Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2016

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A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice, Nicholas H. Farina, Areg Zingiryan, Jacqueline Akech, Cody J. Callahan, Huimin Lu, Janet L. Stein, Lucia R. Languino, Gary S. Stein, and Jane B. Lian

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Adipose-derived human stem/stromal cells: comparative organ specific mitochondrial bioenergy profiles, Alice S. Ferng, Katherine M. Marsh, Jamie M. Fleming, Renee F. Conway, David Schipper, Naing Bajaj, Alana M. Connell, Tia Pilikian, Kitsie Johnson, Ray Runyan, Stephen M. Black, John A. Szivek, and Zain Khalpey

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RNA activation of haploinsufficient Foxg1 gene in murine neocortex, Cristina Fimiani, Elisa Goina, Qin Su, Guangping Gao, and Antonello Mallamaci

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The Rivas Cohort Study: design and baseline characteristics of a Nicaraguan cohort, Madeline Fiore, Amos Lichtman, Keriann Nobil, and Louis Fiore

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www.common-metrics.org: a web application to estimate scores from different patient-reported outcome measures on a common scale, H. Felix Fischer and Matthias S. F. Rose

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Impairments of Social Motor Synchrony Evident in Autism Spectrum Disorder, Paula Fitzpatrick, Jean A. Frazier, David E. Cochran, Teresa V. Mitchell, Caitlin Coleman, and R C. Schmidt

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Encouraging Patient Portal Use in the Patient-Centered Medical Home: Three Stakeholder Perspectives, Gemmae M. Fix, Timothy P. Hogan, Daniel J. Amante, D. Keith McInnes, Kim M. Nazi, and Steven R. Simon

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A chimeric protein-based malaria vaccine candidate induces robust T cell responses against Plasmodium vivax MSP119, Jairo Andres Fonseca, Monica Cabrera-Mora, Balwan Singh, Joseli Oliveira-Ferreira, Josue Da Costa Lima-Junior, J. Mauricio Calvo-Calle, Jose Manuel Lozano, and Alberto Moreno

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Diverse human extracellular RNAs are widely detected in human plasma, Jane E. Freedman, Eric Mick, Lea M. Beaulieu, Selim E. Tanriverdi, Milka Koupenova-Zamor, Ekaterina Mikhalev, and Kahraman Tanriverdi

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A Delphi process to address medication appropriateness for older persons with multiple chronic conditions, Terri R. Fried, Kristina Niehoff, Jennifer Tjia, Nancy Redeker, and Mary K. Goldstein

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Recombinant AAV Vectors for Enhanced Expression of Authentic IgG, Sebastian P. Fuchs, Jose M. Martinez-Navio, Guangping Gao, and Ronald C. Desrosiers

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Sexual Dimorphism in Alcohol Induced Adipose Inflammation Relates to Liver Injury, Melissa A. Fulham and Pranoti Mandrekar

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Keeping Weight Off: study protocol of an RCT to investigate brain changes associated with mindfulness-based stress reduction, Carl E. Fulwiler, Julia A. Siegel, Jeroan J. Allison, Milagros C. Rosal, Judson A. Brewer, and Jean A. King

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A gene-centered C. elegans protein-DNA interaction network provides a framework for functional predictions, Juan Fuxman Bass, Carles Pons, Lucie Kozlowski, John S. Reece-Hoyes, Shaleen Shrestha, Amy D. Holdorf, Akihiro Mori, Chad L. Myers, and Albertha J. M. Walhout

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ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics, Jozsef Gal, Lisha Kuang, Kelly R. Barnett, Brian Z. Zhu, Susannah C. Shissler, Konstantin V. Korotkov, Lawrence J. Hayward, Edward J. Kasarskis, and Haining Zhu

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Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure, Stefanie Gauguet, Kate Madden, Jennifer Wu, Christine Duncan, Gi Soo Lee, Tonya Miller, William C. Klingensmith 4th, Sandra K. Burchett, and Meredith van der Velden

