Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2015

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Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections, Shen-Ying Zhang, Anne Marie Comeau, Jean-Laurent Casanova, Kaan Boztug, and Luigi D. Notarangelo

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Cluster-based Epidemic Control Through Smartphone-based Body Area Networks, Zhaoyang Zhang, Honggang Wang, Chonggang Wang, and Hua (Julia) Fang

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A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation, Huaying Zhao, Kimberly A. Crowley, Craig L. Peterson, Sarah G. Swygert, and Peter Schuck

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Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes, Jiali Zhuang and Zhiping Weng

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Progression of Large Lymphoma Is Significantly Impeded with a Combination of Gemcitabine Chemotherapy and Dendritic Cells Intra-Tumor Vaccination, Xue-Jun Zhu, Zhongfa Yang, Jin-Yong Zhou, Li Liu, Xue-Mei Sun, Zhen-Fang Fan, Shou-You Hu, Yu-Chao Chen, Wei-Xia Li, Meng Cao, and Li-Xin Wang

Publications from 2014

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Induction of IL-12 production in human peripheral monocytes by Trypanosoma cruzi Is mediated by glycosylphosphatidylinositol-anchored mucin-like glycoproteins and potentiated by IFN- gamma and CD40-CD40L interactions, Lucia Cristina Abel Jamli, Ludmila Rodrigues Ferreira Pinto, Isabela Cunha Navarro, Monique Andrade Baron, Jorge Kalil, Ricardo T. Gazzinelli, Luiz Vicente Rizzo, and Edecio Cunha-Neto

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Post-Autologous (ASCT) Stem Cell Transplant Therapy in Multiple Myeloma, Zeina Al-Mansour and Muthalagu Ramanathan

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The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria, Lis R.V. Antonelli, Fabiana M.S. Leoratti, Pedro A.C. Costa, Bruno C. Rocha, Suelen Q. Diniz, Mauro S. Tada, Dhelio B. Pereira, Andrea Teixeira-Carvalho, Douglas T. Golenbock, Ricardo Goncalves, and Ricardo T. Gazzinelli

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The home environment and childhood obesity in low-income households: indirect effects via sleep duration and screen time, Bradley M. Appelhans, Stephanie L. Fitzpatrick, Hong Li, Vernon Cail, Molly E. Waring, Kristin L. Schneider, Matthew C. Whited, Andrew M. Busch, and Sherry L. Pagoto

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Genetic vaccination against experimental infection with myotropic parasite strains of Trypanosoma cruzi, Adriano Fernando Araujo, Gabriel de Oliveira, Juliana Fraga Vasconcelos, Jonatan Ersching, Mariana Ribeiro Dominguez, Jose Ronnie Vasconcelos, Alexandre Vieira Machado, Ricardo T. Gazzinelli, Oscar Bruna-Romero, Milena Botelho Soares, and Mauricio Martins Rodrigues

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Human breast progenitor cell numbers are regulated by WNT and TBX3, Lisa M. Arendt, Jessica St. Laurent, Ania Wronski, Silvia Caballero, Stephen Lyle, Stephen P. Naber, and Charlotte Kuperwasser

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Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection, Marco A. Ataide, Warrison A. Andrade, Dario S. Zamboni, Donghai Wang, Maria do Carmo Souza, Bernardo S. Franklin, Samir Elian, Flaviano S. Martins, Dhelio Pereira, George W. Reed, Katherine A. Fitzgerald, Douglas T. Golenbock, and Ricardo T. Gazzinelli

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NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone, Junya Awata, Saeko Takada, Clive Standley, Karl-Ferdinand Lechtreck, Karl D. Bellve, Gregory J. Pazour, Kevin E. Fogarty, and George B. Witman

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Joint replacement registries in the United States: a new paradigm, David C. Ayers and Patricia D. Franklin

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High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody, Gregory J. Babcock, Sowmya Iyer, Heidi L. Smith, Yan Wang, Kirk Rowley, Donna M. Ambrosino, Phillip D. Zamore, Brian G. Pierce, Deborah C. Molrine, and Zhiping Weng

