Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2017

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Beta-Blocker Use Is Associated With Impaired Left Atrial Function in Hypertension, Mayank Sardana, Amer Ahmed Syed, Zeba Hashmath, Timothy S. Phan, Maheswara R. Koppula, Uzma Kewan, Zoubair Ahmed, Ravikantha Chandamuri, Swapna Varakantam, Ejaz Shah, Ryan Gorz, Scott R. Akers, and Julio A. Chirinos

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Long-term cardiovascular mortality after radiotherapy for breast cancer: A systematic review and meta-analysis, Partha Sardar, Amartya Kundu, Saurav Chatterjee, Anju Nohria, Ramez Nairooz, Sripal Bangalore, Debabrata Mukherjee, Wilbert S. Aronow, and Carl J. Lavie

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Patient safety during procedural sedation using capnography monitoring: a systematic review and meta-analysis, Rhodri Saunders, Michel M.R.F. Struys, Richard F. Pollock, Michael Mestek, and Jenifer R. Lightdale

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miRNAs cooperate in apoptosis regulation during C. elegans development, Ryan Sherrard, Sebastian Luehr, Heinke Holzkamp, Katherine McJunkin, Nadin Memar, and Barbara Conradt

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Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY, Jade Shi, R Paul. Nobrega, Christian Schwantes, Sagar V. Kathuria, Osman Bilsel, C. Robert Matthews, T J. Lane, and Vijay S. Pande

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Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer, Yoshifumi Shimada, Stephen Lyle, and Toshifumi Wakai

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When Breath Becomes Air [book review], Hugh Silk

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Prevalence of, and Resident and Facility Characteristics Associated With Antipsychotic Use in Assisted Living vs. Long-Term Care Facilities: A Cross-Sectional Analysis from Alberta, Canada, Kathryn J. Stock, Joseph E. Amuah, Kate L. Lapane, David B. Hogan, and Colleen J. Maxwell

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Child contact management in high tuberculosis burden countries: A mixed-methods systematic review, Daria Szkwarko, Yael Hirsch-Moverman, Lienki Du Plessis, Karen Du Preez, Catherine W. Carr, and Anna M. Mandalakas

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Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein, Maoxue Tang, Guangping Gao, Huapeng Li, Qin Su, Darryl C. De Vivo, and Umrao R. Monani

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Risk of Gastrointestinal Bleeding Among Dabigatran Users - A Self Controlled Case Series Analysis, Wenze Tang, Hsien-Yen Chang, Meijia Zhou, and Sonal Singh

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Circumstances of fall-related injuries by age and gender among community-dwelling adults in the United States, Lava R. Timsina, Joanna L. Willetts, Melanye J. Brennan, Helen Marucci-Wellman, David A. Lombardi, Theodore K. Courtney, and Santosh K. Verma

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Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring, Markus P. Vallaster, Shweta Kukreja, Xin Y. Bing, Jennifer Ngolab, Rubing Zhao-Shea, Paul D. Gardner, Andrew R. Tapper, and Oliver J. Rando

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Humanized Mouse Models of Clinical Disease, Nicole C. Walsh, Laurie L. Kenney, Sonal Jangalwe, Ken-Edwin Aryee, Dale L. Greiner, Michael A. Brehm, and Leonard D. Shultz

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Microvascular response to transfusion in elective spine surgery, J. Matthias Walz, Ottokar Stundner, Federico P. Girardi, Bruce A. Barton, Aimee R. Kroll-Desrosiers, Stephen O. Heard, and Stavros G. Memtsoudis

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Resting-state functional connectivity changes within the default mode network and the salience network after antipsychotic treatment in early-phase schizophrenia, Yingchan Wang, Weijun Tang, Xiaoduo Fan, Jianye Zhang, Daoying Geng, Kaida Jiang, Dianming Zhu, Zhenhua Song, Zeping Xiao, and Dengtang Liu

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Metformin inhibits the proliferation of benign prostatic epithelial cells, Zongwei Wang, Xingyuan Xiao, Rongbin Ge, Jijun Li, Cameron W. Johnson, Cyrus Rassoulian, and Aria F. Olumi

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Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis, Hai Wu, Jonathan A. Gordon R, Troy W. Whitfield, Phillip W. Tai L, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian

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Altered resting-state intra- and inter- network functional connectivity in patients with persistent somatoform pain disorder, Zhiyong Zhao, Tianming Huang, Chaozheng Tang, Kaiji Ni, Xiandi Pan, Chao Yan, Xiaoduo Fan, Dongrong Xu, and Yanli Luo

