Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2016

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Regulatory T Cells in Endemic Burkitt Lymphoma Patients Are Associated with Poor Outcomes: A Prospective, Longitudinal Study, Emily Parsons, Juliana A. Otieno, John Michael Ong'echa, Christina E. Nixon, John Vulule, Christian Munz, V. Ann Stewart, and Ann M. Moormann

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Newer Oral Anticoagulants: Stroke Prevention and Pitfalls, Anand Patel, Richard P. Goddeau, and Nils Henninger

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Unilateral Eye Findings: A Rare Herald of Acute Leukemia, Avni V. Patel, John B. Miller, Rajneesh Nath, Helen A. Shih, Michael K. Yoon, Suzanne K. Freitag, George Papaliodis, Teresa C. Chen, Dean Eliott, and Ivana K. Kim

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The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L, Victoria E. Pedanou, Stephane Gobeil, Sebastien Tabaries, Tessa M. Simone, Lihua Julie Zhu, Peter M. Siegel, and Michael R. Green

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How Would Children Register Their Own Births? Insights from a Survey of Students Regarding Birth Registration Knowledge and Policy Suggestions in Kenya, Matthew Pelowski, Richard G. Wamai, Joseph Wangombe, Hellen Nyakundi, Geofrey O. Oduwo, Benjamin K. Ngugi, and Javier Gordon Ogembo

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Gene therapy approaches for the treatment of retinal disorders, Lolita Petit and Claudio Punzo

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Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI, Susanne Pfeiler, Eicke Latz, and Bernd Engelmann

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Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells, Lana M. Pollock, Nilay Gupta, Xi Chen, Elizabeth J. Luna, and Brian M. McDermott Jr (PloS one)

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Preparing Future Leaders: An Integrated Quality Improvement Residency Curriculum, Stacy E. Potts, Sara G. Shields, and Carole C. Upshur

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Endothelial-specific inhibition of NF-kappaB enhances functional haematopoiesis, Michael G. Poulos, Pradeep Ramalingam, Michael C. Gutkin, Maria Kleppe, Michael Ginsberg, Michael J. P. Crowley, Olivier Elemento, Ross L. Levine, Shahin Rafii, Jan Kitajewski, Matthew B. Greenblatt, Jae-Hyuck Shim, and Jason M. Butler

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Multimodal Learning and Intelligent Prediction of Symptom Development in Individual Parkinson's Patients, Andrzej W. Przybyszewski, Mark Kon, Stanislaw Szlufik, Artur Szymanski, Piotr Habela, and Dariusz M. Koziorowski

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Surveillance Immunity: An Emerging Paradigm of Innate Defense Activation in Caenorhabditis elegans, Read Pukkila-Worley

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CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice, Alejandor Ramirez, Mary Dawn T. Co, and Anuja Mathew

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Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development, Kasmir Ramo, Koichi Sugamura, Siobhan M. Craige, John F. Keaney Jr., and Roger J. Davis

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The carboxyl terminal mutational hotspot of the ciliary disease protein RPGRORF15 (retinitis pigmentosa GTPase regulator) is glutamylated in vivo, Kollu N. Rao, Manisha Anand, and Hemant Khanna

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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation, Dmitry Ratner, M. Pontus A. Orning, Megan K. Proulx, Donghai Wang, Mikhail A. Gavrilin, Mark D. Wewers, Emad S. Alnemri, Peter F. Johnson, Bettina Lee, Joan Mecsas, Nobuhiko Kayagaki, Jon D. Goguen, and Egil Lien

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Cardiovascular health awareness and the effect of an educational intervention on school-aged children in a rural district of India, Madhab Ray, Santanu Guha, Meghna Ray, Anita Kundu, Bipasha Ray, Kaushik Kundu, Santanu Goswami, Deepak Bhatt, Harry P. Selker, and Robert J. Goldberg

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Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS, Line S. Reinert, Katarina Lopusna, Henriette Winther, Chenglong Sun, Martin K. Thomsen, Ramya Nandakumar, Trine H. Mogensen, Morten Meyer, Christian Vaegter, Jens R. Nyengaard, Katherine A. Fitzgerald, and Soren R. Paludan

