Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2016

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Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species, Jiang He, Ruobo Zhou, Zhuhao Wu, Monica A. Carrasco, Peri T. Kurshan, Jonathan E. Farley, David J. Simon, Guiping Wang, Boran Han, Junjie Hao, Evan Heller, Marc R. Freeman, Kang Shen, Tom Maniatis, Marc Tessier-Lavigne, and Xiaowei Zhuang

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Forward genetic screen of human transposase genomic rearrangements, Anton G. Henssen, Eileen Jiang, Jiali Zhuang, Luca Pinello, Nicholas D. Socci, Richard Koche, Mithat Gonen, Camila M. Villasante, Scott A. Armstrong, Daniel E. Bauer, Zhiping Weng, and Alex Kentsis

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Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria, Isabella C. Hirako, Marco Antonio Ataide, Lucas Faustino, Patricia A. Assis, Elizabeth W. Sorensen, Hisashi Ueta, Natalia M. Araujo, Gustavo B. Menezes, Andrew D. Luster, and Ricardo T. Gazzinelli

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Data Citation in Neuroimaging: Proposed Best Practices for Data Identification and Attribution, Leah B. Honor, Christian Haselgrove, Jean A. Frazier, and David N. Kennedy

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Single molecule analysis reveals reversible and irreversible steps during spliceosome activation, Aaron A. Hoskins, Margaret L. Rodgers, Larry J. Friedman, Jeff Gelles, and Melissa J. Moore

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Hypercalcemia due to Primary Hepatic Lymphoma, Andrew Hsu, Michael Gagnier, Elizabeth Ryer, Mohammed Salhab, and Alan G. Rosmarin

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Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes, Henry Huang, Eric S. Veien, Hong Zhang, David C. Ayers, and Jie Song

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Monitoring cell-cell contacts in vivo in transgenic animals, Ting-Hao Huang, Tarciso Velho, and Carlos Lois

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Epstein-Barr Virus Infection of Mammary Epithelial Cells Promotes Malignant Transformation, Hai Hu, Joyce D. Fingeroth, and Gerburg M. Wulf

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A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI network, Elena V. Ignatieva, Dmitry A. Afonnikov, Olga V. Saik, Evgeny I. Rogaev, and Nikolay A. Kolchanov

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Small Molecule Inhibitor of CBFbeta-RUNX Binding for RUNX Transcription Factor Driven Cancers, Anuradha Illendula, John A. Pulikkan, Lucio H. Castilla, and John H. Bushweller

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An Intact Dissecting Baker's Cyst Mimicking Recurrent Deep Vein Thrombosis, Sarah Jamshed and L. Michael Snyder

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Improved B cell development in humanized NOD-scid IL2Rgammanull mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3, Sonal Jangalwe, Leonard D. Shultz, Anuja Mathew, and Michael A. Brehm

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GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis, Guillaume Jannot, Pascale Michaud, Miguel Quevillon Huberdeau, Louis Morel-Berryman, James A. Brackbill, Sandra Piquet, Katherine McJunkin, Kotaro Nakanishi, and Martin J. Simard

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Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice, Adam Jara, Xingbo Liu, Don Sim, Chance M. Benner, Silvana Duran-Ortiz, Yanrong Qian, Edward O. List, Darlene E. Berryman, Jason K. Kim, and John J. Kopchick

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TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection, Pushpalatha Jayaraman, Miye K. Jacques, Chen Zhu, Katherine Steblenko, Britni L. Stowell, Asaf Madi, Ana C. Anderson, Vijay K. Kuchroo, and Samuel M. Behar

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Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo, Hyein Jeon, Jae Hwan Kim, Eunjung Lee, Young Jin Jang, Joe Eun Son, Jung Yeon Kwon, Tae-Gyu Lim, Sunghoon Kim, Jung Han Yoon Park, Jong-Eun Kim, and Ki Won Lee

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Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD), Takako I. Jones, Megan Parilla, and Peter L. Jones

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Results of a Culturally Adapted Internet-Enhanced Physical Activity Pilot Intervention for Overweight and Obese Young Adult African American Women, Rodney P. Joseph, Dori Pekmezi, Gareth R. Dutton, Andrea Cherrington, Young-Il Kim, Jeroan J. Allison, and Nefertiti H. Durant

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Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery, Nikolaos Kakouros, Saman Nazarian, Patrizia B. Stadler, Thomas Kickler, and Jeffrey J. Rade