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Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion, Daniel Tianfang Ge, Cindy Tipping, Michael H. Brodsky, and Phillip D. Zamore

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Expansion of the Knockdown Resistance Frequency Map for Human Head Lice (Phthiraptera: Pediculidae) in the United States Using Quantitative Sequencing, Kyle J. Gellatly, Sarah Krim, Daniel J. Palenchar, Katie Shepherd, Kyong Sup Yoon, Christopher J. Rhodes, Si Hyeock Lee, and J. Marshall Clark

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Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment, Eliver Eid Ghosn Bou, Jeffrey Waters, Megan Phillips, Ryo Yamamoto, Brian R. Long, Yang Yang, Rachel M. Gerstein, Cheryl A. Stoddart, Hiromitsu Nakauchi, and Leonore A. Herzenberg

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Diabetes Is Associated with Worse Clinical Presentation in Tuberculosis Patients from Brazil: A Retrospective Cohort Study, Leonardo Gil-Santana, Jilson L. Almeida-Junior, Carolina A.M. Oliveira, Lucas S. Hickson, Carla Daltro, Simone Castro, Hardy Kornfeld, Eduardo M. Netto, and Bruno B. Andrade

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The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4, Megan M. Gnazzo, Eva-Maria E. Uhlemann, Alex R. Villarreal, Masaki Shirayama, Eddie G. Dominguez, and Ahna R. Skop

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Spontaneous coronary artery dissection in a patient with autosomal dominant polycystic kidney disease: a case report, Peeyush Grover and Timothy P. Fitzgibbons

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Self-Complementary Adeno-Associated Virus Vectors Improve Transduction Efficiency of Corneal Endothelial Cells, Anja K. Gruenert, Marta Czugala, Christian Mueller, Marco Schmeer, Martin Schleef, Friedrich E. Kruse, and Thomas A. Fuchsluger

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Genomic insights into the Ixodes scapularis tick vector of Lyme disease, Monika Gulia-Nuss,; Daniel R. Caffrey; Neal S. Silverman; Adam R. Wespiser; and Catherine A. Hill

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Regulation of chaperone binding and nucleosome dynamics by key residues within the globular domain of histone H3, Sarah J. Hainer and Joseph A. Martens

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DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells, Sarah J. Hainer, Kurtis N. McCannell, Jun Yu, Ly-Sha Ee, Lihua (Julie) Zhu, Oliver J. Rando, and Thomas G. Fazzio

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Septate Junction Proteins Play Essential Roles in Morphogenesis Throughout Embryonic Development in Drosophila, Sonia Hall and Robert E. Ward 4th

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Light-Mediated Deep-Tissue Theranostics, Gang Han and Jin Xie

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High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources, Reka A. Haraszti, Marie-Cecile Didiot, Ellen Sapp, John D. Leszyk, Scott A. Shaffer, Hannah E. Rockwell, Fei Gao, Niven R. Narain, Marian DiFiglia, Michael A. Kiebish, Neil Aronin, and Anastasia Khvorova

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Identifying factors associated with concordance with the American College of Rheumatology rheumatoid arthritis treatment recommendations, Leslie R. Harrold, George Reed, Joel Kremer, Jeffrey R. Curtis, Daniel H. Solomon, Marc Hochberg, Arthur Kavanaugh, Katherine C. Saunders, Ying Shan, Tanya M. Spruill, Dimitrios A. Pappas, and Jeffrey D. Greenberg

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Menopausal vasomotor symptoms and incident breast cancer risk in the Study of Women's Health Across the Nation, Vicki Hart, Susan R. Sturgeon, Nicholas Reich, Lynnette Leidy Sievert, Sybil L. Crawford, Ellen B. Gold, Nancy E. Avis, and Katherine W. Reeves

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Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species, Jiang He, Ruobo Zhou, Zhuhao Wu, Monica A. Carrasco, Peri T. Kurshan, Jonathan E. Farley, David J. Simon, Guiping Wang, Boran Han, Junjie Hao, Evan Heller, Marc R. Freeman, Kang Shen, Tom Maniatis, Marc Tessier-Lavigne, and Xiaowei Zhuang