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Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals, Shashi Bala, Miguel Marcos, Arijeet Gattu, Donna Catalano, and Gyongyi Szabo

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Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan, Ankita Bansal, Eun-Soo Kwon, Darryl Conte Jr., Haibo Liu, Michael J. Gilchrist, Lesley T. MacNeil, and Heidi A. Tissenbaum

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Protective immunity and safety of a genetically modified influenza virus vaccine, Rafael Polidoro Alves Barbosa, Ana Paula Carneiro Salgado, Cristiana Couto Garcia, Bruno Galvao Filho, Ana Paula de Faria Paula de Faria Goncalves, Braulio Henrique Freire Lima, Gabriel Augusto Oliveira Lopes, Milene Alvarenga Rachid, Andiara Cristina Cardoso Peixoto, Danilo Bretas de Oliveira, Marco Antonio Ataide, Carla Aparecida Zirke, Tatiane Marques Cotrim, Erica Azevedo Costa, Gabriel Magno de Freitas Almeida, Remo Castro Russo, Ricardo T. Gazzinelli, and Alexandre de Magalhaes Vieira Machado

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The relationship between subnormal peak-stimulated growth hormone levels and auxological characteristics in obese children, Jefferson Barrett, Louise S. Maranda, and Benjamin U. Nwosu

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Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA, Hanni Bartels and Jeremy Luban

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The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter, Rasim Barutcu, Phillip W. Tai, Hai Wu, Jonathan A. R. Gordon, Troy W. Whitfield, Jason Dobson, Anthony N. Imbalzano, Jane B. Lian, Andre J. van Wijnen, Janet L. Stein, and Gary S. Stein

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A conserved dopamine-cholecystokinin signaling pathway shapes context-dependent Caenorhabditis elegans behavior, Raja Bhattacharya, Denis Touroutine, Belinda Barbagallo, Jason Climer, Christopher M. Lambert, Christopher M. Clark, Mark J. Alkema, and Michael M. Francis

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The spatial dynamics of dengue virus in Kamphaeng Phet, Thailand, Piraya Bhoomiboonchoo, Robert V. Gibbons, Angkana Huang, In-Kyu Yoon, Darunee Buddhari, Ananda Nisalak, Natkamol Chansatiporn, Mathuros Thipayamongkolgul, Siripen Kalanarooj, Timothy Endy, Alan L. Rothman, Anon Srikiatkhachorn, Sharone Green, Mammen P. Mammen, Derek A. Cummings, and Henrik Salje

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A survey study of evidence-based medicine training in US and Canadian medical schools, Maria A. Blanco, Carol F. Capello, Josephine L. Dorsch, Gerald (Jerry) Perry, and Mary L. Zanetti

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A randomized controlled trial of mental health interventions for survivors of systematic violence in Kurdistan, Northern Iraq, Paul Bolton, Judith K. Bass, Goran Zangana, Talar Kamal, Sarah Murray, Debra Kaysen, Carl W. Lejuez, Kristen Lindgren, Sherry L. Pagoto, Laura K. Murray, Stephanie Van Wyk, Ahmed Ahmed, Nazar M. Mohammad Amin, and Michael Rosenblum

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Dengue virus neutralizing antibody levels associated with protection from infection in Thai cluster studies, Darunee Buddhari, Jared Aldstadt, Timothy P. Endy, Anon Srikiatkhachorn, Butsaya Thaisomboonsuk, Chonticha Klungthong, Ananda Nisalak, Benjawan Khuntirat, Richard G. Jarman, Stefan Fernandez, Stephen J. Thomas, Thomas W. Scott, Alan L. Rothman, and In-Kyu Yoon

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Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90, Terence N. Bukong, Fatemeh Momen-Heravi, Karen Kodys, Shashi Bala, and Gyongyi Szabo

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A deterministic model predicts the properties of stochastic calcium oscillations in airway smooth muscle cells, Pengxing Cao, Xiahui Tan, Graham Donovan, Michael J. Sanderson, and James Sneyd