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Seasonal Variations and Trends in Hospitalization for Peptic Ulcer Disease in the United States: A 12-Year Analysis of the Nationwide Inpatient Sample, Ritesh Kanotra, Moiz Ahmed, Nileshkumar Patel, Badal Thakkar, Shantanu Solanki, Sarah Tareen, Matthew J. Fasullo, Mayurathan Kesavan, Nikhil Nalluri, Ahsan Khan, Dhaval Pau, Liliane Deeb, Jeffrey Abergel, and Ananya Das

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Massachusetts Health Reform Cost Less and Was More Effective for Uninsured Individuals With Venous Thromboembolism: A Cost-Effectiveness Analysis, Alok Kapoor, Nicholas Shaffer, Amresh Hanchate, Mark Roberts, and Kenneth Smith

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A Model to Explain How the Bacille Calmette Guerin (BCG) Vaccine Drives Interleukin-12 Production in Neonates, Chido Loveness Kathivu and Daniel H. Libraty

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Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses, Joanna Kawalkowska, Anne-Marie Quirke, Fatemeh Ghari, Simon Davis, Venkataraman Subramanian, Paul R. Thompson, Richard O. Williams, Roman Fischer, Nicholas B. La Thangue, and Patrick J. Venables

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Five-year Safety Data from 5 Clinical Trials of Subcutaneous Golimumab in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis, Jonathan Kay, Roy Fleischmann, Edward Keystone, Elizabeth C. Hsia, Benjamin Hsu, Yiying Zhou, Neil Goldstein, and Jurgen Braun

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NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548, Hao Ke, Limin Zhao, Xu Feng, Haibo Xu, Li Zou, Qin Yang, Xiaosan Su, Lingtao Peng, and Baowei Jiao

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Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012, Nomana M. Khan, Emily S. Jentes, Clive Brown, Pauline Han, Sowmya R. Rao, Phyllis Kozarsky, Stefan H.F. Hagmann, Regina C. LaRocque, Edward T. Ryan, and Global TravEpiNet Consortium (GTEN)

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ChREBP Regulates Fructose-induced Glucose Production Independently of Insulin Signaling, Mi-Sung Kim, Sarah A. Krawczyk, Ludivine Doridot, Alan J. Fowler, Jennifer X. Wang, Sunia A. Trauger, Hye Lim Noh, Hee Joon Kang, John K. Meissen, Matthew Blatnik, Jason K. Kim, Michelle Lai, and Mark A. Herman

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Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study), Darae Ko, David D. McManus, and Michael Rienstra

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Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin, Tomohiro Kubo, Jason Brown, Karl D. Bellve, Branch Craige, Julie M. Craft, Kevin E. Fogarty, Karl-Ferdinand Lechtreck, and George B. Witman (Journal of cell science)

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Impact of Microbiota on Resistance to Ocular Pseudomonas aeruginosa-Induced Keratitis, Abirami Kugadas, Stig Hill Christiansen, Saiprasad Sankaranarayanan, Neeraj K. Surana, Stefanie Gauguet, Ryan Kunz, Raina Fichorova, Thomas Vorup-Jensen, and Mihaela Gadjeva

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"Walking in a maze": community providers' difficulties coordinating health care for homeless patients, Terri LaCoursiere Zucchero, Sarah McDannold, and D. Keith McInnes

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Palliative cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion: current clinical practice or misnomer, Laura A. Lambert and Ariana Harris

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A USP28-53BP1-p53-p21 signaling axis arrests growth after centrosome loss or prolonged mitosis, Bramwell G. Lambrus, Vikas Daggubati, Yumi Uetake, Phillip M. Scott, Kevin M. Clutario, Greenfield Sluder, and Andrew J. Holland (The Journal of cell biology)

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Highlights from the 6th International Meeting on Emerging Diseases and Surveillance (IMED 2016) Vienna, Austria from Nov 3 to 7, 2016, Britta Lassmann and Lawrence C. Madoff

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Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase, Scott E. LeBlanc, Qiong Wu, Pallavi Lamba, Said Sif, and Anthony N. Imbalzano (Nucleic acids research)

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Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation, Jane J. Lee, Kathryn A. Britton, Alison Pedley, Joseph Massaro, Elizabeth K. Speliotes, Joanne M. Murabito, Udo Hoffmann, Cheryl Ingram, John F. Keaney, Ramachandran S. Vasan, and Caroline S. Fox

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Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study, Jane J. Lee, Alison Pedley, Udo Hoffmann, Joseph Massaro, John F. Keaney Jr., Ramachandran S. Vasan, and Caroline S. Fox

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Relationship between Massachusetts Youth Screening Instrument-second version and psychiatric disorders in youths in welfare and juvenile justice institutions in Switzerland, L E. W. Leenarts, C. Dolitzsch, K. Schmeck, J. M. Fegert, Thomas Grisso, and M. Schmid

