Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2015

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HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages, Thomas A. Musich, Olivia O'Connell, Maria Paz Gonzalez-Perez, Cynthia A. Derdeyn, Paul J. Peters, and Paul R. Clapham

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Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities, Kamesh Narasimhan, Samuel A. Lambert, Ally Yang, Jeremy Riddell, Sanie Mnaimneh, Hong Zheng, Mihai Albu, Hamed S. Najafabadi, John S. Reece-Hoyes, Juan Fuxman Bass, Albertha J. M. Walhout, Matthew T. Weirauch, and Timothy R. Hughes

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Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila, Yingchao Nie, Qi Li, Alla Amcheslavsky, Juan Carlos Duhart, Alexey Veraksa, Hugo Stocker, Laurel A. Raftery, and Y. Tony Ip

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Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection, Claudio Nunes-Alves, Matthew G. Booty, Stephen M. Carpenter, Alissa C. Rothchild, Constance J. Martin, Danielle Desjardins, Katherine Steblenko, Henrik N. Kløverpris, Rajhmun Madansein, Duran Ramsuran, Alasdair Leslie, Margarida Correia-Neves, and Samuel M. Behar

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A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes, Benjamin U. Nwosu, Louise Maranda, Karen Cullen, Lisa Greenman, Jody Fleshman, Nancy McShea, Bruce A. Barton, and Mary M. Lee

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A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice, Javier Gordon Ogembo, Matthew R. Muraswki, Lori McGinnes, Agapi Parcharidou, Rujapak Sutiwisesak, Timelia Tison, Juan Avendano, Deep Agnani, Robert W. Finberg, Trudy G. Morrison, and Joyce D. Fingeroth

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Prevalence of Human Papillomavirus Genotypes among African Women with Normal Cervical Cytology and Neoplasia: A Systematic Review and Meta-Analysis, Rebecca Kemunto Ogembo, Philimon Gona, Alaina J. Seymour, Henry Soo-Min Park, Paul A. Bain, Louise Maranda, and Javier Gordon Ogembo

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Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels, Kelly H. Oh, Linu S. Abraham, Chandler Gegg, Christian Silvestri, Yung-Chi Huang, Mark J. Alkema, Jacob Furst, Daniela Raicu, and Hongkyun Kim

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Guanabenz (Wytensin) selectively enhances uptake and efficacy of hydrophobically modified siRNAs, Maire F. Osborn, Julia F. Alterman, Mehran Nikan, Hong Cao, Marie C. Didiot, Matthew R. Hassler, Andrew H. Coles, and Anastasia Khvorova

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Twitter-Delivered Behavioral Weight-Loss Interventions: A Pilot Series, Sherry L. Pagoto, Molly E. Waring, Kristin L. Schneider, Jessica L. Oleski, Effie Olendzki, Rashelle B. Hayes, Bradley M. Appelhans, Matthew C. Whited, Andrew M. Busch, and Stephenie C. Lemon

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Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis, Anil A. Panackal, Stuart M. Levitz, Bibi Bielekova, and Peter R. Williamson

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Microscopic colitis: A review of etiology, treatment and refractory disease, Tina Park, David R. Cave, and Christopher Marshall

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Perspectives in Implementing a Pragmatic Pediatric Primary Care-Based Intervention Trial, Lori Pbert, Susan Druker, Alan J. Flint, Martin H. Young, and Joseph R. DiFranza

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A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy, Isabela Resende Pereira, Glaucia Vilar-Pereira, Virginia Marques, Andrea Alice da Silva, Braulia Caetano, Otacilio Cruz Moreira, Alexandre Vieira Machado, Oscar Bruna-Romero, Mauricio Martins Rodrigues, Ricardo T. Gazzinelli, and Joseli Lannes-Vieira

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RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus, Jill Perreira, Aaron Aker, George Savidis, Christopher R. Chin, William M. McDougall, Jocelyn M. Portmann, Paul Meraner, Miles Smith, Motiur Rahman, Richard E. Baker, Annick Gauthier, Michael Franti, and Abraham L. Brass

