Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2014

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Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan, Ankita Bansal, Eun-Soo Kwon, Darryl Conte Jr., Haibo Liu, Michael J. Gilchrist, Lesley T. MacNeil, and Heidi A. Tissenbaum

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The relationship between subnormal peak-stimulated growth hormone levels and auxological characteristics in obese children, Jefferson Barrett, Louise S. Maranda, and Benjamin U. Nwosu

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Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast, Noah Dephoure, Sunyoung Hwang, Ciara O'Sullivan, Stacie E. Dodgson, Steven P. Gygi, Angelika Amon, and Eduardo M. Torres

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Arf4 is required for Mammalian development but dispensable for ciliary assembly, John A. Follit, Jovenal T. San Agustin, Julie A. Jonassen, Tingting Huang, Jaime A. Rivera-Perez, Kimberly D. Tremblay, and Gregory J. Pazour

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Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score, Keith A. A. Fox, Gordon FitzGerald, Etienne Puymirat, Wei Huang, Kathryn Carruthers, Tabassome Simon, Pierre Coste, Jacques Monsegu, Phillippe Gabriel Steg, Nicolas Danchin, and Frederick A. Anderson Jr.

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Upper extremity injury management by non-physician emergency practitioners in rural Uganda: A pilot study, Daniel S. Frank, Katie Dunleavy, Rashidah Nambaziira, Irene Nayebare, Bradley Dreifuss, and Mark Bisanzo

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Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters, Juan I. Fuxman Bass, Alex M. Tamburino, Akihiro Mori, Nathan Beittel, Matthew T. Weirauch, John S. Reece-Hoyes, and Albertha J. M. Walhout

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Fidelity of Histone Gene Regulation is Obligatory for Genome Replication and Stability, Prachi N. Ghule, Ronglin Xie, Ricardo F. Medina, Jennifer L. Colby, Stephen N. Jones, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein

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An improved predictive recognition model for Cys2-His2 zinc finger proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J. Keith Joung, Scot A. Wolfe, and Gary D. Stormo

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The comparative effectiveness of abatacept versus anti-tumour necrosis factor switching for rheumatoid arthritis patients previously treated with an anti-tumour necrosis factor, Leslie R. Harrold, George W. Reed, Joel M. Kremer, Jeffrey R. Curtis, Daniel H. Solomon, Marc C. Hochberg, and Jeffrey D. Greenberg

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Teaching tobacco dependence treatment and counseling skills during medical school: rationale and design of the Medical Students helping patients Quit tobacco (MSQuit) group randomized controlled trial, Rashelle B. Hayes, Alan C. Geller, Linda C. Churchill, Denise G. Jolicoeur, David M. Murray, Abigail Shobend, Sean P. David, Michael Adams, Kola Okuyemi, Randy Fauver, Robin Gross, Frank Leone, Rui Xiao, Jonathan Waugh, Sybil L. Crawford, and Judith K. Ockene

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Myogenic Enhancers Regulate Expression of the Facioscapulohumeral Muscular Dystrophy-Associated DUX4 Gene, Charis L. Himeda, Celine Debarnot, Sachiko Homma, Mary Lou Beermann, Jeffrey B. Miller, Peter L. Jones, and Takako I. Jones

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Rictor/mTORC2 Loss in the Myf5 Lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease, Chien-Min Hung, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Huawei Li, Clary B. Clish, Simone Hettmer, Amy J. Wagers, and David A. Guertin

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Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells, Nicola A. Kearns, Ryan M. J. Genga, Metewo Selase Enuameh, Manuel Garber, Scot A. Wolfe, and Rene Maehr

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Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors, Govind Kunduri, Changqing Yuan, Velayoudame Parthibane, Katherine M. Nyswaner, Ritu Kanwar, Kunio Nagashima, Steven G. Britt, Nickita Mehta, Varshika Kotu, Mindy Porterfield, Michael Tiemeyer, Patrick J. Dolph, Usha Acharya, and Jairaj K. Acharya

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The PPARgamma locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner, Scott E. LeBlanc, Qiong Wu, A. Rasim Barutcu, Hengyi Xiao, Yasuyuki Ohkawa, and Anthony N. Imbalzano

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Weight gain prevention in the school worksite setting: Results of a multi-level cluster randomized trial, Stephenie C. Lemon, Monica L. Wang, Nicole M. Wedick, Barbara Estabrook, Susan Druker, Kristin L. Schneider, Wenjun Li, and Lori Pbert