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Readability Formulas and User Perceptions of Electronic Health Records Difficulty: A Corpus Study, Jiaping Zheng and Hong Yu

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GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases, Lihua Julie Zhu, Michael Lawrence, Ankit Gupta, Herve Pages, Alper Kucukural, Manuel Garber, and Scot A. Wolfe

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Vibrotactile stimulation: A non-pharmacological intervention for opioid-exposed newborns, Ian Zuzarte, Premananda Indic, Bruce A. Barton, David Paydarfar, Francis Bednarek, and Elisabeth B. Salisbury

Publications from 2016

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Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome, Priyanka D. Abeyrathne, Cha San Koh, Timothy Grant, Nikolaus Grigorieff, and Andrei A. Korostelev

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Persistent Low-Level Replication of SIVDeltanef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection, Sama Adnan, Wenjun Li, and R. Paul Johnson

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A Modular Assembly Platform for Rapid Generation of DNA Constructs, Elliot Akama-Garren, Nik Joshi, Tuomas Tammela, Gregory P. Chang, Bethany L. Wagner, Da-Yae Lee, William M. Rideout Iii, Thales Papagiannakopoulos, Wen Xue, and Tyler Jacks

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The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity, Samer G. Alam, Qiao Zhang, Nripesh Prasad, Yuan Li, Srikar Chamala, Ram Kuchibhotla, Birendra Kc, Varun Aggarwal, Shristi Shrestha, Angela L. Jones, Shawn E. Levy, Kyle J. Roux, Jeffrey A. Nickerson, and Tanmay P. Lele

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Auditory Hallucinations and the Brain's Resting-State Networks: Findings and Methodological Observations, Ben Alderson-Day, Kelly Diederen, Charles Fernyhough, Judith M. Ford, Guillermo Horga, Daniel S. Margulies, Simon McCarthy-Jones, Georg Northoff, James M. Shine, Jessica Turner, Vincent van de Ven, Remko van Lutterveld, Flavie Waters, and Renaud Jardri

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Incidence of Dengue Virus Infection in Adults and Children in a Prospective Longitudinal Cohort in the Philippines, Maria Theresa Alera, Anon Srikiatkhachorn, John Mark Velasco, Ilya A. Tac-An, Catherine B. Lago, Hannah Clapham, Stefan Fernandez, Jens W. Levy, Butsaya Thaisomboonsuk, Chonticha Klungthong, Louis R. Macareo, Ananda Nisalak, Laura L. Hermann, Daisy Villa, and In-Kyu Yoon

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Culturally adaptive storytelling method to improve hypertension control in Vietnam - "We talk about our hypertension": study protocol for a feasibility cluster-randomized controlled trial, Jeroan J. Allison, Hoa L. Nguyen, Duc A. Ha, German A. Pihan, Ha N. Ly, Hanh T. Tran, Ngoc T. Phan, Nguyen C. Vu, Minjin Kim, and Robert J. Goldberg

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Examination of Huntington's disease with atypical clinical features in a Bangladeshi family tree, Md Mahfuz Al-Mamun, Suprovath Kumar Sarker, Syeda Kashfi Qadri, Tahmina Shirin, Quazi Deen Mohammad, Regina LaRocque, Elinor K. Karlsson, Narayan Saha, Muhammad Asaduzzaman, Firdausi Qadri, and Md Kaiissar Mannoor

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Glucose Metabolism Disorder Is Associated with Pulmonary Tuberculosis in Individuals with Respiratory Symptoms from Brazil, Jilson L. Almeida-Junior, Leonardo Gil-Santana, Carolina A.M. Oliveira, Simone Castro, Aparecida S. Cafezeiro, Carla Daltro, Eduardo M. Netto, Hardy Kornfeld, and Bruno B. Andrade

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Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease, Aditya Ambade, Abhishek Satishchandran, Benedek Gyongyosi, Patrick Lowe, and Gyongyi Szabo

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Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1alpha activation, Aditya Ambade, Abhishek Satishchandran, and Gyongyi Szabo

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Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4, Warrison A. Andrade, Sarika Agarwal, Shunyan Mo, Scott A. Shaffer, Joseph P. Dillard, Tobias Schmidt, Veit Hornung, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, and Douglas T. Golenbock

