Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2010

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A Key Commitment Step in Erythropoiesis Is Synchronized with the Cell Cycle Clock through Mutual Inhibition between PU.1 and S-Phase Progression, Ramona Pop, Jeffrey R. Shearstone, Qichang Shen, Ying Liu, Kelly N. Hallstrom, Miroslav Koulnis, Joost Gribnau, and Merav Socolovsky

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Prediction of dengue disease severity among pediatric Thai patients using early clinical laboratory indicators, James A. Potts, Robert V. Gibbons, Alan L. Rothman, Anon Srikiatkhachorn, Stephen J. Thomas, Pra-On Supradish, Stephenie C. Lemon, Daniel H. Libraty, Sharone Green, and Siripen Kalayanarooj

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Maturation-dependent licensing of naive T cells for rapid TNF production, Bhavana Priyadharshini, Raymond M. Welsh, Dale L. Greiner, Rachel M. Gerstein, and Michael A. Brehm

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Replication and active demethylation represent partially overlapping mechanisms for erasure of H3K4me3 in budding yeast, Marta Radman-Livaja, Chih Long Liu, Nir Friedman, Stuart L. Schreiber, and Oliver J. Rando

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Modulation of HIV-1 macrophage-tropism among R5 envelopes occurs before detection of neutralizing antibodies, Kathryn H. Richards, Marlen M.I. Aasa-Chapman, Aine McKnight, and Paul R. Clapham

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Multiple uncontrolled conditions and blood pressure medication intensification: an observational study, Amanda H. Salanitro, Ellen M. Funkhouser, Bonita S. Agee, Jeroan J. Allison, Jewell H. Halanych, Thomas K. Houston, Mark S. Litaker, Deborah A. Levine, and Monika M. Safford

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Genome mapping and characterization of the Anopheles gambiae heterochromatin, Maria V. Sharakhova, Phillip George, Irina V. Brusentsova, Scotland C. Leman, Jeffrey A. Bailey, Christopher D. Smith, and Igor V. Sharakhov

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Make Better Choices (MBC): study design of a randomized controlled trial testing optimal technology-supported change in multiple diet and physical activity risk behaviors, Bonnie J. Spring, Kristin L. Schneider, H. G. McFadden, Jocelyn Vaughn, Andrea T. Kozak, Malaina Smith, Arlen C. Moller, Leonard Epstein, Stephanie W. Russell, Andrew DeMott, and Donald Hedeker

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Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species, Anna-Karin E. Svensson, Osman Bilsel, Can Kayatekin, Jessica A. Adefusika, Jill A. Zitzewitz, and C. Robert Matthews

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Toll-like receptor signaling in liver diseases, Gyongyi Szabo, Timothy R. Billiar, Keigo Machida, Ian Nicholas Crispe, and Ekihiro Seki

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Structure-guided Design and Immunological Characterization of Immunogens Presenting the HIV-1 gp120 V3 Loop on a CTB Scaffold, Maxim Totrov, Xunqing Jiang, Xiang-Peng Kong, Sandra cohen, Chavdar Krachmarov, Constance Williams, Michael S. Seaman, Timothy Cardozo, Miroslaw K. Gorny, Shixia Wang, Shan Lu, Abraham Pinter, and Susan Zolla-Pazner

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Profiles of human serum antibody responses elicited by three leading HIV vaccines focusing on the induction of Env-specific antibodies, Michael Vaine, Shixia Wang, Qin Liu, James Arthos, David C. Montefiori, Paul Goepfert, M. Juliana McElrath, and Shan Lu

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Dependence on a retinophilin/myosin complex for stability of PKC and INAD and termination of phototransduction, Kartik Venkatachalam, David Wasserman, Xiaoyue Wang, Ruoxia Li, Eric Mills, Rebecca Elsaesser, Hong-Sheng Li, and Craig Montell

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Enterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation, Didier F. Vingadassalom, Kenneth Geno Campellone, Michael John Brady, Brian M. Skehan, Scott E. Battle, Douglas Robbins, Archana Kapoor, Gail Hecht, Scott B. Snapper, and John M. Leong

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Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis, Stephen N. Waggoner, Ruth T. Taniguchi, Porunelloor A. Mathew, Vinay Kumar, and Raymond M. Welsh