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A novel clinical tool to classify facioscapulohumeral muscular dystrophy phenotypes, Giulia Ricci and Rossella Ginevra Tupler

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Patient prioritization of comorbid chronic conditions in the Veteran population: Implications for patient-centered care, Lorilei M. Richardson, Jennifer N. Hill, Bridget M. Smith, Erica D. Bauer, Frances M. Weaver, Howard S. Gordon, Kevin T. Stroupe, and Timothy P. Hogan

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The E-Coach technology-assisted care transition system: a pragmatic randomized trial, Christine S. Ritchie, Thomas K. Houston, Joshua S. Richman, Heather J. Sobko, Eta S. Berner, Benjamin B. Taylor, Amanda H. Salanitro, and Julie L. Locher

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Cancer of the uterus and treatment of stress incontinence: a pilot study, Katina Robison, Elizabeth Lokich, Sonali Raman, Christine Luis, Christina Raker, Melissa A. Clark, and Kyle Wohlrab

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Defining an International Standard Set of Outcome Measures for Patients With Hip or Knee Osteoarthritis: Consensus of the International Consortium for Health Outcomes Measurement Hip and Knee Osteoarthritis Working Group, Ola Rolfson, David C. Ayers, and Patricia D. Franklin

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Fresh Start, a postpartum weight loss intervention for diverse low-income women: design and methods for a randomized clinical trial, Milagros C. Rosal, Christina Haughton, Barbara Estabrook, Monica L. Wang, German Chiriboga, Oahn H.T. Nguyen, Sharina D. Person, and Stephenie C. Lemon

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Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia, Rachel J. Roth Flach, Laura V. Danai, Marina DiStefano, Mark Kelly, Lorena Garcia Menendez, Agata Jurczyk, Rohit B. Sharma, Dae Young Jung, Jong Hun Kim, Jason K. Kim, Rita Bortell, Laura C. Alonso, and Michael P. Czech

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Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function, Rachel J. Roth Flach, Chang-An Guo, Laura V. Danai, Joseph C. Yawe, Sharvari Gujja, Yvonne J.K. Edwards, and Michael P. Czech

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Impact of a family medicine resident wellness curriculum: a feasibility study, Christine Runyan, Judith A. Savageau, Stacy E. Potts, and Linda F. Weinreb

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Reconstruction of 60 Years of Chikungunya Epidemiology in the Philippines Demonstrates Episodic and Focal Transmission, Henrik Salje and Anon Srikiatkhachorn

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An exploration of the role of religion/spirituality in the promotion of physicians' wellbeing in Emergency Medicine, Elena Salmoirago-Blotcher, George Fitchett, Katherine Leung, Gregory A. Volturo, Edwin D. Boudreaux, Sybil L. Crawford, Ira S. Ockene, and Farr Curlin

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Activation of WNT/beta-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61, Makoto Sano, David R. Driscoll, Wilfredo E. De Jesus-Monge, Brian J. Quattrochi, Victoria A. Appleman, Jianhong Ou, Lihua (Julie) Zhu, and Brian C. Lewis

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Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion, David E. Saslowsky, Jay R. Thiagarajah, Beth A. McCormick, Jean C. Lee, and Wayne I. Lencer

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beta1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation, Aejaz Sayeed, Huimin Lu, Qin Liu, David Deming Ii, Alexander Duffy, Peter McCue, Adam P. Dicker, Roger J. Davis, Dmitry Gabrilovich, Ulrich Rodeck, Dario C. Altieri, and Lucia R. Languino

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Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression, Dorothy P. Schafer, Christopher T. Heller, Georgia Gunner, Molly Heller, Christopher Gordon, Timothy Hammond, Yochai Wolf, Steffen Jung, and Beth Stevens

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Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group, L. Schmaal, M. Rose, and ENIGMA-Major Depressive Disorder Working Group

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Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo, Alexandra L. Schober, Dmitriy A. Gagarkin, Ying Chen, Guangping Gao, Lauren Jacobson, and Alexander A. Mongin