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Forward genetic screen of human transposase genomic rearrangements, Anton G. Henssen, Eileen Jiang, Jiali Zhuang, Luca Pinello, Nicholas D. Socci, Richard Koche, Mithat Gonen, Camila M. Villasante, Scott A. Armstrong, Daniel E. Bauer, Zhiping Weng, and Alex Kentsis

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Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria, Isabella C. Hirako, Marco Antonio Ataide, Lucas Faustino, Patricia A. Assis, Elizabeth W. Sorensen, Hisashi Ueta, Natalia M. Araujo, Gustavo B. Menezes, Andrew D. Luster, and Ricardo T. Gazzinelli

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Data Citation in Neuroimaging: Proposed Best Practices for Data Identification and Attribution, Leah B. Honor, Christian Haselgrove, Jean A. Frazier, and David N. Kennedy

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Single molecule analysis reveals reversible and irreversible steps during spliceosome activation, Aaron A. Hoskins, Margaret L. Rodgers, Larry J. Friedman, Jeff Gelles, and Melissa J. Moore

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Hypercalcemia due to Primary Hepatic Lymphoma, Andrew Hsu, Michael Gagnier, Elizabeth Ryer, Mohammed Salhab, and Alan G. Rosmarin

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Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes, Henry Huang, Eric S. Veien, Hong Zhang, David C. Ayers, and Jie Song

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Monitoring cell-cell contacts in vivo in transgenic animals, Ting-Hao Huang, Tarciso Velho, and Carlos Lois

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Epstein-Barr Virus Infection of Mammary Epithelial Cells Promotes Malignant Transformation, Hai Hu, Joyce D. Fingeroth, and Gerburg M. Wulf

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A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI network, Elena V. Ignatieva, Dmitry A. Afonnikov, Olga V. Saik, Evgeny I. Rogaev, and Nikolay A. Kolchanov

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Small Molecule Inhibitor of CBFbeta-RUNX Binding for RUNX Transcription Factor Driven Cancers, Anuradha Illendula, John A. Pulikkan, Lucio H. Castilla, and John H. Bushweller

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An Intact Dissecting Baker's Cyst Mimicking Recurrent Deep Vein Thrombosis, Sarah Jamshed and L. Michael Snyder

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Improved B cell development in humanized NOD-scid IL2Rgammanull mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3, Sonal Jangalwe, Leonard D. Shultz, Anuja Mathew, and Michael A. Brehm

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GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis, Guillaume Jannot, Pascale Michaud, Miguel Quevillon Huberdeau, Louis Morel-Berryman, James A. Brackbill, Sandra Piquet, Katherine McJunkin, Kotaro Nakanishi, and Martin J. Simard

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Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice, Adam Jara, Xingbo Liu, Don Sim, Chance M. Benner, Silvana Duran-Ortiz, Yanrong Qian, Edward O. List, Darlene E. Berryman, Jason K. Kim, and John J. Kopchick

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TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection, Pushpalatha Jayaraman, Miye K. Jacques, Chen Zhu, Katherine Steblenko, Britni L. Stowell, Asaf Madi, Ana C. Anderson, Vijay K. Kuchroo, and Samuel M. Behar

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Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo, Hyein Jeon, Jae Hwan Kim, Eunjung Lee, Young Jin Jang, Joe Eun Son, Jung Yeon Kwon, Tae-Gyu Lim, Sunghoon Kim, Jung Han Yoon Park, Jong-Eun Kim, and Ki Won Lee

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Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD), Takako I. Jones, Megan Parilla, and Peter L. Jones

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Results of a Culturally Adapted Internet-Enhanced Physical Activity Pilot Intervention for Overweight and Obese Young Adult African American Women, Rodney P. Joseph, Dori Pekmezi, Gareth R. Dutton, Andrea Cherrington, Young-Il Kim, Jeroan J. Allison, and Nefertiti H. Durant