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Rescue of HIV-1 Release by Targeting Widely Divergent NEDD4-Type Ubiquitin Ligases and Isolated Catalytic HECT Domains to Gag, Eric R. Weiss, Elena Popova, Hikaru Yamanaka, Hyung Cheol Kim, Jon M. Huibregtse, and Heinrich G. Göttlinger

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Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics, Jason A. Wilken, Kristy T. Webster, and Nita J. Maihle

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PAMM: a redox regulatory protein that modulates osteoclast differentiation, Yan Xu, Leslie R. Morse, Raquel Assed Bezerra da Silva, Paul R. Odgren, Hajime Sasaki, Philip Stashenko, and Ricardo A. Battaglino

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A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods, Kelvin Yen, Thuc T. Le, Ankita Bansal, Sri Devi Narasimhan, Ji-Xin Cheng, and Heidi A. Tissenbaum

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A complete developmental sequence of a Drosophila neuronal lineage as revealed by twin-spot MARCM, Hung-Hsiang Yu, Chih-Fei Kao, Yisheng He, Peng Ding, Jui-Chun Kao, and Tzumin Lee

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information, Sayyed K. Zaidi, Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein

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Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent, Genhua Zheng, Victor R. Ambros, and Wen-hong Li

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ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data, Lihua Julie Zhu, Claude Gazin, Nathan D. Lawson, Herve Pages, Simon M. Lin, David S. Lapointe, and Michael R. Green

Publications from 2009

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Epigenetic regulation in human brain-focus on histone lysine methylation, Schahram Akbarian and Hsien-Sung Huang

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Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish, Kristen Alexa, Seong-Kyu Choe, Nicolas Hirsch, Letitiah Etheridge, Elizabeth Laver, and Charles G. Sagerstrom

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Identification of flavopiridol analogues that selectively inhibit positive transcription elongation factor (P-TEFb) and block HIV-1 replication, Akbar Ali, Animesh Ghosh, Robin S. Nathans, Natalia Sharova, Siobhan O'Brien, Hong Cao, Mario Stevenson, and Tariq M. Rana

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Tissue damage-induced intestinal stem cell division in Drosophila, Alla Amcheslavsky, Jin Jiang, and Y. Tony Ip

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Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis, Rami I. Aqeilan, John P. Hagan, Alain de Bruin, Maysoon Rawahneh, Zaidoun Salah, Eugenio Gaudio, Hasan Siddiqui, Stefano Volinia, Hansjuerg Alder, Jane B. Lian, Gary S. Stein, and Carlo M. Croce

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Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration, Michelle A. Avery, Amy E. Sheehan, Kimberly S. Kerr, Jing Wang, and Marc R. Freeman

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Autophagy SEPArates germline and somatic cells, Eric H. Baehrecke

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Emerging role of microRNAs in liver diseases, Shashi Bala, Miguel Marcos, and Gyongyi Szabo

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MicroRNAs: regulating a change of heart, Kurt G. Barringhaus and Phillip D. Zamore

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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression, Franz G. Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S. Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G. Monks, Katherine A. Fitzgerald, Veit Hornung, and Eicke Latz

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U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex, Francois Belanger, Huricha Baigude, and Tariq M. Rana

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An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition, Beatrice Benoit, Chun Hua He, Fan Zhang, Sarah M. Votruba, Wael Tadros, J. Timothy Westwood, Craig A. Smibert, Howard D. Lipshitz, and William E. Theurkauf

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CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation, David M. Burns and Joel D. Richter

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Predictors of serum dioxins and PCBs among peripubertal Russian boys, Jane S. Burns, Paige L. Williams, Oleg Sergeyev, Susan Korrick, Mary M. Lee, Boris Revich, Larisa Altshul, Donald G. Patterson, Wayman E. Turner, Larry L. Needham, Igor Saharov, and Russ Hauser

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Cannabinoids, endocannabinoids, and related analogs in inflammation, Sumner H. Burstein and Robert Zurier

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A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells, Eric Campeau, Victoria E. Ruhl, Francis Rodier, Corey Lewis Smith, Brittany L. Rahmberg, Jill O. Fuss, Judith Campisi, Paul Yaswen, Priscilla K. Cooper, and Paul D. Kaufman

