Making enhancers from spare parts of the genome
Program in Bioinformatics and Integrative Biology
Animals; Biological Evolution; Conserved Sequence; *Enhancer Elements, Genetic; Exons; Gene Duplication; *Genes, Developmental; *Genes, Regulator; *Genome; Humans; Mice; Sharks; Smegmamorpha
Genetics and Genomics | Life Sciences | Medicine and Health Sciences
New studies show that novel long-range enhancers of developmental genes can emerge by exaptation of protein-coding sequences with no previous regulatory function.
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Citation: Genome Biol. 2011 Dec 29;12(12):138. Link to article on publisher's site