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Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery, Nikolaos Kakouros, Saman Nazarian, Patrizia B. Stadler, Thomas Kickler, and Jeffrey J. Rade

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Seasonal Variations and Trends in Hospitalization for Peptic Ulcer Disease in the United States: A 12-Year Analysis of the Nationwide Inpatient Sample, Ritesh Kanotra, Moiz Ahmed, Nileshkumar Patel, Badal Thakkar, Shantanu Solanki, Sarah Tareen, Matthew J. Fasullo, Mayurathan Kesavan, Nikhil Nalluri, Ahsan Khan, Dhaval Pau, Liliane Deeb, Jeffrey Abergel, and Ananya Das

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Massachusetts Health Reform Cost Less and Was More Effective for Uninsured Individuals With Venous Thromboembolism: A Cost-Effectiveness Analysis, Alok Kapoor, Nicholas Shaffer, Amresh Hanchate, Mark Roberts, and Kenneth Smith

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A Model to Explain How the Bacille Calmette Guerin (BCG) Vaccine Drives Interleukin-12 Production in Neonates, Chido Loveness Kathivu and Daniel H. Libraty

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Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses, Joanna Kawalkowska, Anne-Marie Quirke, Fatemeh Ghari, Simon Davis, Venkataraman Subramanian, Paul R. Thompson, Richard O. Williams, Roman Fischer, Nicholas B. La Thangue, and Patrick J. Venables

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Five-year Safety Data from 5 Clinical Trials of Subcutaneous Golimumab in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis, Jonathan Kay, Roy Fleischmann, Edward Keystone, Elizabeth C. Hsia, Benjamin Hsu, Yiying Zhou, Neil Goldstein, and Jurgen Braun

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NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548, Hao Ke, Limin Zhao, Xu Feng, Haibo Xu, Li Zou, Qin Yang, Xiaosan Su, Lingtao Peng, and Baowei Jiao

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Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012, Nomana M. Khan, Emily S. Jentes, Clive Brown, Pauline Han, Sowmya R. Rao, Phyllis Kozarsky, Stefan H.F. Hagmann, Regina C. LaRocque, Edward T. Ryan, and Global TravEpiNet Consortium (GTEN)

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ChREBP Regulates Fructose-induced Glucose Production Independently of Insulin Signaling, Mi-Sung Kim, Sarah A. Krawczyk, Ludivine Doridot, Alan J. Fowler, Jennifer X. Wang, Sunia A. Trauger, Hye Lim Noh, Hee Joon Kang, John K. Meissen, Matthew Blatnik, Jason K. Kim, Michelle Lai, and Mark A. Herman

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Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study), Darae Ko, David D. McManus, and Michael Rienstra

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Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin, Tomohiro Kubo, Jason Brown, Karl D. Bellve, Branch Craige, Julie M. Craft, Kevin E. Fogarty, Karl-Ferdinand Lechtreck, and George B. Witman (Journal of cell science)

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Impact of Microbiota on Resistance to Ocular Pseudomonas aeruginosa-Induced Keratitis, Abirami Kugadas, Stig Hill Christiansen, Saiprasad Sankaranarayanan, Neeraj K. Surana, Stefanie Gauguet, Ryan Kunz, Raina Fichorova, Thomas Vorup-Jensen, and Mihaela Gadjeva

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"Walking in a maze": community providers' difficulties coordinating health care for homeless patients, Terri LaCoursiere Zucchero, Sarah McDannold, and D. Keith McInnes

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Palliative cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion: current clinical practice or misnomer, Laura A. Lambert and Ariana Harris

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A USP28-53BP1-p53-p21 signaling axis arrests growth after centrosome loss or prolonged mitosis, Bramwell G. Lambrus, Vikas Daggubati, Yumi Uetake, Phillip M. Scott, Kevin M. Clutario, Greenfield Sluder, and Andrew J. Holland (The Journal of cell biology)