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Antiplatelet activity, P2Y(1) and P2Y(1)(2) inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'''-P(1) ,P(4)-dithio-P(2),P(3)-chloromethylenetetraphosphate, Hung Chang, Ivan B. Yanachkov, Edward J. Dix, Milka Yanachkova, Youfu Li, Marc R. Barnard, George E. Wright, Alan D. Michelson, and Andrew L. Frelinger III

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Estudio Parto: postpartum diabetes prevention program for hispanic women with abnormal glucose tolerance in pregnancy: a randomised controlled trial - study protocol, Lisa Chasan-Taber, Bess H. Marcus, Milagros C. Rosal, Katherine L. Tucker, Sheri J. Hartman, Penelope S. Pekow, Barry Braun, Tiffany A. Moore Simas, Caren G. Solomon, Joann E. Manson, and Glenn Markenson

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Unbiased chromatin accessibility profiling by RED-seq uncovers unique features of nucleosome variants in vivo, Poshen B. Chen, Lihua Julie Zhu, Sarah J. Hainer, Kurtis N. McCannell, and Thomas G. Fazzio

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Arachidonate 15-lipoxygenase is required for chronic myeloid leukemia stem cell survival, Yaoyu Chen, Cong Peng, Sheela A. Abraham, Yi Shan, Zhiru Guo, Ngoc Desouza, Giulia Cheloni, Dongguang Li, Tessa L. Holyoake, and Shaoguang Li

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Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport, Kyoko Chiba, Masahiko Araseki, Keisuke Nozawa, Keiko Furukori, Yoichi Araki, Takahide Matsushima, Tadashi Nakaya, Saori Hata, Yuhki Saito, Seiichi Uchida, Yasushi Okada, Angus C. Nairn, Roger J. Davis, Tohru Yamamoto, Masataka Kinjo, Hidenori Taru, and Toshiharu Suzuki

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Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite, Carina C. Clingman, Laura M. Deveau, Samantha A. Hay, Ryan M. J. Genga, Shivender Shandilya, Francesca Massi, and Sean P. Ryder

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Psychopathic traits modulate brain responses to drug cues in incarcerated offenders, Lora M. Cope, Gina M. Vincent, Justin L. Jobelius, Prashanth K. Nyalakanti, Vince D. Calhoun, and Kent A. Kiehl

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Blank-comparison matching-to-sample reveals a false positive symmetry test in a capuchin monkey, Ana Leda de Faria Brino, Rodolfo da Silva Campos, Olavo de Faria Galvao, and William J. McIlvane

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Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA, Alberto De Iaco and Jeremy Luban

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Two ways to fold the genome during the cell cycle: insights obtained with chromosome conformation capture, Job Dekker

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Quitters referring smokers: a quitline chain-referral pilot study, Kathryn L. Delaughter, Julie E. Volkman, Barrett D. Phillips, and Thomas K. Houston

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Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast, Noah Dephoure, Sunyoung Hwang, Ciara O'Sullivan, Stacie E. Dodgson, Steven P. Gygi, Angelika Amon, and Eduardo M. Torres

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IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion, Tanay M. Desai, Mariana Marin, Christopher R. Chin, George Savidis, Abraham L. Brass, and Gregory B. Melikyan

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hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3, Jason R. Dobson, Hanna Taipaleenmaki, Yu-Jie Hu, Deli Hong, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Jane B. Lian, and Jitesh Pratap

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PI3K signaling and Stat92E converge to modulate glial responsiveness to axonal injury, Johnna E. Doherty, Amy E. Sheehan, Rachel Bradshaw, A. Nicole Fox, Tsai-yi Lu, and Marc R. Freeman

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Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice, Shuping Dou, John Virostko, Mary Rusckowski, Dale L. Greiner, Alvin C. Powers, and Guozheng Liu