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Whole exome sequencing links dental tumor to an autosomal-dominant mutation in ANO5 gene associated with gnathodiaphyseal dysplasia and muscle dystrophies, T. V. Andreeva, T. V. Tyazhelova, V. N. Rykalina, F. E. Gusev, Andrey Y. Goltsov, O. I. Zolotareva, M. P. Aliseichik, T. A. Borodina, Anastasia P. Grigorenko, Denis Reshetov, E. K. Ginter, S. S. Amelina, R A. Zinchenko, and Evgeny I. Rogaev

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Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation, Eugenie Ansseau, Jocelyn O. Eidahl, Celine Lancelot, Alexandra Tassin, Christel Matteotti, Cassandre Yip, Jian Liu, Baptiste Leroy, Celine Hubeau, Cecile Gerbaux, Samuel Cloet, Armelle Wauters, Sabrina Zorbo, Pierre Meyer, Isabelle Pirson, Dalila Laoudj-Chenivesse, Ruddy Wattiez, Scott Q. Harper, Alexandra Belayew, and Frederique Coppee

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In vivo correction of anaemia in beta-thalassemic mice by gammaPNA-mediated gene editing with nanoparticle delivery, Raman Bahal, Dale L. Greiner, Michael A. Brehm, and Peter M. Glazer

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Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation, Mandar Bawadekar, Annette Gendron-Fitzpatrick, Ryan Rebernick, Daeun Shim, Thomas F. Warner, Anthony P. Nicholas, Lennart K. Lundblad A, Paul R. Thompson, and Miriam A. Shelef

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Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer, Marc A. Becker, Yasir H. Ibrahim, Annabell S. Oh, Dedra H. Fagan, Sara A. Byron, Aaron L. Sarver, Adrian V. Lee, Leslie M. Shaw, Cheng Fan, Charles M. Perou, and Douglas Yee

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microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration, Surjyadipta Bhattacharjee, Yuhai Zhao, Prerna Dua, Evgeny I. Rogaev, and Walter J. Lukiw

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Depression treatment decreases healthcare expenditures among working age patients with comorbid conditions and type 2 diabetes mellitus along with newly-diagnosed depression, Rituparna Bhattacharya, Chan Shen, Amy B. Wachholtz, Nilanjana Dwibedi, and Usha Sambamthoori

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MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations, Md Helal Uddin Biswas, Sandra Almeida, Rodrigo Lopez-Gonzalez, Wenjie Mao, Zhijun Zhang, Anna M. Karydas, Michael D. Geschwind, Jacek Biernat, Eva-Maria Mandelkow, Kensuke Futai, Bruce L. Miller, and Fen-Biao Gao

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Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses, Austin W. Boesch, Aaron J. Belli, Keith A. Reimann, and Margaret E. Ackerman

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Childhood traumatic experiences and mental health problems in sexually offending and non-sexually offending juveniles, Cyril Boonmann, Thomas Grisso, Laura S. Guy, Olivier F. Colins, Eva A. Mulder, P. Vahl, Lucres M. C. Jansen, Theo A. Doreleijers H, and Robert R. J. M. Vermeiren

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IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection, Matthew G. Booty, Palmira Barreira-Silva, Stephen Carpenter, Claudio Nunes-Alves, Miye K. Jacques, Britni L. Stowell, Pushpalatha Jayaraman, Gillian Beamer, and Samuel M. Behar

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Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates, Florie Borel, Gwladys Gernoux, Brynn Cardozo, Jake P. Metterville, Gabriela Toro Cabrera, Lina Song, Qin Su, Guang Ping Gao, Mai K. Elmallah, Robert H. Brown Jr., and Christian Mueller

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Corrigendum: FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons, Carles Bosch, Albert Martinez, Nuria Masachs, Catia M. Teixeira, Isabel Fernaud, Fausto Ulloa, Esther Perez-Martinez, Carlos Lois, Joan X. Comella, Javier DeFelipe, Angel Merchan-Perez, and Eduardo Soriano

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Implementation of a Computerized Screening Inventory: Improved Usability Through Iterative Testing and Modification, Edwin D. Boudreaux, Andrew Christopher Fischer, Brianna Haskins, Zubair Saeed Zafar, Guanling Chen, and Sneha A. Chinai

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A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis, Cara C. Boutte, Christina E. Baer, Kadamba Papavinasasundaram, Weiru Liu, Michael R. Chase, Xavier Meniche, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger, and Eric J. Rubin

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The Effect of Parathion on Red Blood Cell Acetylcholinesterase in the Wistar Rat, Naofumi Bunya, Keigo Sawamoto, Hanif Benoit, and Steven B. Bird

