Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2012

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POS-1 and GLD-1 repress glp-1 translation through a conserved binding-site cluster, Brian M. Farley and Sean P. Ryder

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Malignancy validation in a United States registry of rheumatoid arthritis patients, Mark C. Fisher, Victoria Furer, Marc C. Hochberg, Jeffrey D. Greenberg, Joel M. Kremer, Jeffrey R. Curtis, George W. Reed, Leslie R. Harrold, and Daniel H. Solomon

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Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration, Eduardo Gascon and Fen-Biao Gao

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Neuropilin-2 regulates alpha6beta1 integrin in the formation of focal adhesions and signaling, Hira Lal Goel, Bryan M. Pursell, Clive Standley, Kevin E. Fogarty, and Arthur M. Mercurio

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Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue, Maria Paz Gonzalez-Perez, Olivia O'Connell, Rongheng Lin, W. Matthew Sullivan, Jeanne E. Bell, Peter Simmonds, and Paul R. Clapham

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Homologous Recombination Mediates Functional Recovery of Dysferlin Deficiency following AAV5 Gene Transfer, William E. Grose, K. Reed Clark, Danielle Griffin, Vinod Malik, Kimberly M. Shontz, Chrystal L. Montgomery, Sarah Lewis, Robert H. Brown Jr., Paul M. L. Janssen, Jerry R. Mendell, and Louise R. Rodino-Klapac

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Discordant timing between antennae disrupts sun compass orientation in migratory monarch butterflies, Patrick A. Guerra, Christine Merlin, Robert J. Gegear, and Steven M. Reppert

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Patients' knowledge and beliefs concerning gout and its treatment: a population based study, Leslie R. Harrold, Kathleen M. Mazor, Daniel J. Peterson, Nausheen Naz, Cassandra L. Firneno, and Robert A. Yood

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The interrelationship between APC/C and Plk1 activities in centriole disengagement, Toshiyuki Hatano and Greenfield Sluder

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Enhancing medical students' communication skills: development and evaluation of an undergraduate training program, Maria C. Hausberg, Anika herert, Corinna Kroger, Monika Bullinger, Matthias S. F. Rose, and Sylke Andreas

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Self-reported colorectal cancer screening of Medicare beneficiaries in family medicine vs. internal medicine practices in the United States: a cross-sectional study, Angela (Young) Higgins, Anna R. B. Doubeni, Karon L. Phillips, Adeyinka O. Laiyemo, Becky A. Briesacher, Jennifer Tjia, and Chyke A. Doubeni

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Multi-scale motility amplitude associated with suicidal thoughts in major depression, Premananda Indic, Greg Murray, Carlo Maggini, Mario Amore, Tiziana Meschi, Loris Borghi, Ross J. Baldessarini, and Paola Salvatore

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Self-reported adherence with the use of a device in a clinical trial as validated by electronic monitors: the VIBES study, Brianne A. Jeffrey, Marian T. Hannan, Emily K. Quinn, Sheryl Zimmerman, Bruce A. Barton, Clinton T. Rubin, and Douglas P. Kiel

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Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation, Hina Kalra, Vivian Budnik, and Suresh Mathivanan

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An Ounce of Prevention: How Are We Managing the Early Assessment of Residents' Clinical Skills?: A CERA Study, Tracy Kedian, Lisa S. Gussak, Judith A. Savageau, Andreas Cohrssen, Ilene Abramson, Kelly Everard, and Alison Dobbie

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Genetic labeling of neuronal subsets through enhancer trapping in mice, Wolfgang Kelsch, Alberto Stolfi, and Carlos Lois

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Validation of key behaviourally based mental health diagnoses in administrative data: suicide attempt, alcohol abuse, illicit drug abuse and tobacco use, Hyungjin Myra Kim, Eric G. Smith, Claire M. Stano, Dara Ganoczy, Kara Zivin, Heather Walters, and Marcia Valenstein

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Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance, Thomas K. Knott, Pasil A. Madany, Ashley A. Faden, Mei Xu, Jorg Strotmann, Timothy R. Henion, and Gerald A. Schwarting

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Inhibitory control of synaptic and behavioral plasticity by octopaminergic signaling, Alex C. Koon and Vivian Budnik