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Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes, Paul J. Peters, Maria Paz Gonzalez-Perez, Thomas A. Musich, Tiffany A. Moore Simas, Rongheng Lin, Abraham N. Morse, Robin J. Shattock, Cynthia A. Derdeyn, and Paul R. Clapham

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Toward a sustainable biomedical research enterprise: Finding consensus and implementing recommendations, Christopher L. Pickett, Benjamin W. Corb, C. Robert Matthews, Wesley I. Sundquist, and Jeremy M. Berg

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Time-to-infection by Plasmodium falciparum is largely determined by random factors, Mykola Pinkevych, Kiprotich Chelimo, John Vulule, James W. Kazura, Ann M. Moormann, and Miles P. Davenport

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A Change in the Ion Selectivity of Ligand-Gated Ion Channels Provides a Mechanism to Switch Behavior, Jennifer K. Pirri, Diego Rayes, and Mark J. Alkema

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Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration, Massimo Pizzato, Sean Matthew McCauley, Martha R. Neagu, Thomas Pertel, Claudia Firrito, Serena Ziglio, Ann Dauphin, Madeleine Zufferey, Lionel Berthoux, and Jeremy Luban

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Figure-associated text summarization and evaluation, Balaji Polepalli Ramesh, Ricky J. Sethi, and Hong Yu

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Distal and Proximal Religiosity as Protective Factors for Adolescent and Emerging Adult Alcohol Use, Michelle V. Porche, Lisa R. Fortuna, Amy B. Wachholtz, and Rosalie A. Torres Stone

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Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase, Terence W. Prendiville, Haidong Guo, Zhiqiang Lin, Pingzhu Zhou, Sean M. Stevens, Aibin He, Nathan VanDusen, Jinghai Chen, Li Zhong, Da-Zhi Wang, Guangping Gao, and William T. Pu

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Variations in Community Prevalence and Determinants of Recreational and Utilitarian Walking in Older Age, Elizabeth Procter-Gray, Suzanne G. Leveille, Marian T. Hannan, Jie Cheng, Kevin J. Kane, and Wenjun Li

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Extracellular RNAs: development as biomarkers of human disease, Joseph F. Quinn, Tushar Patel, David Wong, Saumya Das, Jane Freedman, Louise C. Laurent, Bob S. Carter, Fred Hochberg, and Julie A. Saugstad

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Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis, Mayuri Rege, Vidya Subramanian, Chenchen Zhu, Tsung-Han S. Hsieh, Assaf Weiner, Nir Friedman, Sandra Clauder-Munster, Lars M. Steinmetz, Oliver J. Rando, Laurie A. Boyer, and Craig L. Peterson

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Patient safety incident capture resulting from incident reports: a comparative observational analysis, Martin A. Reznek, Kevin A. Kotkowski, Michael W. Arce, Zachary K. Jepson, Steven B. Bird, and Chad E. Darling

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Characterization of ST14A Cells for Studying Modulation of Voltage-Gated Calcium Channels, Mandy L. Roberts-Crowley and Ann R. Rittenhouse

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Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus, Raziel Rojas-Rodriguez, Tiffany A. Moore Simas, Lawrence M. Lifshitz, Karl D. Bellve, So-Yun Min, Jacqueline Pires, Katherine Leung, Crina Boeras, Aylin Sert, Jacqueline T. Draper, and Silvia Corvera

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The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1, Laurent Roybon, Teresa L. Mastracci, Joyce Li, Simon R. W. Stott, Andrew B. Leiter, Lori Sussel, Patrik Brundin, and Jia-Yi Li

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Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation, Christian K. Roy, Sara Olson, Brenton R. Graveley, Phillip D. Zamore, and Melissa J. Moore

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The yeast genome undergoes significant topological reorganization in quiescence, Mark T. Rutledge, Mariano Russo, Jon-Matthew Belton, Job Dekker, and James R. Broach

