Phage lambda red-mediated adaptive mutation
Department of Molecular Genetics and Microbiology
Adaptation, Physiological; Bacteriophage lambda; Chromosomes, Bacterial; Escherichia coli; Lac Operon; *Mutation; *Recombination, Genetic; Transformation, Bacterial
Life Sciences | Medicine and Health Sciences
Replacement of the recBCD genes of Escherichia coli with the red recombination genes of bacteriophage lambda results in a strain in which adaptive mutation occurs at an elevated frequency. Like RecBCD-dependent adaptive mutation, Red-mediated adaptive mutation is dependent upon recA and ruvABC functions.
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Citation: J Bacteriol. 2002 Jul;184(13):3753-5.
Journal of bacteriology
Poteete, Anthony R.; Wang, Hsinju R.; and Foster, Patricia L., "Phage lambda red-mediated adaptive mutation" (2002). Open Access Articles. 656.