Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2017

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Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice, Patrick Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Aditya Ambade, Karen Kodys, Donna Catalano, Doyle V. Ward, and Gyongyi Szabo

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Visualization of self-delivering hydrophobically modified siRNA cellular internalization, Socheata Ly, Deanna M. Navaroli, Marie-Claire Didiot, James Cardia, Lakshmipathi Pandarinathan, Julia F. Alterman, Kevin E. Fogarty, Clive Standley, Lawrence Lifshitz, Karl D. Bellve, Matthieu Prot, Dimas Echeverria, Silvia Corvera, and Anastasia Khvorova

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Use of distal perfusion in peripheral extracorporeal membrane oxygenation, George Makdisi, Tony Makdisi, and I-Wen Wang

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Ethical challenges in extra corporeal membrane oxygenation use, Tony Makdisi and George Makdisi

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Extra corporeal membrane oxygenation support: ethical dilemmas, Tony Makdisi and George Makdisi

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A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes, Katherine R. Marino, Rachel L. Lundberg, Aastha Jasrotia, Louise Maranda, Michael J. Thompson, Bruce A. Barton, Laura C. Alonso, and Benjamin U. Nwosu

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Oral Health and Medicine Integration: Overcoming Historical Artifact to Relieve Suffering, Stephen A. Martin and Lisa Simon

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The p150N domain of chromatin assembly factor-1 regulates Ki-67 accumulation on the mitotic perichromosomal layer, Timothy D. Matheson and Paul D. Kaufman

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Patient Use of Electronic Prescription Refill and Secure Messaging and Its Association With Undetectable HIV Viral Load: A Retrospective Cohort Study, D. Keith McInnes, Stephanie L. Shimada, Amanda M. Midboe, Kim M. Nazi, Shibei Zhao, Justina Wu, Casey M. Garvey, and Thomas K. Houston

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Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors, David D. McManus, Jian Rong, Tianxiao Huan, Sean Lacey, Kahraman Tanriverdi, Peter J. Munson, Martin G. Larson, Roby Joehanes, Venkatesh Murthy, Ravi Shah, Jane E. Freedman, and Daniel Levy

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Screening of TNFalpha, IL-10 and TLR4 single nucleotide polymorphisms in individuals with asymptomatic and chronic cutaneous leishmaniasis in Colombia: a pilot study, Angelica Mera-Ramirez, Andres Castillo, Yenifer Orobio, Maria Adelaida. Gomez, and Carolina Gallego-Marin

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Can a nanoparticle that mimics Salmonella effectively combat tumor chemotherapy resistance, Regino Mercado-Lubo and Beth A. McCormick

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Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells, James R. C. Miller, Edith L. Pfister, Wanzhao Liu, Ralph Andre, Ulrike Trager, Lori A. Kennington, Kimberly Lo, Sipke Dijkstra, Douglas Macdonald, Gary R. Ostroff, Neil Aronin, and Sarah J. Tabrizi

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Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair, Kenta Moriwaki, Sakthi Balaji, John Bertin, Peter J. Gough, and Francis Ka-Ming Chan

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CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion, Haiwei Mou, Jordan L. Smith, Lingtao Peng, Jill Moore, Xiao-Ou Zhang, Chun-Qing Song, Ankur Sheel, Deniz M. Ozata, Yingxiang Li, Charles P. Emerson Jr., Erik J. Sontheimer, Melissa J. Moore, Zhiping Weng, and Wen Xue

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Culturally adaptive storytelling intervention versus didactic intervention to improve hypertension control in Vietnam: a cluster-randomized controlled feasibility trial, Hoa L. Nguyen, Jeroan J. Allison, Duc A. Ha, German Chiriboga, Ha N. Ly, Hanh T. Tran, Cuong K. Nguyen, Diem M. Dang, Ngoc T. Phan, Nguyen C. Vu, Quang P. Nguyen, and Robert J. Goldberg

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Ten-Year (2001-2011) Trends in the Incidence Rates and Short-Term Outcomes of Early Versus Late Onset Cardiogenic Shock After Hospitalization for Acute Myocardial Infarction, Hoa L. Nguyen, Jorge L. Yarzebski, Darleen M. Lessard, Joel M. Gore, David D. McManus, and Robert J. Goldberg

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Mammalian SWI/SNF Enzymes and the Epigenetics of Tumor Cell Metabolic Reprogramming, Jeffrey A. Nickerson, Qiong Wu, and Anthony N. Imbalzano