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Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6, Wan-Ju Liu, John S. Reece-Hoyes, Albertha J. M. Walhout, and David M. Eisenmann

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Sickle cell trait is not associated with endemic Burkitt lymphoma: an ethnicity and malaria endemicity-matched case-control study suggests factors controlling EBV may serve as a predictive biomarker for this pediatric cancer, David H. Mulama, Jeffrey A. Bailey, Joslyn Foley, Kiprotich Chelimo, Collins Ouma, Walter G.Z.O. Jura, Juliana A. Otieno, John M. Vulule, and Ann M. Moormann

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Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism, Ji Young Mun, Michael J. Previs, Hope Y. Yu, James Gulick, Larry S. Tobacman, Samantha Beck Previs, Jeffrey Robbins, David M. Warshaw, and Roger Craig

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The Effects of Vitamin D supplementation on Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Children and Adolescents with Vitamin D Deficiency and Either Type 1 or Type 2 Diabetes Mellitus, Benjamin U. Nwosu and Louise Maranda

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The Vitamin D Status of Prison Inmates, Benjamin U. Nwosu, Louise Maranda, Rosalie Berry, Barbara Colocino, Carlos D. Flores, Kerry Folkman, Thomas Groblewski, and Patricia Ruze

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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase beta and regulates complex V activity, Motiur Rahman, Niraj K. Nirala, Alka Singh, Lihua Julie Zhu, Kaori Taguchi, Takeshi Bamba, Eiichiro Fukusaki, Leslie M. Shaw, David G. Lambright, Jairaj K. Acharya, and Usha R. Acharya

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Smurf2 regulates hematopoietic stem cell self-renewal and aging, Charusheila Ramkumar, Yahui Kong, Sally E. Trabucco, Rachel M. Gerstein, and Hong Zhang

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Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cells, Raghavendra Pralhada Rao, Luana Scheffer, Sargur M. Srideshikan, Velayoudame Parthibane, Teresa Kosakowska-Cholody, M. Athar Masood, Kunio Nagashima, Prabhakar Gudla, Stephen Lockett, Usha Acharya, and Jairaj K. Acharya

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A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype, Ryan W. Serra, Minggang Fang, Sung Mi Park, Lloyd Hutchinson, and Michael R. Green

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A separable domain of the p150 subunit of human Chromatin Assembly Factor-1 promotes protein and chromosome associations with nucleoli, Corey L. Smith, Timothy D. Matheson, Daniel J. Trombly, Xiaoming Sun, Eric Campeau, Xuemei Han, John R. Yates III, and Paul D. Kaufman

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The Vitamin D Status in Inflammatory Bowel Disease, Lauren Veit, Louise Maranda, Jay G. Fong, and Benjamin U. Nwosu

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Targeted germ line disruptions reveal general and species-specific roles for paralog group 1 hox genes in zebrafish, Steven E. Weicksel, Ankit Gupta, Denise A. Zannino, Scot A. Wolfe, and Charles G. Sagerstrom

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Severity of Depressive Symptoms and Accuracy of Dietary Reporting among Obese Women with Major Depressive Disorder Seeking Weight Loss Treatment, Matthew C. Whited, Kristin L. Schneider, Bradley M. Appelhans, Yunsheng Ma, Molly E. Waring, Michele A. DeBiasse, Andrew M. Busch, Jessica L. Oleski, Philip A. Merriam, Barbara C. Olendzki, Sybil L. Crawford, Ira S. Ockene, Stephenie C. Lemon, and Sherry L. Pagoto

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Cluster-based Epidemic Control Through Smartphone-based Body Area Networks, Zhaoyang Zhang, Honggang Wang, Chonggang Wang, and Hua (Julia) Fang

Publications from 2013

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Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions, Nagesh R. Aragam, Kelly M. Thayer, Nabi Nge, Irving Hoffman, Francis Martinson, Debbie Kamwendo, Feng-Chang Lin, Colin Sutherland, Jeffrey A. Bailey, and Jonathan J. Juliano

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The phylogeny of permanent prostate brachytherapy, Jesse N. Aronowitz and Mark J. Rivard

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The role of emotional health in functional outcomes after orthopaedic surgery: extending the biopsychosocial model to orthopaedics: AOA critical issues, David C. Ayers, Patricia D. Franklin, and David C. Ring

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Patient-reported outcomes after total knee replacement vary on the basis of preoperative coexisting disease in the lumbar spine and other nonoperatively treated joints: the need for a musculoskeletal comorbidity index, David C. Ayers, Wenjun Li, Carol Oatis, Milagros C. Rosal, and Patricia D. Franklin