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Viral infection: an evolving insight into the signal transduction pathways responsible for the innate immune response, Girish J. Kotwal, Steven Hatch, and William L. Marshall

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Cooperativity of Rb, Brca1, and p53 in malignant breast cancer evolution, Prashant Kumar, Malini Mukherjee, Jacob P. S. Johnson, Milan Patel, Bing Huey, Donna G. Albertson, and Karl Simin

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F-box protein specificity for g1 cyclins is dictated by subcellular localization, Benjamin D. Landry, John P. Doyle, David P. Toczyski, and Jennifer A. Benanti

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A new approach to ensuring oral health care for people living with HIV/AIDS: the dental case manager, Celeste A. Lemay, Suzanne B. Cashman, Anne McDonald, and John R. Graves

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Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus, Joseph Lesauter, Christopher M. Lambert, Margaret R. Robotham, Zina Model, Rae Silver, and David R. Weaver

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Intrinsic organization of the anesthetized brain, Zhifeng Liang, Jean A. King, and Nanyin Zhang

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Unique small RNA signatures uncovered in the tammar wallaby genome, James Lindsay, Dawn M. Carone, Judy Brown, Laura Hall, Sohaib Quershi, Sarah E. Mitchell, Nicholas jannetty, Greg Hannon, Marilyn B. Renfree, Andrew J. Pask, Michael O'Neill, and Rachel J. O'Neill

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KAYAK-alpha modulates circadian transcriptional feedback loops in Drosophila pacemaker neurons, Jinli Ling, Raphaelle Dubruille, and Patrick Emery

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Lineage analysis of Drosophila lateral antennal lobe neurons reveals notch-dependent binary temporal fate decisions, Suewei Lin, Chih-Fei Kao, Hung-Hsiang Yu, Ya-ling Huang, and Tzumin Lee

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Coincident generation of pyramidal neurons and protoplasmic astrocytes in neocortical columns, Sanjay Magavi, Drew Friedmann, Garrett Banks, Alberto Stolfi, and Carlos Lois

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Allele- and tir-independent functions of intimin in diverse animal infection models, Emily M. Mallick, Michael J. Brady, Steven A. Luperchio, Vijay K. Vanguri, Loranne Magoun, Hui Liu, Barbara J. Sheppard, Jean Mukherjee, Arthur Donohue-Rolfe, Saul Tzipori, John M. Leong, and David B. Schauer

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A novel murine infection model for Shiga toxin-producing Escherichia coli, Emily M. Mallick, Megan E. McBee, Vijay K. Vanguri, Angela R. Melton-Celsa, Katherine Schlieper, Brad J. Karalius, Alison D. O’Brien, Joan R. Butterton, John M. Leong, and David B. Schauer

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Cellular Signaling Pathways in Alcoholic Liver Disease, Pranoti Mandrekar and Aditya Ambade

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Health effects of the Federal Bureau of Prisons tobacco ban, Stephen A. Martin, Bartolome R. Celli, Joseph R. DiFranza, Stephen J. Krinzman, Jennifer G. Clarke, Herbert Beam, Sandra Howard, Melissa Foster, and Robert J. Goldberg

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Non-canonical TAF complexes regulate active promoters in human embryonic stem cells, Glenn A. Maston, Lihua Julie Zhu, Lynn Chamberlain, Ling Lin, Minggang Fang, and Michael R. Green

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Validity of self-reported height and weight and factors associated with errors in self-report, Anil Chankaramangalam Mathew, Thazhuthekudiyil Sathyan Anithadevi, Rowther Shamna Safar, Singanallur Lakshmanan Ravi Shankar, Moosa Saira Banu, and Yunsheng Ma

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Human Monoclonal Antibody HCV1 Effectively Prevents and Treats HCV Infection in Chimpanzees, Trevor J. Morin, Teresa J. Broering, Brett A. Leav, Barbara M. Blair, Kirk J. Rowley, Elisabeth N. Boucher, Yang Wang, Peter S. Cheslock, Michael Knauber, David B. Olsen, Steve W. Ludmerer, Gyongyi Szabo, Robert W. Finberg, Robert H. Purcell, Robert E. Lanford, Donna M. Ambrosino, Deborah C. Molrine, and Gregory J. Babcock