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Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness, Michiru Nishita, Seung-Yeol Park, Tadashi Nishio, Koki Kamizaki, ZhiChao Wang, Kota Tamada, Toru Takumi, Ryuju Hashimoto, Hiroki Otani, Gregory J. Pazour, Victor W. Hsu, and Yasuhiro Minami

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German translation, cultural adaptation, and validation of the Health Literacy Questionnaire (HLQ), Sandra Nolte, Richard H. Osborne, Sarah Dwinger, Gerald R. Elsworth, Melanie L. Conrad, Matthias S. F. Rose, Martin Harter, Jorg Dirmaier, and Jordis M. Zill

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Vitamin D status in pediatric irritable bowel syndrome, Benjamin U. Nwosu, Louise Maranda, and Ninfa Candela

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Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma, Cliff I. Oduor, Mercedeh Movassagh, Yasin Kaymaz, Kiprotich Chelimo, Juliana A. Otieno, John M. Ong'echa, Ann M. Moormann, and Jeffrey A. Bailey

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Decreased Functional Connectivity of Insular Cortex in Drug Naive First Episode Schizophrenia: In Relation to Symptom Severity, Lijuan Pang, David N. Kennedy, Qinling Wei, Luxian Lv, Jinsong Gao, Hong Li, Meina Quan, Xue Li, Yongfeng Yang, Xiaoduo Fan, and Xueqin Song

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Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration, Jillian N. Pearring, Jovenal T. San Agustin, Ekaterina S. Lobanova, Christopher J. Gabriel, Eric C. Lieu, William J. Monis, Michael W. Stuck, Lara Strittmatter, Samer M. Jaber, Vadim Y. Arshavsky, and Gregory J. Pazour

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Arteriovenous fistula patency in the 3 years following vonapanitase and placebo treatment, Eric K. Peden, Timothy P. O'Connor, Barry J. Browne, Bradley S. Dixon, Andres Schanzer, Stephen C. Jensik, Albert D. Sam 2nd, and Steven K. Burke

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Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA, Hannah M. Pendergraff, Pranathi Meda Krishnamurthy, Alexandre J. Debacker, Michael P. Moazami, Vivek K. Sharma, Liisa Niitsoo, Yong Yu, Yen Nee Tan, Hans Michael Haitchi, and Jonathan K. Watts

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Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice, Elizabeth M. Perez, Joslyn Foley, Timelia Tison, Rute Silva, and Javier Gordon Ogembo

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High-Grade Partial and Retracted (less than 2 cm) Proximal Hamstring Ruptures: Nonsurgical Treatment Revisited, Jonathan R. Piposar, Amrit V. Vinod, Joshua R. Olsen, Edward Lacerte, and Suzanne L. Miller

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Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications, Cesar A. Prada-Medina, Kiyoshi F. Fukutani, Nathella Pavan Kumar, Leonardo Gil-Santana, Subash Babu, Flavio Lichtenstein, Kim West, Shanmugam Sivakumar, Pradeep A. Menon, Vijay Viswanathan, Bruno B. Andrade, Helder I. Nakaya, and Hardy Kornfeld

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Missing the target: including perspectives of women with overweight and obesity to inform stigma-reduction strategies, Rebecca M. Puhl, M. S. Himmelstein, A. A. Gorin, and Young J. Suh

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MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression, Brian J. Quattrochi, Anushree Gulvady, David R. Driscoll, Makoto Sano, David S. Klimstra, Christopher E. Turner, and Brian C. Lewis

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Validity of the Nurses' health study physical activity questionnaire in estimating physical activity in adults with rheumatoid arthritis, Thomas Quinn, Michelle Frits, Johan von Heideken, Christine Iannaccone, Nancy A. Shadick, Michael Weinblatt, and Maura D. Iversen

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Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection, Kaitlin Rainwater-Lovett, Carrie Ziemniak, Douglas Watson, Katherine Luzuriaga, George Siberry, Ann Petru, YaHui Chen, Priyanka Uprety, Margaret M. McManus, Ya-Chi Ho, Susanna L. Lamers, and Deborah Persaud

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Clinical and demographic factors associated with change and maintenance of disease severity in a large registry of patients with rheumatoid arthritis, George W. Reed, David H. Collier, Andrew S. Koenig, Katherine C. Saunders, Dimitrios A. Pappas, Heather J. Litman, Joel M. Kremer, and Sameer Kotak