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Twenty-Five Year Secular Trends in Lipids and Modifiable Risk Factors in a Population-Based Biracial Cohort: The Coronary Artery Risk Development in Young Adults (CARDIA) Study, 1985-2011, Pamela J. Schreiner, David R. Jacobs Jr, Nathan D. Wong, and Catarina I. Kiefe

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Tanning bed burns reported on Twitter: over 15,000 in 2013, Andrew B. Seidenberg, Sherry L. Pagoto, Theodore A. Vickey, Eleni Linos, Mackenzie R. Wehner, Renata Dalla Costa, and Alan C. Geller

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Performance of rapid SOFIA Influenza A+B test compared to Luminex x-TAG respiratory viral panel assay in the diagnosis of influenza A, B, and subtype H3, William Selove and Lokinendi V. Rao

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Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources, Ravi Shah, Kahraman Tanriverdi, Daniel Levy, Martin Larson, Mark B. Gerstein, Eric O. Mick, Joel Rozowsky, Robert Kitchen, Venkatesh Murthy, Ekaterina Mikalev, and Jane E. Freedman

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IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis, Anita T. Shaw, Yukiko Maeda, and Ellen M. Gravallese

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Impaired neurodevelopment by the low complexity domain of CPEB4 reveals a convergent pathway with neurodegeneration, Jihae Shin, Johnny S. Salameh, and Joel D. Richter

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Neural Integration Underlying a Time-Compensated Sun Compass in the Migratory Monarch Butterfly, Eli Shlizerman, James Phillips-Portillo, Daniel B. Forger, and Steven M. Reppert

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Neighborhood environment correlates of physical activity and sedentary behavior among Latino adults in Massachusetts, Valerie J. Silfee, Milagros C. Rosal, Meera Sreedhara, Vilma Lora, and Stephenie C. Lemon

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Listening for Grace, Hugh Silk

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Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability, M. Catarina Silva, Sandra Almeida, Md Helal Uddin Biswas, Zhijun Zhang, Fen-Biao Gao, and Stephen J. Haggarty

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Patient-Facing Mobile Apps to Treat High-Need, High-Cost Populations: A Scoping Review, Karandeep Singh, Kaitlin Drouin, Lisa P. Newmark, Malina Filkins, Elizabeth Silvers, Paul A. Bain, Donna M. Zulman, Jae-Ho Lee, Ronen Rozenblum, Erika Pabo, Adam Landman, Elissa V. Klinger, and David W. Bates

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Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype, Clare M. Smith, Megan K. Proulx, Andrew J. Olive, Dominick Laddy, Bibhuti B. Mishra, Caitlin Moss, Nuria Martinez, Michelle M. Bellerose, Palmira Barreira-Silva, Jia Yao Phuah, Richard E. Baker, Samuel M. Behar, Hardy Kornfeld, Thomas G. Evans, Gillian Beamer, and Christopher M. Sassetti

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One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation, Jordan L. Smith, Liam C. Lee, Abigail Read, Qiuning Li, Bing Yu, Chih-Shia Lee, and Ji Luo

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Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation, Lorissa J. Smulan, Wei Ding, Elizaveta Freinkman, Sharvari Gujja, Yvonne J. Edwards K, and Amy K. Walker

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Prevention of sexual transmission of Ebola in Liberia through a national semen testing and counselling programme for survivors: an analysis of Ebola virus RNA results and behavioural data, Moses J. Soka, Mary J. Choi, Christine Wasunna, and Jeffrey A. Bailey

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High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program, Apurv Soni, Allison Earon, Anna Handorf, Nisha Fahey, Kandarp Talati, John Bostrom, Ki Chon, Craig Napolitano, Michael S. Chin, John Stephen Sullivan, Shyamsundar Raithatha, Robert J. Goldberg, Somashekhar Nimbalkar, Jeroan J. Allison, Sunil Thanvi, and David D. McManus

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Association of common mental disorder symptoms with health and healthcare factors among women in rural western India: results of a cross-sectional survey, Apurv Soni, Nisha Fahey, Nancy Byatt, Anusha Prabhakaran, Tiffany A. Moore Simas, Jagdish Vankar, Ajay Phatak, Eileen O'Keefe, Jeroan J. Allison, and Somashekhar Nimbalkar

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Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages, Ernesto R. Soto, Olivia O'Connell, Fusun Dikengil, Paul J. Peters, Paul R. Clapham, and Gary R. Ostroff

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Common Statistical Pitfalls in Basic Science Research, Lisa M. Sullivan, Janice Weinberg, and John F. Keaney Jr.