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Associations of Peripubertal Serum Dioxin and Polychlorinated Biphenyl Concentrations with Pubertal Timing among Russian Boys, Jane S. Burns, Mary M. Lee, Paige L. Williams, Susan A. Korrick, Oleg Sergeyev, Thuy Lam, Boris Revich, and Russ Hauser (Environmental health perspectives)

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xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation, Yi Cai, Subhalaxmi Nambi, Christopher M. Sassetti, Fudi Wang, and Xinchun Chen

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A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes, Michelle A. Carmell, Gregoriy A. Dokshin, Helen Skaletsky, Yueh-Chiang Hu, Josien C. van Wolfswinkel, Kyomi J. Igarashi, Daniel W. Bellott, Michael Nefedov, Peter W. Reddien, George C. Enders, Vladimir N. Uversky, Craig C. Mello, and David C. Page

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A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis, Stephen M. Carpenter, Claudio Nunes-Alves, Matthew G. Booty, Sing Sing Way, and Samuel M. Behar

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ASM Journals Eliminate Impact Factor Information from Journal Websites, Arturo Casadevall, Roger J. Davis, and ASM Journal Editors and Leadership

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A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22, Hui-Hsin Chang, Paul R. Thompson, and I-Cheng Ho

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Drosophila Vision Depends on Carcinine Uptake by an Organic Cation Transporter, Ratna Chaturvedi, Zhuo Luan, Peiyi Guo, and Hong-Sheng Li

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NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection, Satyanarayana Swamy Cheekatla, Deepak Tripathi, Sambasivan Venkatasubramanian, Pavan Kumar Nathella, Padmaja Paidipally, Munenori Ishibashi, Elwyn Welch, Amy R. Tvinnereim, Mitsuo Ikebe, Vijaya Lakshmi Valluri, Subash Babu, Hardy Kornfeld, and Ramakrishna Vankayalapati

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Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans, Hilary K. Cheesman, Rhonda Feinbaum, Jose Thekkiniath, Robert H. Dowen, Annie L. Conery, and Read Pukkila-Worley

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Decade-long trends in the timeliness of receipt of a primary percutaneous coronary intervention, Han-Yang Chen, Joel M. Gore, Kate L. Lapane, Jorge L. Yarzebski, Sharina D. Person, Catarina I. Kiefe, and Robert J. Goldberg

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Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs, Jenny Chen, Alexander A. Shishkin, Xiaopeng Zhu, Sabah Kadri, Itay Maza, Mitchell Guttman, Jacob H. Hanna, Aviv Regev, and Manuel Garber

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Finding Important Terms for Patients in Their Electronic Health Records: A Learning-to-Rank Approach Using Expert Annotations, Jinying Chen, Jiaping Zheng, and Hong Yu

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HIV-1 capsid is involved in post-nuclear entry steps, Nan-Yu Chen, Lihong Zhou, Paul J. Gane, Silvana Opp, Neil J. Ball, Giuseppe Nicastro, Madeleine Zufferey, Cindy Buffone, Jeremy Luban, David Selwood, Felipe Diaz-Griffero, Ian Taylor, and Ariberto Fassati

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CA19-9 decrease at 8 weeks as a predictor of overall survival in a randomized phase III trial (MPACT) of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone in patients with metastatic pancreatic cancer, Gabriela E. Chiorean and Venu G. Bathini

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CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses, Shu Zhen Chong, Maximilien Evrard, John E. Harris, and Lai Guan Ng

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Long-term activation of the innate immune system in atherosclerosis, Anette Christ, Siroon Bekkering, Eicke Latz, and Niels P. Riksen

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Levels of physical dependence on tobacco among adolescent smokers in Cyprus, Costas A. Christophi, Despina Pampaka, Martha Paisi, Solonas Ioannou, and Joseph R. DiFranza

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Access to New Medications for Hepatitis C for Medicaid Members: A Retrospective Cohort Study, Karen M. Clements, Robin E. Clark, Pavel Lavitas, Parag Kunte, Camilla S. Graham, Elizabeth O'Connell, Kimberly J. Lenz, and Paul Jeffrey

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Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression, Beatriz Araujo Cortez, Paula Rezende-Teixeira, Sambra D. Redick, Stephen J. Doxsey, and Glaucia Maria Machado-Santelli