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On the Analysis of Intrahost and Interhost Viral Populations: Human Cytomegalovirus as a Case Study of Pitfalls and Expectations, Nicholas Renzette, Susanne P. Pfeifer, Sebastian Matuszewski, Timothy F. Kowalik, and Jeffrey D. Jensen

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Possible type 1 diabetes risk prediction: Using ultrasound imaging to assess pancreas inflammation in the inducible autoimmune diabetes BBDR model, Frederick R. Roberts, Clinton Hupple, Elaine Norowski, Nicole C. Walsh, Natalia Przewozniak, Ken-Edwin Aryee, Filia M. Van Dessel, Agata Jurczyk, David M. Harlan, Dale L. Greiner, Rita Bortell, and Chaoxing Yang

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ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation, Reddy Ranjith Kumar Sama, Claudia Fallini, Rodolfo Gatto, Jeanne E. McKeon, Yuyu Song, Melissa S. Rotunno, Saul Penaranda, Izrail Abdurakhmanov, John E. Landers, Gerardo Morfini, Scott T. Brady, and Daryl Bosco

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Beta-Blocker Use Is Associated With Impaired Left Atrial Function in Hypertension, Mayank Sardana, Amer Ahmed Syed, Zeba Hashmath, Timothy S. Phan, Maheswara R. Koppula, Uzma Kewan, Zoubair Ahmed, Ravikantha Chandamuri, Swapna Varakantam, Ejaz Shah, Ryan Gorz, Scott R. Akers, and Julio A. Chirinos

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Long-term cardiovascular mortality after radiotherapy for breast cancer: A systematic review and meta-analysis, Partha Sardar, Amartya Kundu, Saurav Chatterjee, Anju Nohria, Ramez Nairooz, Sripal Bangalore, Debabrata Mukherjee, Wilbert S. Aronow, and Carl J. Lavie

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Patient safety during procedural sedation using capnography monitoring: a systematic review and meta-analysis, Rhodri Saunders, Michel M.R.F. Struys, Richard F. Pollock, Michael Mestek, and Jenifer R. Lightdale

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miRNAs cooperate in apoptosis regulation during C. elegans development, Ryan Sherrard, Sebastian Luehr, Heinke Holzkamp, Katherine McJunkin, Nadin Memar, and Barbara Conradt

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Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY, Jade Shi, R Paul. Nobrega, Christian Schwantes, Sagar V. Kathuria, Osman Bilsel, C. Robert Matthews, T J. Lane, and Vijay S. Pande

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Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer, Yoshifumi Shimada, Stephen Lyle, and Toshifumi Wakai

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Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism, Jihae Shin, Ki Young Paek, Mariya Ivshina, Emily E. Stackpole, and Joel D. Richter

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When Breath Becomes Air [book review], Hugh Silk

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A Hybrid III stepped wedge cluster randomized trial testing an implementation strategy to facilitate the use of an evidence-based practice in VA Homeless Primary Care Treatment Programs, Molly M. Simmons, Sonya Gabrielian, Thomas Hugh Byrne, Megan B. McCullough, Jeffery L. Smith, Thom J. Taylor, Thomas P. O'Toole, Vincent Kane, Vera Yakovchenko, D. Keith McInnes, and David A. Smelson

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Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope, InYoung Song, Anna Gil, Rabinarayan Mishra, Dario Ghersi, Liisa K. Selin, and Lawrence J. Stern

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Prevalence of, and Resident and Facility Characteristics Associated With Antipsychotic Use in Assisted Living vs. Long-Term Care Facilities: A Cross-Sectional Analysis from Alberta, Canada, Kathryn J. Stock, Joseph E. Amuah, Kate L. Lapane, David B. Hogan, and Colleen J. Maxwell

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Child contact management in high tuberculosis burden countries: A mixed-methods systematic review, Daria Szkwarko, Yael Hirsch-Moverman, Lienki Du Plessis, Karen Du Preez, Catherine W. Carr, and Anna M. Mandalakas

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Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein, Maoxue Tang, Guangping Gao, Huapeng Li, Qin Su, Darryl C. De Vivo, and Umrao R. Monani

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Risk of Gastrointestinal Bleeding Among Dabigatran Users - A Self Controlled Case Series Analysis, Wenze Tang, Hsien-Yen Chang, Meijia Zhou, and Sonal Singh

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Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells, Bo Tian, Ahmad Al-Moujahed, Peggy Bouzika, Yijun Hu, Shoji Notomi, Pavlina Tsoka, Joan W. Miller, Haijiang Lin, and Demetrios G. Vavvas