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Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors, Soroush T. Sarvestani, H. James Stunden, Mark A. Behlke, Samuel C. Forster, Claire E. McCoy, Michelle D. Tate, Jonathan Ferrand, Kim A. Lennox, Eicke Latz, Bryan R. G. Williams, and Michael P. Gantier

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Care that Matters: Quality Measurement and Health Care, Barry G. Saver, Stephen A. Martin, Ronald N. Adler, Lucy M. Candib, Konstantinos E. Deligiannidis, Jeremy Golding, Daniel J. Mullin, Michele Roberts, and Stefan Topolski

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A practice-based randomized controlled trial to improve medication adherence among Latinos with hypertension: study protocol for a randomized controlled trial, Antoinette Schoenthaler, Franzenith De La Calle, Miguel Barrios-Barrios, Aury Garcia, Maria Pitaro, Audrey Lum, and Milagros C. Rosal

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HiC-Pro: an optimized and flexible pipeline for Hi-C data processing, Nicolas Servant, Nelle Varoquaux, Bryan R. Lajoie, Eric Viara, Chong-Jian Chen, Jean-Philippe Vert, Edith Heard, Job Dekker, and Emmanuel Barillot

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Cognition and mood-related behaviors in l3mbtl1 null mutant mice, Erica Y. Shen, Yan Jiang, Wenjie Mao, Kensuke Futai, Hanno Hock, and Schahram Akbarian

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Annotation of suprachromosomal families reveals uncommon types of alpha satellite organization in pericentromeric regions of hg38 human genome assembly, V. A. Shepelev, L. I. Uralsky, A. A. Alexandrov, Y. B. Yurov, Evgeny I. Rogaev, and I. A. Alexandrov

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Vitamin D3 Supplemental Treatment for Mania in Youth with Bipolar Spectrum Disorders, Elif M. Sikoglu, Ana A. Liso Navarro, Debra Starr, Yael Dvir, Benjamin U. Nwosu, Suzanne M. Czerniak, Ryan C. Rogan, Martha C. Castro, Richard A.E. Edden, Jean A. Frazier, and Constance M. Moore

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A cluster randomized Hybrid Type III trial testing an implementation support strategy to facilitate the use of an evidence-based practice in VA homeless programs, David A. Smelson, Matthew Chinman, Sharon McCarthy, Gordon Hannah, Leon Sawh, and Mark Glickman

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A 4D view on mRNA, Carlas Smith, Li-Chun Tu, and David Grünwald

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Multimodal imaging measures predict rearrest, Vaughn R. Steele, Eric D. Claus, Eyal Aharoni, Gina M. Vincent, Vince D. Calhoun, and Kent A. Kiehl

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An efficient and sensitive method for preparing cDNA libraries from scarce biological samples, Catherine H. Sterling, Isana Veksler-Lublinsky, and Victor R. Ambros

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Disrupted seasonal biology impacts health, food security and ecosystems, T. J. Stevenson, M. E. Visser, W. Arnold, P. Barrett, S. Biello, A. Dawson, D. L. Denlinger, D. Dominoni, F. J. Ebling, S. Elton, and William J. Schwartz

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Bilateral Intracranial Vertebral Artery Stenosis Presenting as Recurrent Prolonged Presyncopal Episodes, Banu Sundar, Majaz Moonis, Ajay K. Wakhloo, and Ajit S. Puri

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Dynamical features of the Plasmodium falciparum ribosome during translation, Ming Sun, Wen Li, Karin Blomqvist, Sanchaita Das, Yaser Hashem, Jeffrey D. Dvorin, and Joachim Frank

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Oldenlandia diffusa Promotes Antiproliferative and Apoptotic Effects in a Rat Hepatocellular Carcinoma with Liver Cirrhosis, Yun-Young Sunwoo, Jin-Hee Lee, Ho Yong Jung, Yu Jin Jung, Moon-Seo Park, Yong-An Chung, Lee-So Maeng, Young-Min Han, Hak Soo Shin, Jisoo Lee, and Sang In Park

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Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records, Matthew Sussman, Jeffrey Trocio, Craig Best, Sebastian Mirkin, Andrew G. Bushmakin, Robert A. Yood, Mark Friedman, Joseph Menzin, and Michael Louie