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Diagnostic Prevalence of Ankylosing Spondylitis Using Computerized Health Care Data, 1996 to 2009: Underrecognition in a US Health Care Setting, Jeffrey R. Curtis, Leslie R. Harrold, Maryam M. Asgari, Atul Deodhar, Craig Salman, Joel M. Gelfand, Jashin J. Wu, and Lisa J. Herrinton

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Health Information Brokers in the General Population: An Analysis of the Health Information National Trends Survey 2013-2014, Sarah L. Cutrona, Kathleen M. Mazor, Amenah A. Agunwamba, Sruthi Valluri, Patrick M. Wilson, Rajani S. Sadasivam, and Lila J. Finney Rutten

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Improving Rates of Influenza Vaccination Through Electronic Health Record Portal Messages, Interactive Voice Recognition Calls and Patient-Enabled Electronic Health Record Updates: Protocol for a Randomized Controlled Trial, Sarah L. Cutrona, Meera Sreedhara, Sarah L. Goff, Lloyd D. Fisher, Peggy Preusse, Madeline Jackson, Devi Sundaresan, Lawrence D. Garber, and Kathleen M. Mazor

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Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance, Sezin Dagdeviren, Dae Young Jung, Eunjung Lee, Randall H. Friedline, Hye Lim Noh, Jong Hun. Kim, Payal R. Patel, Nicholas Tsitsilianos, Andrew V. Tsitsilianos, Duy A. Tran, George H. Tsougranis, Caitlyn C. Kearns, Cecilia P. Uong, Jung Yeon. Kwon, Werner Muller, Ki Won. Lee, and Jason K. Kim

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Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS, Jesse D. Deere, W L. Chang William, Luis D. Castillo, Kim A. Schmidt, Hung T. Kieu, Nicholas Renzette, Timothy F. Kowalik, Stephen W. Barthold, Barbara L. Shacklett, Peter A. Barry, and Ellen E. Sparger

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Prevalence, Predictors, and Same Day Treatment of Positive VIA Enhanced by Digital Cervicography and Histopathology Results in a Cervical Cancer Prevention Program in Cameroon, Geneva A. DeGregorio, Leslie Bradford, Rebecca Kemunto Ogembo, Yuxin Liu, and Javier Gordon Ogembo

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Crave-Out: A Distraction/Motivation Mobile Game to Assist in Smoking Cessation, Kathryn Delaughter, Rajani S. Sadasivam, Ariana Kamberi, Thomas M. English, Gregory Seward, S. Wayne Chan, Julie E. Volkman, Daniel J. Amante, and Thomas K. Houston

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The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins, Alexey Dementiev, Anand Sitaram, Yan Hu, Raffi V. Aroian, and Colin Berry

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End Sequence Analysis ToolKit (ESAT) expands the extractable from single cell RNA-seq experiments, Alan G. Derr, Chaoxing Yang, Rapolas Zilionis, Alexey Sergushichev, David Blodgett, Sambra D. Redick, Rita Bortell, Jeremy Luban, David Harlan, Sebastian Kadener, Dale L. Greiner, Allon Klein, Maxim Artyomov, and Manuel Garber

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New Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for Influenza, Priyadharshini Devarajan, Bianca L. Bautista, Allen M. Vong, K. Kai McKinstry, Tara M. Strutt, and Susan L. Swain

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Performance of the G4 Xpert(R) MTB/RIF assay for the detection of Mycobacterium tuberculosis and rifampin resistance: a retrospective case-control study of analytical and clinical samples from high- and low-tuberculosis prevalence settings, Nila J. Dharan, Robert Blakemore, Alexander Sloutsky, Devinder Kaur, Richard C. Alexander, Minoo Ghajar, Kimberlee A. Musser, Vincent E. Escuyer, Marie-Claire Rowlinson, Susanne Crowe, Rafael Laniado-Laborin, Eloise Valli, Pamela Nabeta, Pamela Johnson, and David Alland

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Can tobacco dependence provide insights into other drug addictions, Joseph R. DiFranza

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Reciprocal autoregulation by NFI occupancy and ETV1 promotes the developmental expression of dendrite-synapse genes in cerebellar granule neurons, Baojin Ding, John W. Cave, Paul R. Dobner, Debra Mullikin-Kilpatrick, Marina Bartzokis, Hong Zhu, Chi-Wing Chow, Richard M. Gronostajski, and Daniel Lee Kilpatrick

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Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance, Marina DiStefano, Rachel J. Roth Flach, Ozlem Senol-Cosar, Laura V. Danai, Joseph V. Virbasius, Sarah M. Nicoloro, Juerg R. Straubhaar, Sezin Dagdeviren, Martin Wabitsch, Olga T. Gupta, Jason K. Kim, and Michael P. Czech