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Highlights from the 6th International Meeting on Emerging Diseases and Surveillance (IMED 2016) Vienna, Austria from Nov 3 to 7, 2016, Britta Lassmann and Lawrence C. Madoff

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Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase, Scott E. LeBlanc, Qiong Wu, Pallavi Lamba, Said Sif, and Anthony N. Imbalzano (Nucleic acids research)

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Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation, Jane J. Lee, Kathryn A. Britton, Alison Pedley, Joseph Massaro, Elizabeth K. Speliotes, Joanne M. Murabito, Udo Hoffmann, Cheryl Ingram, John F. Keaney, Ramachandran S. Vasan, and Caroline S. Fox

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Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study, Jane J. Lee, Alison Pedley, Udo Hoffmann, Joseph Massaro, John F. Keaney Jr., Ramachandran S. Vasan, and Caroline S. Fox

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Relationship between Massachusetts Youth Screening Instrument-second version and psychiatric disorders in youths in welfare and juvenile justice institutions in Switzerland, L E. W. Leenarts, C. Dolitzsch, K. Schmeck, J. M. Fegert, Thomas Grisso, and M. Schmid

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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease, Peter L. Lee, Yuefeng Tang, Huawei Li, and David A. Guertin

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Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration, Sang Goo Lee, Mingqian Huang, Nikolaus D. Obholzer, Shan Sun, Wenyan Li, Marco Petrillo, Pu Dai, Yi Zhou, Douglas A. Contanche, Sean G. Megason, Huawei Li, and Zheng-Yi Chen (PloS one)

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CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN, Diana Legarda, Scott J. Justus, Rosalind L. Ang, Nimisha Rikhi, Wenjing Li, Thomas M. Moran, Jianke Zhang, Emiko Mizoguchi, Matija Zelic, Michelle A. Kelliher, J. Magarian Blander, and Adrian T. Ting

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Consensus Paper: Cerebellar Development, Ketty Leto, Baojin Ding, and Daniel Lee Kilpatrick

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External validation of the DHAKA score and comparison with the current IMCI algorithm for the assessment of dehydration in children with diarrhoea: a prospective cohort study, Adam C. Levine, Justin Glavis-Bloom, Payal Modi, Sabiha Nasrin, Bita Atika, Soham Rege, Sarah Robertson, Christopher H. Schmid, and Nur H. Alam

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Access to substance use treatment among young adults who use prescription opioids non-medically, Elliott J. Liebling, Jesse L. Yedinak, Traci C. Green, Scott E. Hadland, Melissa A. Clark, and Brandon D.L. Marshall

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Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland, Guangyuan Li, Isaac N. Hayward, Brittany R. Jenkins, Heather M. Rothfuss, Coleman H. Young, Marja T. Nevalainen, Aaron Muth, Paul R. Thompson, Amy M. Navratil, and Brian D. Cherrington

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Stem cells with a view: a look inside a retinal ciliopathy, Linjing Li and Hemant Khanna

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Autophagy-independent function of Atg1 for apoptosis-induced compensatory proliferation, Mingli Li, Jillian L. Lindblad, Ernesto Perez, Andreas Bergmann, and Yun Fan

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Thirty-day outcomes underestimate endocrine and exocrine insufficiency after pancreatic resection, Pei-Wen Lim, Kate H. Dinh, Mary E. Sullivan, Wahid Y. Wassef, Jaroslav Zivny, Giles F. Whalen, and Jennifer LaFemina

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Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress, Chen Lin, Xinyuan Zhao, Desen Sun, Lingda Zhang, Wenpan Fang, Tingjia Zhu, Qiang Wang, Botao Liu, Saisai Wei, Guangdi Chen, Zhengping Xu, and Xiangwei Gao

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Combining statistics from two national complex surveys to estimate injury rates per hour exposed and variance by activity in the USA, Tin-Chi Lin, Helen R. Marucci-Wellman, Joanna L. Willetts, Melanye J. Brennan, and Santosh K. Verma