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Circumstances of fall-related injuries by age and gender among community-dwelling adults in the United States, Lava R. Timsina, Joanna L. Willetts, Melanye J. Brennan, Helen Marucci-Wellman, David A. Lombardi, Theodore K. Courtney, and Santosh K. Verma

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A state-wide initiative to promote genetic testing in an underserved population, Meghan L. Underhill, Traci M. Blonquist, Karleen Habin, Debra Lundquist, Kristen Shannon, Kathryn Robinson, Mary-Lou Woodford, and Jean Boucher

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Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring, Markus P. Vallaster, Shweta Kukreja, Xin Y. Bing, Jennifer Ngolab, Rubing Zhao-Shea, Paul D. Gardner, Andrew R. Tapper, and Oliver J. Rando

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Humanized Mouse Models of Clinical Disease, Nicole C. Walsh, Laurie L. Kenney, Sonal Jangalwe, Ken-Edwin Aryee, Dale L. Greiner, Michael A. Brehm, and Leonard D. Shultz

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Microvascular response to transfusion in elective spine surgery, J. Matthias Walz, Ottokar Stundner, Federico P. Girardi, Bruce A. Barton, Aimee R. Kroll-Desrosiers, Stephen O. Heard, and Stavros G. Memtsoudis

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Resting-state functional connectivity changes within the default mode network and the salience network after antipsychotic treatment in early-phase schizophrenia, Yingchan Wang, Weijun Tang, Xiaoduo Fan, Jianye Zhang, Daoying Geng, Kaida Jiang, Dianming Zhu, Zhenhua Song, Zeping Xiao, and Dengtang Liu

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Metformin inhibits the proliferation of benign prostatic epithelial cells, Zongwei Wang, Xingyuan Xiao, Rongbin Ge, Jijun Li, Cameron W. Johnson, Cyrus Rassoulian, and Aria F. Olumi

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Altitude-Related Change in Endotracheal Tube Cuff Pressures in Helicopter EMS, Stacy Weisberg, Jonathan C. McCall Jr, and Joseph Tennyson

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Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis, Hai Wu, Jonathan A. Gordon R, Troy W. Whitfield, Phillip W. Tai L, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian

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(CCUG)n RNA toxicity in a Drosophila model of myotonic dystrophy type 2 (DM2) activates apoptosis, Vildan Betul Yenigun, Mario Sirito, Alla Amcheslavsky, Tomek Czernuszewicz, Jordi Colonques-Bellmunt, Irma Garcia-Alcover, Marzena Wojciechowska, Clare Bolduc, Zhihong Chen, Arturo Lopez Castel, Ralf Krahe, and Andreas Bergmann

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Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients, Shanye Yin, Rodrigo Lopez-Gonzalez, Ryan C. Kunz, Jaya Gangopadhyay, Carl Borufka, Steven P. Gygi, Fen-Biao Gao, and Robin Reed

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Lower school performance in late chronotypes: underlying factors and mechanisms, Giulia Zerbini, Vincent van der Vinne, Lana K. M. Otto, Thomas Kantermann, Wim P. Krijnen, Till Roenneberg, and Martha Merrow

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The Association between Breakfast Skipping and Body Weight, Nutrient Intake, and Metabolic Measures among Participants with Metabolic Syndrome, Lijuan Zhang, Lorraine S. Cordeiro, Jinghua Liu, and Yunsheng Ma

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Altered resting-state intra- and inter- network functional connectivity in patients with persistent somatoform pain disorder, Zhiyong Zhao, Tianming Huang, Chaozheng Tang, Kaiji Ni, Xiandi Pan, Chao Yan, Xiaoduo Fan, Dongrong Xu, and Yanli Luo

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Readability Formulas and User Perceptions of Electronic Health Records Difficulty: A Corpus Study, Jiaping Zheng and Hong Yu

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GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases, Lihua Julie Zhu, Michael Lawrence, Ankit Gupta, Herve Pages, Alper Kucukural, Manuel Garber, and Scot A. Wolfe

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Vibrotactile stimulation: A non-pharmacological intervention for opioid-exposed newborns, Ian Zuzarte, Premananda Indic, Bruce A. Barton, David Paydarfar, Francis Bednarek, and Elisabeth B. Salisbury

Publications from 2016

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Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome, Priyanka D. Abeyrathne, Cha San Koh, Timothy Grant, Nikolaus Grigorieff, and Andrei A. Korostelev

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Persistent Low-Level Replication of SIVDeltanef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection, Sama Adnan, Wenjun Li, and R. Paul Johnson

