Autophagy SEPArates germline and somatic cells
Department of Cancer Biology
Animals; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cytoplasmic Granules; Germ Cells
Life Sciences | Medicine and Health Sciences
Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.
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Citation: Cell. 2009 Jan 23;136(2):207-8. Link to article on publisher's site