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Optimal electrocardiographic limb lead set for rapid emphysema screening, Rishi Bajaj, Lovely Chhabra, Zainab Basheer, and David H. Spodick

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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics, Desiree M. Baron, Laura J. Kaushansky, Catherine L. Ward, Reddy Ranjith Kumar Sama, Ru-ju Chian, Kristin J. Boggio, Alexandre J. C. Quaresma, Jeffrey A. Nickerson, and Daryl A. Bosco

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Social support and smoking abstinence among incarcerated adults in the United States: a longitudinal study, Beth Bock, Cheryl E. Lopes, Jacob J. van den Berg, Mary B. Roberts, L. A. R. Stein, Rosemarie A. Martin, Stephen A. Martin, and Jennifer G. Clarke

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Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in S. cerevisiae, Lars Boeckmann, Yoshimitsu Takahashi, Wei-Chun Au, Prashant K. Mishra, John S. Choy, Anthony R. Dawson, May Y. Szeto, Timothy J. Waybright, Christopher Heger, Christopher McAndrew, Paul K. Goldsmith, Timothy D. Veenstra, Richard E. Baker, and Munira A. Basrai

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Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1, Teresa J. Broering, Hongyan Wang, Naomi K. Boatright, Yang Wang, Katherine Baptista, Gilda Shayan, Kerry A. Garrity, Can Kayatekin, Daryl A. Bosco, C. Robert Matthews, Donna M. Ambrosino, Zuoshang Xu, and Gregory J. Babcock

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Factors influencing time to diagnosis and initiation of treatment of endemic Burkitt Lymphoma among children in Uganda and western Kenya: a cross-sectional survey, Geoffrey C. Buckle, Jennifer Pfau Collins, Peter Odada Sumba, Beccy Nakalema, Dorine Omenah, Kristine Stiffler, Corey Casper, Juliana A. Otieno, Jackson Orem, and Ann M. Moormann

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Innate sensing of chitin and chitosan, Chelsea L. Bueter, Charles A. Specht, and Stuart M. Levitz

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Serum cytokine profiles associated with specific adjuvants used in a DNA prime-protein boost vaccination strategy, Rachel Buglione-Corbett, Kimberly Lea Pouliot, Robyn Lynn Marty-Roix, Kim West, Shixia Wang, Egil Lien, and Shan Lu

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Physical activity and screen time in metabolically healthy obese phenotypes in adolescents and adults, Sarah M. Camhi, Molly E. Waring, Susan B. Sisson, Laura L. Hayman, and Aviva Must

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Writing is like touch, Lucy M. Candib

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The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS, Ci-Di Chen, Jacob A. Sloane, Hu Li, Nurgul Aytan, Eustathia Lela Giannaris, Ella Zeldich, Jason D. Hinman, Alpaslan Dedeoglu, Douglas L. Rosene, Rashmi Bansal, Jennifer I. Leubke, Makoto Kuro-o, and Carmela R. Abraham

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The impact of cardiac and noncardiac comorbidities on the short-term outcomes of patients hospitalized with acute myocardial infarction: a population-based perspective, Han-Yang Chen, Jane S. Saczynski, David D. McManus, Darleen M. Lessard, Jorge L. Yarzebski, Kate L. Lapane, Joel M. Gore, and Robert J. Goldberg

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Hdac6 regulates Tip60-p400 function in stem cells, Poshen B. Chen, Jui-Hung Hung, Taylor L. Hickman, Andrew H. Coles, James F. Carey, Zhiping Weng, Feixia Chu, and Thomas G. Fazzio

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Molecular signatures of chronic myeloid leukemia stem cells, Yaoyu Chen and Shaoguang Li

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p16 Stimulates CDC42-Dependent Migration of Hepatocellular Carcinoma Cells, Ya-Wen Chen, Hsiao-Chien Chu, Ze-Shiang Lin, Wei-Jyh Shiah, Chen-Pin Chou, David S. Klimstra, and Brian C. Lewis

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Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds, Jonathan J. Cherry, Erkan Y. Osman, Matthew C. Evans, Sungwoon Choi, Xuechao Xing, Gregory D. Cuny, Marcie A. Glicksman, Christian L. Lorson, and Elliot J. Androphy

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P-wave indices in patients with pulmonary emphysema: do P-terminal force and interatrial block have confounding effects, Lovely Chhabra, Vinod Chaubey, Chandrasekhar Kothagundla, Rishi Bajaj, Sudesh Kaul, and David H. Spodick