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TLR4 activation induces IL-1ss release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung, Suffwan Eltom, Maria G. Belvisi, Liang Yew-Booth, Bilel Dekkak, Sarah A. Maher, Eric D. Dubuis, Victoria Jones, Kate A. Fitzgerald, and Mark A. Birrell

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Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors, Itzel Escobedo-Avila, Fernanda Vargas-Romero, Anayansi Molina-Hernandez, Rodrigo Lopez-Gonzalez, Daniel Cortes, Juan A. De Carlos, and Ivan Velasco

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Genetic models of apoptosis-induced proliferation decipher activation of JNK and identify a requirement of EGFR signaling for tissue regenerative responses in Drosophila, Yun Fan, Shiuan Wang, Jacob Hernandez, Vildan Betul Yenigun, Gillian Hertlein, Caitlin E. Fogarty, Jillian L. Lindblad, and Andreas Bergmann

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Approaches for classifying the indications for colonoscopy using detailed clinical data, Hirut Fassil, Kenneth F. Adams, Sheila Weinmann, V. Paul Doria-Rose, Eric Johnson, Andrew E. Williams, Douglas A. Corley, and Chyke A. Doubeni

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Evaluation of naturally acquired IgG antibodies to a chimeric and non-chimeric recombinant species of Plasmodium vivax reticulocyte binding protein-1: lack of association with HLA-DRB1*/DQB1* in malaria exposed individuals from the Brazilian Amazon, Amanda Ribeiro Ferreira, Balwan Singh, Monica Cabrera-Mora, Alana Cristina Magri De Souza, Maria Teresa Queiroz Marques, Luis Cristovao Sobrino Porto, Fatima Santos, Dalma Maria Banic, J. Mauricio Calvo-Calle, Joseli Oliveira-Ferreira, Alberto Moreno, and Josue Da Costa Lima-Junior

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Arf4 is required for Mammalian development but dispensable for ciliary assembly, John A. Follit, Jovenal T. San Agustin, Julie A. Jonassen, Tingting Huang, Jaime A. Rivera-Perez, Kimberly D. Tremblay, and Gregory J. Pazour

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Influenza virus drug resistance: a time-sampled population genetics perspective, Matthieu Foll, Yu Ping Poh, Nicholas Renzette, Anna Ferrer Admetlla, Claudia Bank, Hyunjin Shim, Anna Sapfo Malaspinas, Gregory Ewing, Ping Liu, Daniel Wegmann, Daniel R. Caffrey, Konstantin B. Zeldovich, Daniel N. A. Bolon, Jennifer Wang, Timothy F. Kowalik, Celia A. Schiffer, Robert W. Finberg, and Jeffrey D. Jensen

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Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score, Keith A. A. Fox, Gordon FitzGerald, Etienne Puymirat, Wei Huang, Kathryn Carruthers, Tabassome Simon, Pierre Coste, Jacques Monsegu, Phillippe Gabriel Steg, Nicolas Danchin, and Frederick A. Anderson Jr.

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Upper extremity injury management by non-physician emergency practitioners in rural Uganda: A pilot study, Daniel S. Frank, Katie Dunleavy, Rashidah Nambaziira, Irene Nayebare, Bradley Dreifuss, and Mark Bisanzo

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Implementation of patient-reported outcome measures in U.S. Total joint replacement registries: rationale, status, and plans, Patricia D. Franklin, David Lewallen, Kevin Bozic, Brian Hallstrom, William Jiranek, and David C. Ayers

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Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters, Juan I. Fuxman Bass, Alex M. Tamburino, Akihiro Mori, Nathan Beittel, Matthew T. Weirauch, John S. Reece-Hoyes, and Albertha J. M. Walhout

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A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection, Don B. Gammon, Sophie Duraffour, Daniel K. Rozelle, Heidi Hehnly, Rita Sharma, Michael E. Sparks, Cara C. West, Ying Chen, James J. Moresco, Graciela Andrei, John H. Connor, Darryl Conte Jr., Dawn E. Gundersen-Rindal, William L. Marshall, John R. Yates, Neal S. Silverman, and Craig C. Mello