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A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes, Elliot W. Swartz, Jaeyun Baek, Mochtar Pribadi, Kevin J. Wojta, Sandra Almeida, Anna M. Karydas, Fen-Biao Gao, Bruce L. Miller, and Giovanni Coppola

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Longitudinal changes in the dietary inflammatory index: an assessment of the inflammatory potential of diet over time in postmenopausal women, F. K. Tabung, S. E. Steck, J. Zhang, Yunsheng Ma, A. D. Liese, F. A. Tylavsky, M. Z. Vitolins, Judith K. Ockene, and J. R. Hebert

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Patient-Specific MRI-Based Right Ventricle Models Using Different Zero-Load Diastole and Systole Geometries for Better Cardiac Stress and Strain Calculations and Pulmonary Valve Replacement Surgical Outcome Predictions, Dalin Tang, Pedro J. del Nido, Chun Yang, Heng Zuo, Xueying Huang, Rahul H. Rathod, Vasu Gooty, Alexander Tang, Zheyang Wu, Kristen L. Billiar, and Tal Geva

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Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism, Yuefeng Tang, Martina Wallace, Joan Sanchez-Gurmaches, Wen-Yu Hsiao, Huawei Li, Peter L. Lee, Santiago Vernia, Christian M. Metallo, and David A. Guertin

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Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition, Michelle D. Tate, James D.H. Ong, Jennifer K. Dowling, Julie L. McAuley, Avril B. Robertson, Eicke Latz, Grant R. Drummond, Matthew A. Cooper, Paul J. Hertzog, and Ashley Mansell

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MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory, Alex Tek, Andrei A. Korostelev, and Samuel Coulbourn Flores

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Endotracheal Tube Cuff Pressures in Patients Intubated Prior to Helicopter EMS Transport, Joseph Tennyson, Tucker Ford-Webb, Stacy Weisberg, and Donald LeBlanc

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Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection, Donald J. Tipper and Eva Szomolanyi-Tsuda

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A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization, Shira Toledano, Huayi Lu, Agustina Palacio, Keren Ziv, Ofra Kessler, Shlomit Schaal, Gera Neufeld, and Yoreh Barak

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No current evidence for widespread dosage compensation in S. cerevisiae, Eduardo M. Torres, Michael Springer, and Angelika Amon

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DNApi: A De Novo Adapter Prediction Algorithm for Small RNA Sequencing Data, Junko Tsuji and Zhiping Weng

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Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia, Artsiom Tsyrkunou, Sarika Agarwal, Bibek Koirala, Robert W. Finberg, Rajneesh Nath, Bruce A. Barton, Stuart M. Levitz, Jennifer P. Wang, and Sanjay Ram

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A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection, Te-Chen Tzeng, Stefan A. Schattgen, Brian G. Monks, Donghai Wang, Anna M. Cerny, Eicke Latz, Katherine A. Fitzgerald, and Douglas T. Golenbock

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Physical Activity-Related Policy and Environmental Strategies to Prevent Obesity in Rural Communities: A Systematic Review of the Literature, 2002-2013, M. Renée Umstattd Meyer, Cynthia K. Perry, Jasmin C. Sumrall, Megan S. Patterson, Shana M. Walsh, Stephanie C. Clendennen, Steven P. Hooker, Kelly R. Evenson, Karin V. Goins, Katie M. Heinrich, Nancy O'Hara Tompkins, Amy A. Eyler, Sydney Jones, Rachel Tabak, and Cheryl Valko