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The beneficial role of extracellular reactive oxygen species in apoptosis-induced compensatory proliferation, Neha Diwanji and Andreas Bergmann

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The changing landscape of biosimilars in rheumatology, Thomas Dorner, Vibeke Strand, Paul Cornes, Joao Goncalves, Laszlo Gulacsi, Jonathan Kay, Tore K. Kvien, Josef S. Smolen, Yoshiya Tanaka, and Gerd R. Burmester

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Levels of Ycg1 Limit Condensin Function during the Cell Cycle, Tyler W. Doughty, Heather E. Arsenault, and Jennifer A. Benanti

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Exploratory analysis of osteoarthritis progression among medication users: data from the Osteoarthritis Initiative, Jeffrey B. Driban, Grace H. Lo, Charles B. Eaton, Kate L. Lapane, Michael Nevitt, William F. Harvey, Charles E. McCulloch, and Timothy E. McAlindon

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The Secret Life of Tethers: The Role of Tethering Factors in SNARE Complex Regulation, Michelle L. Dubuke and Mary Munson

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Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations, Maria J. Duenas-Decamp, Li Jiang, Daniel N. Bolon, and Paul R. Clapham

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Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer, Zhou Du, Tong Sun, Ezgi Hacisuleyman, Teng Fei, Xiaodong Wang, Myles Brown, John L. Rinn, Mary Gwo-Shu Lee, Yiwen Chen, Philip W. Kantoff, and X. Shirley Liu

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Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3), Christopher J. Edwards, Francisco J. Blanco, Jeffrey Crowley, Charles Birbara, Janusz Jaworski, Jacob Aelion, Randall M. Stevens, Adele Vessey, Xiaojiang Zhan, and Paul Bird

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Complete Genome Sequences of Zika Virus Strains Isolated from the Blood of Patients in Thailand in 2014 and the Philippines in 2012, D. W. Ellison and Anon Srikiatkhachorn

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Using Mixed Methods to Examine the Role of Veterans' Illness Perceptions on Depression Treatment Utilization and HEDIS Concordance, A. Rani Elwy, Mark E. Glickman, Barbara G. Bokhour, Natalie S. Dell, Nora M. Mueller, Shibei Zhao, Princess E. Osei-Bonsu, Stephanie Rodrigues, Craig M. Coldwell, Tu A. Ngo, James Schlosser, Melanie J. Vielhauer, Paul A. Pirraglia, and Susan V. Eisen

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The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi, Jonatan Ersching, Jose Ronnie Vasconcelos, Camila P. Ferreira, Braulia C. Caetano, Alexandre Vieira Machado, Oscar Bruna-Romero, Monique A. Baron, Ludmila R.P. Ferreira, Edecio Cunha-Neto, Kenneth L. Rock, Ricardo T. Gazzinelli, and Mauricio Martins Rodrigues

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Anticonvulsive Effects of Licofelone on Status Epilepticus Induced by Lithium-pilocarpine in Wistar Rats: a Role for Inducible Nitric Oxide Synthase, Seyyed Majid Eslami, Mohammad Mobin Moradi, Mehdi Ghasemi, and Ahmad Reza Dehpour

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Factors associated with knowledge of a Good Samaritan Law among young adults who use prescription opioids non-medically, Tristan I. Evans, Scott E. Hadland, Melissa A. Clark, Traci C. Green, and Brandon D.L. Marshall

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A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice, Nicholas H. Farina, Areg Zingiryan, Jacqueline Akech, Cody J. Callahan, Huimin Lu, Janet L. Stein, Lucia R. Languino, Gary S. Stein, and Jane B. Lian

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Adipose-derived human stem/stromal cells: comparative organ specific mitochondrial bioenergy profiles, Alice S. Ferng, Katherine M. Marsh, Jamie M. Fleming, Renee F. Conway, David Schipper, Naing Bajaj, Alana M. Connell, Tia Pilikian, Kitsie Johnson, Ray Runyan, Stephen M. Black, John A. Szivek, and Zain Khalpey

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RNA activation of haploinsufficient Foxg1 gene in murine neocortex, Cristina Fimiani, Elisa Goina, Qin Su, Guangping Gao, and Antonello Mallamaci

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The Rivas Cohort Study: design and baseline characteristics of a Nicaraguan cohort, Madeline Fiore, Amos Lichtman, Keriann Nobil, and Louis Fiore