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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease, Peter L. Lee, Yuefeng Tang, Huawei Li, and David A. Guertin

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Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration, Sang Goo Lee, Mingqian Huang, Nikolaus D. Obholzer, Shan Sun, Wenyan Li, Marco Petrillo, Pu Dai, Yi Zhou, Douglas A. Contanche, Sean G. Megason, Huawei Li, and Zheng-Yi Chen (PloS one)

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CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN, Diana Legarda, Scott J. Justus, Rosalind L. Ang, Nimisha Rikhi, Wenjing Li, Thomas M. Moran, Jianke Zhang, Emiko Mizoguchi, Matija Zelic, Michelle A. Kelliher, J. Magarian Blander, and Adrian T. Ting

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Consensus Paper: Cerebellar Development, Ketty Leto, Baojin Ding, and Daniel Lee Kilpatrick

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External validation of the DHAKA score and comparison with the current IMCI algorithm for the assessment of dehydration in children with diarrhoea: a prospective cohort study, Adam C. Levine, Justin Glavis-Bloom, Payal Modi, Sabiha Nasrin, Bita Atika, Soham Rege, Sarah Robertson, Christopher H. Schmid, and Nur H. Alam

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Access to substance use treatment among young adults who use prescription opioids non-medically, Elliott J. Liebling, Jesse L. Yedinak, Traci C. Green, Scott E. Hadland, Melissa A. Clark, and Brandon D.L. Marshall

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Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland, Guangyuan Li, Isaac N. Hayward, Brittany R. Jenkins, Heather M. Rothfuss, Coleman H. Young, Marja T. Nevalainen, Aaron Muth, Paul R. Thompson, Amy M. Navratil, and Brian D. Cherrington

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Stem cells with a view: a look inside a retinal ciliopathy, Linjing Li and Hemant Khanna

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Autophagy-independent function of Atg1 for apoptosis-induced compensatory proliferation, Mingli Li, Jillian L. Lindblad, Ernesto Perez, Andreas Bergmann, and Yun Fan

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Thirty-day outcomes underestimate endocrine and exocrine insufficiency after pancreatic resection, Pei-Wen Lim, Kate H. Dinh, Mary E. Sullivan, Wahid Y. Wassef, Jaroslav Zivny, Giles F. Whalen, and Jennifer LaFemina

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Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress, Chen Lin, Xinyuan Zhao, Desen Sun, Lingda Zhang, Wenpan Fang, Tingjia Zhu, Qiang Wang, Botao Liu, Saisai Wei, Guangdi Chen, Zhengping Xu, and Xiangwei Gao

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Combining statistics from two national complex surveys to estimate injury rates per hour exposed and variance by activity in the USA, Tin-Chi Lin, Helen R. Marucci-Wellman, Joanna L. Willetts, Melanye J. Brennan, and Santosh K. Verma

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Activation of mTORC1 is essential for beta-adrenergic stimulation of adipose browning, Dianxin Liu, Marica Bordicchia, Chaoying Zhang, Huafeng Fang, Wan Wei, Jian-Liang Li, Adilson L. Guilherme, Kalyani V. P. Guntur, Michael P. Czech, and Sheila Collins

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Implementation and reporting of causal mediation analysis in 2015: a systematic review in epidemiological studies, Shao-Hsien Liu, Christine M. Ulbricht, Stavroula A. Chrysanthopoulou, and Kate L. Lapane

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DNA immunization as a technology platform for monoclonal antibody induction, Shuying Liu, Shixia Wang, and Shan Lu

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Does the Mutant CAG Expansion in Huntingtin mRNA Interfere with Exonucleolytic Cleavage of its First Exon, Wanzhao Liu, Edith L. Pfister, Lori A. Kennington, Kathryn O. Chase, Christian Mueller, Marian DiFiglia, and Neil Aronin

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Preserving Patient Privacy When Sharing Same-Disease Data, Xiaoping Liu, Xiao-Bai Li, Luvai Motiwalla, Wenjun Li, Hua Zheng, and Patricia D. Franklin

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Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy, Y. Lucy Liu, Shaoguang Li, and Peter D. Emanuel

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Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study, Wenyuan Li, John F. Keaney Jr., and Murray A. Mittleman

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DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia, You Li, Hisato Yagi, Gregory M. Hendricks, Gregory J. Pazour, and Cecilia W. Lo

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Coalicion de Salud Comunitaria (COSACO): using a Healthy Community Partnership framework to integrate short-term global health experiences into broader community development, Lawrence C. Loh, Olga Valdman, and Matthew M. Dacso