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Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans, Rajendra Upadhya, Woei C. Lam, Brian Maybruck, Charles A. Specht, Stuart M. Levitz, and Jennifer K. Lodge

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Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity, Tara Vanderweyde, John D. Leszyk, and Benjamin Wolozin

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Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling, Jennifer J. VanOudenhove, Ricardo F. Medina, Prachi N. Ghule University of Vermont College of Medicine, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi, and Gary S. Stein

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Dynamics of Nucleosome Positioning Maturation following Genomic Replication, Pauline Vasseur, Saphia Tonazzini, Rahima Ziane, Alain Camasses, Oliver J. Rando, and Marta Radman-Livaja

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An alternative splicing program promotes adipose tissue thermogenesis, Santiago Vernia, Yvonne J. K. Edwards, Myoung Souk Han, Julie Cavanagh-Kyros, Tamera Barrett, Jason K. Kim, and Roger J. Davis

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Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress, Santiago Vernia, Caroline Morel, Joseph C. Madara, Julie Cavanagh-Kyros, Tamera Barrett, Kathryn O. Chase, Norman J. Kennedy, Dae Young Jung, Jason K. Kim, Neil Aronin, Richard A. Flavell, Bradford B. Lowell, and Roger J. Davis

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Human basal body basics, Anastassiia Vertii, Hui-Fang Hung, Heidi Hehnly, and Stephen J. Doxsey

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NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-kappaB-Dependent and -Independent Functions, Katerina Vlantis, Andy Wullaert, Apostolos Polykratis, Vangelis Kondylis, Marius Dannappel, Robin Schwarzer, Patrick Welz, Teresa Corona, Henning Walczak, Falk Weih, Ulf Klein, Michelle Kelliher, and Manolis Pasparakis

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Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice, Petr Vodicka, Kathryn O. Chase, Maria Iuliano, Adelaide Tousley, Dana T. Valentine, Ellen Sapp, Kimberly B. Kegel-Gleason, Miguel Sena-Esteves, Neil Aronin, and Marian DiFiglia

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Regulation of X-linked gene expression during early mouse development by Rlim, Feng Wang, JongDae Shin, Jeremy Shea, Jun Yu, Ana Boskovic, Meg Byron, Xiaochun Zhu, Alex K. Shalek, Aviv Regev, Jeanne B. Lawrence, Eduardo M. Torres, Lihua J. Zhu, Oliver J. Rando, and Ingolf Bach

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Design and methods for a community-based intervention to reduce sugar-sweetened beverage consumption among youth: H2GO! study, Monica L. Wang, Stephenie C. Lemon, Kristian Clausen, Julie Whyte, and Milagros C. Rosal

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Metagenomic Sequencing with Strain-Level Resolution Implicates Uropathogenic E. coli in Necrotizing Enterocolitis and Mortality in Preterm Infants, Doyle V. Ward, Matthias Scholz, Moreno Zolfo, Diana H. Taft, Kurt R. Schibler, Adrian Tett, Nicola Segata, and Ardythe L. Morrow

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Standardizing disease-specific quality of life measures across multiple chronic conditions: development and initial evaluation of the QOL Disease Impact Scale (QDIS(R)), John E. Ware Jr., Barbara Gandek, Rick Guyer, and Nina Deng

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Interest in a Twitter-delivered weight loss program among women of childbearing age, Molly E. Waring, Kristin L. Schneider, Bradley M. Appelhans, Tiffany A. Moore Simas, Rui Xiao, Matthew C. Whited, Andrew M. Busch, Martinus M. Evans, and Sherry L. Pagoto

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Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans, Emma Watson, Viridiana Olin-Sandoval, Michael J. Hoy, Chi-Hua Li, Timo Louisse, Victoria Yao, Akihiro Mori, Amy D. Holdorf, Olga G. Troyanskaya, Markus Ralser, and Albertha J. M. Walhout

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Society of Behavioral Medicine supports implementation of high quality lung cancer screening in high-risk populations, Karriem S. Watson, Amanda C. Blok, Joanna Buscemi, Yamile Molina, Marian Fitzgibbon, Melissa A. Simon, Lance Williams, Kameron Matthews, Jamie L. Studts, Sarah E. Lillie, Jamie S. Ostroff, Lisa Carter-Harris, and Robert A. Winn

