessler, Julia Reiser, and In-Kyu Yoon

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Relationship among Glutamine, gamma-Aminobutyric Acid, and Social Cognition in Autism Spectrum Disorders, David E. Cochran, Elif M. Sikoglu, Steven M. Hodge, Richard A.E. Edden, Ann Foley, David N. Kennedy, Constance M. Moore, and Jean A. Frazier

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Improving patient notification of solid abdominal viscera incidental findings with a standardized protocol, Courtney E. Collins, Nicole Cherng, Theodore P. McDade, Babak Movahedi, Timothy A. Emhoff, Giles F. Whalen, Jennifer LaFemina, and Jon D. Dorfman

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Utilizing small nutrient compounds as enhancers of exercise-induced mitochondrial biogenesis, Daniel M. Craig, Stephen P. Ashcroft, Micah Y. Belew, Ben Stocks, Kevin Currell, Keith Baar, and Andrew Philp

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Reactive oxygen species in endothelial function - from disease to adaptation -, Siobhan M. Craige, Shashi Kant, and John F. Keaney Jr

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MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis, Timea Csak, Shashi Bala, Dora Lippai, Karen Kodys, Donna Catalano, Arvin Iracheta-Vellve, and Gyongyi Szabo

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Cotton rat immune responses to virus-like particles containing the pre-fusion form of respiratory syncytial virus fusion protein, Lori McGinnes Cullen, Jorge C. G. Blanco, and Trudy G. Morrison

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Characterization of functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in HIV-infected children and youth, Donna J. Curtis, Petronella Muresan, Sharon Nachman, Terence Fenton, Kelly M. Richardson, Teresa Dominguez, Patricia M. Flynn, Stephen A. Spector, Coleen K. Cunningham, Anthony Bloom, and Adriana Weinberg

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SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model, Xiaohua Dai, Jianbin Shen, Neeraja Priyanka Annam, Hong Jiang, Edi Levi, Charles M. Schworer, Gerard Tromp, Anandita Arora, Mary Higgins, Xiao-Fan Wang, Maozhou Yang, Hui J. Li, Kezhong Zhang, Helena Kuivaniemi, and Li Li

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Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues, Laura V. Danai, Rachel J. Roth Flach, Joseph V Virbasius, Lorena Garcia Menendez, Dae Young Jung, Jong Hun Kim, Jason K. Kim, and Michael P. Czech

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TRANSIT - A Software Tool for Himar1 TnSeq Analysis, Michael A. DeJesus, Chaitra Ambadipudi, Richard E. Baker, Christopher M. Sassetti, and Thomas R. Ioerger

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The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease, Xianjun Dong, Junko Tsuji, Adam Labadorf, Panos Roussos, Jiang-Fan Chen, Richard H. Myers, Schahram Akbarian, and Zhiping Weng

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Quantitative Correlation of in Vivo Properties with in Vitro Assay Results: The in Vitro Binding of a Biotin-DNA Analogue Modifier with Streptavidin Predicts the in Vivo Avidin-Induced Clearability of the Analogue-Modified Antibody, Shuping Dou, John Virostko, Dale L. Greiner, Alvin C. Powers, and Guozheng Liu

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Detecting Heart Failure Decompensation by Measuring Transthoracic Bioimpedance in the Outpatient Setting: Rationale and Design of the SENTINEL-HF Study, Silviu Dovancescu, Jane S. Saczynski, Chad E. Darling, Jarno Riistema, Fatima Sert Kuniyoshi, Theo E. Meyer, Robert J. Goldberg, and David D. McManus

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Ultrasonography of adnexal causes of acute pelvic pain in pre-menopausal non-pregnant women, Carolyn S. Dupuis and Young H. Kim

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A Prospective Controlled Trial of an Electronic Hand Hygiene Reminder System, Richard T. Ellison III, Constance Barysauskas, Elke A. Rundensteiner, Di Wang, and Bruce A. Barton

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Connecting Circadian Genes to Neurodegenerative Pathways in Fruit Flies, Patrick Emery

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Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors, David Ermert, Jutamas Shaughnessy, Thorsten Joeris, Jakub Kaplan, Catherine J. Pang, Evelyn A. Kurt-Jones, Peter A. Rice, Sanjay Ram, and Anna M. Blom

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Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture, Marta Esteves da Silva, Max Adrian, Philipp Schatzle, Joanna Lipka, Takuya Watanabe, Sukhee Cho, Kensuke Futai, Corette J. Wierenga, Lukas C. Kapitein, and Casper C. Hoogenraad

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FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1), Sandra J. Feeney, Meagan J. McGrath, Absorn Sriratana, Stefan M. Gehrig, Gordon S. Lynch, Colleen E. D'Arcy, John T. Price, Catriona A. McLean, Rossella Ginevra Tupler, and Christina A. Mitchell

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The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse, Francesca Finetti, Laura Patrussi, Donatella Galgano, Chiara Cassioli, Giuseppe Perinetti, Gregory J. Pazour, and Cosima T. Baldari

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Family Outbreaks of Nontyphoidal Salmonellosis following a Meal of Guinea Pigs, John B. Fournier, Kimberly Knox, Maureen Harris, and Michael Newstein