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A Modular Assembly Platform for Rapid Generation of DNA Constructs, Elliot Akama-Garren, Nik Joshi, Tuomas Tammela, Gregory P. Chang, Bethany L. Wagner, Da-Yae Lee, William M. Rideout Iii, Thales Papagiannakopoulos, Wen Xue, and Tyler Jacks

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The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity, Samer G. Alam, Qiao Zhang, Nripesh Prasad, Yuan Li, Srikar Chamala, Ram Kuchibhotla, Birendra Kc, Varun Aggarwal, Shristi Shrestha, Angela L. Jones, Shawn E. Levy, Kyle J. Roux, Jeffrey A. Nickerson, and Tanmay P. Lele

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Auditory Hallucinations and the Brain's Resting-State Networks: Findings and Methodological Observations, Ben Alderson-Day, Kelly Diederen, Charles Fernyhough, Judith M. Ford, Guillermo Horga, Daniel S. Margulies, Simon McCarthy-Jones, Georg Northoff, James M. Shine, Jessica Turner, Vincent van de Ven, Remko van Lutterveld, Flavie Waters, and Renaud Jardri

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Incidence of Dengue Virus Infection in Adults and Children in a Prospective Longitudinal Cohort in the Philippines, Maria Theresa Alera, Anon Srikiatkhachorn, John Mark Velasco, Ilya A. Tac-An, Catherine B. Lago, Hannah Clapham, Stefan Fernandez, Jens W. Levy, Butsaya Thaisomboonsuk, Chonticha Klungthong, Louis R. Macareo, Ananda Nisalak, Laura L. Hermann, Daisy Villa, and In-Kyu Yoon

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Culturally adaptive storytelling method to improve hypertension control in Vietnam - "We talk about our hypertension": study protocol for a feasibility cluster-randomized controlled trial, Jeroan J. Allison, Hoa L. Nguyen, Duc A. Ha, German A. Pihan, Ha N. Ly, Hanh T. Tran, Ngoc T. Phan, Nguyen C. Vu, Minjin Kim, and Robert J. Goldberg

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Examination of Huntington's disease with atypical clinical features in a Bangladeshi family tree, Md Mahfuz Al-Mamun, Suprovath Kumar Sarker, Syeda Kashfi Qadri, Tahmina Shirin, Quazi Deen Mohammad, Regina LaRocque, Elinor K. Karlsson, Narayan Saha, Muhammad Asaduzzaman, Firdausi Qadri, and Md Kaiissar Mannoor

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Glucose Metabolism Disorder Is Associated with Pulmonary Tuberculosis in Individuals with Respiratory Symptoms from Brazil, Jilson L. Almeida-Junior, Leonardo Gil-Santana, Carolina A.M. Oliveira, Simone Castro, Aparecida S. Cafezeiro, Carla Daltro, Eduardo M. Netto, Hardy Kornfeld, and Bruno B. Andrade

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Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease, Aditya Ambade, Abhishek Satishchandran, Benedek Gyongyosi, Patrick Lowe, and Gyongyi Szabo

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Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1alpha activation, Aditya Ambade, Abhishek Satishchandran, and Gyongyi Szabo

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Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4, Warrison A. Andrade, Sarika Agarwal, Shunyan Mo, Scott A. Shaffer, Joseph P. Dillard, Tobias Schmidt, Veit Hornung, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, and Douglas T. Golenbock

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Whole exome sequencing links dental tumor to an autosomal-dominant mutation in ANO5 gene associated with gnathodiaphyseal dysplasia and muscle dystrophies, T. V. Andreeva, T. V. Tyazhelova, V. N. Rykalina, F. E. Gusev, Andrey Y. Goltsov, O. I. Zolotareva, M. P. Aliseichik, T. A. Borodina, Anastasia P. Grigorenko, Denis Reshetov, E. K. Ginter, S. S. Amelina, R A. Zinchenko, and Evgeny I. Rogaev

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Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation, Eugenie Ansseau, Jocelyn O. Eidahl, Celine Lancelot, Alexandra Tassin, Christel Matteotti, Cassandre Yip, Jian Liu, Baptiste Leroy, Celine Hubeau, Cecile Gerbaux, Samuel Cloet, Armelle Wauters, Sabrina Zorbo, Pierre Meyer, Isabelle Pirson, Dalila Laoudj-Chenivesse, Ruddy Wattiez, Scott Q. Harper, Alexandra Belayew, and Frederique Coppee