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Crosstalk between casein kinase II and Ste20-related kinase Nak1, Lubos Cipak, Sneha Gupta, Iva Rajovic, Quan-Wen Jin, Dorothea Anrather, Gustav Ammerer, Dannel McCollum, and Juraj Gregan

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When, Where and How Osteoporosis-Associated Fractures Occur: An Analysis from the Global Longitudinal Study of Osteoporosis in Women (GLOW), Aline G. Costa, Allison Wyman, Ethel S. Siris, Nelson B. Watts, Stuart Silverman, Kenneth G. Saag, Christian Roux, Maurizio Rossini, Johannes Pfeilschifter, Jeri W. Nieves, J. Coen Netelenbos, Lyn March, Andrea Z. LaCroix, Frederick H. Hooven, Susan L. Greenspan, Stephen H. Gehlbach, Adolfo Diez-Perez, Cyrus Cooper, Juliet E. Compston, Roland D. Chapurlat, Steven Boonen, Frederick A. Anderson Jr., Jonathan D. Adachi, and Silvano Adami

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Prenatal oral health education in U.S. dental schools and obstetrics and gynecology residencies, Megan Curtis, Hugh Silk, and Judith A. Savageau

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Adult Willingness to Use Email and Social Media for Peer-to-Peer Cancer Screening Communication: Quantitative Interview Study, Sarah L. Cutrona, Douglas W. Roblin, Joann L. Wagner, Bridget Gaglio, Andrew E. Williams, Rosalie A. Torres Stone, Terry S. Field, and Kathleen M. Mazor

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TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm, Alberto De Iaco, Federico A. Santoni, Anne Vannier, Michel Guipponi, Stylianos E. Antonarakis, and Jeremy Luban

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Using the bootstrap to establish statistical significance for relative validity comparisons among patient-reported outcome measures, Nina Deng, Jeroan J. Allison, Hua (Julia) Fang, Arlene S. Ash, and John E. Ware Jr.

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Healthcare seeking for diarrhoea, malaria and pneumonia among children in four poor rural districts in Sierra Leone in the context of free health care: results of a cross-sectional survey, Theresa Diaz, Asha S. George, Sowmya R. Rao, Peter S. Bangura, John B. Baimba, Shannon A. McMahon, and Augustin Kabano

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What Aspect of Dependence Does the Fagerström Test for Nicotine Dependence Measure?, Joseph R. DiFranza, Robert J. Wellman, Judith A. Savageau, Ariel Beccia, W. W. Sanouri A. Ursprung, and Robert McMillen

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Temporal regulation of nuclear factor one occupancy by calcineurin/NFAT governs a voltage-sensitive developmental switch in late maturing neurons, Baojin Ding, Wei Wang, Tharakeswari Selvakumar, Hualin Simon Xi, Hong Zhu, Chi-Wing Chow, Jay D. Horton, Richard M. Gronostajski, and Daniel L. Kilpatrick

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Volume Modulated Arc Therapy (VMAT) for pulmonary Stereotactic Body Radiotherapy (SBRT) in patients with lesions in close approximation to the chest wall, Linda Ding, Yuan-Chyuan Lo, Sidney P. Kadish, David C. Goff Jr., Richard S. Pieters, Geoffrey Graeber, Karl Uy, Syed Quadri, Richard P. Moser, Kevin Martin, John Day, and Thomas J. Fitzgerald

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Monoaminergic orchestration of motor programs in a complex C. elegans behavior, Jamie L. Donnelly, Christopher M. Clark, Andrew M. Leifer, Jennifer K. Pirri, Marian Haburcak, Michael M. Francis, Aravinthan D. T. Samuel, and Mark J. Alkema

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Intraperitoneal Injection is Not Always a Suitable Alternative to Intravenous Injection for Radiotherapy, Shuping Dou, Miles Smith, Yuzhen Wang, Mary Rusckowski, and Guozheng Liu

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Sex differences in circumstances and consequences of outdoor and indoor falls in older adults in the MOBILIZE Boston cohort study, Rachel Duckham, Elizabeth Procter-Gray, Marian T. Hannan, Suzanne G. Leveille, Lewis A. Lipsitz, and Wenjun Li

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Racial and ethnic differences in primary, unscheduled cesarean deliveries among low-risk primiparous women at an academic medical center: a retrospective cohort study, Joyce K. Edmonds, Revital Yehezkel, Xun Liao, and Tiffany A. Moore Simas