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Current role of radiation therapy for multiple myeloma, Giampaolo Talamo, Christopher Dimaio, Kamal K. S. Abbi, Manoj K. Pandey, Jozef Malysz, Michael H. Creer, Junjia Zhu, Muhammad A. Mir, and John Varlotto

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Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells, Daniel J. Trombly, Troy W. Whitfield, Srivatsan Padmanabhan, Jonathan A. R. Gordon, Jane B. Lian, Andre J. Van Wijnen, Kaleem Zaidi, Janet L. Stein, and Gary S. Stein

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Comparative functional characterization of the CSR-1 22G-RNA pathway in Caenorhabditis nematodes, Shikui Tu, Monica Z. Wu, Jie Wang, Asher D. Cutter, Zhiping Weng, and Julie M. Claycomb

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Distinguishing grade I meningioma from higher grade meningiomas without biopsy, John Varlotto, John Flickinger, Martin T. Pavelic, Charles S. Specht, Jonas M. Sheehan, Dana T. Timek, Michael J. Glantz, Steven Sogge, Christopher Dimaio, Richard P. Moser, Shakeeb Yunus, Thomas J. Fitzgerald, Urvashi Upadhyay, Paul Rava, Matthew Tangel, Aaron Yao, and Sangam Kanekar

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Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice, Aditya Venkatesh, Shan Ma, Yun Z. Le, Michael N. Hall, Markus A. Ruegg, and Claudio Punzo

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An effective approach to diagnosis and surgical repair of refractory medial epicondylitis, Amrit V. Vinod and Glen Ross

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Weekly Treatment of 2-Hydroxypropyl-beta-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice, Sofie M.A. Walenbergh, Tom Houben, Tim Hendrikx, Mike L.J. Jeurissen, Patrick J. van Gorp, Nathalie Vaes, Steven W.M. Olde Damink, Fons Verheyen, Ger H. Koek, Dieter Lutjohann, Alena Grebe, Eicke Latz, and Ronit Shiri-Sverdlov

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Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi's Granuloma: The Consequences of Skin Barrier Dysfunction, Tao Wang, Chenchen Xu, Xiping Zhou, Chunjia Li, Hongbing Zhang, Bill Q. Lian, Jonathan J. Lee, Jun Shen, Yuehua Liu, and Christine Guo Lian

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Evaluation of smoking-specific and generic quality of life measures in current and former smokers in Germany and the United States, John E. Ware Jr., Barbara L. Gandek, Anuradha Kulasekaran, and Rick Guyer

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Cervical cancer screening and follow-up in 4 geographically diverse US health care systems, 1998 through 2007, Sheila Weinmann, Andrew E. Williams, Aruna Kamineni, Diana S.M. Buist, Erin E. Masterson, Natasha K. Stout, Azadeh Stark, Tyler R. Ross, Christopher L. Owens, Terry S. Field, and Chyke A. Doubeni

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Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection, Darin L. Wiesner, Charles A. Specht, Chrono K. Lee, Kyle D. Smith, Liliane Mukaremera, S. Thera Lee, Chun G. Lee, Jack A. Elias, Judith N. Nielsen, David R. Boulware, Paul R. Bohjanen, Marc K. Jenkins, Stuart M. Levitz, and Kirsten Nielsen

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Studies of OC-STAMP in Osteoclast Fusion: A New Knockout Mouse Model, Rescue of Cell Fusion, and Transmembrane Topology, Hanna Witwicka, Sung-Yong Hwang, Pablo Reyes-Gutierrez, Hong Jia, Paul E. Odgren, Leah Rae Donahue, Mark J. Birnbaum, and Paul R. Odgren

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TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption, Hanna Witwicka, Hong Jia, Artem B. Kutikov, Pablo Reyes-Gutierrez, Xiang-Dong Li, and Paul R. Odgren