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An encyclopedia of mouse DNA elements (Mouse ENCODE), Mouse ENCODE Consortium, John A. Stamatoyannopoulos, Michael Snyder, Ross Hardison, Bing Ren, Job Dekker, Bryan R. Lajoie, Gaurav Jain, and Amartya Sanyal

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Sustained miRNA-mediated Knockdown of Mutant AAT With Simultaneous Augmentation of Wild-type AAT Has Minimal Effect on Global Liver miRNA Profiles, Christian Mueller, Qiushi Tang, Alisha Gruntman, Keith S. Blomenkamp, Jeffrey H. Teckman, Lina Song, Phillip D. Zamore, and Terence R. Flotte

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Structural/functional analysis of the human OXR1 protein: identification of exon 8 as the anti-oxidant encoding function, Kenan C. Murphy and Michael R. Volkert

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Treatment of multiple system atrophy using intravenous immunoglobulin, Peter Novak, Arlene Williams, Paula D. Ravin, Omar Zurkiya, Amir Abduljalil, and Vera Novak

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The histone demethylase jhdm1a regulates hepatic gluconeogenesis, Dongning Pan, Chunxiao Mao, Tie Zou, Annie Y. Yao, Marcus P. Cooper, Victor L. Boyartchuk, and Yong-Xu Wang

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Integration of beta-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity, J. Alex Parker, Rafael P. Vazquez-Manrique, Cendrine Tourette, Francesca Farina, Nicolas Offner, Arnab Mukhopadhyay, Anne-Marie Orfila, Aurelie Darbois, Sophie Menet, Heidi A. Tissenbaum, and Christian Neri

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A smartphone-supported weight loss program: design of the ENGAGED randomized controlled trial, Christine A. Pellegrini, Jennifer M. Duncan, Arlen C. Moller, Joanna Buscemi, Alyson Sularz, Andrew DeMott, Alex Pictor, Sherry L. Pagoto, Juned Siddique, and Bonnie J. Spring

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LSK derived LSK- cells have a high apoptotic rate related to survival regulation of hematopoietic and leukemic stem cells, Cong Peng, Yaoyu Chen, Yi Shan, Haojian Zhang, Zhiru Guo, Dongguang Li, and Shaoguang Li

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IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice, Jan Petrasek, Shashi Bala, Timea Csak, Dora Lippai, Karen Kodys, Victoria Menashy, Matthew Barrieau, So-Yun Min, Evelyn A. Kurt-Jones, and Gyongyi Szabo

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The Dynamics of Naturally Acquired Immunity to Plasmodium falciparum Infection, Mykola Pinkevych, Janka Petravic, Kiprotich Chelimo, James W. Kazura, Ann M. Moormann, and Miles P. Davenport

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Data sharing in neuroimaging research, Jean-Baptiste Poline, Janis L. Breeze, Satrajit Ghosh, Krzysztof Gorgolewski, Yaroslav O. Halchenko, Michael Hanke, Christian Haselgrove, Karl G. Helmer, David B. Keator, Daniel S. Marcus, Russell A. Poldrack, Yannick Schwartz, John Ashburner, and David N. Kennedy

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Stat5 Signaling Specifies Basal versus Stress Erythropoietic Responses through Distinct Binary and Graded Dynamic Modalities, Ermelinda Porpiglia, Daniel Hidalgo, Miroslav Koulnis, Abraham R. Tzafriri, and Merav Socolovsky

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A key role for chd1 in histone h3 dynamics at the 3' ends of long genes in yeast, Marta Radman-Livaja, Tiffani K. Quan, Lourdes Valenzuela, Jennifer A. Armstrong, Tibor van Welsem, Tae Soo Kim, Laura J. Lee, Stephen Buratowski, Fred van Leeuwen, Oliver J. Rando, and Grant A. Hartzog

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Defective pro-IL-1beta responses in macrophages from aged mice, Alejandor Ramirez, Vijay A. K. Rathinam, Katherine A. Fitzgerald, Douglas T. Golenbock, and Anuja Mathew

