Title

Integrin signaling aberrations in prostate cancer

PubMed ID

19956432

UMMS Affiliation

Department of Cancer Biology

Date

12-4-2009

Document Type

Article

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

Integrins are cell surface receptors for extracellular matrix proteins and play a key role in cell survival, proliferation, migration and gene expression. Integrin signaling has been shown to be deregulated in several types of cancer, including prostate cancer. This review is focused on integrin signaling pathways known to be deregulated in prostate cancer and known to promote prostate cancer progression.

Rights and Permissions

Citation: Am J Transl Res. 2009 Apr 20;1(3):211-20.

Related Resources

Link to Article in PubMed