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AACAP 2006 Research Forum--Advancing research in early-onset bipolar disorder: barriers and suggestions, Gabrielle A. Carlson, Robert L. Findling, Robert M. Post, Boris Birmaher, Hilary P. Blumberg, Christoph Correll, Melissa P. DelBello, Mary Fristad, Jean A. Frazier, Constance Hammen, Stephen P. Hinshaw, Robert Kowatch, Ellen Leibenluft, Stephanie E. Meyer, Mani N. Pavuluri, Karen Dineen Wagner, and Mauricio Tohen

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Community dimensions and HPSA practice location: 30 years of family medicine training, Suzanne B. Cashman, Judith A. Savageau, Warren J. Ferguson, and Daniel H. Lasser

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Differential roles of insulin-like growth factor receptor- and insulin receptor-mediated signaling in the phenotypes of hepatocellular carcinoma cells, Ya-Wen Chen, Victor L. Boyartchuk, and Brian C. Lewis

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Inhibitory effects of omacetaxine on leukemic stem cells and BCR-ABL-induced chronic myeloid leukemia and acute lymphoblastic leukemia in mice, Y. Chen, Y. Hu, S. Michaels, D. Segal, D. Brown, and S. Li

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Characterization of scatter in cone-beam CT breast imaging: comparison of experimental measurements and Monte Carlo simulation, Yu Chen, Bob Liu, J. Michael O'Connor, Clay S. Didier, and Stephen J. Glick

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Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat, Prerna Chopra, Philip J. Diiorio, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell

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Aurora-A kinase is essential for bipolar spindle formation and early development, Dale O. Cowley, Jaime A. Rivera-Pérez, Mark Schliekelman, Yizhou Joseph He, Trudy G. Oliver, Lucy Lu, Ryan O'Quinn, E. D. Salmon, Terry Magnuson, and Terry Van Dyke

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Conservation of helical bundle structure between the exocyst subunits, Nicole J. Croteau, Melonnie Lynn Marie Furgason, Damien Devos, and Mary Munson

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Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency, Jessica Lynn Crowley, Tara C. Smith, Zhiyou Fang, Norio Takizawa, and Elizabeth J. Luna

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Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation, Caroline S. Dacwag, Mark T. Bedford, Said Sif, and Anthony N. Imbalzano

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Induction of hepatitis by JNK-mediated expression of TNF-alpha, Madhumita Das, Guadalupe Sabio, Feng Jiang, Mercedes Rincon, Richard A. Flavell, and Roger J. Davis

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Disease-causing 7.4 kb cis-regulatory deletion disrupting conserved non-coding sequences and their interaction with the FOXL2 promotor: implications for mutation screening, Barbara D'haene, Catia Attanasio, Diane Beysen, Josee Dostie, Edmond Lemire, Philippe Bouchard, Michael Field, Kristie Jones, Birgit Lorenz, Bjorn Menten, Karen Buysse, Filip Pattyn, Marc Friedli, Catherine Ucla, Colette Rossier, Carine Wyss, Frank Speleman, Anne De Paepe, Job Dekker, Stylianos E. Antonarakis, and Elfride De Baere

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Enforcement of underage sales laws as a predictor of daily smoking among adolescents: a national study, Joseph R. DiFranza, Judith A. Savageau, and Kenneth E. Fletcher

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Ensheathing glia function as phagocytes in the adult Drosophila brain, Johnna E. Doherty, Mary A. Logan, Ozge E. Tasdemir, and Marc R. Freeman

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In vitro and in vivo models of acute alcohol exposure, Angela Dolganiuc and Gyongyi Szabo

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A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses, Raphaëlle Dubruille, Alejandro D. Murad, Michael Rosbash, and Patrick Emery

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Protein kinase D1-mediated phosphorylation and subcellular localization of beta-catenin, Cheng Du, Meena Jaggi, Chuanyou Zhang, and Kethandapatti Balaji

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Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes, Maria J. Duenas-Decamp, Paul J. Peters, Dennis R. Burton, and Paul R. Clapham

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The role of specific checkpoint-induced S-phase transcripts in resistance to replicative stress, Chaitali Dutta and Nicholas R. Rhind

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Casein kinase 1 delta regulates the pace of the mammalian circadian clock, Jean-Pierre Etchegaray, Kazuhiko K. Machida, Elizabeth Noton, Cara M. Constance, Robert Dallmann, Marianne N. Di Napoli, Jason P. DeBruyne, Christopher M. Lambert, Elizabeth A. Yu, Steven M. Reppert, and David R. Weaver