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In vivo correction of anaemia in beta-thalassemic mice by gammaPNA-mediated gene editing with nanoparticle delivery, Raman Bahal, Dale L. Greiner, Michael A. Brehm, and Peter M. Glazer

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Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation, Mandar Bawadekar, Annette Gendron-Fitzpatrick, Ryan Rebernick, Daeun Shim, Thomas F. Warner, Anthony P. Nicholas, Lennart K. Lundblad A, Paul R. Thompson, and Miriam A. Shelef

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Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer, Marc A. Becker, Yasir H. Ibrahim, Annabell S. Oh, Dedra H. Fagan, Sara A. Byron, Aaron L. Sarver, Adrian V. Lee, Leslie M. Shaw, Cheng Fan, Charles M. Perou, and Douglas Yee

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microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration, Surjyadipta Bhattacharjee, Yuhai Zhao, Prerna Dua, Evgeny I. Rogaev, and Walter J. Lukiw

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Depression treatment decreases healthcare expenditures among working age patients with comorbid conditions and type 2 diabetes mellitus along with newly-diagnosed depression, Rituparna Bhattacharya, Chan Shen, Amy B. Wachholtz, Nilanjana Dwibedi, and Usha Sambamthoori

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MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations, Md Helal Uddin Biswas, Sandra Almeida, Rodrigo Lopez-Gonzalez, Wenjie Mao, Zhijun Zhang, Anna M. Karydas, Michael D. Geschwind, Jacek Biernat, Eva-Maria Mandelkow, Kensuke Futai, Bruce L. Miller, and Fen-Biao Gao

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Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses, Austin W. Boesch, Aaron J. Belli, Keith A. Reimann, and Margaret E. Ackerman

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Childhood traumatic experiences and mental health problems in sexually offending and non-sexually offending juveniles, Cyril Boonmann, Thomas Grisso, Laura S. Guy, Olivier F. Colins, Eva A. Mulder, P. Vahl, Lucres M. C. Jansen, Theo A. Doreleijers H, and Robert R. J. M. Vermeiren

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IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection, Matthew G. Booty, Palmira Barreira-Silva, Stephen Carpenter, Claudio Nunes-Alves, Miye K. Jacques, Britni L. Stowell, Pushpalatha Jayaraman, Gillian Beamer, and Samuel M. Behar

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Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates, Florie Borel, Gwladys Gernoux, Brynn Cardozo, Jake P. Metterville, Gabriela Toro Cabrera, Lina Song, Qin Su, Guang Ping Gao, Mai K. Elmallah, Robert H. Brown Jr., and Christian Mueller

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Corrigendum: FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons, Carles Bosch, Albert Martinez, Nuria Masachs, Catia M. Teixeira, Isabel Fernaud, Fausto Ulloa, Esther Perez-Martinez, Carlos Lois, Joan X. Comella, Javier DeFelipe, Angel Merchan-Perez, and Eduardo Soriano

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Implementation of a Computerized Screening Inventory: Improved Usability Through Iterative Testing and Modification, Edwin D. Boudreaux, Andrew Christopher Fischer, Brianna Haskins, Zubair Saeed Zafar, Guanling Chen, and Sneha A. Chinai

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A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis, Cara C. Boutte, Christina E. Baer, Kadamba Papavinasasundaram, Weiru Liu, Michael R. Chase, Xavier Meniche, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger, and Eric J. Rubin

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The Effect of Parathion on Red Blood Cell Acetylcholinesterase in the Wistar Rat, Naofumi Bunya, Keigo Sawamoto, Hanif Benoit, and Steven B. Bird

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Associations of Peripubertal Serum Dioxin and Polychlorinated Biphenyl Concentrations with Pubertal Timing among Russian Boys, Jane S. Burns, Mary M. Lee, Paige L. Williams, Susan A. Korrick, Oleg Sergeyev, Thuy Lam, Boris Revich, and Russ Hauser (Environmental health perspectives)

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xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation, Yi Cai, Subhalaxmi Nambi, Christopher M. Sassetti, Fudi Wang, and Xinchun Chen

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A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes, Michelle A. Carmell, Gregoriy A. Dokshin, Helen Skaletsky, Yueh-Chiang Hu, Josien C. van Wolfswinkel, Kyomi J. Igarashi, Daniel W. Bellott, Michael Nefedov, Peter W. Reddien, George C. Enders, Vladimir N. Uversky, Craig C. Mello, and David C. Page