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Association of acculturation and country of origin with self-reported hypertension and diabetes in a heterogeneous Hispanic population, Fatima Rodriguez, LeRoi S. Hicks, and Lenny Lopez

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The classical pink-eyed dilution mutation affects angiogenic responsiveness, Michael S. Rogers, Victor L. Boyartchuk, Richard M. Rohan, Amy E. Birsner, William F. Dietrich, and Robert J. D'Amato

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The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors, Keith P. Romano, Akbar Ali, Cihan Aydin, Djade Soumana, Aysegul Ozen, Laura M. Deveau, Casey Silver, Hong Cao, Alicia Newton, Christos J. Petropoulos, Wei Huang, and Celia A. Schiffer

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Design and Methods for a Comparative Effectiveness Pilot Study: Virtual World vs. Face-to-Face Diabetes Self-Management, Milagros C. Rosal, Robin Heyden, Roanne Mejilla, Maria Rizzo Depaoli, Chetty Veerappa, and John M. Wiecha

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Increase in the proportion of patients hospitalized with acute myocardial infarction with do-not-resuscitate orders already in place between 2001 and 2007: a nonconcurrent prospective study, Jane S. Saczynski, Ezra Gabbay, David D. McManus, Richard H. McManus, Joel M. Gore, Jerry H. Gurwitz, Darleen M. Lessard, and Robert J. Goldberg

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HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency, Federico A. Santoni, Jessica Guerra, and Jeremy Luban

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Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans, Jennifer A. Schumacher, Yi-Wen Hsieh, Shiuhwei Chen, Jennifer K. Pirri, Mark J. Alkema, Wen-hong Li, Chieh Chang, and Chiou-Fen Chuang

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Wandering neuronal migration in the postnatal vertebrate forebrain, Benjamin B. Scott, Timothy Gardner, Ni Ji, Michale S. Fee, and Carlos Lois

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Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study, Amir Y. Shaikh, Abhishek Mann, Umar A. Khan, Gerard P. Aurigemma, Jeffrey C. Hill, Jennifer L. Kane, Dennis A. Tighe, Eric Mick, and David D. McManus

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Human-specific histone methylation signatures at transcription start sites in prefrontal neurons, Hennady P. Shulha, Jessica L. Crisci, Denis Reshetov, Jogender S. Tushir, Iris Cheung, Rahul Bharadwaj, Hsin-Jung Chou, Isaac B. Houston, Cyril J. Peter, Amanda C. Mitchell, Wei-Dong Yao, Richard H. Myers, Jiang-Fan Chen, Todd M. Preuss, Evgeny I. Rogaev, Jeffrey D. Jensen, Zhiping Weng, and Schahram Akbarian

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Assessing Oral Health Curriculum in US Family Medicine Residency Programs: A CERA Study, Hugh Silk, Ronnelle King, Ian M. Bennett, Alexander W. Chessman, and Judith A. Savageau

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Recurrent Plasmodium falciparum malaria infections in Kenyan children diminish T-cell immunity to Epstein Barr virus lytic but not latent antigens, Cynthia J. Snider, Stephen R. Cole, Kiprotich Chelimo, Peter Odada Sumba, Pia D. M. Macdonald, Chandy C. John, Steven R. Meshnick, and Ann M. Moormann

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CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2, Roy J. Soberman, Christopher R. MacKay, Christine A. Vaine, Glennice Bowen Ryan, Anna M. Cerny, Mikayla R. Thompson, Boris Nikolic, Valeria Primo, Peter Christmas, Paul Sheiffele, Lisa Aronov, David M. Knipe, and Evelyn A. Kurt-Jones

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Glucan particles for macrophage targeted delivery of nanoparticles, Ernest Soto, Abaigeal C. Caras, Lindsey C. Kut, Melissa K. Castle, and Gary R. Ostroff

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Dengue viral RNA levels in peripheral blood mononuclear cells are associated with disease severity and preexisting dengue immune status, Anon Srikiatkhachorn, Sineewanlaya Wichit, Robert V. Gibbons, Sharone Green, Daniel H. Libraty, Timothy P. Endy, Francis A. Ennis, Siripen Kalayanarooj, and Alan L. Rothman

