Title

Metastatic papillary thyroid carcinoma to lung diagnosed by bronchoalveolar lavage

UMMS Affiliation

Department of Pathology; Department of Medicine, Division of Endocrinology and Metabolism; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care

Date

1-1-1996

Document Type

Article

Subjects

Adult; Bronchoalveolar Lavage Fluid; Carcinoma, Papillary; Female; Humans; Lung Neoplasms; Thyroid Neoplasms

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

The diagnosis of papillary carcinoma of the thyroid metastatic to the lung frequently requires a battery of noninvasive tests. Occasionally, invasive procedures such as open lung biopsy, transthoracic needle biopsy, and transbronchial lung biopsy are employed to confirm the diagnosis. A 31-yr-old woman with papillary thyroid carcinoma treated previously by a near-total thyroidectomy and 131I ablation presented to our clinic with shortness of breath and a clear chest roentgenogram. A post-131I treatment whole body scan revealed widespread 131I pulmonary uptake, and the presence of papillary thyroid cancer was confirmed by bronchoalveolar lavage. We conclude that bronchoalveolar lavage should be considered when tissue confirmation of metastatic papillary carcinoma to the lung is needed. During the evaluation and follow-up of this patient, we were able to determine that metastatic papillary carcinoma to the lung may cause a methacholine bronchoprovocation test to be falsely positive for asthma.

Rights and Permissions

Citation: J Clin Endocrinol Metab. 1996 Jan;81(1):406-10.

Related Resources

Link to Article in PubMed

Journal Title

The Journal of clinical endocrinology and metabolism

PubMed ID

8550785