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TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection, Tuoqi Wu, HyunMu Shin, E. Ashley Moseman, Yun Ji, Bonnie Huang, Christelle Harly, Jyoti M. Sen, Leslie J. Berg, Luca Gattinoni, Dorian B. McGavern, and Pamela L. Schwartzberg

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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets, Chaoxing Yang, Matthias Loehn, Agata Jurczyk, Natalia Przewozniak, Linda Leehy, Pedro L. Herrera, Leonard D. Shultz, Dale L. Greiner, David Harlan, and Rita Bortell

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FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions, Dejun Yang, Abbas Abdallah, Zhaodong Li, Yubing Lu, Sandra Almeida, and Fen-Biao Gao

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Discriminating Active Tuberculosis from Latent Tuberculosis Infection by flow cytometric measurement of CD161-expressing T cells, Qianting Yang, Qian Xu, Qi Chen, Jin Li, Mingxia Zhang, Yi Cai, Haiying Liu, Yiping Zhou, Guofang Deng, Qunyi Deng, Boping Zhou, Hardy Kornfeld, and Xinchun Chen

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Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response, Seungchan Yang, Alexandre Jose Christino Quaresma, Jeffrey A. Nickerson, Karin M. Green, Scott A. Shaffer, Anthony N. Imbalzano, Lori A. Martin-Buley, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein

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Osteopetrorickets due to Snx10 deficiency in mice results from both failed osteoclast activity and loss of gastric acid-dependent calcium absorption, Liang Ye, Leslie R. Morse, Li Zhang, Hajime Sasaki, Jason C. Mills, Paul R. Odgren, Greg Sibbel, James R.L. Stanley, Gee Wong, Ariane Zamarioli, and Ricardo A. Battaglino

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DeTEXT: A Database for Evaluating Text Extraction from Biomedical Literature Figures, Xu-Cheng Yin, Chun Yang, Wei-Yi Pei, Haixia Man, Jun Zhang, Erik Learned-Miller, and Hong Yu

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High rate of subclinical chikungunya virus infection and association of neutralizing antibody with protection in a prospective cohort in the Philippines, In-Kyu Yoon, Maria Theresa Alera, Catherine B. Lago, Ilya A. Tac-An, Daisy Villa, Stefan Fernandez, Butsaya Thaisomboonsuk, Chonticha Klungthong, Jens W. Levy, John Mark Velasco, Vito G. Roque Jr., Henrik Salje, Louis R. Macareo, Laura L. Hermann, Ananda Nisalak, and Anon Srikiatkhachorn

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Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila, Yeliz Yuva-Aydemir, Xia-Lian Xu, Ozkan Aydemir, Eduardo Gascon, Serkan Sayin, Wenke Zhou, Yang Hong, and Fen-Biao Gao

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Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing, Li Zhang, Ngoc-Tung Tran, Hairui Su, Rui Wang, Yuheng Lu, Haiping Tang, Sayura Aoyagi, Ailan Guo, Alireza Khodadadi-Jamayran, Dewang Zhou, Kun Qian, Todd Hricik, Jocelyn Cote, Xiaosi Han, Wenping Zhou, Suparna Laha, Omar Abdel-Wahab, Ross L. Levine, Glen Raffel, Yanyan Liu, Dongquan Chen, Haitao Li, Tim Townes, Hengbin Wang, Haiteng Deng, Yujun George Zheng, Christina Leslie, Minkui Luo, and Xinyang Zhao

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Cluster-based Epidemic Control Through Smartphone-based Body Area Networks, Zhaoyang Zhang, Honggang Wang, Chonggang Wang, and Hua (Julia) Fang

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A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation, Huaying Zhao, Kimberly A. Crowley, Craig L. Peterson, Sarah G. Swygert, and Peter Schuck

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Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes, Jiali Zhuang and Zhiping Weng

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Progression of Large Lymphoma Is Significantly Impeded with a Combination of Gemcitabine Chemotherapy and Dendritic Cells Intra-Tumor Vaccination, Xue-Jun Zhu, Zhongfa Yang, Jin-Yong Zhou, Li Liu, Xue-Mei Sun, Zhen-Fang Fan, Shou-You Hu, Yu-Chao Chen, Wei-Xia Li, Meng Cao, and Li-Xin Wang