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Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells, Cecilia Lopez-Sambrooks, Shiteshu Shrimal, Carol Khodier, Daniel P. Flaherty, Natalie Rinis, Jonathan C. Charest, Ningguo Gao, Peng Zhao, Lance Wells, Timothy A. Lewis, Mark A. Lehrman, Reid Gilmore, Jennifer E. Golden, and Joseph N. Contessa

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Ribosome*RelA structures reveal the mechanism of stringent response activation, Anna B. Loveland, Eugene Bah, Rohini Madireddy, Ying Zhang, Axel F. Brilot, Nikolaus Grigorieff, and Andrei A. Korostelev

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Closing the net on retroviruses, Jeremy Luban

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Older Veteran Digital Disparities: Examining the Potential for Solutions Within Social Networks, Tana M. Luger, Timothy P. Hogan, Lorilei M. Richardson, Lisa Cioffari-Bailiff, Kimberly Harvey, and Thomas K. Houston

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The Causes of HIV-Associated Cardiomyopathy: A Tale of Two Worlds, Rebecca H. Lumsden and Gerald S. Bloomfield

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Accurate Prediction of Transposon-Derived piRNAs by Integrating Various Sequential and Physicochemical Features, Longqiang Luo, Dingfang Li, Wen Zhang, Shikui Tu, Xiaopeng Zhu, and Gang Tian

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Safety of anticoagulation with uninterrupted warfarin vs. interrupted dabigatran in patients requiring an implantable cardiac device, Shivanshu Madan, Purushothaman Muthusamy, Katie L. Mowers, Darryl A. Elmouchi, Bohuslav Finta, Andre J. Gauri, Alan K. Woelfel, Timothy D. Fritz, Alan T. Davis, and Nagib T. Chalfoun

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CRISPR-Cas9 nuclear dynamics and target recognition in living cells, Hanhui Ma, Li-Chun Tu, Ardalan Naseri, Maximiliaan Huisman, Shaojie Zhang, David Grünwald, and Thoru Pederson

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Decade Long Trends (2001-2011) in Duration of Pre-Hospital Delay Among Elderly Patients Hospitalized for an Acute Myocardial Infarction, Raghavendra Makam, Nathaniel Erskine, Jorge L. Yarzebski, Darleen M. Lessard, Jason Lau, Jeroan J. Allison, Joel M. Gore, Jerry H. Gurwitz, David D. McManus, and Robert J. Goldberg

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Association between Responsible Pet Ownership and Glycemic Control in Youths with Type 1 Diabetes, Louise Maranda and Olga T. Gupta

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Genomic Access to Monarch Migration Using TALEN and CRISPR/Cas9-Mediated Targeted Mutagenesis, Matthew J. Markert, Ying Zhang, Metewo Selase Enuameh, Steven M. Reppert, Scot A. Wolfe, and Christine Merlin

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Transcriptional Auto-Regulation of RUNX1 P1 Promoter, Milka Martinez, Marcela Hinojosa, Daniel J. Trombly, Violeta Morin, Janet L. Stein, Gary S. Stein, Amjad Javed, and Soraya E. Gutierrez

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The Zn-finger domain of MdmX suppresses cancer progression by promoting genome stability in p53-mutant cells, Zdenka Matijasevic, Anna Krzywicka-Racka, Greenfield Sluder, Judith Gallant, and Stephen N. Jones

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Radial glia regulate vascular patterning around the developing spinal cord, Ryota L. Matsuoka, Michele Marass, Avdesh Avdesh, Christian S.M. Helker, Hans-Martin Maischein, Ann S. Grosse, Harmandeep Kaur, Nathan D. Lawson, Wiebke Herzog, and Didier Y.R. Stainier

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Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting, David Mavor, Benjamin P. Roscoe, Daniel N. Bolon, and James S. Fraser

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T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines, Janet E. McElhaney, George A. Kuchel, Xin Zhou, Susan L. Swain, and Laura Haynes

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Alcohol Consumption, Left Atrial Diameter, and Atrial Fibrillation, David D. McManus, Xiaoyan Yin, Rachel Gladstone, Eric Vittinghoff, Ramachandran S. Vasan, Martin G. Larson, Emelia J. Benjamin, and Gregory M. Marcus

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Early Combination Antiretroviral Therapy Limits Exposure to HIV-1 Replication and Cell-Associated HIV-1 DNA Levels in Infants, Margaret M. McManus, Eric O. Mick, Richard W. Hudson Jr., Lynne M. Mofenson, John L. Sullivan, Mohan Somasundaran, Katherine Luzuriaga, and PACTG 356 Investigators

