UMMS Affiliation

Clinical Pharmacy Services, Commonwealth Medicine



Document Type



Anesthesia and Analgesia | Health Services Administration | Pharmacy and Pharmaceutical Sciences


Objective: To evaluate usage patterns of dexmedetomidine in the operating room after implementation of a prescribing guideline.

Methods: We conducted a retrospective analysis to evaluate the impact of a prescribing guideline on usage patterns of dexmedetomidine in the operating room at a tertiary, academic medical center during one-month period pre- (July 2010) and post-guideline (July 2011 and July 2012) implementation.

Results: A total of 267 patients received intraoperative dexmedetomidine during the study period. Dexmedetomidine use in surgical procedures decreased post-guideline implementation [5.7% (pre) vs. 1.9% and 3.3% (post)]. The most common guideline-based indication for intraoperative dexmedetomidine was for anesthesia during bariatric surgery (41% and 38% in 2011 and 2012, respectively). We estimated a cost-avoidance of $308,856 over the two-year period after guideline implementation.

Conclusion: Our results suggest that implementation of a prescribing guideline for the use of dexmedetomidine in the operating room is feasible and associated with improved utilization patterns.

Rights and Permissions

© 2016 The Authors. Open Access funded by King Saud University. Citation: Saudi Pharm J. 2017 Jan;25(1):144-147. Epub 2016 Jan 14. Link to article on publisher's site

DOI of Published Version


Related Resources

Link to Article in PubMed


prescribing guideline, dexmedetomidine, operating room

Journal Title

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

PubMed ID


Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.



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