Publications from 2014

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Induction of IL-12 production in human peripheral monocytes by Trypanosoma cruzi Is mediated by glycosylphosphatidylinositol-anchored mucin-like glycoproteins and potentiated by IFN- gamma and CD40-CD40L interactions, Lucia Cristina Abel Jamli, Ludmila Rodrigues Ferreira Pinto, Isabela Cunha Navarro, Monique Andrade Baron, Jorge Kalil, Ricardo T. Gazzinelli, Luiz Vicente Rizzo, and Edecio Cunha-Neto

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Post-Autologous (ASCT) Stem Cell Transplant Therapy in Multiple Myeloma, Zeina Al-Mansour and Muthalagu Ramanathan

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The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria, Lis R.V. Antonelli, Fabiana M.S. Leoratti, Pedro A.C. Costa, Bruno C. Rocha, Suelen Q. Diniz, Mauro S. Tada, Dhelio B. Pereira, Andrea Teixeira-Carvalho, Douglas T. Golenbock, Ricardo Goncalves, and Ricardo T. Gazzinelli

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The home environment and childhood obesity in low-income households: indirect effects via sleep duration and screen time, Bradley M. Appelhans, Stephanie L. Fitzpatrick, Hong Li, Vernon Cail, Molly E. Waring, Kristin L. Schneider, Matthew C. Whited, Andrew M. Busch, and Sherry L. Pagoto

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Genetic vaccination against experimental infection with myotropic parasite strains of Trypanosoma cruzi, Adriano Fernando Araujo, Gabriel de Oliveira, Juliana Fraga Vasconcelos, Jonatan Ersching, Mariana Ribeiro Dominguez, Jose Ronnie Vasconcelos, Alexandre Vieira Machado, Ricardo T. Gazzinelli, Oscar Bruna-Romero, Milena Botelho Soares, and Mauricio Martins Rodrigues

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Human breast progenitor cell numbers are regulated by WNT and TBX3, Lisa M. Arendt, Jessica St. Laurent, Ania Wronski, Silvia Caballero, Stephen Lyle, Stephen P. Naber, and Charlotte Kuperwasser

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Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection, Marco A. Ataide, Warrison A. Andrade, Dario S. Zamboni, Donghai Wang, Maria do Carmo Souza, Bernardo S. Franklin, Samir Elian, Flaviano S. Martins, Dhelio Pereira, George W. Reed, Katherine A. Fitzgerald, Douglas T. Golenbock, and Ricardo T. Gazzinelli

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NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone, Junya Awata, Saeko Takada, Clive Standley, Karl-Ferdinand Lechtreck, Karl D. Bellve, Gregory J. Pazour, Kevin E. Fogarty, and George B. Witman

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Joint replacement registries in the United States: a new paradigm, David C. Ayers and Patricia D. Franklin

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High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody, Gregory J. Babcock, Sowmya Iyer, Heidi L. Smith, Yan Wang, Kirk Rowley, Donna M. Ambrosino, Phillip D. Zamore, Brian G. Pierce, Deborah C. Molrine, and Zhiping Weng

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Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals, Shashi Bala, Miguel Marcos, Arijeet Gattu, Donna Catalano, and Gyongyi Szabo

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Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan, Ankita Bansal, Eun-Soo Kwon, Darryl Conte Jr., Haibo Liu, Michael J. Gilchrist, Lesley T. MacNeil, and Heidi A. Tissenbaum

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Protective immunity and safety of a genetically modified influenza virus vaccine, Rafael Polidoro Alves Barbosa, Ana Paula Carneiro Salgado, Cristiana Couto Garcia, Bruno Galvao Filho, Ana Paula de Faria Paula de Faria Goncalves, Braulio Henrique Freire Lima, Gabriel Augusto Oliveira Lopes, Milene Alvarenga Rachid, Andiara Cristina Cardoso Peixoto, Danilo Bretas de Oliveira, Marco Antonio Ataide, Carla Aparecida Zirke, Tatiane Marques Cotrim, Erica Azevedo Costa, Gabriel Magno de Freitas Almeida, Remo Castro Russo, Ricardo T. Gazzinelli, and Alexandre de Magalhaes Vieira Machado

