Integrin signaling aberrations in prostate cancer
Department of Cancer Biology
Life Sciences | Medicine and Health Sciences
Integrins are cell surface receptors for extracellular matrix proteins and play a key role in cell survival, proliferation, migration and gene expression. Integrin signaling has been shown to be deregulated in several types of cancer, including prostate cancer. This review is focused on integrin signaling pathways known to be deregulated in prostate cancer and known to promote prostate cancer progression.
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Citation: Am J Transl Res. 2009 Apr 20;1(3):211-20.