UMMS Affiliation

Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School

Publication Date

5-27-2005

Document Type

Article

Disciplines

Molecular and Cellular Neuroscience | Neuroscience and Neurobiology | Psychiatry

Abstract

In the present paper we review a series of experiments showing that heritable variations in the size of the hippocampal intra- and infrapyramidal mossy fiber (IIPMF) terminal fields correlate with performance in spatial, but not non-spatial radial-maze tasks. Experimental manipulation of the size of this projection by means of early postnatal hyperthyroidism produces the effects predicted from the correlations obtained with inbred mouse strains. Although the physiological mechanisms behind these correlations are unknown as yet, several lines of evidence indicate that these correlations are causal.

Rights and Permissions

Citation: Behav Brain Funct. 2005 Apr 22;1(1):3. Link to article on publisher's site

DOI of Published Version

10.1186/1744-9081-1-3

Related Resources

Link to article in PubMed

Journal/Book/Conference Title

Behavioral and Brain Functions [electronic resource].

PubMed ID

15916698

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.