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Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo, Martin Felices, Catherine C. Yin, Yoko Kosaka, Joonsoo Kang, and Leslie J. Berg

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Family medicine residency characteristics associated with practice in a health professions shortage area, Warren J. Ferguson, Suzanne B. Cashman, Judith A. Savageau, and Daniel H. Lasser

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Computerized clinical decision support during medication ordering for long-term care residents with renal insufficiency, Terry S. Field, Paula A. Rochon, Monica Lee, Linda Gavendo, Joann L. Baril, and Jerry H. Gurwitz

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A 30-year perspective (1975-2005) into the changing landscape of patients hospitalized with initial acute myocardial infarction: Worcester Heart Attack Study, Kevin C. Floyd, Jorge L. Yarzebski, Frederick A. Spencer, Darleen M. Lessard, James E. Dalen, Joseph S. Alpert, Joel M. Gore, and Robert J. Goldberg

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Characterization of mouse IFT complex B, John A. Follit, Fenghui Xu, Brian T. Keady, and Gregory J. Pazour

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Neurobiology of pediatric mood disorders: Part II, Jean A. Frazier and Jair C. Soares

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A photo-modulatable material for probing cellular responses to substrate rigidity, Margo Tilley Frey and Yu-Li Wang

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CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance, Randall H. Friedline, David S. Brown, Hai Nguyen, Hardy Kornfeld, Jinhee Lee, Yi Zhang, Mark Appleby, Sandy D. Der, Joonsoo Kang, and Cynthia A. Chambers

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Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris, Yuly F. Fuentes Medel, Mary A. Logan, James A. Ashley, Bulent Ataman, Vivian Budnik, and Marc R. Freeman

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The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p, Melonnie Lynn Marie Furgason, Chris MacDonald, Scott G. Shanks, Sean P. Ryder, Nia J. Bryant, and Mary Munson

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Measuring plasma membrane protein endocytic rates by reversible biotinylation, Luke Gabriel, Zachary H. Stevens, and Haley E. Melikian

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Proper timing of cytokinesis is regulated by Schizosaccharomyces pombe Etd1, Juan Carlos García-Cortés and Dannel McCollum

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Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells, Luiz C. Godoy, Cristina Muñoz-Pinedo, Laura Castro, Simone Cardaci, Christopher M. Schonhoff, Michael King, Verónica Tórtora, Mónica Marín, Qian Miao, Jian Fei Jiang, Alexandr Kapralov, Ronald Jemmerson, Gary G. Silkstone, Jinal N. Patel, James E. Evans, Michael T. Wilson, Douglas R. Green, Valerian E. Kagan, Rafael Radi, and Joan B. Mannick

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Integrin signaling aberrations in prostate cancer, Hira Lal Goel, Naved Alam, Isaac N.S. Johnson, and Lucia R. Languino

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Thirty-year trends (1975 to 2005) in the magnitude of, management of, and hospital death rates associated with cardiogenic shock in patients with acute myocardial infarction: a population-based perspective, Robert J. Goldberg, Frederick A. Spencer, Joel M. Gore, Darleen M. Lessard, and Jorge L. Yarzebski

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Trends in health sciences library and information science research: an analysis of research publications in the Bulletin of the Medical Library Association and Journal of the Medical Library Association from 1991 to 2007, Sally A. Gore, Judy M. Nordberg, Lisa A. Palmer, and Mary E. Piorun

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Clinical images: beyond the classic triad: dermatologic manifestations of reactive arthritis, Sheila M. Greenlaw, Lauren Alberta-Wszolek, and Amit Garg

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Occam's dull razor: MDM2 and P/CAF keep Chk2 in check the hard way, Steven R. Grossman

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Generation of protective T cell-independent antiviral antibody responses in SCID mice reconstituted with follicular or marginal zone B cells, Heath M. Guay, Rabinarayan Mishra, Robert L. Garcea, Raymond M. Welsh, and Eva Szomolanyi-Tsuda

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Medial patellofemoral ligament injury patterns and associated pathology in lateral patella dislocation: an MRI study, Patrick Guerrero, Xinning Li, Ketan Patel, Michael Brown, and Brian D. Busconi

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Survivin as a global target of intrinsic tumor suppression networks, Minakshi Guha and Dario C. Altieri