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C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1, Chiranthani Sumanasekera, Olga Kelemen, Monique Beullens, Brandon E. Aubol, Joseph A. Adams, Manjula Sunkara, Andrew Morris, Mathieu Bollen, Athena Andreadis, and Stefan Stamm

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A fast and sensitive alternative for beta-galactosidase detection in mouse embryos, Sakthi Sundararajan, Maki Wakamiya, Richard R. Behringer, and Jaime A. Rivera-Perez

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Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants, Kailiang Sun, Jakub Orzechowski Westholm, Kazuya Tsurudome, Joshua W Hagen, Yubing Lu, Minoree Kohwi, Doron Betel, Fen-Biao Gao, A. Pejmun Haghighi, Chris Q. Doe, and Eric C. Lai

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Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells, Manish Tandon, Karthiga Devi Gokul, Syed A. Ali, Zujian Chen, Jane B. Lian, Gary S. Stein, and Jitesh Pratap

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Smoking, cardiac symptoms, and an emergency care visit: a mixed methods exploration of cognitive and emotional reactions, Karyn A. Tappe, Edwin D. Boudreaux, Beth Bock, Erin L. O'Hea, Brigitte M. Baumann, Steven Hollenberg, Bruce M. Becker, and Gretchen B. Chapman

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Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress, Andrea R. Tentner, Michael J. Lee, Gerry J. Ostheimer, Leona D. Samson, Douglas A. Lauffenburger, and Michael B. Yaffe

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The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells, Anna J. Ucher, Erin K. Linehan, George W. Teebor, Carol E. Schrader, and Janet Stavnezer

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Host-pathogen interactions of retroviruses, Abdul A. Waheed, Abraham L. Brass, Suryaram Gummuluru, and Gilda Tachedjian

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Plasmacytoid dendritic cell interferon-alpha production to R-848 stimulation is decreased in male infants, Jennifer P. Wang, Lei Zhang, Rachel F. Madera, Marcia Woda, and Daniel H. Libraty

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The Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials, Charles Weijer, Jeremy M. Grimshaw, Martin P. Eccles, Andrew D. McRae, Angela White, Jamie C. Brehaut, Monica Taljaard, Ottawa Ethics of Cluster Randomized Trials Consensus Group, and Catarina I. Kiefe

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Type 1 interferons and antiviral CD8 T-cell responses, Raymond M. Welsh, Kapil Bahl, Heather D. Marshall, and Stina L. Urban

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Functional analysis of transcription factor binding sites in human promoters, Troy W. Whitfield, Jie Wang, Patrick J. Collins, E. Christopher Partridge, Shelley Force Aldred, Nathan D. Trinklein, Richard M. Myers, and Zhiping Weng

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Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo, Thomas M. Wishart, Timothy M. Rooney, Douglas J. Lamont, Ann K. Wright, A. Jennifer Morgon, Mandy Jackson, Marc R. Freeman, and Thomas H. Gillingwater

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Mullerian Inhibiting Substance Recruits ALK3 to Regulate Leydig Cell Differentiation, Xiufeng Wu, Ningning Zhang, and Mary M. Lee

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FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response, Jenny X. Xie, Min Peng, Shawna Guillemette, Steven Quan, Stephanie Maniatis, Yuliang Wu, Aditya Venkatesh, Scott A. Shaffer, Robert M. Brosh Jr., and Sharon B. Cantor

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A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells, Li Xie, Claude Gazin, Sung Mi Park, Lihua Julie Zhu, Marie-Anne Debily, Ellen L. W. Kittler, Maria L. Zapp, David S. Lapointe, Stephane Gobeil, Ching-Man A. Virbasius, and Michael R. Green

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Genome-wide identification and characterization of replication origins by deep sequencing, Jia Xu, Yoshimi Yanagisawa, Alexander M. Tsankov, Christopher Hart, Keita Aoki, Naveen Kommajosyula, Kathleen E. Steinmann, James Bochicchio, Carsten Russ, Aviv Regev, Oliver J. Rando, Chad Nusbaum, Hironori Niki, Patrice Milos, Zhiping Weng, and Nicholas R. Rhind