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ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis, Jessica L. Weatherbee, Jean-Louis Kraus, and Alonzo H. Ross

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Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood-Onset Retinal Dystrophy, Richard G. Weleber, Mark E. Pennesi, David J. Wilson, Shalesh Kaushal, Laura R. Erker, Lauren Jensen, Maureen T. McBride, Terence R. Flotte, Margaret Humphries, Roberto Calcedo, William W. Hauswirth, Jeffrey D. Chulay, and J. Timothy Stout

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Trajectories of functional decline in knee osteoarthritis: the Osteoarthritis Initiative, Daniel K. White, Tuhina Neogi, Uyen Sa D. T. Nguyen, Jingbo Niu, and Yuqing Zhang

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CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia, Kelly L. Williams, Jason Kost, Robert H. Brown Jr., John E. Landers, and Ian P. Blair

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PI3-kinase mutation linked to insulin and growth factor resistance in vivo, Jonathon N. Winnay, Marie H. Solheim, Ercument Dirice, Masaji Sakaguchi, Hye Lim Noh, Hee Joon Kang, Hirokazu Takahashi, Kishan K. Chudasama, Jason K. Kim, Anders Molven, C. Ronald Kahn, and Pal R. Njolstad

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The unmet need in rheumatology: reports from the Targeted Therapies meeting 2016, Kevin Winthrop and Jonathan Kay

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Using Best-Worst Scaling to Understand Patient Priorities: A Case Example of Papanicolaou Tests for Homeless Women, Eve Wittenberg, Monica Bharel, John F.P. Bridges, Zachary Ward, and Linda Weinreb

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Defining the Binding Region in Factor H to Develop a Therapeutic Factor H-Fc Fusion Protein against Non-Typeable Haemophilus influenzae, Sandy M. Wong, Jutamas Shaughnessy, Sanjay Ram, and Brian J. Akerley

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Longitudinal changes in neurodevelopmental outcomes between 18 and 36 months in children with prenatal triptan exposure: findings from the Norwegian Mother and Child Cohort Study, Mollie E. Wood, Jean A. Frazier, Hedvig M.E. Nordeng, and Kate L. Lapane

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The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation, Qiong Wu, Pasil A. Madany, Jason Dobson, Jake M. Schnabl, Soni Sharma, Tara C. Smith, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein, Rohini Muthuswami, Anthony N. Imbalzano, and Jeffrey A. Nickerson

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PD-L1 expression in EBV-negative diffuse large B-cell lymphoma: clinicopathologic features and prognostic implications, Wei Xing, Karen A. Dresser, Rui Zhang, Andrew M. Evens, Hongbo Yu, Bruce A. Woda, and Benjamin J. Chen

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RNA polymerase II depletion promotes transcription of alternative mRNA species, Lijian Yu, Mayuri Rege, Craig L. Peterson, and Michael R. Volkert

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The molecular basis of the genesis of basal tone in internal anal sphincter, Cheng-Hai Zhang, Donghai Lui, Ping Lu, Kaizhi Zheng, Siobhan M. Craige, Lawrence Lifshitz, John F. Keaney Jr., Kevin E. Fogarty, Ronghua Zhuge, and Min-Sheng Zhu

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Native and bone marrow-derived cell mosaicism in gastric carcinoma in H. pylori-infected p27-deficient mice, Songhua Zhang, Woojin Kim, Tu T. Pham, Arlin B. Rogers, JeanMarie Houghton, and Steven F. Moss

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miR-124 Regulates the Phase of Drosophila Circadian Locomotor Behavior, Yong Zhang, Pallavi Lamba, Peiyi Guo, and Patrick Emery

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Illuminating Cell Signaling with Near-Infrared Light-Responsive Nanomaterials, Yuanwei Zhang, Ling Huang, Zhan Jun Li, Guolin Ma, Yubin Zhou, and Gang Han