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The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice, Michelle L. Gumz, Lisa R. Stow, I. Jeanette Lynch, Megan M. Greenlee, Alicia Rudin, Brian D. Cain, David R. Weaver, and Charles D. Wingo

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Can anticoagulation care be improved with technology, Jerry H. Gurwitz

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AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome, Lisa L. Hall, Meg Byron, Gayle Jeannette Pageau, and Jeanne B. Lawrence

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nhl-2 Modulates microRNA activity in Caenorhabditis elegans, Christopher M. Hammell, Isabella Lubin, Peter R. Boag, T. Keith Blackwell, and Victor R. Ambros

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Transmembrane passage of hydrophobic compounds through a protein channel wall, Elizabeth M. Hearn, Dimki R. Patel, Bryan W. Lepore, Mridhu Indic, and Bert Van den Berg

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Abrogation of the postmitotic checkpoint contributes to polyploidization in human papillomavirus E7-expressing cells, Susan Ann Heilman, Joshua J. Nordberg, Yingwang Liu, Greenfield Sluder, and Jason J. Chen

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Pancreatic neuroendocrine tumors: the impact of surgical resection on survival, Joshua S. Hill, James T. McPhee, Theodore P. McDade, Zheng Zhou, Mary E. Sullivan, Giles F. Whalen, and Jennifer F. Tseng

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The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design, Frederick H. Hooven, Jonathan D. Adachi, Silvano Adami, Steven Boonen, Juliet E. Compston, Cyrus Cooper, Pierre Delmas, Adolfo Diez-Perez, Stephen H. Gehlbach, Susan L. Greenspan, Andrea Z. LaCroix, Robert Lindsay, J. Coen Netelenbos, Johannes Pfeilschifter, Christian Roux, Kenneth G. Saag, Phillip Sambrook, Stuart Silverman, Ethel S. Siris, Nelson B. Watts, and Frederick A. Anderson Jr.

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC, Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz G. Bauernfeind, Gabor Horvath, Daniel R. Caffrey, Eicke Latz, and Katherine A. Fitzgerald

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Resting heart rate as a low tech predictor of coronary events in women: prospective cohort study, Judith Hsia, Joseph C. Larson, Judith K. Ockene, Gloria E. Sarto, Matthew A. Allison, Susan L. Hendrix, Jennifer G. Robinson, Andrea Z. LaCroix, and JoAnn E. Manson

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Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists, Haibin Huang, Gary R. Ostroff, Chrono K. Lee, Jennifer P. Wang, Charles A. Specht, and Stuart M. Levitz

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Chromatin 'programming' by sequence - is there more to the nucleosome code than %GC, Amanda Hughes and Oliver J. Rando

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Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture, Karen M. Imbalzano, Iva Tatarkova, Anthony N. Imbalzano, and Jeffrey A. Nickerson

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Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice, Smita Jaiswal, Todd Pearson, Heather Friberg, Leonard D. Shultz, Dale L. Greiner, Alan L. Rothman, and Anuja Mathew

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Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94, Chihiro Kakiuchi, Shinsuke Ishigaki, Christine M. Oslowski, Sonya G. Fonseca, Tadafumi Kato, and Fumihiko Urano

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Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90, Byoung Heon Kang, Janet Plescia, Ho Young Song, Massimiliano Meli, Giorgio Colombo, Kristin Beebe, Bradley Scroggins, Len Neckers, and Dario C. Altieri

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The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters, Carla Andrea Klattenhoff, Hualin Xi, Chengjian Li, Soohyun Lee, Jia Xu, Jaspreet S. Khurana, Fan Zhang, Nadine Schultz, Birgit S. Koppetsch, Anetta Nowosielska, Herve Seitz, Phillip D. Zamore, Zhiping Weng, and William E. Theurkauf

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Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart, Hwi Jin Ko, Zhiyou Zhang, Dae Young Jung, John Y. Jun, Zhexi Ma, Kelly E. Jones, Sook Y. Chan, and Jason K. Kim

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Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning, Adrianne L. Kolpak, Jun Jiang, Daorong Guo, Clive Standley, Karl D. Bellve, Kevin E. Fogarty, and Zheng-Zheng Bao

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The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella, Karl-Ferdinand Lechtreck, Eric C. Johnson, Tsuyoshi Sakai, Deborah A. Cochran, Bryan A. Ballif, John Rush, Gregory J. Pazour, Mitsuo Ikebe, and George B. Witman