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Bleomycin sensitivity in Escherichia coli is medium-dependent, Tao Xu, William Brown, and Martin G. Marinus

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Does a loss of TDP-43 function cause neurodegeneration, Zuoshang Xu

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Modeling formamide denaturation of probe-target hybrids for improved microarray probe design in microbial diagnostics, L. Safak Yilmaz, Alexander Loy, Erik S. Wright, Michael Wagner, and Daniel R. Noguera

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CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone, James L. Young, Alfonso Mora, Anna M. Cerny, Michael P. Czech, Bruce A. Woda, Evelyn A. Kurt-Jones, Robert W. Finberg, and Silvia Corvera

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RNA: methods and protocols - a new series, Phillip D. Zamore

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Scd1 plays a tumor-suppressive role in survival of leukemia stem cells and the development of chronic myeloid leukemia, Haojian Zhang, Huawei Li, Ngoc Ho, Dongguang Li, and Shaoguang Li

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Chondrolectin mediates growth cone interactions of motor axons with an intermediate target, Zhen Zhong, Jochen Ohnmacht, Michell M. Reimer, Ingolf Bach, Thomas C. Becker, and Catherina G. Becker

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Integrative gene regulatory network analysis reveals light-induced regional gene expression phase shift programs in the mouse suprachiasmatic nucleus, Haisun Zhu, Rajanikanth Vadigepalli, Rachel Rafferty, Gregory E. Gonye, David R. Weaver, and James S. Schwaber

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PU.1 Is Essential for CD11c Expression in CD8(+)/CD8(-) Lymphoid and Monocyte-Derived Dendritic Cells during GM-CSF or FLT3L-Induced Differentiation, Xue-Jun Zhu, Zhongfa Yang, Yaoyu Chen, Junling Wang, and Alan G. Rosmarin

Publications from 2011

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Genomics in 2011: challenges and opportunities, David J. Adams, Bonnie Berger, Olivier Harismendy, Curtis Huttenhower, X. Shirley Liu, Chad L. Myers, Alicia Oshlack, John L. Rinn, and Albertha J. M. Walhout

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Progranulin, a glycoprotein deficient in frontotemporal dementia, is a novel substrate of several protein disulfide isomerase family proteins, Sandra Almeida, Lijuan Zhou, and Fen-Biao Gao

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Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins, Stefan L. Ameres, Jui-Hung Hung, Jia Xu, Zhiping Weng, and Phillip D. Zamore

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PPARdelta Regulates Satellite Cell Proliferation and Skeletal Muscle Regeneration, Alison R. Angione, Chunhui Jiang, Dongning Pan, Yong-Xu Wang, and Shihuan Kuang

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Loss of p53 Ser18 and Atm results in embryonic lethality without cooperation in tumorigenesis, Heather L. Armata, Punita Shroff, David S. Garlick, Krista L. Penta, Andrew R. Tapper, and Hayla Karen Sluss

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Metabolic regulation of mycobacterial growth and antibiotic sensitivity, Seung-Hun Baek, Alice H. Li, and Christopher M. Sassetti

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Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence, Eugene Berezikov, Nicolas Robine, Anastasia Samsonova, Jakub Orzechowski Westholm, Ammar Naqvi, Jui-Hung Hung, Katsutomo Okamura, Qi Dai, Diane Bortolamiol-Becet, Raquel Martin, Yongjun Zhao, Phillip D. Zamore, Gregory J. Hannon, Marco A. Marra, Zhiping Weng, Norbert Perrimon, and Eric C. Lai

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Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons, Michael J. Bianchetta, TuKiet T. Lam, Stephen N. Jones, and Maria A. Morabito

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Host genetic risk factors for West Nile virus infection and disease progression, Abigail W. Bigham, Kati J. Buckingham, Sofia Husain, Mary J. Edmond, Kathryn M. Bofferding, Heidi Gildersleeve, Ann Rutherford, Natalia M. Astakhova, Andrey A. Perelygin, Michael P. Busch, Kristy O. Murray, James J. Sejvar, Sharone Green, John Kriesel, Margo A. Brinton, and Michael Bamshad