Rapid resolution of acute cor pulmonale with recombinant tissue plasminogen activator
Department of Medicine, Division of Cardiovascular Medicine
Acute Disease; Aged; Female; Humans; Pulmonary Embolism; Pulmonary Heart Disease; Recombinant Proteins; Tissue Plasminogen Activator
Life Sciences | Medicine and Health Sciences
A case of massive pulmonary embolism complicated by acute cor pulmonale and shock is presented. The IV administration of recombinant tissue-type plasminogen activator (rt-PA) was associated with prompt reversal of clinical, ECG, and nuclear radiographic findings. The role of thrombolytic therapy with rt-PA for massive pulmonary embolism associated with hemodynamic decompensation deserves further investigation.
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Citation: Chest. 1989 Oct;96(4):939-41.
Gore, Joel M.; Thompson, Michael J.; and Becker, Richard C., "Rapid resolution of acute cor pulmonale with recombinant tissue plasminogen activator" (1989). Open Access Articles. 443.