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Fidelity of Histone Gene Regulation is Obligatory for Genome Replication and Stability, Prachi N. Ghule, Ronglin Xie, Ricardo F. Medina, Jennifer L. Colby, Stephen N. Jones, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein

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An improved predictive recognition model for Cys(2)-His(2) zinc finger proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J. Keith Joung, Scot A. Wolfe, and Gary D. Stormo

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An improved predictive recognition model for Cys2-His2 zinc finger proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J. Keith Joung, Scot A. Wolfe, and Gary D. Stormo

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The rheumatoid arthritis treat-to-target trial: a cluster randomized trial within the Corrona rheumatology network, Leslie R. Harrold, George W. Reed, J. Timothy Harrington, Christine J. Barr, Katherine C. Saunders, Allan Gibofsky, Jeffrey D. Greenberg, Ani John, Jenny Devenport, and Joel M. Kremer

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The comparative effectiveness of abatacept versus anti-tumour necrosis factor switching for rheumatoid arthritis patients previously treated with an anti-tumour necrosis factor, Leslie R. Harrold, George W. Reed, Joel M. Kremer, Jeffrey R. Curtis, Daniel H. Solomon, Marc C. Hochberg, and Jeffrey D. Greenberg

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Teaching tobacco dependence treatment and counseling skills during medical school: rationale and design of the Medical Students helping patients Quit tobacco (MSQuit) group randomized controlled trial, Rashelle B. Hayes, Alan C. Geller, Linda C. Churchill, Denise G. Jolicoeur, David M. Murray, Abigail Shobend, Sean P. David, Michael Adams, Kola Okuyemi, Randy Fauver, Robin Gross, Frank Leone, Rui Xiao, Jonathan Waugh, Sybil L. Crawford, and Judith K. Ockene

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Myogenic Enhancers Regulate Expression of the Facioscapulohumeral Muscular Dystrophy-Associated DUX4 Gene, Charis L. Himeda, Celine Debarnot, Sachiko Homma, Mary Lou Beermann, Jeffrey B. Miller, Peter L. Jones, and Takako I. Jones

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MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis, Andrew G. Hoss, Vinay K. Kartha, Xianjun Dong, Jeanne C. Latourelle, Alexandra Dumitriu, Tiffany C. Hadzi, Marcy E. Macdonald, James F. Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, and Richard H. Myers

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Profiles of acute cytokine and antibody responses in patients infected with avian influenza A H7N9, Rui Huang, Lu Zhang, Qin Gu, Yi-Hua Zhou, Yingying Hao, Kui Zhang, Yong Liu, Danjiang Dong, Shixia Wang, Zuhu Huang, Shan Lu, and Chao Wu

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The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins, Andree Hubber, Kohei Arasaki, Fubito Nakatsu, Camille Hardiman, David G. Lambright, Pietro De Camilli, Hiroki Nagai, and Craig R. Roy

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Rictor/mTORC2 Loss in the Myf5 Lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease, Chien-Min Hung, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Huawei Li, Clary B. Clish, Simone Hettmer, Amy J. Wagers, and David A. Guertin

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Association between Smoking and Health Outcomes in Postmenopausal Women Living with Multiple Sclerosis, Rachel Jawahar, Unsong Oh, Charles Eaton, Nicole Wright, Hilary Tindle, and Kate L. Lapane

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Emergency department patient safety incident characterization: an observational analysis of the findings of a standardized peer review process, Zach K. Jepson, Chad E. Darling, Kevin A. Kotkowski, Steven B. Bird, Michael W. Arce, Gregory A. Volturo, and Martin A. Reznek

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A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling beta-glucan microparticles, Magdia De Jesus, Gary R. Ostroff, Stuart M. Levitz, Toni R. Bartling, and Nicholas J. Mantis

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Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses, Hiroshi Kataoka, Hajime Kono, Zubin Patel, and Kenneth L. Rock