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The relationship between subnormal peak-stimulated growth hormone levels and auxological characteristics in obese children, Jefferson Barrett, Louise S. Maranda, and Benjamin U. Nwosu

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Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA, Hanni Bartels and Jeremy Luban

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The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter, Rasim Barutcu, Phillip W. Tai, Hai Wu, Jonathan A. R. Gordon, Troy W. Whitfield, Jason Dobson, Anthony N. Imbalzano, Jane B. Lian, Andre J. van Wijnen, Janet L. Stein, and Gary S. Stein

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A conserved dopamine-cholecystokinin signaling pathway shapes context-dependent Caenorhabditis elegans behavior, Raja Bhattacharya, Denis Touroutine, Belinda Barbagallo, Jason Climer, Christopher M. Lambert, Christopher M. Clark, Mark J. Alkema, and Michael M. Francis

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The spatial dynamics of dengue virus in Kamphaeng Phet, Thailand, Piraya Bhoomiboonchoo, Robert V. Gibbons, Angkana Huang, In-Kyu Yoon, Darunee Buddhari, Ananda Nisalak, Natkamol Chansatiporn, Mathuros Thipayamongkolgul, Siripen Kalanarooj, Timothy Endy, Alan L. Rothman, Anon Srikiatkhachorn, Sharone Green, Mammen P. Mammen, Derek A. Cummings, and Henrik Salje

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A survey study of evidence-based medicine training in US and Canadian medical schools, Maria A. Blanco, Carol F. Capello, Josephine L. Dorsch, Gerald (Jerry) Perry, and Mary L. Zanetti

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A randomized controlled trial of mental health interventions for survivors of systematic violence in Kurdistan, Northern Iraq, Paul Bolton, Judith K. Bass, Goran Zangana, Talar Kamal, Sarah Murray, Debra Kaysen, Carl W. Lejuez, Kristen Lindgren, Sherry L. Pagoto, Laura K. Murray, Stephanie Van Wyk, Ahmed Ahmed, Nazar M. Mohammad Amin, and Michael Rosenblum

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Dengue virus neutralizing antibody levels associated with protection from infection in Thai cluster studies, Darunee Buddhari, Jared Aldstadt, Timothy P. Endy, Anon Srikiatkhachorn, Butsaya Thaisomboonsuk, Chonticha Klungthong, Ananda Nisalak, Benjawan Khuntirat, Richard G. Jarman, Stefan Fernandez, Stephen J. Thomas, Thomas W. Scott, Alan L. Rothman, and In-Kyu Yoon

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Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90, Terence N. Bukong, Fatemeh Momen-Heravi, Karen Kodys, Shashi Bala, and Gyongyi Szabo

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A deterministic model predicts the properties of stochastic calcium oscillations in airway smooth muscle cells, Pengxing Cao, Xiahui Tan, Graham Donovan, Michael J. Sanderson, and James Sneyd

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Antiplatelet activity, P2Y(1) and P2Y(1)(2) inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'''-P(1) ,P(4)-dithio-P(2),P(3)-chloromethylenetetraphosphate, Hung Chang, Ivan B. Yanachkov, Edward J. Dix, Milka Yanachkova, Youfu Li, Marc R. Barnard, George E. Wright, Alan D. Michelson, and Andrew L. Frelinger III

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Estudio Parto: postpartum diabetes prevention program for hispanic women with abnormal glucose tolerance in pregnancy: a randomised controlled trial - study protocol, Lisa Chasan-Taber, Bess H. Marcus, Milagros C. Rosal, Katherine L. Tucker, Sheri J. Hartman, Penelope S. Pekow, Barry Braun, Tiffany A. Moore Simas, Caren G. Solomon, Joann E. Manson, and Glenn Markenson