Reduced-representation methylation mapping
Department of Biochemistry and Molecular Pharmacology
Animals; Cytosine; *DNA Methylation; Epigenesis, Genetic; Genomics; Mice; Sequence Analysis, DNA
Genetics and Genomics | Life Sciences | Medicine and Health Sciences
The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.
Jeddeloh, Jeffrey A.; Greally, John M.; and Rando, Oliver J., "Reduced-representation methylation mapping" (2008). Open Access Articles. 2259.