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Clinical disease activity and acute phase reactant levels are discordant among patients with active rheumatoid arthritis: acute phase reactant levels contribute separately to predicting outcome at one year, Jonathan Kay, Olga Morgacheva, Susan P. Messing, Joel M. Kremer, Jeffrey D. Greenberg, George W. Reed, Ellen M. Gravallese, and Daniel E. Furst

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Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells, Nicola A. Kearns, Ryan M. J. Genga, Metewo Selase Enuameh, Manuel Garber, Scot A. Wolfe, and Rene Maehr

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Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction, Kimberly S. Kerr, Yuly F. Fuentes Medel, Cassandra Brewer, Romina Barria, James A. Ashley, Katharine C. Abruzzi, Amy E. Sheehan, Ozge E. Tasdemir, Marc R. Freeman, and Vivian Budnik

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The islet estrogen receptor-alpha is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes, Gamze Kilic, Ana I. Alvarez-Mercado, Bader Zarrouki, Darren Opland, Chong Wee Liew, Laura C. Alonso, Martin G. Myers Jr, Jean-Christophe Jonas, Vincent Poitout, Rohit N. Kulkarni, and Franck Mauvais-Jarvis

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Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes, Nora M. Kochupurakkal, Annie J. Kruger, Sudipta Tripathi, Bing Zhu, La Tonya Adams, Daniel B. Rainbow, Aldo A. Rossini, Dale L. Greiner, Mohamed H. Sayegh, Linda S. Wicker, and Indira Guleria

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Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet, Carolyn D. Kramer, Ellen O. Weinberg, Adam C. Gower, Xianbao He, Samrawit Mekasha, Connie Slocum, Lea M. Beaulieu, Lee Wetzler, Yuriy Alekseyev, Frank C. Gibson III, Jane E. Freedman, Robin R. Ingalls, and Caroline A. Genco

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Optimization of transcription factor binding map accuracy utilizing knockout-mouse models, Wolfgang Krebs, Susanne V. Schmidt, Alon Goren, Dominic De Nardo, Larisa Labzin, Anton Bovier, Thomas Ulas, Heidi Theis, Michael Kraut, Eicke Latz, Marc Beyer, and Joachim L. Schultze

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A conserved flagella-associated protein in Chlamydomonas, FAP234, is essential for axonemal localization of tubulin polyglutamylase TTLL9, Tomohiro Kubo, Haru-aki Yanagisawa, Zhongmei Liu, Rie Shibuya, Masafumi Hirono, and Ritsu Kamiya

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Coincident pre-diabetes is associated with dysregulated cytokine responses in pulmonary tuberculosis, Nathella Pavan Kumar, Vaithilingam V. Banurekha, Dina Nair, Rathinam Sridhar, Hardy Kornfeld, Thomas B. Nutman, and Subash Babu

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Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors, Govind Kunduri, Changqing Yuan, Velayoudame Parthibane, Katherine M. Nyswaner, Ritu Kanwar, Kunio Nagashima, Steven G. Britt, Nickita Mehta, Varshika Kotu, Mindy Porterfield, Michael Tiemeyer, Patrick J. Dolph, Usha Acharya, and Jairaj K. Acharya

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Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production, Patricia Langjahr, David Diaz-Jimenez, Marjorie De la Fuente, Estefhany Rubio, Douglas T. Golenbock, Francisca C. Bronfman, Rodrigo Quera, Maria-Julieta Gonzalez, and Marcela A. Hermoso

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The PPARgamma locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner, Scott E. LeBlanc, Qiong Wu, A. Rasim Barutcu, Hengyi Xiao, Yasuyuki Ohkawa, and Anthony N. Imbalzano

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Weight gain prevention in the school worksite setting: Results of a multi-level cluster randomized trial, Stephenie C. Lemon, Monica L. Wang, Nicole M. Wedick, Barbara Estabrook, Susan Druker, Kristin L. Schneider, Wenjun Li, and Lori Pbert

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Circulating levels of soluble MICB in infants with symptomatic primary dengue virus infections, Daniel H. Libraty, Lei Zhang, AnaMae Obcena, Job D. Brion, and Rosario Z. Capeding

