Title

Autophagy SEPArates germline and somatic cells

UMMS Affiliation

Department of Cancer Biology

Date

1-27-2009

Document Type

Article

Subjects

Animals; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cytoplasmic Granules; Germ Cells

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.

Rights and Permissions

Citation: Cell. 2009 Jan 23;136(2):207-8. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

19167322