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A Longitudinal Study of Peripubertal Serum Organochlorine Concentrations and Semen Parameters in Young Men: The Russian Children's Study, Lidia Minguez-Alarcon, Oleg Sergeyev, Jane S. Burns, Paige L. Williams, Mary M. Lee, Susan A. Korrick, Luidmila Smigulina, Boris Revich, and Russ Hauser

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Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function, Parul Mishra, Julia Flynn, Tyler N. Starr, and Daniel N. Bolon

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BRAF and epithelial-mesenchymal transition in papillary thyroid carcinoma - challenging the roles of Snail and E-Cadherin, Brendon Mitchell, Dominick Leone, Shi Yang, Ashraf Khan, Meera Mahalingam, and Jagdish Dhingra

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Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft, Muhammad M. Mohiuddin, Aaron J. Belli, and Keith A. Reimann

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Apontic regulates somatic stem cell numbers in Drosophila testes, Amanda J. Monahan and Michelle Starz-Gaiano

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Dental Calculus Stimulates Interleukin-1beta Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes, Jorge Luis Montenegro Raudales, Atsutoshi Yoshimura, Ziauddin Sm, Takashi Kaneko, Yukio Ozaki, Takashi Ukai, Toshihiro Miyazaki, Eicke Latz, and Yoshitaka Hara

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Border Security: The Role of RIPK3 in Epithelium Homeostasis, Kenta Moriwaki, Sakthi Balaji, and Francis Ka-Ming Chan

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Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury, Jill Moser, Joris van Ark, Marcory C. van Dijk, Dale L. Greiner, Leonard D. Shultz, Harry van Goor, and Jan-Luuk Hillebrands

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State-of-the-art monitoring in treatment of dengue shock syndrome: a case series, Steven L. Moulton, Jane Mulligan, Anon Srikiatkhachorn, Siripen Kalanarooj, Greg Z. Grudic, Sharone Green, Robert V. Gibbons, Gary W. Muniz, Carmen Hinojosa-Laborde, Alan L. Rothman, Stephen J. Thomas, and Victor A. Convertino

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RNA2DNAlign: nucleotide resolution allele asymmetries through quantitative assessment of RNA and DNA paired sequencing data., Mercedeh Movassagh, Nawaf Alomran, Prakriti Mudvari, Merve Dede, Cem Dede, Kamran Kowsari, Paula Restrepo, Edmund Cauley, Sonali Bahl, Muzi Li, Wesley Waterhouse, Krasimira Tsaneva-Atanasova, Nathan Edwards, and Anelia Horvath

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Neoatherosclerosis in Very Late Stenosis of Bare Metal Stent by Optical Coherence Tomography, Samer Mowakeaa, Aline Iskandar, and Nikolaos Kakouros

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Use of orbital atherectomy in acute myocardial infarction via the transradial approach, Samer Mowakeaa, Branden Snyder, and Nikolaos Kakouros

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N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis, Kenan C. Murphy and Carl F. Nathan

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Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper, Derek T. Musashe, Maria D. Purice, Sean D. Speese, Johnna E. Doherty, and Mary A. Logan

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Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine, Masayuki Nagahashi, Toshifumi Wakai, and Stephen R. Lyle

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CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis, Kentaro Nagaoka, K. Fujii, H. Zhang, K. Usuda, G. Watanabe, Maria Ivshina, and Joel D. Richter

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Novel oral transforming growth factor-beta signaling inhibitor EW-7197 eradicates CML-initiating cells, Kazuhito Naka, Shaoguang Li, and Dae-Kee Kim

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Comparative Effectiveness of Etanercept and Adalimumab in Patient Reported Outcomes and Injection-Related Tolerability, Iris Navarro-Millan, Lisa J. Herrinton, Lang Chen, Leslie R. Harrold, Liyan Liu, and Jeffrey R. Curtis

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A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling, Clíona Ní Cheallaigh, Jinhee Lee, Kim West, Nuria Martinez, Hardy Kornfeld, Douglas T. Golenbock, and Ed C. Lavelle

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Clinical expression of facioscapulohumeral muscular dystrophy in carriers of 1-3 D4Z4 reduced alleles: experience of the FSHD Italian National Registry, Ana Nikolic and Rossella Tupler

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Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium, Faye L. Norby and David D. McManus

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SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin, Kentaro Ohkuni, Yoshimitsu Takahashi, Alyona Fulp, Josh Lawrimore, Wei-Chun Au, Nagesh Pasupala, Reuben Levy-Myers, Jack Warren, Alexander Strunnikov, Richard E. Baker, Oliver Kerscher, Kerry Bloom, and Munira A. Basrai