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MEN1 is a Melanoma Tumor Suppressor that Preserves Genomic Integrity by Stimulating Transcription of Genes that Promote Homologous Recombination-Directed DNA Repair, Minggang Fang, Fen Xia, Meera Mahalingam, Ching-Man A. Virbasius, Narendra Wajapeyee, and Michael R. Green

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Human papillomavirus E7 induces rereplication in response to DNA damage, Xueli Fan, Yingwang Liu, Susan Ann Heilman, and Jason J. Chen

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Future vision for the quality assurance of oncology clinical trials, Thomas J. Fitzgerald, Maryann Bishop-Jodoin, Walter R. Bosch, Walter J. Curran, David S. Followill, James M. Galvin, Richard Hanusik, Steven R. King, Michael V. Knopp, Fran Laurie, Elizabeth O'Mear, Jeff M. Michalski, Joel H. Saltz, Mitchell D. Schnall, Lawrence Schwartz, Kenneth Ulin, Ying Xiao, and Marcia Urie

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Sustaining remission of psychotic depression: rationale, design and methodology of STOP-PD II, Alastair J. Flint, Barnett S. Meyers, Anthony J. Rothschild, Ellen M. Whyte, Benoit H. Mulsant, Matthew V. Rudorfer, Patricia Marino, and STOP-PD II Study Group

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Specific trans-synaptic interaction with inhibitory interneuronal neurexin underlies differential ability of neuroligins to induce functional inhibitory synapses, Kensuke Futai, Christopher D. Doty, Brian Baek, Jubin Ryu, and Morgan Sheng

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GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation, Hira Lal Goel, Bryan M. Pursell, Cheng Chang, Leslie M. Shaw, Junhao Mao, Karl Simin, Prashant Kumar, Craig W. Vander Kooi, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Charlotte Kuperwasser, and Arthur M. Mercurio

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IDEAS for a healthy baby--reducing disparities in use of publicly reported quality data: study protocol for a randomized controlled trial, Sarah L. Goff, Penelope S. Pekow, Katharine O. White, Tara Lagu, Kathleen M. Mazor, and Peter K. Lindenauer

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A case-control study of physical activity patterns and risk of non-fatal myocardial infarction, Jian Gong, Hannia Campos, Joseph Mark A. Fiecas, Stephen T. McGarvey, Robert J. Goldberg, Caroline Richardson, and Ana Baylin

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A thromboembolic model for the efficacy and safety evaluation of combined mechanical and pharmacologic revascularization strategies, Matthew J. Gounis, Raul G. Nogueira, Manik Mehra, Juyu Chueh, and Ajay K. Wakhloo

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Sub-millisecond time-resolved SAXS using a continuous-flow mixer and X-ray micro-beam, Rita Graceffa, Robert P. Nobrega, Raul Barrea, Sagar V. Kathuria, Srinivas Chakravarthy, Osman Bilsel, and Thomas Irving

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Cognitive impairment and self-care in heart failure, Alexandra M. Hajduk, Stephenie C. Lemon, David D. McManus, Darleen M. Lessard, Jerry H. Gurwitz, Frederick A. Spencer, Robert J. Goldberg, and Jane S. Saczynski

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Theranostic Upconversion Nanoparticles (II), Gang Han and Guanying Chen

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Laxative use and incident falls, fractures and change in bone mineral density in postmenopausal women: results from the Women's Health Initiative, Bernhard Haring, Mary B. Pettinger, Jennifer W. Bea, Jean Wactawski-Wende, Ryan M. Carnahan, Judith K. Ockene, Moritz Wyler von Ballmoos, Robert B. Wallace, and Sylvia Wassertheil-Smoller

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One among many: ODF2 isoform 9, a.k.a. Cenexin-1, is required for ciliogenesis, Heidi Hehnly, Hui-Fan Hung, and Stephen J. Doxsey

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Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence, Linzy M. Hendrickson, Melissa Guildford, and Andrew R. Tapper

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The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state, J. Manuel Hernandez-Hernandez, Chandrashekara Mallappa, Brian T. Nasipak, Steffi Oesterreich, and Anthony N. Imbalzano

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Pax3 synergizes with Gli2 and Zic1 in transactivating the Myf5 epaxial somite enhancer, Charis Himeda, Marietta V. Barro, and Charles P. Emerson Jr.