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Low adiposity during early infancy is associated with a low risk for developing dengue hemorrhagic fever: a preliminary model, Daniel H. Libraty, Lei Zhang, Marcia Woda, Krisanthi Giaya, Chido Loveness Kathivu, Luz P. Acosta, Veronica Tallo, Edelwisa Segubre-Mercado, Analisa Bautista, AnaMae Obcena, Job D. Brion, and Rosario Z. Capeding

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Frailty index of deficit accumulation and falls: data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) Hamilton cohort, Guowei Li, George Ioannidis, Laura Pickard, Courtney Kennedy, Alexandra Papaioannou, Lehana Thabane, and Jonathan D. Adachi

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Concurrent measurement of dynamic changes in viral load, serum enzymes, T cell subsets, and cytokines in patients with severe fever with thrombocytopenia syndrome, Jun Li, Yaping Han, Yiping Xing, Shuang Li, Lianhua Kong, Yongxiang Zhang, Lili Zhang, Ning Liu, Qian Wang, Shixia Wang, Shan Lu, and Zuhu Huang

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Whole blood gene expression and atrial fibrillation: the Framingham Heart Study, Honghuang Lin, Xiaoyan Yin, Kathryn L. Lunetta, Josee Dupuis, David D. McManus, Steven A. Lubitz, Jared W. Magnani, Roby Joehanes, Peter J. Munson, Martin G. Larson, Daniel Levy, Patrick T. Ellinor, and Emelia J. Benjamin

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Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from symptomatic men attending the Nanjing sexually transmitted diseases clinic (2011-2012): genetic characteristics of isolates with reduced sensitivity to ceftriaxone, Sai Li, Xiao-Hong Su, Wen-Jing Le, Fa-Xing Jiang, Bao-Xi Wang, and Peter A. Rice

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Learning to rank figures within a biomedical article, Feifan Liu and Hong Yu

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Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6, Wan-Ju Liu, John S. Reece-Hoyes, Albertha J. M. Walhout, and David M. Eisenmann

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Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice, Stephen Lyle, Kathleen Hoover, Cansu Colpan, Zhiqing Zhu, Zdenka Matijasevic, and Stephen N. Jones

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Aripiprazole Decreases Irritability in 12 out of 14 Youth with Autism Spectrum Disorders, Ann E. Maloney, Eric O. Mick, and Jean A. Frazier

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Angiomotins link F-actin architecture to Hippo pathway signaling, Sebastian Mana-Capelli, Murugan Paramasivam, Shubham Dutta, and Dannel McCollum

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Pregnancy-associated breast cancers are driven by differences in adipose stromal cells present during lactation, Jessica McCready, Lisa M. Arendt, Eugene Glover, Vandana Iyer, Jerrica L. Briendel, Stephen Lyle, Stephen P. Naber, Daniel G. Jay, and Charlotte Kuperwasser

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Genome-wide association study of proneness to anger, Eric O. Mick, James J. McGough, Curtis K. Deutsch, Jean A. Frazier, David N. Kennedy, and Robert J. Goldberg

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Patterns of initiation of second generation antipsychotics for bipolar disorder: a month-by-month analysis of provider behavior, Christopher J. Miller, Mingfei Li, Robert B. Penfold, Austin F. Lee, Eric G. Smith, David N. Osser, Laura Bajor, and Mark S. Bauer

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The hunt for protective correlates of immunity to Plasmodium falciparum malaria, Ann M. Moormann and V. Ann Stewart

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Sickle cell trait is not associated with endemic Burkitt lymphoma: an ethnicity and malaria endemicity-matched case-control study suggests factors controlling EBV may serve as a predictive biomarker for this pediatric cancer, David H. Mulama, Jeffrey A. Bailey, Joslyn Foley, Kiprotich Chelimo, Collins Ouma, Walter G.Z.O. Jura, Juliana A. Otieno, John M. Vulule, and Ann M. Moormann