Title
Autophagy SEPArates germline and somatic cells
PubMed ID
19167322
UMMS Affiliation
Department of Cancer Biology
Date
1-27-2009
Document Type
Article
Subjects
Animals; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cytoplasmic Granules; Germ Cells
Disciplines
Life Sciences | Medicine and Health Sciences
Abstract
Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.
Rights and Permissions
Citation: Cell. 2009 Jan 23;136(2):207-8. Link to article on publisher's site
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