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Cluster-randomized trial of a web-assisted tobacco quality improvement intervention of subsequent patient tobacco product use: A national dental PBRN study, Thomas K. Houston, Kathryn L. Delaughter, Midge N. Ray, Gregg H. Gilbert, Jeroan J. Allison, Catarina I. Kiefe, and Julie E. Volkman

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Progressive levels of physical dependence to tobacco coincide with changes in the anterior cingulum bundle microstructure, Wei Huang, Joseph R. DiFranza, David N. Kennedy, Nanyin Zhang, Douglas M. Ziedonis, W. W. Sanouri A. Ursprung, and Jean A. King

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Genetic modification of the association between peripubertal dioxin exposure and pubertal onset in a cohort of Russian boys, Olivier Humblet, Susan A. Korrick, Paige L. Williams, Oleg Sergeyev, Claude Emond, Linda S. Birnbaum, Jane S. Burns, Larisa Altshul, Donald G. Patterson Jr., Wayman E. Turner, Mary M. Lee, Boris Revich, and Russ Hauser

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Prmt7 is dispensable in tissue culture models for adipogenic differentiation, Yu-Jie Hu, Said Sif, and Anthony N. Imbalzano

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BRG1, a SWI/SNF chromatin remodeling enzyme ATPase, is required for maintenance of nuclear shape and integrity, Anthony N. Imbalzano, Karen M. Imbalzano, and Jeffrey A. Nickerson

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Nuclear Shape Changes Are Induced by Knockdown of the SWI/SNF ATPase BRG1 and Are Independent of Cytoskeletal Connections, Karen M. Imbalzano, Nathalie Cohet, Qiong Wu, Jean M. Underwood, Anthony N. Imbalzano, and Jeffrey A. Nickerson

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U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs, Jermaine L. Jenkins, Anant A. Agrawal, Ankit Gupta, Michael R. Green, and Clara L. Kielkopf

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Activation of mammalian target of rapamycin mediates rat pain-related responses induced by BmK I, a sodium channel-specific modulator, Feng Jiang, Xue-Yan Pang, Qing-Shan Niu, Li-Ming Hua, Ming Cheng, and Yong-Hua Ji

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Latent effects of Hsp90 mutants revealed at reduced expression levels, Li Jiang, Parul Mishra, Ryan T. Hietpas, Konstantin B. Zeldovich, and Daniel N. A. Bolon

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Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleo-cytoplasmic shuttling, Baowei Jiao, Naoko Taniguchi-Ishigaki, Cenap Gungor, Marvin A. Peters, Ya-Wen Chen, Sabine Riethdorf, Alexander Drung, Leanne G. Ahronian, JongDae Shin, Rachna Pagnis, Klaus Pantel, Taro Tachibana, Brian C. Lewis, Steven A. Johnsen, and Ingolf Bach

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Trends in the medical management of patients with heart failure, Samuel W. Joffe, Matthew DeWolf, Jeffrey Shih, David D. McManus, Frederick A. Spencer, Darleen M. Lessard, Joel M. Gore, and Robert J. Goldberg

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Improved survival after heart failure: a community-based perspective, Samuel W. Joffe, Kristy T. Webster, David D. McManus, Michael S. Kiernan, Darleen M. Lessard, Jorge L. Yarzebski, Chad E. Darling, Joel M. Gore, and Robert J. Goldberg

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A specific family of interspersed repeats (SINEs) facilitates meiotic synapsis in mammals, Matthew E. Johnson, Ross A. Rowsey, Sofia Shirley, Catherine Vandevoort, Jeffrey A. Bailey, and Terry Hassold

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Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope, Vahbiz Jokhi, James A. Ashley, John J. Nunnari, Akiko Noma, Naoto ito, Noriko Wakabayashi-Ito, Melissa J. Moore, and Vivian Budnik

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Growing impact of restenosis on the surgical treatment of peripheral arterial disease, Douglas W. Jones, Andres Schanzer, Yuanyuan Zhao, Todd A. MacKenzie, Brian W. Nolan, Michael S. Conte, Philip P. Goodney, and Vascular Study Group of New England

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KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance, Dae Young Jung, UmaDevi Chalasani, Ning Pan, Randall H. Friedline, Domenick A. Prosdocimo, Minwoo Nam, Yoshihiro Azuma, Rajanikanth Maganti, Kristine Yu, Ashish Velagapudi, Bryan O'Sullivan-Murphy, Juliano L. Sartoretto, Mukesh K. Jain, Marcus P. Cooper, Fumihiko Urano, Jason K. Kim, and Susan Gray

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Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity, Shashi Kant, Tamera Barrett, Anastassiia Vertii, Yun Hee Noh, Dae Young Jung, Jason K. Kim, and Roger J. Davis