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Activation of mTORC1 is essential for beta-adrenergic stimulation of adipose browning, Dianxin Liu, Marica Bordicchia, Chaoying Zhang, Huafeng Fang, Wan Wei, Jian-Liang Li, Adilson L. Guilherme, Kalyani V. P. Guntur, Michael P. Czech, and Sheila Collins

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Implementation and reporting of causal mediation analysis in 2015: a systematic review in epidemiological studies, Shao-Hsien Liu, Christine M. Ulbricht, Stavroula A. Chrysanthopoulou, and Kate L. Lapane

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DNA immunization as a technology platform for monoclonal antibody induction, Shuying Liu, Shixia Wang, and Shan Lu

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Does the Mutant CAG Expansion in Huntingtin mRNA Interfere with Exonucleolytic Cleavage of its First Exon, Wanzhao Liu, Edith L. Pfister, Lori A. Kennington, Kathryn O. Chase, Christian Mueller, Marian DiFiglia, and Neil Aronin

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Preserving Patient Privacy When Sharing Same-Disease Data, Xiaoping Liu, Xiao-Bai Li, Luvai Motiwalla, Wenjun Li, Hua Zheng, and Patricia D. Franklin

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Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy, Y. Lucy Liu, Shaoguang Li, and Peter D. Emanuel

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Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study, Wenyuan Li, John F. Keaney Jr., and Murray A. Mittleman

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DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia, You Li, Hisato Yagi, Gregory M. Hendricks, Gregory J. Pazour, and Cecilia W. Lo

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Coalicion de Salud Comunitaria (COSACO): using a Healthy Community Partnership framework to integrate short-term global health experiences into broader community development, Lawrence C. Loh, Olga Valdman, and Matthew M. Dacso

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Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells, Cecilia Lopez-Sambrooks, Shiteshu Shrimal, Carol Khodier, Daniel P. Flaherty, Natalie Rinis, Jonathan C. Charest, Ningguo Gao, Peng Zhao, Lance Wells, Timothy A. Lewis, Mark A. Lehrman, Reid Gilmore, Jennifer E. Golden, and Joseph N. Contessa

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Ribosome*RelA structures reveal the mechanism of stringent response activation, Anna B. Loveland, Eugene Bah, Rohini Madireddy, Ying Zhang, Axel F. Brilot, Nikolaus Grigorieff, and Andrei A. Korostelev

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Closing the net on retroviruses, Jeremy Luban

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Older Veteran Digital Disparities: Examining the Potential for Solutions Within Social Networks, Tana M. Luger, Timothy P. Hogan, Lorilei M. Richardson, Lisa Cioffari-Bailiff, Kimberly Harvey, and Thomas K. Houston

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The Causes of HIV-Associated Cardiomyopathy: A Tale of Two Worlds, Rebecca H. Lumsden and Gerald S. Bloomfield

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Accurate Prediction of Transposon-Derived piRNAs by Integrating Various Sequential and Physicochemical Features, Longqiang Luo, Dingfang Li, Wen Zhang, Shikui Tu, Xiaopeng Zhu, and Gang Tian

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Safety of anticoagulation with uninterrupted warfarin vs. interrupted dabigatran in patients requiring an implantable cardiac device, Shivanshu Madan, Purushothaman Muthusamy, Katie L. Mowers, Darryl A. Elmouchi, Bohuslav Finta, Andre J. Gauri, Alan K. Woelfel, Timothy D. Fritz, Alan T. Davis, and Nagib T. Chalfoun

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Decade Long Trends (2001-2011) in Duration of Pre-Hospital Delay Among Elderly Patients Hospitalized for an Acute Myocardial Infarction, Raghavendra Makam, Nathaniel Erskine, Jorge L. Yarzebski, Darleen M. Lessard, Jason Lau, Jeroan J. Allison, Joel M. Gore, Jerry H. Gurwitz, David D. McManus, and Robert J. Goldberg

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Association between Responsible Pet Ownership and Glycemic Control in Youths with Type 1 Diabetes, Louise Maranda and Olga T. Gupta